Jocks v. Nerds: Detecting Gene-Dopers
kevinvee writes "The World Anti-Doping Agency will soon put into place gene doping tests to detect athletes using gene therapy. Perhaps the most important part to recognize is that Congress delegates have said that gene doping is a 'clear and present danger.' Professor Geoff Goldspink mentions this of gene therapy: 'We can put genes into mice and create Arnold Schwarzenegger mice.' So, be sure to watch next year's elections for furry white mice."
According to the human genome project information page, gene therapy is still in a very experimental state, and it could potentially be very dangerous for atheletes to engage in.
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CF is a disease that could be perfectly treated by gene therapy... it comes from a single defect, though the defect itself can vary, in the cell membrane Chloride channel. Treat the defect, and you can avoid all the consequences of CF (pneumonia, pancreatitis, sterility, Pseudomonas colonization, etc). CF is one of the most common genetic diseases, and is THE most common lethal genetic defect among caucasians.
For the non-medical, non-bio-science geeks, Here's some info courtesy of the NIH. Much like genetic counseling for various hemoglobinopathies, an argument can be made for the same approach here, particularly since some estimates put the CF gene prevalance at 5% in the white/northern european population.
Curiously, there's speculation as to how that gene became so prevalant... it appears to be protective against Cholera, and perhaps some other diarrheal illnesses. Additionally, it may also offer some resistance against Typhoid. The theory has been advanced that partial resistance among heterozygotes provided a genetic advantage during the plagues of humanity's past, which included Typhoid and Cholera.
KFG: I've taken care of many CF patients... Do you mind terribly if I ask your approximate age?
Even if a man chops off your hand with a sword, you still have two nice, sharp bones to stick in his eyes.