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Study Links Genetic Diseases to Intelligence

FleaPlus writes "The Economist, Sun-Sentinel, and FuturePundit report on a controversial study by Gregory Cochran and others which proposes a link between certain genetic conditions and above-average intelligence in Ashkenazi Jews. The 40-page study, published in the Journal of Biosocial Science, analyzes data on unusual patterns of genetic disease and relates it to a number of intelligence metrics. Although the intelligence data have traditionally been attributed to cultural factors, Cochran proposes that due to the unusual selection pressures the Ashkenazi faced between 800 and 1600AD certain genes developed which promote intelligence as single copies, but lead to particular diseases when somebody inherits two copies. According to Harvard cognitive scientist Steven Pinker, "It would be hard to overstate how politically incorrect this paper is... [though] it's certainly a thorough and well-argued paper, not one that can easily be dismissed outright.""

18 of 689 comments (clear)

  1. Let's see. . . by smooth+wombat · · Score: 5, Interesting
    This paper says that a subset of a religious group is more intelligent due to genetic factors and that's a good thing.

    However, when a paper is presented which says that jews and palestinians are genetically the same, that's a bad thing.

    If the paper had said that this subset of the jewish religion was dumber than others due to genetics would people still have the same reaction or would they have dismissed it as anti-semitic?

    --
    We will bankrupt ourselves in the vain search for absolute security. -- Dwight D. Eisenhower
    1. Re:Let's see. . . by dalutong · · Score: 4, Informative

      It's not a subset of the jewish religion, it is where those jews came from.

      in modern usage, ashkenazis come from europe. Sephardic jews come from the near/middle east.

      the definitions are a little different though. Ashkenazis are, by definitions, supposed to be jews whos family came from germany or eastern europe. sephardics, oddly enough, are supposed to be descended from families from spain or portugal.

      the latter makes a little more sense, though. a lot of iberian jews were expelled during the spanish inquisition. many fled to the near east.

      --

      What comes first, finding a teacher or becoming a student?
    2. Re:Let's see. . . by spiritraveller · · Score: 5, Interesting
      You do have to wonder how much research is never published for fear of a lawsuit....

      How about none, zip, zero.

      In the US there is no basis for suing someone who insults your race or religion. First of all, it's simply not a claim; slander or libel do not apply to huge groups of people. Second of all, the constitution prevents it.

      A French Jewish organization discovered this a few years ago when it sued Yahoo! for selling Nazi paraphernalia. The Jewish group won in the French courts, but Yahoo! had no assets in France. A federal court in the US refused to enforce the French judgment because it said that to do so would violate the First Amendment.

      You still have freedom of speech. Political correctness is just other people reacting to your speech, which they also have the freedom to do. That's not a legal problem per se. It's more of a social and cultural problem.

    3. Re:Let's see. . . by cecille · · Score: 4, Informative

      Challenging that claim would certainly not be incorrect, but I hardly think that's what judaism claims. There are a lot of religions out there that claim to be chosen by god, and while, yes, it does come across as elitist, it is necessary to realize that it is not in reference to a bloodline or genetics, but a way of life. Similar to most religions, Judaism feels that religion brings them closer to god, and by choosing to follow this religion that they become a part of god's people. This isn't something that is only common to Judaism either.

      Yes, it is tracked through the bloodline, but many other religions are also traced this way for the simple fact that people of a certain religion tend to bring up their children to hold their same beliefs. But make no mistake - just because something is passed down through parents does NOT mean that Jewish people claim RACIAL superiority.

      For example, I am jewish, but not by blood...converted when I was quite little, actually. But even without that genetic trace, I've never been treated any differently, and I'm able to participate fully in all of the rites that all jewish people are. It's not a genetics/race thing, it's a beliefs thing, and it's common with a large number of religions.

      --
      ...no two people are not on fire.
  2. Einstein's brain was flawed, too... by Anonymous Coward · · Score: 5, Interesting
    Einstein's brain was actually the product of a genetic defect. From wiki:

    "His brain was preserved in a jar by Dr. Thomas Stoltz Harvey, the pathologist who performed the autopsy on Einstein. Harvey found nothing unusual with his brain, but in 1999 further analysis by a team at McMaster University revealed that his parietal operculum region was missing and, to compensate, his inferior parietal lobe was 15% wider than normal. The inferior parietal region is responsible for mathematical thought, visuospatial cognition, and imagery of movement."

  3. It's possible by udderly · · Score: 5, Interesting

    This is one of those things that drives me crazy. You have people telling us that we're evolved beings and yet on the other hand it's been taboo to even mention the possibility that an isolated group (or groups) of people may have evolved with more or less intelligence.

    I'm not saying that it's that way, but it's definitely within the realm of possibility. But, if you want to get shut down, just mention that you think that it's a possibility.

    Sometimes the truth just is what it is, and not what we want it to be.

  4. Being a Jew ... by your_mother_sews_soc · · Score: 5, Interesting

    This has always been a touchy subject. It does seem that our friends and relatives seem to be pretty smart, but it is something you don't want to raise in public or even among friends, since it smacks of ethnocentrism. But along with the benefits, there seems to be a high prevalence of depression, cancer, and other ills. Whether or not this is true, Hitler, the Moral Majority, and other movements have made it even harder to talk about something sensitive like this that may, in fact, have a scientific basis after all.

    --
    My user name was a mistake. Input wasn't restricted, my bad.
  5. politically incorrect by Turn-X+Alphonse · · Score: 5, Insightful

    Science must never be politically incorrect. It should be the truth, nothing more and nothing less. If you start to use political correct terms you water down the meaning. I'm not going "Say he's a nigger, you know he is", because that's outright wrong, but theres no need to use incorrect terms (AKA African-American if you're not from Africa) to please some minority who seems to think everyone needs a "nice" label and we can't just ignore that people's skin shade can't be controled and means nothing.

    --
    I like muppets.
  6. Politically incorrect, Humbug by BigDogCH · · Score: 5, Insightful

    We could use about 100 more such politically incorrect studies to be published, correct or not Maybe then we can get past the "everyone is equal" and "anyone can achieve anything" crap which has been holding Americas schools back.

    I never did well in art classes, even though I tried harder in that class than others. Other kids just dominated in those classes, yet my teachers claimed that it was all about how hard you worked. Bull Crap! We are each born with a range of potential abilities in each area, and our effort/training determine where in that range we land. We have limits, and we are all different. Some of us just will never be able to draw, and some of us will never be able to handle geometry. Accepting this is critical to helping kids achieve greatness.

    Also, when kids fail or really stink at a content area, we need to let them know that they suck! Instead many people want us to give them empty praise, over inflating their ego. Then, later in life, they find out that they cannot achieve anything, and they are not perfect (their peers will point this out). Soon they can be found plotting harm to their peers, and suffering from depression. Hmmm, could it have something to do with their self-image, which our culture and schools built for them?

    No spelling and grammar neve were my strong suite either. Sorry for becomming slightly off topic, but I hate political correctness.

    1. Re:Politically incorrect, Humbug by Oxygen99 · · Score: 4, Insightful

      Bleh. So we destroy any kids who don't show immediate aptitude for a particular discipline while at school? Oops. Bye-bye Einstein. How about the kids who love art but, in your phraseology, suck? Did you not get any enjoyment from it? You did? But you suck, ergo, no art for you. Yes, you're right, promoting people above their ability is a bad thing, but history is replete with people who didn't show their true colours until later in life.

      Jeez. Slashdot and it's intellectual elitist, reductionism. You've got to love it.

      --
      I had a dream, bright and carefree, but now there's doubt and gravity
    2. Re:Politically incorrect, Humbug by smallpaul · · Score: 4, Interesting

      Maybe then we can get past the "everyone is equal" and "anyone can achieve anything" crap which has been holding Americas schools back.

      I have never met a single person who believes that everyone has exactly the same innate intelligence, musical ability, etc. Everyone knows that different people have different talent.

      Some of us just will never be able to draw, and some of us will never be able to handle geometry. Accepting this is critical to helping kids achieve greatness.

      Sorry, now you're the one spouting bullshit. Of course you may never be able to draw like Leonardo Da Vinci. But with time and effort you can learn to draw to some level better than you do today. Similarly, except for actually disabled children, anyone can learn some geometry. I don't think it is politically correct to point out that the human brain is specifically designed to allow people to acquire new skills and that neither drawing nor geometry are outside the normal range of learnability. Maybe you hate drawing, as I do, and therefore don't want to put in the effort to achieve even minimal skills. Or maybe your teacher taught it incorrectly (I'm told that there is a very good technique for teaching non-drawers to look beyond objects at shapes) but you could learn it if you felt it important.

      I don't find the rest of your rant compelling at all. Most people who are depressed are so because of biochemical imbalances and not because their teachers overpraised them as children.

  7. Re:Dismissed by JaxWeb · · Score: 4, Insightful

    That wasn't the paper, that was an article about the paper. The article is here.

    I think the correlation the author tried to present had two variables that may be related but don't necessarily relate one for one.

    Well it doesn't really matter what you think, because this guy actually researched it. His research is more important than your uninformed opinion. Not saying you're wrong, but I'm saying you don't know, so you cannot dismiss it.

    --
    - Jax
  8. It's all about the measuring stick by DG · · Score: 5, Insightful

    I just finished reading Stephen J Gould's "Mismeasure of Man" http://www.amazon.com/exec/obidos/tg/detail/-/0393 314251/

    which discusses exactly this. Plus I have some real-life experience.

    The biggest problem is that, independant of what point you wish to argue (group X is abnormally intelligent, group Y is sub-par) it's so bloody hard (if not well-nigh impossible) to actually measure intelligence. Even something as simple as measuring brain size turns out to be fraught with difficulties.

    But IQ tests in particular suffer from no end of problems, especially on the lower end of the scale. Did person X score low because they lack intelligence, or because they lack education (not the same thing) or because of other factors.

    I went to a Canadian Military College, which had very high standards of admission. Part of the admissions process was an IQ test of sorts (I don't know if it attempted to generate a classic IQ number, but the questions on it were of the classic "IQ" type)

    As you can imagine, given that 1) I didn't know how much weight this test had on my admission and 2) my whole future depended on getting admitted, taking this test was pretty stressful. I did not do well at all, came close to panic several times during the test, and didn't come close to finishing.

    Happily, I was admitted after all. About a month or two after arriving, we were given the test again. (The local psych department LOVED to give us tests; we were a population tailor-made for testing all sorts of theories) This time, we were told that we were being retested as a way of checking the validity of the test.

    Well after two months of military boot camp, my stress tolerence was much higher. Furthermore, I knew that the results of the test would have no impact on my career. And taking the test was a lot more relaxing than marching around the parade square.

    End result? I aced it. Finished with time to spare. No problem at all. And my peers all reported the same thing.

    Now one could look at the "before" and "after" scores on this test, and conclude that military boot camp raised intelligence, often spectacularly. And you'd be wrong. I and my peers didn't get more intelligent; we got better at handling the stress associated with the test.

    I have serious doubts that intelligence can ever be successfully measured in a rigourous, scientific manner - and that means ANY theory of genetic intelligence, be it high or low, pro or con, can ever be proven out.

    DG

    --
    Want to learn about race cars? Read my Book
  9. Smart Pills by Henry+V+.009 · · Score: 4, Informative

    I'm friends with Cochran. One of his interests is in using this research to find out methods of copying pharmecutically what these genes are doing naturally. (The genetic disease occurs for most of these genes when a person has two copies of the gene. The intelligence advantage comes from just one.) In other words, he wants to create a "smart pill" to raise IQ.

  10. Tay-Sachs != Crippled by Webs+101 · · Score: 5, Informative
    Tay-Sachs does not produce crippled people, so it does not work as you hypothesize.

    The selection would only apply to people who are heterozygous for Tay-Sachs, i.e. they are carriers of the gene. Infants who are born homozygous, with two copies of the gene, only live a few years. All die by age 5. There is no cure.

    So, as you can see, there wouldn't be a whole lot of people crippled with Tay-Sachs running away from the Cossacks....

    --

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  11. The argument in a nutshell by goombah99 · · Score: 4, Interesting
    To answer your question you have to understand the thread of the argument.

    it goes like this. In medieval times jews were not allowed to own land, grow crops, or compete in the labor force. Thus you starved to death and could not support a family unless you are able to work in a management job or as an advisor. In some places, handling loans was considered un-christian and this was relegated to jews. So in other words there was a huge premium of basic survival for above well above average intelligence (that is most people are laborers so to be a manager chosen based on merit--since people did not particularly like jews--you had to have added value not just seniority to be manager.)

    Thus we have an extraordinary selective pressure for intelligence. But this arose over a very short time on human reproductive cycles so nature could not be too selective about picking the best solution from a longevity standpoint. Of course, long term diseases like cancer dont affect reproductive success either. So the Jews got a gene that confers intelligence at the expence of people getting teo of these genes dieing off. Not a bad trade from a speicies point of view. Not so good for 1/4 of the individuals in a gene rich population.

    So you can now see that Palestinian semetics were not subject to this selective pressure precisely because they were not jeweish. Its not the semetic heritage but the jewish religion that was persecuted.

    Okay nice theory but are there other explanations. Perhaps the disease conferred a genetic advantage to some dread disease like say plague. Well first no such disease has been identified. But more significantly, jews were not an isolated population they were integrated into the general population. Therefore the selective pressure of a pathogen would have affected the general population just as much as the jews.

    Okay then what about a founders effect, wherein a population is winnowed down to a few individuals creating a genetic bottleneck in which defects of those individuals are carried into the general population even if they have no benefit. They argue there is no basis for this in the genetic record.

    The selective pressure that differentiated jews from anyone else was cultural.

    Or so the theory goes.

    --
    Some drink at the fountain of knowledge. Others just gargle.
  12. Re:Because something is politically incorrect... by Dammital · · Score: 4, Informative
    When I first saw the name Harvard associated with the quote, I thought "Sure, the politically correct capital of the world". But I thought I'd give Pinker a fair shake.

    Turns out that Pinker was one of the defenders of President Summers' comments concerning gender. From the Harvard Crimson:

    CRIMSON: Were President Summers' remarks within the pale of legitimate academic discourse?

    PINKER: Good grief, shouldn't everything be within the pale of legitimate academic discourse, as long as it is presented with some degree of rigor? That's the difference between a university and a madrassa.

    CRIMSON: Would it be normal to hear a similar set of hypotheses presented and considered at a conference of psychologists?

    PINKER: Some psychologists are still offended by such hypotheses, but yes, they could certainly be considered at most major conferences in scientific psychology.

    CRIMSON: Finally, did you personally find President Summers' remarks (or what you've heard/read of them) to be offensive?

    PINKER: Look, the truth cannot be offensive. Perhaps the hypothesis is wrong, but how would we ever find out whether it is wrong if it is "offensive" even to consider it? People who storm out of a meeting at the mention of a hypothesis, or declare it taboo or offensive without providing arguments or evidence, don't get the concept of a university or free inquiry.

  13. Racial intelligence and Equal Rights by Prien715 · · Score: 5, Insightful

    If genetic group A on average were shown to be generally more intelligent than genetic group B, I don't think this would have huge negative side effects. The problem is that people go from populations to specific instances without a decent grasp of probability.

    For example, light eyed people generally have worse reflexes than darker-eyed people. No baseball recruiter bases their picks on eye-color, they base it on the player's statistics, since it's already factored in. In the same way, if a person from the group with the average lower intelligence got a higher SAT score, higher grades, etc. than someone from the group with "better" genetic intelligence background, the person with the higher scores/grades should to be admitted to college/given the job/etc, just as in the baseball example (note that this decision only depends, like the baseball example, on the desire of the institution to be better, not because of a gov't program or equality concerns).

    Just because a group on average happens to be better than another group, it says nothing determinate about any one member of either group. The group with the lower average intelligence may even have the smartest person as a member and the group with the higher average may the twenty dimmest.

    The only reason a study like this would make a difference this would make is that from a population standpoint, people from one genetic group may have different jobs/salaries/etc than people from another genetic group. While this is trivially true right now, I don't think genetics is necessarily the explaination (or even part thereof). Probably heavily cultural. But how can we know if we don't study it?

    If I say black people are generally taller than Chinese people, that's pretty non-controversial, but any other tests, people are likely to blame the ruler I'm using.

    --
    -- Political fascism requires a Fuhrer.