New MRI Technique Can Detect Diabetes

MonkeyBoy writes "Researchers at Joslin Diabetes Center and Massachusetts General Hospital have unveiled a new magnetic nanoparticle based magnetic resonance imaging technique that can detect diabetes even before clinical symptoms. In mice they were able to take non-invasive images of pancreatic inflammation and its reversal for type 1 diabetes. Full article is available as a PDF from Pubmedcentral. Will we see rapid translation of these pre-clinical observations to prediction and/or stratification of type 1 diabetes and treatment of individuals with the disease? This would provide a crucially needed early predictor of response to therapy. As an added bonus it looks like the analysis was done on a Linux box too."

Comments

One word for this:

[Anonymous Coward]

Sweet!

Linux box

[Anonymous Coward]

This once again proves that the OS is unimportant, and only the application matters. Who cares what OS was used to run the program that allowed this development? Certainly not the patients that benefit from it.

http://www.residentcynic.net/

MRIs gone wild

[sigmaseven]

That's fantastic, but it's going to take a lot of persuasion to get me to go near an MRI willingly after seeing its effect on nearby hospital equipment. You're only as safe as the stupidest person in the room.

Get The Facts

[pin_gween]

I am posting instead of replying b/c there are already several separate posts that have it wrong. Gasp and shock, I know.

Type I diabetes is NOT associated with diet.

This article refers to an autoimmune disease, not a lifestyle induced one.

Re:MRI

[rcolquhoun]

I have heard from several people that have had an MRI that (a) it is almost impossible to get scheduled in any reasonable timeframe for one and (b) they are 'incredibly expensive'.


So is diabetes.

I am a type 1 diabetic and it costs thousands perhaps 10's of thousands per year to manage(if you include side effects, lost opportunities etc). This will be the case for the rest of my life(hopefully 50+ years, although diabetes has a major effect in shortening it).

If it can be prevented by a series of MRI's + drugs or any other treatment for that matter that costs less than say $100k if will be economic for most pre-type 1 patients(ie children) to undertake.

  - Robert

Re:Extremely preminary data

[martalli]

Sometimes, a person's immune system might confuse some viral proteins with the proteins on the pancreatic beta cells (which make insulin). This leads to the immune system attacking the beta cells. Eventually no beta cells are left and a person requires insulin to replace their natural insulin production.

There is nolikely specific infection which causes diabetes. However, some viruses may be more likely to confuse the immune system. Also, your immune system's genetic makeup may predispose it to confusing the virus and the beta cells.

Insulin is required to move glucose from the bloodstream into cells. Without it, the bloodstream glucose level rises until glucose spills out into the urine. In fact, diabetes mellitus is Greek for "sweet urine". Unfortunately, diabetics are literally starving in a sea of food.