Livers are a smart choice because they're relatively simple - for an organ anyway. The overall structure isn't important, just the hepatocytes, a bunch of immune cells and lots of blood vessels.
Also given the propensity for humans to trash their livers doing at-home toxicity testing (alcohol is the number one reason for liver transplants, acetaminophen is number 2) there is a huuuge market for replacements. Very clever for a startup.
Actually, it's hardly that simple. While you espouse a perfectly reasonable plan, there are lots of things that can get in your way. That job that concentrates on happiness (whatever that is) just laid you off. You run through your savings in 9 months looking for another job. Then your wife comes down with breast cancer.
I see this stuff all of the time. It's not just American Hedonism that is going to screw the Millenials - it's hedonism, no safety net and an economy run by those nice people that brought you 2008. If you're of the Buddhist persuasion then you can sigh, work some more on your karma and hope next time you get reincarnated as a housefly. The rest of us just get depressed.
No, it doesn't. It's a popular meme around here but completely untrue. In jail, they will offer you some base level of care for serious problems but prison officials get to determine how serious it is and if it gets treated. Jail providers tend not to be on the right side of the bell curve, so even if you get to see the doc or midlevel, you may end wishing you hadn't.
If you need to be treated for a psychiatric illness, your choice of medicine will be significantly limited since many of those drugs can make you feel good (and thus have a marketable value in jail and are heavily restricted. If you hurt, well, too fucking bad. You get a tylenol or, if you're very lucky a tylenol and an ibuprofen.
The major downside of going to the ER for care is that the guy next to you might be strapped down to the gurney and being rather vocal about it. He's the one that got the bill from the last time he was in the ER.
The little problem with your take on this adolescent fantasy is the that Appleton (a nom de plume if IRC) never envisioned that 'ol Tom would own the airship. And the bank. And the town. And most of the state.
North Slope of Alaska. Siberia. Anyplace in the enormous expanse of the boreal forest / not-so-permafrost and targa regions that encircles the planet.
Roads are becoming a big issue with global warming (which, of course isn't happening except in the arctic and nearby regions). Even a month less of ice road makes a number of projects economically infeasible because helicopters and bulldozers don't get along all that well.
Of course, we are talking about things that are on the edge of possible, much less not actually existing at present. But the market is probably there if you can deliver.
If you think you are going to mitigate the effects of the current anthogenic forced warming by consuming less, you are going to be a sad panda.
Governments might tolerate cost shifting, tax increases or other economic versions of rearranging the deck chairs, but slowing growth isn't going to fly. To the first approximation, the entire world economy is based on increase. Even stasis is bad.
Since a constant increase is an exponential function, we've got a bit of a problem as exponential functions tend not to be long lived natural phenomena. There is a reason that economics is called the 'dismal science'.
Hmm. I sometimes wonder. Nobody I know admits to voting for him. In the deeply Red state of Alaska.
That's not precisely true. The couple of maniacs that run around with their beat up pickups festooned with NRA and Sarah Palin bumper stickers will still admit to it, but no one else.
Pretty much this. Cardiovascular risk is one of the best studied disease states known. Which is probably why they studied it. Even then, the 'AI' algorithms only improved risk stratification around 5% - nothing to sneeze at but hardly earth shattering.
OK, now, for extra credit lets risk stratify middle age hypertensive diabetics who are depressed.
Like the typical 'real world' patient. I'd just love some help here but the underlying data just doesn't support it. Which is kinda surprising since we've been studying these folks for a while. Simple medical problems are simple. Typical medical problems are not.
Nope. In the early 21st century, ICBMs are a solved problem. Especially when you're using surplus Russian gear. Simple, cheap. More or less effective.
Hell, in the US a single businessman can build modern ICBMs from scratch.
The warheads are a bit more of a problem, but again, it's not like a whole bunch of other people haven't been able to make them. Pakistan is not exactly on the list of Big Deals in the world.
Stop Assad? Really. He messed a (largely Russian) airfield. Yes, Orange Fluff has sent a message but it remains to be seen how well Assad has been listening - it's only been a week.
The ONLY deterrent that NK needs - and already has - is massed artillery within range to hit the SK capital in minutes. The only thing that would take out the vast majority of those weapons would be a nuke - right outside the largest city in the country which houses half the population of the country. Oops.
Sure, you can blow NK into tiny little bits, but then you're going to take enormous civilian casualties. Perhaps historians can justify this 100 years hence but not even the Orange Fluff is psychopathic enough to give that particular order.
If they want to wait several million more years for the southern part of the Pacific plate to wander over somewhere in the general vicinity of NK;
The North Korean navy is considered a brown water navy and operates mainly within the 50 kilometer exclusion zone. The fleet consists of east and west coast squadrons, which cannot support each other in the event of war with South Korea. The limited range of most of the vessels means that, even in peacetime, it is virtually impossible for a ship on one coast to visit the other coast.
There is a lot of regulation in the medical device field. Perhaps more than anything short of commercial aircraft. The problem is that the FDA isn't aggressively pursuing being a regulatory agency. If you don't enforce the regulations, following them becomes less of a priority.
The FDA has been criticized by many for being too lax. Various FDA staffers have criticized Congress for cutting funding (ooh, bad government, no biscuit). Truth is probably somewhere in between - there are likely lots of villains.
Slashdot Mirror
Livers are a smart choice because they're relatively simple - for an organ anyway. The overall structure isn't important, just the hepatocytes, a bunch of immune cells and lots of blood vessels.
Also given the propensity for humans to trash their livers doing at-home toxicity testing (alcohol is the number one reason for liver transplants, acetaminophen is number 2) there is a huuuge market for replacements. Very clever for a startup.
Oh, so you're the one who voted for Trump.
Actually, it's hardly that simple. While you espouse a perfectly reasonable plan, there are lots of things that can get in your way. That job that concentrates on happiness (whatever that is) just laid you off. You run through your savings in 9 months looking for another job. Then your wife comes down with breast cancer.
I see this stuff all of the time. It's not just American Hedonism that is going to screw the Millenials - it's hedonism, no safety net and an economy run by those nice people that brought you 2008. If you're of the Buddhist persuasion then you can sigh, work some more on your karma and hope next time you get reincarnated as a housefly. The rest of us just get depressed.
No, it doesn't. It's a popular meme around here but completely untrue. In jail, they will offer you some base level of care for serious problems but prison officials get to determine how serious it is and if it gets treated. Jail providers tend not to be on the right side of the bell curve, so even if you get to see the doc or midlevel, you may end wishing you hadn't.
If you need to be treated for a psychiatric illness, your choice of medicine will be significantly limited since many of those drugs can make you feel good (and thus have a marketable value in jail and are heavily restricted. If you hurt, well, too fucking bad. You get a tylenol or, if you're very lucky a tylenol and an ibuprofen.
The major downside of going to the ER for care is that the guy next to you might be strapped down to the gurney and being rather vocal about it. He's the one that got the bill from the last time he was in the ER.
The little problem with your take on this adolescent fantasy is the that Appleton (a nom de plume if IRC) never envisioned that 'ol Tom would own the airship. And the bank. And the town. And most of the state.
Appleton was kinda funny that way.
Slow motion is the best motion.
North Slope of Alaska. Siberia. Anyplace in the enormous expanse of the boreal forest / not-so-permafrost and targa regions that encircles the planet.
Roads are becoming a big issue with global warming (which, of course isn't happening except in the arctic and nearby regions). Even a month less of ice road makes a number of projects economically infeasible because helicopters and bulldozers don't get along all that well.
Of course, we are talking about things that are on the edge of possible, much less not actually existing at present. But the market is probably there if you can deliver.
And then, there is always Amazon.
I know! We can engineer more persistent symbiotic algae. I sure we can find a 'mother-in-law' gene somewhere and slice it in.
Whatcouldpossiblygowrong?
If you think you are going to mitigate the effects of the current anthogenic forced warming by consuming less, you are going to be a sad panda.
Governments might tolerate cost shifting, tax increases or other economic versions of rearranging the deck chairs, but slowing growth isn't going to fly. To the first approximation, the entire world economy is based on increase. Even stasis is bad.
Since a constant increase is an exponential function, we've got a bit of a problem as exponential functions tend not to be long lived natural phenomena. There is a reason that economics is called the 'dismal science'.
Mentally ill? You represent thousands of distinct personalities, Mr. or Ms. AC, and you call us mentally ill?
Or were you talking to yourself again?
This is what everybody wanted right? right!?
Hmm. I sometimes wonder. Nobody I know admits to voting for him. In the deeply Red state of Alaska.
That's not precisely true. The couple of maniacs that run around with their beat up pickups festooned with NRA and Sarah Palin bumper stickers will still admit to it, but no one else.
I wonder what happened?
Rooting would imply that you were taking over it's function. This is more like overclocking.
kale juice, all the way
All the way where?
Not to worry. I still get American Girl adverts after buying one for my niece. Who just graduated college.
I still get Hello Kitty adverts after buying some USB drives as a joke.
Whatever the hell info they have on me, well, good luck with that.
Russians don't do tentacle porn. That's Japanese.
Nope. Google is your friend.
Trust the computer.
Pretty much this. Cardiovascular risk is one of the best studied disease states known. Which is probably why they studied it. Even then, the 'AI' algorithms only improved risk stratification around 5% - nothing to sneeze at but hardly earth shattering.
OK, now, for extra credit lets risk stratify middle age hypertensive diabetics who are depressed.
Like the typical 'real world' patient. I'd just love some help here but the underlying data just doesn't support it. Which is kinda surprising since we've been studying these folks for a while. Simple medical problems are simple. Typical medical problems are not.
What would Trump do if Kim did take out Anchorage?
Don't know what Trump will do (probably first have to look it up on a map), but the rest of Alaska would rejoice.
A wretched hive of scum and villainy.
Nope. In the early 21st century, ICBMs are a solved problem. Especially when you're using surplus Russian gear. Simple, cheap. More or less effective.
Hell, in the US a single businessman can build modern ICBMs from scratch.
The warheads are a bit more of a problem, but again, it's not like a whole bunch of other people haven't been able to make them. Pakistan is not exactly on the list of Big Deals in the world.
Ow! My balls!
Stop Assad? Really. He messed a (largely Russian) airfield. Yes, Orange Fluff has sent a message but it remains to be seen how well Assad has been listening - it's only been a week.
Woo hoo. Big man.
Uh... That's the Daily Mail. And Vice.
Maybe stick to well, journalism?
The ONLY deterrent that NK needs - and already has - is massed artillery within range to hit the SK capital in minutes. The only thing that would take out the vast majority of those weapons would be a nuke - right outside the largest city in the country which houses half the population of the country. Oops.
Sure, you can blow NK into tiny little bits, but then you're going to take enormous civilian casualties. Perhaps historians can justify this 100 years hence but not even the Orange Fluff is psychopathic enough to give that particular order.
If they want to wait several million more years for the southern part of the Pacific plate to wander over somewhere in the general vicinity of NK;
The North Korean navy is considered a brown water navy and operates mainly within the 50 kilometer exclusion zone. The fleet consists of east and west coast squadrons, which cannot support each other in the event of war with South Korea. The limited range of most of the vessels means that, even in peacetime, it is virtually impossible for a ship on one coast to visit the other coast.
https://en.wikipedia.org/wiki/...
But then they'd only get to annoy Mexico.
There is a lot of regulation in the medical device field. Perhaps more than anything short of commercial aircraft. The problem is that the FDA isn't aggressively pursuing being a regulatory agency. If you don't enforce the regulations, following them becomes less of a priority.
The FDA has been criticized by many for being too lax. Various FDA staffers have criticized Congress for cutting funding (ooh, bad government, no biscuit). Truth is probably somewhere in between - there are likely lots of villains.