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Weighing An Attogram

Roland Piquepaille writes "Researchers at Cornell University have reached a new level of precision by measuring objects with a mass of less than an attogram (10^-18 gram). They used a silicon cantilever oscillator to measure small dots of gold. But their real goal is to detect and identify viruses. The team also wants to reduce the size of the cantilever, extending the sensitivity well into the zeptogram (10^-21 gram) range. This summary contains more details and an image of a small gold dot resting on the silicon cantilever they used to achieve this breakthrough."

19 of 42 comments (clear)

  1. New tests for gravity. by G4from128k · · Score: 4, Interesting

    If they can use this to measure very small forces on very small objects, they might be able to construct some interesting tests of gravitational fields or of quintessence. We all think gravity changes with 1/r^2 and is irrespective of material composition, but do we really know that this rule works for ALL ranges of mass, distance, and material?

    Inquiring physicists want to know and this innovation could help them know it.

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    1. Re:New tests for gravity. by marcus · · Score: 5, Informative

      Your question reveals some confusion, perhaps produced by the wording of the article.

      They are not "weighing" anything. They are measuring the mass of the gold. These are two different things. Gravity is not involved in the latter.

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    2. Re:New tests for gravity. by QuantumFTL · · Score: 4, Informative

      If they can use this to measure very small forces on very small objects, they might be able to construct some interesting tests of gravitational fields or of quintessence.

      I don't really think that this technology in its current form can measure the forces on a particle that size. If you read the article, it is measuring the mass by measuring the resonant frequency, not measuring the forces present on the object.

      Yes I know that external forces can shift the frequency (due to nonlinearity) however I do not think that the precision of the device allows for measurement of such a weak effect.

      This has little to do, as another poster metioned, with other forces masking things at this small scale, but rather with the fundamental nature of the measuring device.

      Disclaimer: I'm a semester away from my BS in physics.

      Cheers,
      Justin

  2. How many... by dnahelix · · Score: 3, Interesting

    How many atoms of gold is that?
    Very fascinating! I love the picture.

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    1. Re:How many... by Patrik_AKA_RedX · · Score: 5, Informative

      Au: 197g/mol
      10E-18 / 197 = 5.076x10E-21 mol
      5.076x10E-21 x 6.022x10E23 = 3056.8 gold atoms.

    2. Re:How many... by Anonymous Coward · · Score: 2, Funny

      I was going to make a joke about atoms being atomic... ahh forget it.

    3. Re:How many... by Patrik_AKA_RedX · · Score: 3, Funny

      It means one atom is for only 80% part of the attogram. The other 20% is part of the attogram next to it.

      Or: 3056 gold atoms and a Gd atom (157.3ame ~80% of 197.0ame).

      Or: I broke one of the gold atoms, there quite fragile, you know.

    4. Re:How many... by Beryllium+Sphere(tm) · · Score: 3, Interesting

      Nostalgia department: there was one Asimov novel where a character is walking through a lab, and to convey a sense of wonder Asimov says the lab has a scale capable of weighing a billion atoms.

      I think it was one of the Caves of Steel series.

      Not only can we weigh things, we can identify them at infinitesimal quantities. There was a fact article in Analog about analytical chemistry. There are sensors today that can match the sensitivity of a dog's nose. That field has been advancing at the same explosive rate as computer performance has.

    5. Re:How many... by Anonymous Coward · · Score: 2, Insightful

      that's cool. I'm guessing it should be rounded to an integer.

      Actually... with his calculations it should be rounded to 3060 because there are only three significant figures in 197g/mol

      Obviously it gets the point across either way though.

  3. Tests will be difficult by Spamalamadingdong · · Score: 5, Insightful

    At that scale, influences like Van der Waals forces become far more powerful than gravity. Reading the pull of gravity with all the EM-related forces at work seems like a very, very difficult job.

  4. Ah, finally... by blate · · Score: 2, Funny

    ...finally a way to weigh my post-dot-com crash paycheck. :D

  5. Weight Via Chaos Theory by Doug+Dante · · Score: 3, Interesting

    I had this idea, which I've never implemented, of weighing items with extreme precision using a chaotic system. Since the chaotic system is sensitively dependent upon initial conditions, it should be possible to take measurements over a short period of time and work backwards mathematically to one of several possible initial weights. Eliminate those values that are not possible via other means (negative weights, far too heavy, far too light), and you should end up with an extremely accurate initial weight.

    I'm not sure that it would really work in practice, but I just thought it was a neat idea, and vaguely related to the authors' use of an oscilator.

    Perhaps if they were able to make the position of the oscilator at any time sensitively dependent on initial conditions, they could invent such a measurment tool (e.g. swing another weight in and out based on the position of the oscilator to slightly modify the local gravity in a nonmodal fashion that would make the oscilator sensitively dependent upon its weight and its inital position)

    My differential equations work is so far gone, I couldn't even begin to measure this mathematically anymore.

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    1. Re:Weight Via Chaos Theory by Baron_Yam · · Score: 4, Interesting

      Actually, this has already been done... though with optics. You take large numbers of measurements of 'nothing' and note the random static produced by the sensor. You can then subtract the average noise from the average of a large number of measurements of something and get an accuracy level theoretically beyond the ability of your instrument.

    2. Re:Weight Via Chaos Theory by PD · · Score: 3, Informative

      The problem with this is that your system is chaotic. If you measure it one way, you can't tell how it's going to turn out. If you measure it the other way, you also can't tell how it began.

      And, the number of possibilities you have for a starting state would probably depend on just how sensitive your system is. If there's not many possibilities to choose from, then your system is probably insensitive enough to get an accurate measurement right up front.

      But it's a cool idea that would probably make a good gimmick in a sci-fi story.

  6. It will just grow back then... by Jru+Hym · · Score: 2, Funny
    But their real goal is to detect and identify viruses.

    A virus is what we doctors call very very small. So small in fact it could not possible have made off with an entire leg.

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  7. Re:Zeptogram? by cicadia · · Score: 5, Funny

    About 1.4x10^-11 microns/zL on the highway, 8x10^-12 or so in the city. Although I think that mileage is more commonly measured in zeptolitres per 100 Angstroms these days.

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  8. Zeptogram? by whistler36 · · Score: 3, Funny

    The zeptogram was never as popular as the grouchogram. People only use it because it's better looking.

  9. Identifying a virus by weight.. by Copious1 · · Score: 2, Funny

    Damn little bastards will become weight concious and go on a diet just to elude detection.

  10. I can't be the only one thinking this.... by System.out.println() · · Score: 2, Funny

    But their real goal is to detect and identify viruses.

    Maybe they should license this technology to Microsoft?