you are right on the money anon coward
it is simplu insane that every graphics product has to follow the route of Canvas (remember the simplicity of Canvas 3 and the horror of what followed?) and Freehand that sucked soccer balls from the very beginning
here's a simple test: how many of Photoshop and Illustator users enjoyed drawing/adding arrows? Such a simple thing but guess what - nothing is simple anymore...
I've spent few years doing some experimental stuff related to cloning in a major academic research intstitution on the east coast. Dolly's life from cloning to premature departure from this to a better world is a remarkable event in the history of biological science. HEre is why: it took about 100 years to progress from 1869 Miescher's (sp?) description of nucleoprotein in pus cells to the Watson-Crick model of DNA. Since early 1960's the effort was to describe how the genetic information is tranformed into something that can be used to build cells, tissues, organs - RNA transcription, protein translation and biochemical machinery that does it. By today we have a pretty good general undertanding of how that stuff works but many important details are missing as yet.
Cloning attempts are old by now (~70 years). From the very onset, the idea was to examine the mechanism of functional specialization of cells. Theoretically cells can either lose some DNA to achieve this goal or do something else. Cloning shows that at least some cells that can produce clones retain the whole developmental program from the embryo to a fertile adult. And considering the success of cloning of many mammals from various cell types, it is pretty safe to conclude that likely it is epigenetic modifications (non-genetic but stable modifications that can be propagated even when DNA is replicated) of the genome, such as DNA methylation, that are involved in cell specialization. Telomere length is another important consideration for both cloning and cancer biology.
So what's the point you may ask by now?
Here it is: Cloning of farm animals is only a smaller element of a bigger picture. You have to look beyond this.
Success of cloning of Dolly and many other cloned animals demonstrated that early ideas of being able to design chemical drugs and biologicals that could affect development are reasonable. Death of Dolly, low efficiency of cloning, abnormalities of clones are the signs of a very complicated and as yet poorly understood mechanisms of epigenetic control and reprogramming of the genome (yes, reprogramming!) during normal development after fertilization and after nuclear transfer in cloning experiments.
The whole media frenzy, right wing's negative reaction and idiotic claims of various docs, clans and biotechs is the reflection of a great scientific process that takes place in a number of labs around the world. There is a lot to learn and whatever we find - it will be really cool because the Nature designed it and beta-tested it for a long-long time. Likely winners of this search will be recipients of stem cell-based therapies, tissue degenerative disorders and cancer patients.
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you are right on the money anon coward it is simplu insane that every graphics product has to follow the route of Canvas (remember the simplicity of Canvas 3 and the horror of what followed?) and Freehand that sucked soccer balls from the very beginning here's a simple test: how many of Photoshop and Illustator users enjoyed drawing/adding arrows? Such a simple thing but guess what - nothing is simple anymore...
silly you - do you think they would bother asking Kasakhs' or Turkmens' opinion - you obv spent your life in the civilized world
no offence but all you wrote is total bs - you have no idea how far from reality you are...
I've spent few years doing some experimental stuff related to cloning in a major academic research intstitution on the east coast. Dolly's life from cloning to premature departure from this to a better world is a remarkable event in the history of biological science. HEre is why: it took about 100 years to progress from 1869 Miescher's (sp?) description of nucleoprotein in pus cells to the Watson-Crick model of DNA. Since early 1960's the effort was to describe how the genetic information is tranformed into something that can be used to build cells, tissues, organs - RNA transcription, protein translation and biochemical machinery that does it. By today we have a pretty good general undertanding of how that stuff works but many important details are missing as yet. Cloning attempts are old by now (~70 years). From the very onset, the idea was to examine the mechanism of functional specialization of cells. Theoretically cells can either lose some DNA to achieve this goal or do something else. Cloning shows that at least some cells that can produce clones retain the whole developmental program from the embryo to a fertile adult. And considering the success of cloning of many mammals from various cell types, it is pretty safe to conclude that likely it is epigenetic modifications (non-genetic but stable modifications that can be propagated even when DNA is replicated) of the genome, such as DNA methylation, that are involved in cell specialization. Telomere length is another important consideration for both cloning and cancer biology. So what's the point you may ask by now? Here it is: Cloning of farm animals is only a smaller element of a bigger picture. You have to look beyond this. Success of cloning of Dolly and many other cloned animals demonstrated that early ideas of being able to design chemical drugs and biologicals that could affect development are reasonable. Death of Dolly, low efficiency of cloning, abnormalities of clones are the signs of a very complicated and as yet poorly understood mechanisms of epigenetic control and reprogramming of the genome (yes, reprogramming!) during normal development after fertilization and after nuclear transfer in cloning experiments. The whole media frenzy, right wing's negative reaction and idiotic claims of various docs, clans and biotechs is the reflection of a great scientific process that takes place in a number of labs around the world. There is a lot to learn and whatever we find - it will be really cool because the Nature designed it and beta-tested it for a long-long time. Likely winners of this search will be recipients of stem cell-based therapies, tissue degenerative disorders and cancer patients.