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Needle Free Injections With Microjets

IZ Reloaded writes "Do you hate needles? In the near future, the fear of needles would be a thing of a past. Bioengineering students at the University of California, Berkeley have developed the MicroJet. It uses an electronic actuator that could one day propel vaccinations, insulin or other drugs through the skin of the patient - without the device even touching the skin - with far less pain than a hypodermic needle."

17 of 282 comments (clear)

  1. Insulin jet injectors are NOT NEW by way2trivial · · Score: 4, Informative

    here's one for sale
    http://diabetic-supplies.medical-supplies-equipmen t-company.com/product/PPF/ID/4200/new_prod_full.as p

    Medi-Jector Vision(tm)Needle-Free Insulin Injection System
    Accurate delivery of insulin injections from 2-50 units in 1 unit increments. Injector reusable for 3000 injections. No maintenance or cleaning required. Smaller, lighter weight and easier to use than previous models. Contains: injector, carrying case, training video, instruction manual, 2 Needle-Free Syringes (for easy and medium skin penetration) and 1 vial adaptor. Replacement Needle-Free Syringe kits sold separately.

    what's amazing here?

    --
    every day http://en.wikipedia.org/wiki/Special:Random
    1. Re:Insulin jet injectors are NOT NEW by mike5904 · · Score: 5, Informative
      From TFA:
      "The researchers modified a traditional syringe by taking out the needle and adding a tiny piezoelectric actuator that propels the liquid out of the tube. The actuator expands or contracts in response to an applied voltage. Because the MicroJet's source of power is electrical rather than mechanical, its range of control is continuous, allowing a far higher level of customization than the jet injectors used today."
  2. I'm a type 1 diabetic by Anonymous Coward · · Score: 5, Interesting

    And they've had "needle-less" injectors around for a long while, however the current ones are expensive and rather inaccurate at dosing when compared to needles.

    However, I must say I really don't care if they come out with a needle-less injector that works better. It's not the shots themselves that bother me, but rather the constant maintenance that people take for granted. I'd still need to do something. Right now I have a pump, and it's better than doing individual injections, but it's always with me. I'm waiting for the day when I no longer have to worry about this disease any longer because I've been cured.

  3. Yes, do you prefer... by Anonymous Coward · · Score: 4, Interesting

    Hypospray, anyone?

  4. Gee! thanks for letting me look at your blog by Emugamer · · Score: 5, Informative

    Someone got his blog pointed at slashdot, while I love the subject, its 4 days old, been on blogs for 3 days and a poor cut and paste job from the original Press release.http://www.berkeley.edu/news/media/release s/2005/03/16_microjet.shtml
    Read the press release, its better :)

  5. The first? by ImTwoSlick · · Score: 4, Interesting
    I have distinct memories of getting shots in basic training, where a needleless gun was used. How is this any different?

    And trust me.. It is not exactly pain-free.

  6. Well beyond... by Faust7 · · Score: 4, Funny

    While they have not yet started tests on humans, the researchers said the range of the injector is well beyond what would be needed to deliver drugs through human skin.

    So for God's sake, ask the nurse to check the settings before she pulls the trigger.

  7. Re:yeah, but will it hit my vein? by Ayaress · · Score: 4, Insightful

    It'll probably only work with injections that go into tissue instead of veins. Accuraccy doesn't matter as much with them, so close enough out to be fine. Also, didn't they already do this some years back? I remember seeing pictures of devices that looked uncomfortably like a pneumatic nail gun that could inject medicine through the skin with pressurized air. Is this just a less sinister-looking version, or did the old one have a habit of giving people embolisms or something?

  8. Needle-free Injection Technology Info by Emugamer · · Score: 4, Informative

    a good page to take a look at is http://www.cdc.gov/nip/dev/jetinject.htm Its the CDC's index to the technology and hasa lot of useful information

  9. pneumatic injectors are painful by johnny+cashed · · Score: 5, Interesting

    I got vaccinated with an "air gun" back in the day. it hurts, probably as much as a needle. But you can do a whole group of people quickly, 'cause you don't need to change needles.

  10. This is nothing new ... by canwaf · · Score: 4, Informative

    Jet injectors have been around since 1940. They were designed to inoculate in Africa, but they kept on jamming because of dust and sand. It was tossed aside for a 3 pronged fork-like needle which you just stabbed someone a couple of times, or scratched them to vaccinate them.

    http://en.wikipedia.org/wiki/Jet_injector

  11. Heroin by yotto · · Score: 4, Funny

    Finally, the last barrier to my upcoming heroin addiction (Fear of needles) has been overcome!

  12. Re:yeah, but will it hit my vein? by Ayaress · · Score: 4, Informative

    Found a picture of one. It's not the one I've seen before, but it was used by the US military back in the 70's, called a Pet-o-Jet. There have also been a lot of patents on them going back into the 50's.

  13. Re:Jetgun by charyou-tree · · Score: 5, Interesting

    Sounds similar to the jetgun the military use to use. Does anyone know the difference?

    Well, they're promising "far less pain" with this device.

    Once upon a time, I had the misfortune to receive a yellow fever vaccination with one of the military's needleless injectors. It felt like some steroid-pumped baseball player had swung a bat at my shoulder. Nearly as bad as the pain was the gathering anticipation of the pain, as I watched the 200-odd people in line ahead of me get their shots.

  14. Its not the needle by dracken · · Score: 4, Informative

    Most people dont realize that the needle itself doesnt sting much. Its the medicine. Some medicines when they come into contact with the flesh inside, sting like crazy. Others dont.

    -Dracken

  15. Injections for Multiple Sclerosis by Anonymous Coward · · Score: 5, Informative

    I was diagnosed with Multiple Sclerosis four years ago (at the age of 22). Then, the best treatment available was Avonex, which is given intramuscularly once a week. The needle is about 26 gauge and 1 1/4" long. With that needle, the pain was mostly psychological. There is nothing natural about stabbing yourself with a long, sharp object.

    In fact, up until about a century ago, sharp objects piercing into your body has generally been a detrimental event. It meant that you were being bitten (with poison or germs getting injected past your outer layer defenses) or you were getting punctured by something that would result in an infection. So everything about your physical makeup and your psychology is evolved to consider injections to be a bad thing. In a twist of events, now it turns out that shard objects getting jabbed into your body is mostly a beneficial thing. But it will take a long time for evolution to change our aversion to injections. And with new technologies, it may not even be necessary for that adaptation to occur. I certainly hope this becomes the case in the *very* near future. :-)

    The nerves on the surface of your skin tend to cluster. So, the amount of pain related to the actual puncture of the skin varies greatly, depending on whether or not you happen to hit one of those nerve clusters. Sometimes the penetration of the skin would result in a strong pinching sensation; other times, I would not feel anything at all. For the intramuscular injections, it is also possible that you will hit another nerve on your way into the muscle tissue. That usually just results in a reflex reaction (you jump or twitch). The act of the actual injection is painless, since the solution is injected far below the surface pain receptors. But then you tend to get long-term dull pain similar to a charly horse; it's like a blunt end of a stick whacked you in the thigh and you have a nice bruise in your muscle. And $deity help you if you happen to hit your bone with the tip of the needle.

    About a year ago, I switched therapies to Rebif, which is given subcutaneously three times a week. The needle is a smaller gauge and is signifianctly shorter (~1.5cm). It is unintuitive, but the subcutaneous injections, even though the needle is shorter and thinner, are much more painful than the IM injections, because the solution is injected just below the surface of the skin, where you have a lot more pain receptors. So it's not the needle really that I worry about. I hardly even feel that any more; it's the stinging sensation from the liquid getting pushed into the subcutaneous tissue just below the skin.

    I use a spring-loaded injection contraption that hides the needle from my view entirely; I just hold the casing to my skin and push a button. The spring-loaded plunger pushes the needle in and presses the plunger of the syringe down to inject the medicine. I don't even worry about the needle any more; I worry about the sting with the liquid getting pushed under my skin and the subsequent itchy and burning red blotch that stays in that area for weeks afterward. So in my case, at least, the needle is a non-issue; this needle-less technology is neat, but it will not help with the pain associated with liquid getting pushed under my skin, and it will not help with the site reaction.

    Wake me up when they figure out how to effectively administrate interferon-beta with a pill.

  16. Injections - no big deal by Andy+Dodd · · Score: 4, Informative

    Thanks to advances in needles, there are insulin injection methods even for those of us that don't pump that are basically painless.

    You probably already know this but many other /.ers don't, but modern insulin needles (at least name-brand ones, if your pharmacy tries to sub in generics you're screwed) are TINY. The Becton Dickinson Ultra-Fine II/III series have almost invisible needles that are short and VERY thin. I rarely ever feel them. (Occasionally I hit a nerve directly - ouch. But most of the time they're not felt at all.)

    Bloodsugar tests are a different story. My fingers are slightly callused from all the pinpricks - There are no real painless and definately no viable noninvasive bloodsugar monitoring techniques. Noninvasive bloodsugar monitoring is probably the second biggest Holy Grail in diabetes research (the biggest being an actual cure). The "alternative site testing" advertised by many modern meter manufacturers is highly overrated. If you read the manual of such meters you'll find that alternative site testing is inaccurate and gives a delayed reading and should not be used in many situations. (Of the 5-6 tests per day I run, only one is in conditions where AST is fine. And for that one test it's not worth changing lancet device heads.)

    The thing I want most as a diabetic right now though is not painless/easier insulin injections (my NovoPen Junior with B-D Ultra-Fine III needles is both painless and convenient), or noninvasive testing (fingersticks are annoying but I'm used to it), it's CHEAP diabetes supplies. Bloodsugar meter test strips run on the order of $0.50-$1 per test. Insulin prices are skyrocketing. You're basically screwed unless you have a high-end medical insurance plan, which is TOUGH when you're a grad student.

    But eventually, an actual cure would be damned nice.

    --
    retrorocket.o not found, launch anyway?