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U.S. Continues Biological Warfare Research

merryprankster writes "Researchers at Saint Louis University have engineered a strain of mouse-pox virus which kills 100% of animals it infects - even when the mice have been treated with vaccination and anti-virals. The deadliness of the virus is related to the addition of a protein IL-4 which shuts down cell-mediated immune response. The engineered virus is not contagious and does not affect humans but the research has drawn some condemnation as being dangerous and unnecessary."

29 of 945 comments (clear)

  1. Seriously... by Evil+Adrian · · Score: 5, Insightful

    Seriously, what is the point of engineering something like this?

    If it was another country's research team we'd probably be invading by now...

    --
    evil adrian
    1. Re:Seriously... by 99bottles · · Score: 3, Insightful

      The article notes, "He says his work is necessary to explore what bioterrorists might do."

      If research was stopped everytime someone asked "why?", there wouldn't be much done at all.

    2. Re:Seriously... by s20451 · · Score: 4, Insightful

      The point of researching these things is to not get caught with your pants down when someone else invents it. Now that this strain of smallpox has been developed, the scientists can determine how to protect against it.

      Examining one scientific study or result out of context usually misses the point of the overall body of research. For example, several congressmen have been campaigning against studies into sexual deviancy that have been funded with federal money. However, these studies are critical to understanding how diseases like HIV spread.

      --
      Toronto-area transit rider? Rate your ride.
    3. Re:Seriously... by ComaVN · · Score: 3, Insightful

      I'm pretty sure Syria would not be allowed by the US to perform this kind of research, not even for "defensive" reasons.

      --
      Be wary of any facts that confirm your opinion.
    4. Re:Seriously... by nukeade · · Score: 3, Insightful

      Agreed! When the British banned civilian explosives research, it did nothing but make sure the Germans could be extra devastating when the war rolled around. As evil as the research sounds, they are being open and therefore hopefully responsible about it. This could lead to a breakthrough new treatment that would defend us against the new, evil bioweapons that some are developing elsewhere (North Korea).

      ~Ben

    5. Re:Seriously... by nizo · · Score: 5, Insightful
      ... wretched little (introduced) animal called the cane toad. If a virus like this could be engineered such that it would kill them all out, I'd say it's not such a bad thing.


      Actually, the reason you have cane toads in the first place is they were introduced to combat the cane grub. In the end however they seem to be great for killing just about everything except the cane grub. The moral of the story? While we may have good intentions when introducing something new to an environment to control a pest, we may also be introducing new, even worse problems unintentionally. Are you sure you would want a man-made virus that is capable of wiping out an entire species introduced into your country?

    6. Re:Seriously... by M1FCJ · · Score: 4, Insightful
      How do you know you are the good guys? Most of the third world sees America as a bully, invading/bombing countries at will. In their view, America cannot be good.

      Righteousness is relative and in this age no one can argue in favour of "Might is the right".

      I see USA's view of "Although I can do these things freely, you can't" as a hypocrisy.

    7. Re:Seriously... by Sgt_Jake · · Score: 3, Insightful

      You missed the part that I think is probably the most important - by learning how many ways you can manipulate the genes and what effects they produce, you're far more capable of coming up with vaccines and treatments that will combat full ranges of variations. In which case, when some nut bag releases a doomsday virus they won't have to waste nearly as much time trying to narrow down exactly how THIS germ behaves, they can tweak a class of inoculations to combat the majority of the outbreak.

      Short answer, you're right. It sucks but it's necessary.

    8. Re:Seriously... by Asha2004 · · Score: 3, Insightful

      That is absolutely a matter of perspective. Thinking in terms of good and bad (evil) is one of the reasons the US is not loved in a lot of countries. It just isnt that simple. Being right or wrong is not an absolute value, but an interpretation based on the available information and an emotional state. Your "falacious path of moral relativism" is preferable to closing your eyes to other reasonable opinions and perspectives.

    9. Re:Seriously... by BigBadDude · · Score: 3, Insightful


      Thats the most STUPID SHIT i have read omn slashdot [today]....

      Lets "introduce" the virus to the cane toad. Dont you people never learn?

      So why did you guys "introduced" the toads in the first place??

    10. Re:Seriously... by Xaoswolf · · Score: 4, Insightful
      After all the US has never used WMDs have they...

      The US, used two bombs that ended world war two.

      They could have dropped those two bombs, or they could have dropped a thousand normal bombs and had the same result in body count, but not a japanese surrender.

    11. Re:Seriously... by shibbie · · Score: 3, Insightful

      1) No. The US can't find the weapons, now it is looking for war justification on the grounds of research into WMD by Iraq. Also you can bet if the US wanted it, the research could easily be converted into a weapon. Hence "military research".

      2)Tut tut tut. You should have a good look at Amnesty International's site. You have a common misconception there. The US sprayed its own soldiers in Vietnam with toxic chemicals because it didn't want to tell them to move out and risk losing land. Those chemicals had no effect in the short term but became fatal, debilitating and caused serious birth defects.

      Bush is an oaf. This is not a misconception when the majority of the free thinking world knows it. Almost everything he says or does lacks thought and with regards to the enemy labels them as "These bad guys". America is a fine country, but you "guys" seriously need to think about whether you want such an idiot controlling your WMD.

    12. Re:Seriously... by workindev · · Score: 4, Insightful

      Righteousness is relative

      While I'm sure Hitler thought he was doing the right thing by killing 6,000,000 Jews, it doesn't change the fact that it was just plain wrong.

      There always has to be a universal moral ground to fall back on. And killing 6,000,000 people just because you don't like them, or hijacking commercial airliners and crashing them into civilian buildings is universally wrong, despite the fact that the perpetrators thought they were right.

    13. Re:Seriously... by canajin56 · · Score: 4, Insightful

      Why would the US turn on Israel? The only reason there arn't three to four times as many UN sanctions on Israel is that the US has vetoed every single one they could, ever. And where do you think Israel gets its tanks, its combat bulldozers, its planes, its missiles, and NBC weapons, its submarine launched nuclear missiles? The US and British and Australian peace protesters are getting shot, and crushed to death by guns and bulldozers built in the good old US of A. The US. Of course, that's where ALL the current "bad guys" got them, but oh well...So far the US has given Israel $87 BILLION in foreign aid. It comes up to $150 billon if you factor in the interest payments on that money. Think about that. With the power grid in ruins, highways crumbling, schools crumbling, hospitals closing, maybe the US could have used that many billion dollars? What does a country smaller than New Jersey need with that much money? And that figure doesn't even take into account all of the military supplies. Cruise missiles and helicopters and tanks arn't cheap.

      And on the subject of bio-weapons research, the US army has also recreated the Spanish Flu.

      --
      ASCII stupid question, get a stupid ANSI
    14. Re:Seriously... by Luyseyal · · Score: 3, Insightful
      I'm neither an isolationist nor a "let's gut the defense department" kinda person. I'm saying that current policy will lead to a world wide arms race, not deter it. I believe we should be an active partner in the world, not a dominating empire like the Project for a New American Century and its Whitehouse lackeys want it to be.

      -l

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  2. Don't worry... by DrEldarion · · Score: 5, Insightful

    Yeah, don't worry, it doesn't infect humans.

    Er, wait.

    The work has not stopped there. The cowpox virus, which infects a range of animals including humans, has been genetically altered in a similar way.

    Uh-oh.

  3. It's not like viruses ever mutate by colmore · · Score: 4, Insightful

    Don't worry folks, viruses never mutate. There's no chance that a non-contageous virus could become airborne or bloodborne, and there's absolutely no way it could start affecting people. The fact that the US military has created a vaccine proof superbug with a 100% kill rate shouldn't bother anyone.

    --
    In Capitalist America, bank robs you!
  4. Viruses are not always bad... by Animaniac · · Score: 5, Insightful

    The deadliness of the virus is related to the addition of a protein IL-4 which shuts down cell-mediated immune response.

    Wow, just wow! I can't believe people don't realize how useful this is, and how off base the news poster really is. It was not developed to become a means to kill people. Being able to deactivate the entire immune system with a virus is such a huge leap forward. Now we can see how various biological processes work in the absence of the immune system. We have never been able to supress the immune system on this level. We can learn what functions definately need the immune system, gain new insight into autoimmune disease, and so on. Science always advances by altering or eliminating a variable and observing what happens to the others. I'm sure this sounds awfully familiar to all you CS people who spend hours debugging. Next time think before jumping to the OMG DEY R TEH Ev1L!!!11 conclusion.

  5. Who's policing the police? by Marc+Desrochers · · Score: 3, Insightful

    Is it just me, or is the US acting more and more like a rogue nation? Who draws the line, and when?

  6. From the article by Diabolical · · Score: 4, Insightful

    Despite the concerns, work on lethal new pox viruses seems likely to continue in the US. When members of the audience in Geneva questioned the need for such experiments, an American voice in the back boomed out: "Nine-eleven". There were murmurs of agreement.

    What has 9/11 to do with this? Could this virus have prevented the attack? Or any biological/chemical weapon for that matter?

    9/11 has been used as an excuse for too long now to have any real meaning.

    Americans have given up alot of privacy for nothing (as most allready know). The rest of the world has been ordered by the USA to change identification documents or face economical consequences, hand over flight information (including information which has nothing to do with the possibility of being a terrorist), Iraq have been invaded with this as an excuse whil everyone and their mother know right now that there has been no evidence of Iraq being involved with 9/11 and people are still being bombarded with laws and organisations that are supposedly to stop another attack.

    1. Re:From the article by MosesJones · · Score: 3, Insightful


      No no no... 9/11 is the excuse for everything..

      Have a poor economy at home, need to invade... 9/11. Need a "bogeyman" ... 9/11... can't find him well 9/11 another chap.

      The US remains the nation that has deployed WMDs against the most civilians. It remains the nation that refused to sign the chemical and biological non-proliferation treaty.

      9/11 justifies everything. In the same was as Oklahoma didn't justify cracking down on the far-right.

      --
      An Eye for an Eye will make the whole world blind - Gandhi
    2. Re:From the article by Silvers · · Score: 4, Insightful

      I equate this to computer security releases. Would you rather be fully disclosed about a potential security hole or would you rather live in ignorance?

      These kinds of things need to be researched. Mainly because the cost of creating these is becoming lower and lower. Would you rather have no research done on how to protect against these? For those of you thinking the US would actually weaponize this stuff, I suggest a full body tinfoil suit.

  7. Re:wow, not only did you not RTFA... by Atryn · · Score: 4, Insightful
    "The engineered virus is not contagious and does not affect humans"
    Having a spouse working in a microbiology lab with anti-biotic resistance, etc. I would like to point out that VIRUSES MUTATE.

    While I agree that this research has value, lets not underestimate the danger involved. This is why we have containment procedures, etc. What would make me more comfortable with the international treaties on defensive research would be:

    1. Requirement of open communication on research being conducted (not to disclose HOW to do anything, but for awareness of WHAT is being done)
    2. Int'l standards for containment, etc. which could be verified by an int'l body.
    These points allow you to prevent terror-supporting nations from abusing the loophole. If they don't tell us what they are doing and demonstrate observable precautions its illegal.

    Isn't that essentially how the IAEA Additional Protocol treaty works? The IAEA gets to monitor and you fully disclose what you are doing? Iran is signing on to that I believe.
    --
    Come play Moral Decay!
  8. Very, very few Americans understand the facts. by Futurepower(R) · · Score: 5, Insightful

    By some measures, the U.S. government is the most violent that has ever existed in the world.

    The writer of this is an American who is very concerned about his government's participation in violence. In his opinion, a person doesn't really love his or her country unless he or she is willing to look at and understand areas where the country needs improvement. The same principle applies elsewhere. A man doesn't really love his wife if he turns his back when she is having serious, difficult-to-understand problems. And, a person doesn't really love himself or herself unless he or she tries to understand and resolve his or her own inner conflict.

    Strictly speaking, it is the U.S. government that is responsible for the violence, not the people of the United States. Very, very few Americans understand the facts presented here. There are many Americans who support violence, and who angrily reject these facts, but even those probably would not want their money being spent on violence if they fully understood the financial and social impact on their lives.

    The U.S. government has directly killed about 3,000,000 people since the beginning of the Vietnam war. Most of those, an estimated more than 2,000,000, were in Vietnam, a very poor country that did not threaten the United States.

    Historians say that the number of people indirectly killed by the U.S. government is at least another 3,000,000, for a total of 6,000,000. For example, U.S. bombing of Cambodia left that country destabilized, and the forces of violence controlled Cambodia for years after the U.S. bombing.

    The U.S. government has bombed 24 countries in the 58 years since the Second World War. The list below includes only countries bombed, not countries in which the U.S. government was responsible for other violence. The list includes only violence since the Second World War, not the extensive violence before the war. Most U.S. citizens are surprised and skeptical when they see the list, so a few links have been provided to supporting information. For more information, try the Google search engine or see the links below.
    1. Afghanistan, 1998, 2001, 2002, 2003
    2. Bosnia, 1994, 1995
    3. Cambodia, 1969-70
    4. China, 1945-46
    5. Congo (now Zaire), 1964
    6. Cuba, 1959-1961 ("Bay of Pigs" invasion)
    7. El Salvador, 1980s
    8. Grenada, 1983
    9. Guatemala, 1954, 1960, 1967-69
    10. Indonesia, 1958
    11. Iran, 1987
    12. Iraq, 1991-2000, 2003 (The U.S. government used radioactive bombs in the first war against Iraq. See United States War Crimes Against Iraq for what appears to be an accurate history.)
    13. Korea and China, 1950-53 (Korean War)
    14. Kuwait, 1991
    15. Laos, 1964-73
    16. Lebanon, 1983, 1984 (both Lebanese and Syrian targets)
    17. Libya, 1986
    18. Nicaragua, 1980s
    19. Panama, 1989. The U.S. government called it "Operation Just Cause". The link is to a U.S. military web site.
    20. Peru, 1965
    21. Somalia, 1993
    22. Sudan 1998. There are doubts
  9. Failure = Research ? by greenhide · · Score: 4, Insightful

    From the article:

    Ramshaw's team made its initial discovery while developing contraceptive vaccines for sterilising mice and rabbits without killing them. The researchers modified the mousepox virus by adding a gene for a natural immunosuppressant called IL-4, expecting this would boost antibody production.

    Instead, the modified mousepox virus was far more lethal, killing 60 per cent of vaccinated mice. The addition of IL-4 seems to switch off a key part of the immune system called the cell-mediated response.


    Okay. For all of you going on and on about how useful this research for preventing bioterrorism, keep in mind that this is not at all the original intent of the researchers.

    They were trying to make an contagious but non-lethal virus whose sole function was to serve as a contraceptive. Instead, they ended up creating a highly lethal, non contagious virus.

    Granted, it is difficult to know exactly what the effect of mutating or altering viruses will be on the animals they're introduced into, but this is sort of my point.

    If you try modifying a virus to make it non-lethal, and it turns out to be lethal for most of your test subjects, it is not a good idea to to say, "Wow! Let's see what happens when we try that in *another* virus!"

    Since they don't know why the introduction of IL-4 made the viruses non-transferable, they probably don't know enough about this virus modification to assume that other strains won't be contagious when it's introduced.

    --
    Karma: Chevy Kavalierma.
  10. Re:US is the only world power by salesgeek · · Score: 5, Insightful

    I rarely get mad at a post on slashdot. But this one got me going.

    We are now guilty of illegally invading a foreign country without any direct threat of war or attack or in assistance to another country, but simply based on political agenda, public ignorance, public fear mongering, and propoganda about WMD.
    Wow. First, there is no such thing as an illegal war. Frankly, there's hardly such a thing as a civilized war. Who has the athority to say "war is legal" and "war is illegal"? Last I looked on earth the highest authority is a soverign government. There is NO INTERNATIONAL GOVERNEMENT - although some would like there to be one.

    The public was not ignorant about the war in Iraq. I seem to recall almost endless debate over the need for the war. It came to a vote and people with access to even better information than you and I (congress) authorized the president to take action. WMD as justification aside, there were four other pillars to the decision: democratization of the region, oil, terrorism and the plight of the Iraqi people.

    The US is not a world democracy, but a world hypocrisy. We can do it, but NOBODY else can. And there is NOTHING you can do about it.

    Why whould you ever think the US was trying in any way to represent the world? Last I looked only US citizens had the right to vote here. We are not a world democracy. Our government was not founded protect the world, it was founded to to protect the people who have entrusted it with the power to do so. Based on the fact we are prosperous, don't have wars inside our borders and enjoy a life where we are free to pursue our own interests, our government is a success.

    As for hypocrisy, why does that even matter? Last I looked, hypocrisy wasn't a crime. Regardless, the US is not hypocritical. We are simply pursuing policy that is in our interest. What you seem to fail to grasp is that policies in the interest of other nations are often contrary to what is best for your own nation.

    Do we need ANOTHER WMD? The answer is, we don't.
    That's fine if you want to be bullied around by other nations. But I think I can speek for anyone who values freedom here: I'd rather have the next WMD in our arsenal than anyone else have it. Better my country be able to threaten a foreign power than be threatened by one.

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    -- $G
  11. Re:US is the only world power by Dolly_Llama · · Score: 4, Insightful
    First, there is no such thing as an illegal war. Frankly, there's hardly such a thing as a civilized war. Who has the athority to say "war is legal" and "war is illegal"?

    Well if you consider the UN charter a treaty that the US has agreed to, then you look at that charter, especially where it says "The Organization is based on the principle of the sovereign equality of all its Members" and "All Members shall refrain in their international relations from the threat or use of force against the territorial integrity or political independence of any state, or in any other manner inconsistent with the Purposes of the United Nations."

    Then you can easily draw a conclusion that the new policy of premption is in contradiction with existing US treaty obligations.

    We are simply pursuing policy that is in our interest. What you seem to fail to grasp is that policies in the interest of other nations are often contrary to what is best for your own nation.

    This can be true, but international relations is not a zero-sum game. What goes around comes around.

    And it will come around...

    --

    Somewhere, something incredible is waiting to be known. -- Carl Sagan

  12. Very few people understand statistics by jaaron · · Score: 4, Insightful

    That was a very well written post and I agree with you that most Americans do not understand the facts. But then, neither do the French, the Russians, the Chinese, heck, the entire human race's ability for objectivism and rationality could be seriously questioned. Which is the point of my response.

    While I as an American certainly do not want to let my government and my society (including myself) off the hook, laying the guilt of 3,000,000 or 6,000,000 deaths soley on the heads of America is an abuse of the facts. Violence is a global failure, not a localized one. Aggressors should be identified and appropriately dealt with (US included) -- but to excuse all other parties is to participate in a witch hunt.

    I leave you with one question: Suppose the US had not killed all those people. Suppose the US had never gotten involved anywhere. Can you confidently conclude that the gross level of violence and death in the world would be any less?

    There is more than one player in the world. And we ALL share in these iniquities. The violence of the US, Rwanda, Palestinians and Jews is violence of humanity and we each share in the failure.

    --
    Who said Freedom was Fair?
  13. Re:US is the only world power by cje · · Score: 3, Insightful

    The public was not ignorant about the war in Iraq.

    I suppose this is why over two thirds of Americans believe that most of the 9/11 hijackers were Iraqis. I suppose this is why most Americans believed the administration's rhetoric about massive stockpiles of "ultimate weapons" in Iraq. I suppose this is why 48% of Americans believed that there were close ties between Saddam Hussein and Osama bin Laden, and why 25% believe that we have found WMD in Iraq and that world opinion was strongly behind the Bush administration in the days leading up to the war.

    Perhaps "ignorant" is not the right word. "Gullible" might be more like it. After all, most of the folks who held (and continue to hold) any of the above misconceptions were just believing what they were being told by the administration and the media. As the days go by and more and more of this material is revealed to be misleading, incomplete, or outright untrue, it will be interesting to see what the reaction is.

    We are simply pursuing policy that is in our interest.

    Oh, how I wish that were true.

    --
    We're going down, in a spiral to the ground