Fasting Can Improve Overall Health By Causing Circadian Clocks In the Liver and Skeletal Muscle To Rewire Their Metabolism, Study Finds (sciencedaily.com)

An anonymous reader quotes a report from ScienceDaily: In a University of California, Irvine-led study, researchers found evidence that fasting affects circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against aging-associated diseases. The study was published recently in Cell Reports. The research was conducted using mice, which were subjected to 24-hour periods of fasting. While fasting, researchers noted the mice exhibited a reduction in oxygen consumption (VO2), respiratory exchange ratio (RER), and energy expenditure, all of which were completely abolished by refeeding, which parallels results observed in humans.

"The reorganization of gene regulation by fasting could prime the genome to a more permissive state to anticipate upcoming food intake and thereby drive a new rhythmic cycle of gene expression. In other words, fasting is able to essentially reprogram a variety of cellular responses. Therefore, optimal fasting in a timed manner would be strategic to positively affect cellular functions and ultimately benefiting health and protecting against aging-associated diseases." This study opens new avenues of investigation that could ultimately lead to the development of nutritional strategies to improve health in humans.

Comments

Re:Don't like the science? Wait a few years

[Ichijo]

500 years ago, everybody knew that the Earth was flat.

False.

Re:Don't like the science? Wait a few years

[Shaitan]

It's a quote from the movie Men in Black

Re:Look for the agenda

[antek9]

I know you're trolling, but allow me to bite: Vegan doctrine doesn't include fasting, moreover, vegans love carbs and get fat if they don't also afford a nutrition coach. Muslims don't know the first thing about fasting, Ramadan is a joke: not even water during daytime, only to eat triple the normal daily amount all night long is NOT intermittent fasting, it's binge eating with a cooldown phase.

Keto and fasting (comes naturally, the hunger just goes away) for the win, and you can keep eating those steaks. But throw away the potato.

Re: Look for the agenda

[Anonymous Coward]

Going in ketosis is not that hard. Sub 20 grams carbs/day is enough for most people.
 
When I was going keto last year, I had my Ketones checked at work (im a hospital microbiologist), I was in ketosis within a couple weeks.

Re:Look for the agenda

[angel'o'sphere]

Potatoes are not that bad.
McDonalds style french fries are, especially if you top them with ketchup and majonaise (hint: look up how french fries are supposed to look).
The real problem is pasta from simple flour, white bread, the typical US processed rice, corn syrup in stuff where it simply does not belong, pizza with to much of everything. The "oversize" attitude. Artificial sweeteners in your drinks that completely mess up the digesting system.

Re:Look for the agenda

[houghi]

I live in Belgium, we know not only how fries supposed to look, but also that double frying is the answer to soggy fries. And you are supposed to eat them like this

I think I just gained a kilo just looking at those images.