Needle Free Injections With Microjets
IZ Reloaded writes "Do you hate needles? In the near future, the fear of needles would be a thing of a past. Bioengineering students at the University of California, Berkeley have developed the MicroJet. It uses an electronic actuator that could one day propel vaccinations, insulin or other drugs through the skin of the patient - without the device even touching the skin - with far less pain than a hypodermic needle."
And they've had "needle-less" injectors around for a long while, however the current ones are expensive and rather inaccurate at dosing when compared to needles.
However, I must say I really don't care if they come out with a needle-less injector that works better. It's not the shots themselves that bother me, but rather the constant maintenance that people take for granted. I'd still need to do something. Right now I have a pump, and it's better than doing individual injections, but it's always with me. I'm waiting for the day when I no longer have to worry about this disease any longer because I've been cured.
Someone got his blog pointed at slashdot, while I love the subject, its 4 days old, been on blogs for 3 days and a poor cut and paste job from the original Press release.http://www.berkeley.edu/news/media/release s/2005/03/16_microjet.shtml :)
Read the press release, its better
I got vaccinated with an "air gun" back in the day. it hurts, probably as much as a needle. But you can do a whole group of people quickly, 'cause you don't need to change needles.
Sounds similar to the jetgun the military use to use. Does anyone know the difference?
Well, they're promising "far less pain" with this device.
Once upon a time, I had the misfortune to receive a yellow fever vaccination with one of the military's needleless injectors. It felt like some steroid-pumped baseball player had swung a bat at my shoulder. Nearly as bad as the pain was the gathering anticipation of the pain, as I watched the 200-odd people in line ahead of me get their shots.
I was diagnosed with Multiple Sclerosis four years ago (at the age of 22). Then, the best treatment available was Avonex, which is given intramuscularly once a week. The needle is about 26 gauge and 1 1/4" long. With that needle, the pain was mostly psychological. There is nothing natural about stabbing yourself with a long, sharp object.
:-)
In fact, up until about a century ago, sharp objects piercing into your body has generally been a detrimental event. It meant that you were being bitten (with poison or germs getting injected past your outer layer defenses) or you were getting punctured by something that would result in an infection. So everything about your physical makeup and your psychology is evolved to consider injections to be a bad thing. In a twist of events, now it turns out that shard objects getting jabbed into your body is mostly a beneficial thing. But it will take a long time for evolution to change our aversion to injections. And with new technologies, it may not even be necessary for that adaptation to occur. I certainly hope this becomes the case in the *very* near future.
The nerves on the surface of your skin tend to cluster. So, the amount of pain related to the actual puncture of the skin varies greatly, depending on whether or not you happen to hit one of those nerve clusters. Sometimes the penetration of the skin would result in a strong pinching sensation; other times, I would not feel anything at all. For the intramuscular injections, it is also possible that you will hit another nerve on your way into the muscle tissue. That usually just results in a reflex reaction (you jump or twitch). The act of the actual injection is painless, since the solution is injected far below the surface pain receptors. But then you tend to get long-term dull pain similar to a charly horse; it's like a blunt end of a stick whacked you in the thigh and you have a nice bruise in your muscle. And $deity help you if you happen to hit your bone with the tip of the needle.
About a year ago, I switched therapies to Rebif, which is given subcutaneously three times a week. The needle is a smaller gauge and is signifianctly shorter (~1.5cm). It is unintuitive, but the subcutaneous injections, even though the needle is shorter and thinner, are much more painful than the IM injections, because the solution is injected just below the surface of the skin, where you have a lot more pain receptors. So it's not the needle really that I worry about. I hardly even feel that any more; it's the stinging sensation from the liquid getting pushed into the subcutaneous tissue just below the skin.
I use a spring-loaded injection contraption that hides the needle from my view entirely; I just hold the casing to my skin and push a button. The spring-loaded plunger pushes the needle in and presses the plunger of the syringe down to inject the medicine. I don't even worry about the needle any more; I worry about the sting with the liquid getting pushed under my skin and the subsequent itchy and burning red blotch that stays in that area for weeks afterward. So in my case, at least, the needle is a non-issue; this needle-less technology is neat, but it will not help with the pain associated with liquid getting pushed under my skin, and it will not help with the site reaction.
Wake me up when they figure out how to effectively administrate interferon-beta with a pill.