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Scientists Are Getting Seriously Worried About Synthetic Smallpox (sciencealert.com)

An anonymous reader quotes ScienceAlert: Earlier this year, scientists published a paper describing how they pieced together segments of DNA in order to bring back a previously eradicated virus called horsepox. The paper, written by two University of Alberta researchers and the co-founder of a New York pharmaceutical company, was controversial because, as various experts told the magazine Science, someone could use a very similar process to bring back a related virus: smallpox. Smallpox, you'll recall, killed hundreds of millions of people before the World Health Organization declared it eradicated in 1980. That was the result of a long vaccination campaign — so the idea of piecing the virus back together from bits of DNA raises the specter of a horrifying pandemic.

Two journals rejected the paper before PLOS One, an open access peer-reviewed journal, published it. Critics argue that the paper not only demonstrates that you can synthesize a deadly pathogen for what Science reported was about US$100,000 in lab expenses, but even provides a slightly-too-detailed-for-comfort overview of how to do it. Some of the horsepox scientists' coworkers are still pretty upset about this. PLOS One's sister Journal, PLOS Pathogens, just published three opinion pieces about the whole flap, as well as a rebuttal by the Canadian professors. Overall, everyone's pretty polite. But you get the sense that microbiologists are really, really worried about someone reviving smallpox. MIT biochemist Kevin Esvelt, for instance, wrote on Thursday that the threat is so grim that we shouldn't even talk about it.

2 of 93 comments (clear)

  1. Oh please, what's the worst that could happen? by Gravis+Zero · · Score: 3, Interesting

    Come on, it's not like we are dangerously unprepared for pandemic.

    A few months ago, a disease caused by an engineered biological weapon played the antagonist in a fictional outbreak scenario that ended with more than 100 million dead and the global economy crippled.

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    Anons need not reply. Questions end with a question mark.
  2. Re: Can we just make more vaccine by Anonymous Coward · · Score: 1, Interesting

    Somewhere between the usual revisionist history and tinfoil hats.

    Remember folks, if white people invent or discovered something, within a year Chinese "scholars" will find proof that they did it first. Conveniently with evidence that no westerner is allowed to see and verify. Wait a decade or two and the humanities department will find a way to inject black slaves or oppressed women as the real saviors of the west.