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Will Genetic Engineering Kill Us?

Kaz Riprock writes "Mark Baard, author of this Wired article was a recent attendee at The Future of Human Nature symposium (that I helped organize). The talks were held at Boston University through the Pardee Center for the Study of the Longer-Range Future. A high profile assemblage of well-known thinkers, such as Steven Pinker, Lee Silver, and Marvin Minsky, were invited to speak at the 3 day conference to examine what 'Human Nature' would be like in 50-200 years. While the article describes a good amount of the 'doom and gloom' which was presented and discussed, it does not quite capture the upside to our potential future aims. One example from the conference was the talk by Christine Peterson, head of The Foresight Institute, on the future use of nanotechnology to better the human condition."

26 of 486 comments (clear)

  1. The answer by Jade+E.+2 · · Score: 5, Funny
    Will Genetic Engineering Kill Us?

    Not if Nanotechnology gets there first.

  2. Alarmist prediction are the enemy of progress by dtolton · · Score: 5, Interesting

    This is the same line of thinking that many people have followed
    for the last century. Every new technology has been heralded
    with predictions of doom and gloom. The 70's and 80's produced
    volumes of work predicting robots subjugating mankind to their
    will. As we progress with work on AI we find we are still a
    long way from that type of outcome.

    The stories are too many to recount all of them, but a quick
    jaunt through history shows that people are resistant to
    change. They are slow to adopt technologies that change their
    world view, and they often react violently if that change will
    alter their religious view of the Universe. As an example look
    at the debate still raging over evolution.

    That isn't to say we shouldn't be careful of new technologies
    and put good safeguards in place, however I for one am tired of
    overly alarmist predictions of every new technology. It would
    be nice to see some beautiful predictions of how the future
    might be better with the technology.

    Maybe with Genetic Engineering we'll be able to eliminate the
    stupid gene. (That statement may set off a
    firestorm.)

    --

    Doug Tolton

    "The destruction of a value which is, will not bring value to that which isn't." -John Galt
    1. Re:Alarmist prediction are the enemy of progress by SocialWorm · · Score: 4, Informative

      Maybe with Genetic Engineering we'll be able to eliminate the stupid gene. (That statement may set off a firestorm.)

      It already did -- James Watson, one of the orgininal discoverers of DNA, said what basically boils down to exactly that earlier this year, and it was quite controversial. See http://www.newscientist.com/news/news.jsp?id=ns999 93451

      --
      My Blog: http://nic.dreamhost.com/
    2. Re:Alarmist prediction are the enemy of progress by ElectricRook · · Score: 5, Insightful
      Doug,

      Excellent observation, I agree.


      But you are missing the intention of this alarmism. The intent is to sell. It's a sales event for books, seminars, etc.
      There are three things that get peoples attention: sex; novelty; and fear. The market for sex is pretty much cornered. That novelty thing takes thought, and can die quickly. But that whole fear thing... Man that stuff can be sold, mixed and resold time and again.


      By the way, is that Stupid Gene a double recessive?

      --
      - High Tech workers, please say NO to Union Carpenters, their Union sees fit to control our compensation.
    3. Re:Alarmist prediction are the enemy of progress by Anonymous Coward · · Score: 4, Interesting

      I will be little heretic, but i think genetic enineering is the ONLY thing which can SAVE US. Natural selection does not work anymore (at least in "civilised" world) thanks to progress in medicine. Even sexual selection does not work - in its second-reproduction phase: succesful peopple (whatever does it mean) have usualy less children than the ones which somehow left over to each other. So the the degeneration in western countries is slowly progressing during last 100 years. If the mankind does not want to give up its humanitarian ideas and make artificial selection (sterilisation or even worse...), genetic engineering is the only hope.

    4. Re:Alarmist prediction are the enemy of progress by JDevers · · Score: 4, Interesting

      Did you and I read different things?? But in a documentary series to be screened in the UK on Channel 4, Watson says that low intelligence is an inherited disorder and that molecular biologists have a duty to devise gene therapies or screening tests to tackle stupidity. "If you are really stupid, I would call that a disease," says Watson, now president of the Cold Spring Harbour Laboratory, New York. "The lower 10 per cent who really have difficulty, even in elementary school, what's the cause of it? A lot of people would like to say, 'Well, poverty, things like that.' It probably isn't. So I'd like to get rid of that, to help the lower 10 per cent The lower 10 percent isn't limited to those that are retarded, that would be more like the lower .5 percent. He is basically refering to "common idiots". I happen to agree with him, but just wanted to point out what you didn't notice.

  3. Best argument I've ever heard. by unformed · · Score: 5, Insightful

    When a beaver builds a dam, it's called nature. When man builds a dam, we're destroying nature. Is the purpose of our life not to better our lives? And if so, why should we not be allowed genetic engineering, cloning, going to different planets.

    The world is constantly changing, and we are part of it.

    Now I do understand that many people have moral issues with genetic engineering, and I did (and still somewhat do) too, but if done right, what's the problem. For those don't understand, read Aldous Huxley's Brave New World. It's a scary world that he describes, looking at it from our point of view; however, from the inhabitants point of view, it's a perfect world. Brainwashed, yes, but very few people are unhappy. Furthermore, the few that are too intelligent to live in that world are given their own island, to do as they please.

    A perfect society, but it takes a while and a lot of change to get there.

    1. Re:Best argument I've ever heard. by hey! · · Score: 5, Insightful
      Well, forone thing beavers have built dams the same way for hundreds of thousands, if not millions of years. Changes in scale and method of beaver dams take place on evolutionary time scales. Ecosystems can adapt.


      Changes in human dam building methods and scale happen on cultural time scales (e.g. millions of times faster). We also build dams not for the benefit of ourselves, but of hundreds of thousands or millions of people. Therefore our dams tend do be much larger. You can't compare the local millpond to the Yangtze project.


      Getting to your basic point, perhaps the poing of our lives is to better our lives. However, we, unlike the beaver, are free to consider in advance the consequences of our action, and to define what "better" would be.

      --
      Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
    2. Re:Best argument I've ever heard. by Drakonian · · Score: 4, Interesting
      Whoa whoa whoa. What if a beaver builds a new "superior" beaver? Is that still nature?

      The best argument I've read against genetic engineering goes something liek this. We will have no way to know if the things we excel at are just because of the $99 Gene sale from XYZ Cromosones or if it's because we worked hard and tried to get better at something we like/want to do. Say for example a mother has worked very hard to become a skilled pianist. She wants her child to be even more skilled than her at music, so just gives her the appropriate music genes. Now the daughter is an excellent pianist but is playing the piano something she does because she enjoys music? Or does she just feel this strange compulsion to play the piano without it being something you use strive for? The worst part about it is how can she tell? If you are genetically engineered, how can you have thoughts about whether genetic engineering is OK? Your whole mindframe is biased. How can you find out who you really are, and what isn't just part of a catalogue? How can you control your own destiny when it has already been decided for you?

      I also think you have a very unique perspective on Brave New World. A perfect society!?? Out of interest, did you think 1984 depicted a similarly perfect society? Do you feel that is what society should be like - no real freedoms, everyone just walking around in a state of perpetual bliss? A society where you in no way control your own destiny. I guess in that case, it would make sense that you approve of genetic engineering.

      --
      Random is the New Order.
  4. A kid playing with a handgun by Dark+Bard · · Score: 4, Insightful

    The real problem is the irresponsible way it's being handled. Shortly after the first field tests geneticly enhanced grain is in wide spread use. Now it looks like the insects have become immune to it and the "super weed" senerio has come true. Causually throwing animal genes into plants and plant genes into animals is terrifying. The standards are so lax a generation or two of the plant or animal and it's in the ecosystem. If you look at the effect 200 years of developement has had on the lanscape, what will 200 years of genetic tinkering do to the genetic landscape?

    1. Re:A kid playing with a handgun by Dark+Bard · · Score: 5, Insightful

      The more you learn about cloning the less afraid you become. The downside of cloning is we aren't very good at it and the percentage of birth defects is unacceptable. You are completely wrong about genetic engineering. I have read a great deal about it and went from being a supporter to some one that thinks field studies should be stopped indefinately. Forget the SciFi end of the world senerios. They are possible we just don't need them to be afraid. Genetic engineering is likely to cause in the next century, quite possibly the next ten years, the greatest famines this world has ever seen. Genetic diversity in cereal crops may already be a thing of the past. One desease can wipe out not just a harvest but an entire species of grain. Can't happen? It's going on now with banannas. Everyone is saying the current species being farmed will be extinct in less than ten years due to desease. You can live without them? Well in parts of Africa they are a staple. This is just one problem genetic engineering may casue. They have already made a number of insects immune to the most common form of insectacide. This effects non GM crops. It's been big news lately. There is a lot of potential good that can come from genetic engineering but we have to learn to be responsible. Remember all the nuclear clean up? How do you clean up genetic contamination?

  5. Predicting the future by jeffmock · · Score: 5, Interesting

    This thing reminds me of an interview with Steven Spielberg when the "back to the future" movies came out in the 80's. He said that it's really easy to write about an apocolyptic future, but hard work to imagine a happy world in the future.

    Maybe it's because we tend to idealize the past and forget about the horrible aspects of life 50-200 years ago. Maybe this sets a trend line where the past was great, the present is not as good, so the future must be hellish if we extrapolate far enough.

    jeff

  6. Gen-eng will join species, not divide them. by cookie_cutter · · Score: 4, Interesting
    genetic engineering and other technologies are going to divide human beings into classes that may one day try to destroy one another

    This demonstrates a misunderstanding of the concept of species and of what advanced genetic engineering technologies allow.

    The biological species concept defines a species as a set of organisms which can breed among themselves, but not with members of other species

    Genetic engineering, particularly trangenics, makes this concept obselete, because it is possible to transfer genes from any species to any other, pretty much eliminating any species boundaries.

    Yes, different people will have different sets of genes, but with gen-eng, it will be possible to move from any one type to any other, ie "upward mobility" will be possible for everyone, which is infinitely preferable to what we have now where people are stuck with the gene's they're born with.

    1. Re:Gen-eng will join species, not divide them. by Nerant · · Score: 4, Insightful

      What truly scares me, is the possibility of only the rich being able to afford genetic "enhancements".
      Imagine a world where if you want your child to benefit from genetics, you have to spend a proportional amount of money for said engineering to be done.
      The social divisions between the rich and the rest of us, will only widen.
      Perhaps genetic enhancements should be regulated as a public benefit or utility, where all have somewhat equal opportunity to get them.

      --
      Be kind. There are too many mean people out there already.
  7. There are counterarguments, of course by joak · · Score: 4, Insightful

    "We might create a group of people much smarter than us, that might want to kill us," said bioethicist George Annas, chair of the Health Law Department of Boston University School of Public Health.

    Or they might be so much smarter than us that they realize they don't need to kill everyone who differs from them . . .

    (Comment borrowed from Sladek's "Roderick at Random")

  8. good analysis by ih8apple · · Score: 4, Informative

    Here's a good analysis on eugenics from salon.com from 3+ years ago.

    Good information, but also important is the fact that things haven't changed much in the last 3 years in spite of everyone's fear of things moving too fast for the ethical consequences to be considered.

  9. Stephen Hawking's view of the future... by jbischof · · Score: 4, Interesting
    ..which I find very appealing at least, if not also completely agree with.

    In one of his lectures he talks about the future of our society, especially that related to genetic engineering and how the future of science will effect our evolution.

    Evolution up to know, has proceeded slowly, about one bit of DNA changes every year. If we take it into our own hands (ignoring the moral implications and side effects) we could alter our own DNA at a far greater rate. Add that with the ability to predict what the changes will do, we can evolve at a far greater rate.

    Our children will be better, faster, and stronger. I mean who initially would say no to "Sir, would you like me to remove the possibility of Downs Syndrome from your child"? Now replace Downs Syndrome with Diabetes or with Weak Minded or with Scrawny. You can see that it isn't that unreasonable or that far away.

    Of course, when you put yourself in Stephen Hawking's shoes, a man who biology abandoned a long time ago, it makes perfect sense to imagine that intelligent humans can prevent the types of conditions that completely disable a person without the aid of a machine.

    1. Re:Stephen Hawking's view of the future... by Razor+Blades+are+Not · · Score: 5, Insightful

      But as the article points out - our genetic structure isn't a clear roadmap to these kind of traits.
      There isn't a "smarts" gene in the same way there isn't a "grandmother" neuron.

      You are correct: given the option to remove, without fear of mishap, genetic dispositions towards certain undesirable traits, most people would choose to do so.
      But we are a very long way of being able to promise that. If instead you asked a parent
      "Would you like a small chance your child might be more intelligent and healthier, but with a large risk that it may be paralyzed from the waist down from birth?"
      Most people would say no.

      That's not to say that the day may not approach when we can sequence ourselves a better life, but until then, some forethought is required.
      Using ethical means of consideration is only good sense.

  10. Better Programmers by Herkum01 · · Score: 4, Funny

    I know this is will become true, how can we current batch of programmers can compete with programmers of the future with thier third arm. They will be able to keep both hands on the keyboard AND STILL USE A MOUSE!

  11. No it will save us by quantaman · · Score: 4, Insightful

    Currently the human race is on the path to extinction (or at least significant degredation). The fact is that large numbers of people with genetic mutations and just plain bag genes that would of been eliminated from the gene pool are now living and reproducing. When it comes to the longterm survival of the species we really only have a few alternatives.

    1. Eugenics. Not a choice we want to take forced sterilization has been tried in the past (the Canadian government for a while in the 40s or 50s (i think) had the forced sterilization of people with mental disabilities) and this would constitute quite a serious breach of a persons rights and could start us down a slippery slope. Another option is screening of fetus' while this may work for serious disabilites i don't really see it pratical trying to work out whether the fetus is productive enough to keep, this is also difficult to execute while avoiding the species degrading as you would have to reject fetus' who are just a little stupid or destined to have other minor problems otherwise you're just avoiding the inevitable.

    2. No more medicine or at least careful application of it. Only treat those ill by accident, not by genetic weaknesses, not a nice alternative either.

    3. Selective breeding. Been doing this for a few thousand years (with livestock). Not sure to what extent it was practiced with ancient slaves but selective breeding is certainly a reason why the US has so many great black athlete's currently. This would be hard to enforce and again would constitute major violations of human rights. Again not an option I'd choose.

    4. Do nothing. Simple enough we keep improving health care and ignore the genes. Eventually either the situation gets so bad we have to take an alternative or the race is degraded to a point where it can't sustain its society and we either collapse destroying ourselves entirely or fal back to a point where evolution takes over again until we get to that point again. Rinse and repeat. Not fun either.

    5. Genetic therapy. Start with fixing obvious defects but slowly build up to actual improvements. Depending on implementation we quickly reach a point where the rich form a true nobility, in other words if your parents are rich you actually are faster, smarter, stronger, and more stable (as long as you don't get too arrogant). One solution to this is strict controls on the amount of genetic engineering like with a public health care system. Everybody gets free access to the same treatment regardless of wealth or status and everybody wins. Social stability remains and the race keeps improving. Sounds like the best option to me.

    p.s. can anybody think of any options I missed?

    --
    I stole this Sig
  12. As someone with a LOT to gain... by gurps_npc · · Score: 5, Insightful
    First of all, let me explain, that this is my life we are talking about.

    I have an overactive immune system that attacks my own kidneys. It could kill me in about 10 years. (I am in my 30's).

    Kidney transplants from family/etc. might help, but the real problem is that my immune system attacks my OWN kidneys, so you see the problem. Immunosupressant drugs are dangerous, leave me open to disease, and are not 100% effective. I end up with a weak immune system that still damages my kidneys a little bit.

    The best hope for saving my life is genetic research into cloning kidneys from my own body, and then implanting healthier, younger kidneys into me. This is barely within our technological grasp, if we make it a priority. Dolly made you wonder, but it gave me hope.

    That said, I do not consider Genetic manipulation of Human beings to be changing the species.

    First of all, evolution is VERY effective. Any changes we make will be relatively minor. Our only real advantage over Evolution is speed.

    Instead of NEW species, we will be making new "races" as in black vs. white, etc. etc.

    It will take hundreds of years of actual evolution (living on seperate planets) to differentiate us enough to declare the new races new species.s

    But we will end with a more vaired set of intelligent human races.

    --
    excitingthingstodo.blogspot.com
  13. Re:Aside from no X-Men.. by k-0s · · Score: 4, Insightful

    I see your point but this will most likely be the sole domain of first world countries. Will the population bump up? Very minimally if at all. First world countries are on the verge of ZPG (zero population growth) as it is right now. Saving one child out of 100 or 1000 is not going to make any kind of population spike. The over population is happening in third world or low end second world countries where this technology will propbably not make it to and if it does make it there the cost is going to be out of range of the people there. This is all very sad but the truth is sad. I really don't see overpopulation being the major problem with the technology.

  14. Cro-Magnon Clans Urged to Go Slow With Fire by reallocate · · Score: 4, Funny

    (Cro-Magnon News Agency) -- Shamans and clan activists are questioning the wisdom of allowing widespread use of newly discovered techniques for artificially producing fire.

    A Chauvet-Pont-d'Arc meeting, sponsored by Clans United for Ethical Technology, today issued a resolution calling on clan and tribal leaders to block the spread of fire-making techniques to the general population.

    "We must insure that making fire remains under the strict control of shamans and our clan leaders," said Clans United chief, Orm Marr-dhuk. "Tests have indicated that fire is dangerous if not handled properly. We fear that its widespread use could result in countless deaths by burning and the loss of many of the forests on which we all depend for shelter and food. Pending new developments, Clans United urges our leaders to decree that fire making will remain the exclusive privilege of the shaman and leadership classes. Perhaps someday, if the common people have developed the skills to use fire without risking life and limb, we can reconsider our recommendation."

    When asked about the several flaming tar torches that provided light for the meeting at the Cauvet cave, Chief Orm replied that "We shamans have made the appropriate sacrifices to the goddess. She has given us the secrets of safe fire use. We cannot expect ordinary people to understand these things."

    --
    -- Slashdot: When Public Access TV Says "No"
  15. At a crossroads by Master+Switch · · Score: 4, Insightful

    I think Humans are reaching a crossroads that every intelligent species in this universe reaches at some point in its history. We are coming to understand the machinery of life and how we ourselves our put together. We now have or will soon posses the knowledge we will need to tweak and adjust human behavior by altering the way our minds form. We will be able to tweak and "improve" our bodies (Or the bodies of subsequent generations). This doesn't mean that our generation or even two or three generations out will be able to do these things, but that in the next 1000 years or so, we will see dramatic self directed changes in our form and function.

    Having said that, I don't believe that this will lead to a panacea. There in lies the test, can we survive and thrive under our own evolutionary direction. Our behaviors to date were evolved to help us thrive in somewhat different circumstances. Do we have the foresight to guide our own evolution, can we overcome our shortcomings and make the right decisions. I think the difference will be in how well we temper our aggressive, violent nature. If we can balance aggression with forethought, we might just make it. I'm sure that the universe is littered with failed species that have gotten this far and then imploded. Let us hope we do not become one of them.

    --
    -Master Switch, one more element in the machine
  16. Spam of the future... by Johnboi+Waltune · · Score: 4, Funny
    Knock down walls with your genetically-engineered MONSTER COCK!!

    I personally hope the world is turned to gray goo by nanotech before I ever see that in my inbox.

    --
    "The advanced societies of the future will be driven by competing systems of psychopathology." -JG Ballard
  17. Wanna bet? by dubl-u · · Score: 4, Interesting
    As many people saw in Wired, there's already a prediction on this over at Long Bets:
    By 2020, bioterror or bioerror will lead to one million casualties in a single event.
    The scary part is that in the year the prediction has been up, nobody has been willing to bet against him.
    For those not familiar with the site, it's a place where people can make predictions and bets about the future. The soonest allowable bet is two years from now, but most go out a lot farther than that. So if you're so sure about your opinions on biotech (or any other topic) that you're willing to throw down on the public record, you can. (All the wagers go to charity, so don't think you'll be getting rich. But if you win, you can pick the charity.)