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Scientists Are Getting Seriously Worried About Synthetic Smallpox (sciencealert.com)

An anonymous reader quotes ScienceAlert: Earlier this year, scientists published a paper describing how they pieced together segments of DNA in order to bring back a previously eradicated virus called horsepox. The paper, written by two University of Alberta researchers and the co-founder of a New York pharmaceutical company, was controversial because, as various experts told the magazine Science, someone could use a very similar process to bring back a related virus: smallpox. Smallpox, you'll recall, killed hundreds of millions of people before the World Health Organization declared it eradicated in 1980. That was the result of a long vaccination campaign — so the idea of piecing the virus back together from bits of DNA raises the specter of a horrifying pandemic.

Two journals rejected the paper before PLOS One, an open access peer-reviewed journal, published it. Critics argue that the paper not only demonstrates that you can synthesize a deadly pathogen for what Science reported was about US$100,000 in lab expenses, but even provides a slightly-too-detailed-for-comfort overview of how to do it. Some of the horsepox scientists' coworkers are still pretty upset about this. PLOS One's sister Journal, PLOS Pathogens, just published three opinion pieces about the whole flap, as well as a rebuttal by the Canadian professors. Overall, everyone's pretty polite. But you get the sense that microbiologists are really, really worried about someone reviving smallpox. MIT biochemist Kevin Esvelt, for instance, wrote on Thursday that the threat is so grim that we shouldn't even talk about it.

3 of 93 comments (clear)

  1. This is the least of our worries by Anonymous Coward · · Score: 2, Funny

    Hubble went dead last week, followed by Chandra this week. Am I the only one that sees what is happening here? What's the first thing you do before you invade a country? Blind them. Take out their eyes and ears, their radar installations, etc. Then you send in the forces. With Earth effectively blinded I bet there are massive battle cruisers hidden in the asteroid belt that are even now powering up their engines and finalizing battle plans. Wake up people!!!!

  2. Re:I was vaccinated by olsmeister · · Score: 3, Funny

    Wait are you saying that unmodified smallpox could selectively take out the hipsters and millennials? Whoa, hold on, I need to rethink this.

  3. horsepox? by Hognoxious · · Score: 3, Funny

    As Col. Potter would say, cowfeathers!

    --
    Confucius say, "Find worm in apple - bad. Find half a worm - worse."