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Fasting Can Improve Overall Health By Causing Circadian Clocks In the Liver and Skeletal Muscle To Rewire Their Metabolism, Study Finds (sciencedaily.com)

An anonymous reader quotes a report from ScienceDaily: In a University of California, Irvine-led study, researchers found evidence that fasting affects circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against aging-associated diseases. The study was published recently in Cell Reports. The research was conducted using mice, which were subjected to 24-hour periods of fasting. While fasting, researchers noted the mice exhibited a reduction in oxygen consumption (VO2), respiratory exchange ratio (RER), and energy expenditure, all of which were completely abolished by refeeding, which parallels results observed in humans.

"The reorganization of gene regulation by fasting could prime the genome to a more permissive state to anticipate upcoming food intake and thereby drive a new rhythmic cycle of gene expression. In other words, fasting is able to essentially reprogram a variety of cellular responses. Therefore, optimal fasting in a timed manner would be strategic to positively affect cellular functions and ultimately benefiting health and protecting against aging-associated diseases." This study opens new avenues of investigation that could ultimately lead to the development of nutritional strategies to improve health in humans.

3 of 216 comments (clear)

  1. Re:Fasting worked wonders for my health. by Pinky's+Brain · · Score: 1, Flamebait

    Having been a fatso a priori eliminates you as someone suitable to give diet advice, dieting maybe ... but not diet.

    Leave healthy people alone and stick with your own, fatties.

  2. Re:Look for the agenda by Anonymous Coward · · Score: 0, Flamebait

    LOL "french fries".

    They are called chips, you illiterate, uncultured fuck.

  3. Re:Fasting worked wonders for my health. by Anonymous Coward · · Score: 0, Flamebait

    Seems not many notice the sarcasm.
    just sticking to food that's been on the planet for longer than 100 years
    All human food ingredient exist on earth for more than 100 years. But few can screen out further domestication.

    No processed chemical foods
    All cooking process involve chemical transformation.

    Down from 40's to 34's and even 32's after about 9 months of sticking to real food
    32 pounds = 14.5kg. Weight of a 8 years old kid.

    Don't believe me, prove me wrong.
    Unless one with a gene that growth no taller than 3 feets, 40 pounds basically spell mulnutritions.