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Paralyzed Woman Walks Again

mgv writes "It's been promised for years, but it's just become a reality. Stem cells taken from cord blood have enabled a paralysed woman in South Korea to walk again for the first time in 20 years. The details are on the Sydney Morning Herald Site which requires registration, but can also be seen on the World Peace Herald. Too late for Christopher Reeve, but not for the thousands of new injuries worldwide each year or the millions of paralysed people from other diseases in the world."

40 of 1,196 comments (clear)

  1. Adult stem cells by Anonymous Coward · · Score: 5, Informative

    Cord blood stem cells are considered to be adult stem cells, not embryonic stem cells. Just wanted to get that out before all the Bush bashing starts.

    1. Re:Adult stem cells by bombadillo · · Score: 4, Informative

      Stem Cells are not the same as embryo's. A stem cell is called a cell for a reason. The human body sloughs off millions of cells a day. Also, stem cells are often left over from invitro fertilization. Are you against invitro fertillization? Whats wrong with using any left over cells which cannot continue to exist and using them for research?

    2. Re:Adult stem cells by RazzleFrog · · Score: 2, Informative

      Oh yes. That's right because not believing in God automatically makes me an unethical human being. Religion is often used to defend an unethical behavior. How often do you hear of atheists killing or bombing because of their beliefs (or lack thereof)?

    3. Re:Adult stem cells by Daniel+Dvorkin · · Score: 2, Informative

      too often scientists will ask themselves "can I do this", instead of "should I do this?"

      In Hollywood, that's true. In the real world, most scientists are very concerned about the ethical implications of their work -- more so, in fact, than people in just about any other field.

      --
      The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
    4. Re:Adult stem cells by DunbarTheInept · · Score: 2, Informative

      It's hard to separate because it's been going on for so long now. Religions mirror the culture in which they were formed and altered over the years. So too do ethics. Thus the ethics of a people, and the religion of a people, tend to match up one to one. I tend to blame the culture, not the religion, but I also *credit* the culture, not the religion. That means religion doesn't get the blame for the inquisition, but religion doesn't get the credit for abolitionist movements in the US, even though it was part of the rhetoric of both. People tend to decide right and wrong first, and then try to force their religion to fit that. That's how you can have both Christian abolitionists and Christian slavers, and how you can have both Muslim's saying their religion is all about peace, and Muslims who fly passenger airplanes into buildings.

      People decide ethics first, and then force their religion to fit what they've already decided. I'd feel more comfortable without that extra unneccesary step, so at least a person's rationale is laid bare for all to see, without masking it by religion. So, I too would trust an atheist more than a religious person, but not because atheists are inherently more ethical - but because they are inherently more open about our motivations. If an atheist is evil, I'm more likely to be able to detect it openly.

      --

      Don't label something "offtopic" unless you know the topic well enough to tell what's on topic.

    5. Re:Adult stem cells by mbrod · · Score: 1, Informative

      The U.S. Federal government is not providing tax relief to religious organizations, it has made them exempt from having to pay taxes.

      For relief you would need a tax in the first place to relieve them of, which there has never been.

    6. Re:Adult stem cells by You+Been+Rob-ed! · · Score: 2, Informative

      Hey there Anonymous Coward, I think you have it reversed. When you hear "stem cell research" on the 6 o'clock news, they're invariably talking about embryonic stem cell research as though it's the only kind. You never ever hear of successes in adult stem cell research on network news. All you ever hear is how the crazy religous right is holding back "stem cell research".

      --
      For fun, calculate how much DDT would be lethal for you!
    7. Re:Adult stem cells by foooo · · Score: 4, Informative

      It is often impossible to separate "moral" issues from "legal" issues. For example... why is murder illegal?? Because it's immoral to murder someone.

      This is why abortion and embryonic stem cell research are such touchy issues. The issue at hand is not "is murder wrong" it is instead "is this considered a person? and therefore ceasing it's existance is considered murder??"

      Statements such as:

      "Justification with something so simple as "my morals happen to be correct" isn't acceptable. The government either needs to stop making moral issues legal issues. Doing so would have the potential to save thousands of lives."

      are childish, in that they completely ignore that law is entirely based on moral issues. We define what constitutes life, liberty and property entirely based on morals. Law simply codifies our societal morals.

    8. Re:Adult stem cells by Noofus · · Score: 2, Informative

      The thing about embryonic stem cells is that they havent become differentiated yet. Its easier to tell an embryonic stem cell to become a liver cell or a stomach cell or a brain cell or a spinal cord neuron or whatever. Adult stem cells are easy to obtain but they dont as readily become whatever you want them to become.

      The umbilical cord blood appears to contain stem cells that are somewhat half way between embryonic and adult. They arent as easy to coax into doing your wishes as pure embryonic cells are but they are also not as stubborn as adult cells.

  2. Lets get this out of the way by stecoop · · Score: 3, Informative

    Ok George Bush didn't outlaw Steam Cell Research; He ceased giving federal funding for new steam cell lines. And remember he was the first president to start giving money to this kind of research. At least read his statment first and then search google to get the facts

    Even after that before you start bashing, ask who should be in charge of developing medicine - the government or industry?

    1. Re:Lets get this out of the way by Pxtl · · Score: 2, Informative

      Ahh, meanwhile you use the "talking points" style terminology and proudly display your brainwashing. Embryonic - not fetal. Different things. Calling it a fetal stem cell makes it sound dirtier, and shows that your source material is stupid fundies.

    2. Re:Lets get this out of the way by Oxy+the+moron · · Score: 2, Informative

      Perhaps I'm just not seeing the logic... but how is adding a $1,000 per ounce tax to tobacco equivalent to cutting federal funding for stem cell research? We aren't taxing scientists for stem cell research...

      I agree with the parent. He didn't outlaw it, practically or otherwise. There are many research opportunities not funded by the federal government that are successful. Cutting funding may slow down research, but it isn't outlawing it or killing it off.

      --

      Proudly supporting the Libertarian Party.

    3. Re:Lets get this out of the way by Roxton · · Score: 2, Informative

      As a libertarian, you might argue that if the Federal government weren't funding research, the private sector would do a terrific job. I don't agree, but for the sake of the discussion, let's say I conceed the point.

      But as it stands, the existing infrastructure for getting funding is *not* privatized. The presence of such a public infrastructure inhibits the development of any such privatized infrastruture. Within the current, federally funded system, getting solid funding for fundamental stem cell research is a virtual impossibility. If you tried to convince any scientist otherwise, he'd fall on his ass laughing.

  3. Other Links by lamz · · Score: 4, Informative

    No subscription required for the story here, either.

    --

    Mike van Lammeren
    It will challenge your head, your brain, and your mind.

  4. Re:Not for the US by brandonp · · Score: 4, Informative

    You're wrong.

    This was done by using umbilical cord stem cells. This has far fewer ethical problems and George Bush said on many occassions he fully supports the use of umbilical cord stem cells.

    This is a huge advance, getting results without the ethical issues that many people struggle with.

    Brandon Petersen
    Get Firefox!

  5. Re:paralySed? by General+Wesc · · Score: 2, Informative
  6. Re:Take that, Bushies! by corbettw · · Score: 4, Informative

    and show the Bushies that they are dumb (at least as far as science goes).

    At least we know how to RTFA. The stem cells used were umbilical stem cells. You know, the type Bush wants to encourage people to use? As opposed to fetal stem cells, which are just covered in ethical and moral dilemmas.

    --
    God invented whiskey so the Irish would not rule the world.
  7. Re:Not for the US by dmusicstud · · Score: 3, Informative

    Agreed.

    From the Korea Times: http://times.hankooki.com/lpage/200411/kt200411261 7575710440.htm

    Kang added that since cord blood stem cells are later than embryonic stem cells, they have little chance of causing the fatal teratoma. ``Embryonic stem cells are omni-potent in that they can divide into any thing even including a tumor cell. But cord blood stem cells are developed enough not to cause such troubles while retaining as powerful a differentiation capacity at the same time,'' he claimed.

    Let's forget about the moral/ethical reasons for not pursuing embryonic stem cell research - let's look at it from a scientific (*gasp* - a conservative Christian talking about science!) point of view. Less capacity to cause cancer = a good thing, no?

    - Another Brandon (my last name is Danner)

    --
    One ring to rule them all, and in the darkness named them...
  8. This ball was never in Bush's court to begin with by mark-t · · Score: 4, Informative
    The Bush administration only outlawed funding for _fetal_ stem cell research. This was from the umbilical cord and is sanctioned by the US's current government.

    Why is it that when some people hear the term "stem cells" the same sort of knee jerk reaction happens just like when some people hear the term "nuclear power"?

  9. Re:Umbillical Cord Use Actually WORSE by Zapdos · · Score: 2, Informative

    Cords are provided at birth

  10. Re:Cord blood vs. embryonic? by MagicM · · Score: 5, Informative

    From here:

    So-called "multipotent" stem cells -- those found in cord blood -- are capable of forming a limited number of specialised cell types, unlike the more versatile "undifferentiated" cells that are derived from embroyos.

  11. Get the facts straight by nwbvt · · Score: 5, Informative
    Embryonic stem cell research was not banned. Federal funding was given for embryonic stem cell research but limited to pre-existing lines.

    There is a huge difference between the two.

    --
    Mathematics is made of 50 percent formulas, 50 percent proofs, and 50 percent imagination.
    1. Re:Get the facts straight by magefile · · Score: 5, Informative

      Pre-existing lines that are contaminated with pathogens and mouse cells, many of which have reached the end of their useful lifespans. It's effectively a ban on federal funding, period.

    2. Re:Get the facts straight by nwbvt · · Score: 1, Informative

      Regardless, it is more than no funding at all (like how it was before Bush) and in no way effects private funding. Claiming that it is a ban or leaving out the "federal funding" part is either wrong or disingenuous.

      --
      Mathematics is made of 50 percent formulas, 50 percent proofs, and 50 percent imagination.
    3. Re:Get the facts straight by Tiroth · · Score: 4, Informative
      Regardless, it is more than no funding at all (like how it was before Bush)
      This comes up a lot, and I think it is a very disingenuous argument. There was no funding before Bush because stem cell research as we contemplate it today is essentially an entirely new field of research; there wasn't significant work being done on human embryoes before Bush, hence no funding.

      Reference below. It was not until 1999/2000 that scientists proved that these cells could be forced to differentiate into things like nerve cells that were previously thought to be impossible to regenerate.
      http://www.laskerfoundation.org/news/ stemcell/hist ory.html
  12. Re:Dictionary.com by 32bitwonder · · Score: 2, Informative

    Try looking in a non U.S. centric dictionary.

  13. Korean times article with a picture by Wm_K · · Score: 2, Informative
  14. Re:i only hope... by bluefoxlucid · · Score: 3, Informative

    This is a reproducable advance. Many diseases have been cured in this method. In one experiment now, bone marrow stem cells are being grafted onto hearts. The patient's heart is stopped for 2 minutes to allow the cells to graft. After that, it's restarted. Any scar tissue from heart attacks is healed and becomes healthy, strong heart muscle tissue.

    Talk of curing diabetese with this has also floated around; and over a hundred diseases have already been treated successfully.

  15. Original Korea Times Article (in English) by dokebi · · Score: 3, Informative

    with some additional details here

    --
    In Soviet Russia, articles before post read *you*!
  16. Peer review? by schodackwm · · Score: 2, Informative
    not at these papers/wireservices, I think.

    May be worth all these words if/when the claim is supported by detail in a peer-reviewed journal, as opposed to a News Corp (read: "tabloid publication, regardless of the actual paper size) and/or Agence France Press, which, like AP, UPI, and others, frequently distributes stories printed by others without factchecking.

    --
    [this sig has been trunca
  17. No surprise this is in North Korea. by Helpadingoatemybaby · · Score: 2, Informative
    Too many people think that "Bush is the first president to fund stem cell research" and "these were umbilical stem cells, and, uh, have nothing to do with embryonic stem cells!"

    The fact is, California alone gave $3 billion for research into this. Bush claims to have donated $25 million -- translated, California gave 120 times the amount that the Bush talkingpointists trumpet.

    Then Bush said that there were something like 75 stem cell lines, and it turned out that something like 60 were garbage and entirely unusuable, and the last 15 might be useful, or might be contaminated.

    As for "Bush was the first one... etc." -- considering that stem cells started to show real promise in 1999 and 2000, it's not too surprising that the previous research funding wasn't broken out separately. It IS offensive to me that the were so many restrictions on research to put us behind the South Koreans and to bury Christopher Reeves.

    And to those who claim that "well these were not embryonic stem cells!" No one here can get to stage 2 before starting at stage one, which is embryonic.

    Clearly we must give these IVF embryos the respect they deserve -- by throwing them in the garbage rather than saving lives.

    You can see that that the "Bush was first" stuff is false here:

    In August 2000, HHS, under President Clinton's leadership, published new guidelines for research using human embryos. These guidelines create a loophole that essentially claims if privately funded scientists destroy the embryos and extract their stem cells, government-funded scientists can conduct experiments with those stem cells without violating the federal ban. 9

    On August 9, 2001, President Bush announced he would reject the Clinton Administration's guidelines and only allow federal dollars for research on approximately 60 existing embryonic stem cell lines already created in privately funded laboratories.10 The president outlined four conditions for the use of existing cell lines:

    * The embryos were destroyed and the cell lines were created before the August 9 speech

    * The embryos were among the "excess" frozen embryos stored in fertility clinics created through in vitro fertilization for reproductive purposes

    * The parents gave their consent for the embryo to be destroyed

    * The parents were not offered any financial incentive in return for donating the embryo 11

    --

    The baby's fine -- please stop sending business cards.

  18. Re:Adult Stem Cells :) by tgibbs · · Score: 4, Informative

    There's something wrong with a bunch of blood thirsty, power hungry mongrals who are willing to draw attention to something that has so far been proven in 100% of laboratory tests to be totally useless

    Do you really feel that your argument is so weak that it is necessary to lie? If you go to PubMed and type in "embryonic stem cells," you will see a long list of laboratory studies supporting their value.

  19. Re:Nonsense!!!! by stanmann · · Score: 5, Informative
    Q: In 1 Ki 7:23 and 2 Chr 4:2-5, does the Bible say the value of pi is 3? A: No. The skeptical Asimov's Guide to the Bible p.328 claims, "The explanation is, of course, that the Biblical writers were not mathematicians or even interested in mathematics and were merely giving approximate figures. Still, to those who are obsessed with the notion that every word in the Bible is infallible (and who know a little mathematics) it is bound to come as a shock to be told that the Bible says that the value of pi is 3." Asimov had a Ph.D. in chemistry, so he should have known better. There are three different possibilities. Rounding with significant digits: Assume the circumference was exactly 30.0 cubits. Since they only gave the dimensions in whole numbers, which number would Asimov have them use? A perfectly round basin with no rim would give a value of 9.55, and that is closer to 10 than to any other number. A rim: Assume either the inner circumference was exactly 30.0 cubits, or that the thickness of the basin made the inner and outer circumference almost the same. A diameter that included a rim of 4 inces (0.22535 cubits) would give a ratio of exactly 3 to 1. A flare: Nothing says the walls of the basin were perfectly vertical. If the basin had a very slight flare of 0.75% at the top, then the outer circumference at the narrow part and the outer or inner diameter at the top would give a ratio of exactly 3 to 1.


    11/10/03 "Sir-In the News story about scientists' response to creationists, the scientists `comment that the Bible says that PI is 3, not 3.14' (Nature 398, 453; 1999). The biblical verse quoted (1 Kings 7:23) reads in part: `...measuring 10 cubits from rim to rim... It took a line of 30 cubits to measure around it". Indeed, 30/10 equals 3, but further on in verse 26 it says: `It was a handbreadth in thickness...' Assuming that a cubit measured 18 inches and a hand breadth 3 inches, the inner diameter of the bowl would be 174 inches (10 x 18 - 2 x 3), and the inner circumference would be 540 inches (30 x 18). This yields a value for PI of 540/174 or 3.10. This is about a 1 per cent error from the typical value for PI of 3.14. Although we do not know the exact length of a cubit or a handbreadth, this result is very close to the actual value of PI." (Peil K., "Biblical answer to cooking up pi," Nature, Vol 399, 10 June 1999, p.522)
    --
    Food not Bombs is a nice platitude but it breaks down when you notice that the Bombees are usually well fed
  20. Re:Yes, the gov't should fund it, and here's why.. by gokeln · · Score: 2, Informative

    Actually, the calculus was invented more than a millenia earlier by Archimedes. Google for plimpsest. Who employed Archimedes? Oh, and what about Leibniz?

    --

    There's no time to stop for gas, we're already late.
  21. What is holy by anomaly · · Score: 4, Informative

    I can't speak for all of the Christian world, but I have to take issue with a couple of your points above:

    1. If God made things a certain way, then that must be holy.
    In fact, the Hebrew scriptures (read Old Testament) and the New testament affirm that the world in which we live is flawed as a result of the sin of Adam. Humans - as they are naturally - are not holy. In fact, humans are not naturally able to relate to God. It is only through the combination of God's reaching out to man and man's response to that call that give people any hope of relating to God. (There are many internal discussions about the nature of that call, and man's ability to respond, but the core belief is that man as he is born, is unholy.)

    People are born with a prediliction to reject God in a myriad of ways. Some alcoholism has been shown to have physiological roots, but that does not prevent the church from condemnation of abuse of alcohol. Even if homosexuality is demonstrated to have a physiological cause, it will not mean that the church needs to change its stance.

    Homosexual behavior is condemed by the church, as is idolatry, lying, theft, greed, slander, swindling, gluttony, and much else.

    Why are these behaviors condemned? Because God made us, and He knows how we work. You can drive nails with a Rolex, but it wasn't made for that. There are many things you can do with and to your body - but it wasn't made for those things.

    The maker - designer - knows what is good for you, and what is not. He can set whatever standards He wants. God gives us the free will to follow His direction or reject it. I'm sure that the Rolex folks won't recommend driving nails with your watch. If you do it anyway, there are consequences. It's the same with God.

    As it stands, the revealed word of God says that sexual acts outside of marriage, and also with two people of the same gender are not acceptable. In fact, Jesus Himself said that when a man looks at a woman lustfully he has already sinned - and that sin carries the same penalty as homosexual acts do!

    2. with embryonic stem cells there is no sper involved
    I believe that you misunderstand the definition of embryonic stem cells. An embryo is the joining of sperm and egg. Evangelicals typically believe that life begins at conception, not at a later point. When life begins, it must be protected.

    Respectfully,
    Anomaly

    --
    But Herr Heisenberg, how does the electron know when I'm looking?
  22. Not Inevitable by SeanDuggan · · Score: 2, Informative
    Once conception has taken place, it is inevitable that birth will take place.
    First, on a technical level, after conception, the egg has to go through implantation. Due to semantic juggling, that's why "contraceptives" like the Pill don't do anything to conception. Rather, they prevent implantation.

    Secondly, there's a variety of things that can happen after conception that prevent birth from spontaneous abortions (the body absorbs everything back) to miscarriages and other in-womb deaths. Although, arguably, the baby is still "born" in the latter two cases, just not alive.

    --
    This sig has absolutely no significance and serves only to take up screen space and waste the time of the reader.
  23. Re:Just a side note.... by Kehvarl · · Score: 1, Informative

    By the way, Sagan, while brilliant, has been wrong before. Look at his black hole theor which her changed to the opposite of the original last year.

    You really mean Sagan, and not Hawking?
    Note: This is completely aside from whatever your post was about (I didn't really read it) so this probably has no bearing whatsoever on the overall correctness of your post.

  24. Re:Time for political will to change??? by lukesl · · Score: 3, Informative

    Impeding and not funding are different things. An imposition is banning or blocking or imposing harsh regulations.

    If they just declined to fund research proposals involving ES cells, you would be right. However, the ban on federal funding of ES cell research is more restrictive than that. Most labs have several sources of funding and multiple projects going on simultaneously, and almost all basic science biology labs get funding from the government. If I were in a lab doing ES cell research, even work that was privately funded, I would essentially have to work in a separate facility from everyone else. I couldn't use the lab centrifuge, geiger counter, refrigerator, incubator, etc., because those were bought with federal dollars. On a practical level, it's extremely difficult, if not possible, to work under those conditions. So in practical terms, it is a ban.

    The bottom line is that the issue here is the future development of "factories" of human bits and pieces. It frightens people. Embryonic stem cells are thrown away, but we both know that in short order they would be harvested efficently and clinically with absolutely no regard to their nature: much like antibodies or animal specimens are harvested today.

    That's a silly, alarmist view. Or maybe it's true. Maybe ES cells will lead to both matrix-style baby factories AND the cures to terrible diseases. Couldn't we just ban baby factories?

    It is hardly disturbing that the government would elect not to fund a practice which is very fairly consider contraversial for a pay-off that is available through other means or highly hypotethical. Bush has said repeatedly that if other avenues are exhausted or the circumstances warrant it a revisitation of the issue can be made.

    What you're saying here is partially misguided and partially factually incorrect. I would argue that the only reason it is controversial at all is because politicians decided to make an issue out of it. We've been throwing the cells in the trash for years, and nobody cared! Bush wants to appear somewhat flexible on the ES cell issue because he KNOWS that the ban will be lifted in the future, because it will very quickly become politically unpopular once the Swiss (or whoever) cure diabetes (or whatever). This, really, is what bothers me most. Bush is not an idiot, and he understands the promise of ES cell research. He even knows that his opposition to funding the work is bad for the US (but maybe only a little), but he's willing to do it because he knows it will win him votes among people who don't understand the issue. Unfortunately, only about 2% of the general public understands the issue.

    As far as the promise being "available through other means or highly hypothetical," the evidence right now is against that. We can cure some diseases in mice using ES cells, and there are things we can only do with ES cells, etc. I would say that if you can cure a disease in a mouse, it's not "highly hypothetical" to think that you could use the same strategy to treat a human.

  25. Have you read it yourself? by anomaly · · Score: 4, Informative

    The old testament, and new testament affirm nothing.

    Have you read the Bible yourself? All of it?

    While you may believe that it is merely a collection of nice stories that are used to prove a point, I would suggest to you that your belief may not be completely accurate.

    The Bible is quite remarkable in terms of ancient literature. There are many many 'holy books' that are revered by religious peoples around the world. None of them have had the impact on Western culture and society that the Bible has.

    We know that what is written there has been preserved since its original versions because of the vast number of copies that we have. There are more accurate copies of the Bible than ANY other ancient work. (The alleged discrepancies that many of you want to point out as you read this are completely irrelevant to all major doctrines of the Christian faith.)

    To suggest that it's merely a collection of stories on a par with mother goose is a bit...unreasonable.

    In terms of disease, the Christian faith teaches that we all are diseased, and are in need of an ultimate physician to heal us. The disease is sin, evidenced by our selfishness and pride. This is what separates us from a Holy God.

    God does give us free will. Doing what He says is wrong is, as I mentioned in my last post to you, akin to smashing your gold Rolex on a galvanized nail.

    If you do what God says is wrong, you can expect that there will be consequences. That's the way it is. You don't have to like it, but you can't change it, either. The only way to avoid the consequences is to believe that you are imperfect, recognize that perfection is required to have relationship with a holy God, and ask Him to accept you in your imperfection, beacuse of Christ's sacrifice on your behalf.

    This is completely unrelated to procreation. Procreation is not at issue if you look lustfully at a woman, and Christ called that sin, too.

    WRT your embryonic stem cell point, I believe that you are mistaken. This site states that embryonic stem cells require a fertilized egg.

    --
    But Herr Heisenberg, how does the electron know when I'm looking?
  26. Re:Atrophy? by mgv · · Score: 2, Informative

    I get the feeling there must be more to the story than meets the eye here. If this woman had been paralyzed for 20 years, wouldn't her muscles be atrophied? Even if you repaired the nerve damage, it seems to me she wouldn't have just been able to get up and walk, at least without a lot of restorative therapy.

    Is there something I'm missing here?


    Yes, if you read the article she is walking with a frame. Still, she is improving alot faster than the medical staff expected.

    Michael

    --
    There is no cryptographic solution to the problem where the intended receiver and the attacker are the same entity.