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Anxiety Disorders Discoverable by Blood Test
Tomer Yaffe writes to tell us that researchers at the Hebrew University in Jerusalem have discovered a technique to diagnose anxiety disorders with a simple blood test. From the article: "The researchers hope that the anxiety blood test will soon make its way into hospitals and E.R. rooms and give doctors and psychiatrists a quick and precise tool for examining, and eventually treating, these disorders." The team has also set their sights on depression, hoping for a similar technique to detect these types of disorders as well.
then they'd be really screwed..
Stop squirming away from the needle! We need to run this test on you!
As a psych student planning on specializing in anxiety/depression, this is great news. A blood test would make it a lot easier for people to acknowledge that they have an anxiety disorder. Currently one of the greatest challenges a psychologist faces in these disorders is getting the patient to see that they really do have one and it is impacting them negatively.
. . . in that case the test would be fairly conclusive.
Perfect for screening potential employees as well!
My only worry about this is that some people might just be feeling shitty, and wouldn't want to submit to a blood test. What if a person says they're anxious/depressed, but the blood test says otherwise? What do doctors believe?
In any event, it'd probably be better if doctors got to work on making some antidepressants with less overt side effects before they learn to diagnose it...I mean I've just started taking Prozac, and already I'm getting headaches, and the leaflet with the pills has a whole lot more side effects to watch out for.
By summer it was all gone...now shesmovedon. --
I doubt these kind of issues can be singled out by a blood test. I'm sure they are finding some subset of those with an anxiety issue, but they will overlook others with similar issues because "it didn't show up on the test."
The last thing we need are doctors relying even *more* upon tests rather than listening to their patients.
That makes anxiety easy to test for. If there's no blood in the caffeine stream, then they're suffering from excessive anxiety. You can then diagnose the type of anxiety by whether the largest fraction of non-caffeine substance is tea, coffee or chocolate.
It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
For those of you not in the know, Obsessive-Compulsive disorder is an anxiety disorder.
I read TFA.
The problem I see with this kind of testing is the cases where the diagnosed individual refuses treatment. The stigma against being labeled as "crazy" is still crushingly huge, and this is a signifigant reason why many people who suffer from emotional disorders refuse to seek treatment. They see it as a sign of weakness, of "not being able to handle things themselves."
So I forsee and fear individuals getting stuck with a (mandatory) needle then being told, "You are anxious", and "You must submit to treatment". The world knows no shortage of elitist M.D.s who hate the notion of a patient not obeying their very learned whim. Why not use the police to force these people into treatment? Perhaps I'm just being paranoid.
Or maybe I'm just anxious...
I don't make the rules. I just make fun of them.
I disagree. While I feel that recovery should be placed upon the patient, it is important to let them know that they are not responsible for causing the disorder. My significant other was extremely bothered and felt that she was a failure for having an anxiety disorder, but I remind her that "(She) isn't responsible for having the disorder, but she is responsible for her recovery."
Interesting to see that they found a correlation between acetylcholine / acetylcholinesterase and anxiety disorders. It goes to show that the physical symptoms aren't just "in your head". Those two chemicals regulate the nervous system. You'll see that most nerve agents, such as VX, are acetylcholinesterase inhibitors.
I would like to see someone take this new information and conduct another study of the people suffering from Gulf War syndrome - both with physical weakness and mental / anxiety problems. I bet they would discover that many of them were either exposed to a nerve agent or an antidote on some level. It's sad that so many veterans are suffering and our government has made no real effort to help them.
And in my studied opinion, THAT is the most prevalent misconception in the field. Knowing their is a biological component to their illness helps patients realize it's not just them, they aren't just crazy or imagining it, and helps them work on it from a much stronger position.
This is SO educational! -- Kintaro Oe
There was a point, counterpoint and then a reaffirmation of the first point and nobody said the other one was stupid? Is today OPPOSITE DAY!?
It depends on the patient. In my opinion, benzodiazepines should NOT be used for long term treatment (anything longer than 2 weeks or so). What I've observed to be most effective is beginning an SSRI (or in some cases SNRI), and if needed using a benzodiazepine to control the symptoms/side effects until the S(S/N)RI has stablized. Then Cognitive Behavioral Therapy while the patient is on the anti-depressants, and then slowly taking them off of the antidepressants.
Generalized Anxiety Disorder.
I wish this test had been around when I blew my top a few times and ended up in the emergency room. Each visit resulted in a different hypothesis on what was wrong with me, from dehydration to renault's syndrome.
The shit is scary enough when you have no idea what is wrong with you. For most anxiety sufferers, the first half dozen of earthquake sized panic attacks are almost always assumed to be physical problems. I believe I had brain cancer, lung cancer, intestinal cancer, heart problems, etc. Had I been shown a test result that read anxiety, I would have saved a lot of additional anxiety worrying about whether or not my ticker was going to go at any given moment.
Good news.
Perhaps anxious people go to Caffeine as an answer. Then get hooked on harder drugs such as Coding and Linux.
Prozac has changed things but there is this pervasive idea that mood is completely under ones control and that all one needs is determination to snap out of any mood and become the most successful happy person in the world. Happy people tell depressed people naively, "Why don't you just snap out of it?". The problem is is that you can't simulate another persons brain chemistry. You can't even simulate your own brain chemistry from mood to mood. Ever walk by two people yelling and screaming at each other and start thinking, "What's up with them?". Have you ever been those two people yelling and screaming at some point in your life? When we're happy we couldn't imagine how we were sad. When we're sad we couldn't imagine how we could have been happy.
When we eliminate something that wastes the lives of 13% of the population, and if you've ever known someone with an anxiety disorder you'll know how much of their life they waste, won't that improve the human condition more than just about anything else? What's better, is these fixes to mental health improve things throughout society, letting people avoid destructive compulsions and reach their full potential.
Many people (like Tom Cruise) consider psychology to be a pseudoscience. However, if we can come up with definitive tests with concrete results in order to diagnose patients with mental illnesses, it makes psychology that much more closely resemble the rest of the world of medicine. This will (hopefully) make people realize that there is a real science behind it.
I know that if my son was diagnosed with ADD, I would feel much more comfortable having him treated with ritalin or whatever if the doctor had a blood test (or something more concrete than "He's all fidgety in class") to back it up.
Actually, exercise does increase the dopaminergic tone in the brain, the mechanism involved is a short-lived change in gene expression that upregulates calcium transport. It has also been shown to increase the number of dopamine receptors in animal models.
This is relevant because the common mechanism of effect behind SSRI-based antidepressants involves the sensitization of the dopaminergic system via increased serotonin levels. Some antidepressant medication actually has no direct interaction with sertonin at all.
This study shows an effectiveness of 50% of the use of exercise in relieving symptoms of depression, which is approximately that of antidepressant medication or cognitive behavioral therapy alone. Of course, it is likely the best results would come from a combination of all three.
"Fixing" the person is like walpapering a house with collapsed foundations. It'll make the problem invisible... for a while. But unless you fix the foundations, the house will still fall down. Likewise, fixing the foundations alone may prevent further damage, but the inside of the house will still look a wreck.
The job of ANYONE in (or around) mental health is to correct all of the aspects of the mental health problem they are dealing with. A partial solution can be worse than no solution at all, especially if you keep telling the patient that it's all the patient's fault/responsibility.
Establishing a cause, like faulty genes, allows the patient to remedy the underlying problem. Most genetic or biological problems are solvable with the right regemen, but unless you identify those underlying issues, you will NEVER identify the regemen that needs to be followed. And the patient will suffer the consequences of your inaction by deteriorating further. However, such treatment will only ever stabilize a condition. It won't cure it. Curing DOES require the patient to take responsibility for their actions, for their lives and for getting better.
To ask them to take that responsibility whilst their brain is chemically or electically up the spout, though, is about as intelligent as telling the skydiver whose parachute has failed that all they need do is flap their arms faster. Hardware failure requires a hardware solution. Software failure (in this case, the mind of the person) requires a software solution. NEVER assume that hardware will fix faulty software, or software will ever compensate for defective hardware.
Remedy the fault, NOT the fault's owner.
It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
This is 100% correct. I suffer from Paranoid Personality Disorder mixed in with anxiety and there is an inherent component of the "disorder" that would keep you from getting help in the first place. Some number of people with true paranoia or strong enough anxiety would not want to contact anyone for help in the first place. As avoidance, being worried about the interaction, denying any actual problem, etc.
/. back up for Tor!)
Then when you get to taking blood or DNA collection... Jesus. I have enough worries just thinking about medical records, anything written down about me that has the potential to be used against me, especially considering the sorry state of any type of security and the ability of others to gain access to that information through various means.
The paranoid definitely are a group that rarely seeks out "help", this is clear from the DSM and other sources (very few PPD individuals seek treatment compared to other "disorders"), and I can testify first hand that the idea of blood being collected from me, or submitting myself to urine tests or the like certainly is something I would avoid.
(open
Tom Cruise is a typical example of a Scientologist well-treated by that organization because he is a wealthy celebrity. Hubbard himself, in his own writings on Scientology, pointed out that it is important to get as many well known people on board as possible, in order to legitimize Scientology in the public's eyes.
... and we'll read about his suicide. One can always hope.
In any event, Cruise is a fruitcake who should simply get less media time for his outbursts. Sure, you don't want to put somebody on a pill because they had a bad hair day or are just going through a difficult time in their lives. But my father suffered severe clinical depression for the last twenty years of his life, and no amount of imagination and exercise would ever have reversed that. It wasn't until he was put on one of the early antidepressants that he got his life back, and returned to being the father I had always known. People like Cruise should either get medical degrees and learn some facts, or just shut the hell up. God, that man irritates me.
I hope he eventually suffers from clinical depression. We'll see how long it takes him to give up his Scientological "principles" and get on the proper medication. Maybe he won't
The higher the technology, the sharper that two-edged sword.
For example, if I had the money, I would love to finance a study to see how effective relaxation techniques (TM, Yoga, other breathing exercises, exercise...) are in reducing anxiety.
Look at the research of Jon Kabat-Zinn. Here's an example.
Right on! This course of treatment (or rather several courses) has helped me greatly. Cognitive therapy works!! Of course handing a patient a Prozac perscription and a copy of "Feeling Good" is all some health plans will cover. It takes time and the help of a talented person to really make changes in your life.
I wish you well in your studies and your practice.
Typically, a hostile environment will result in the brain chemistry becoming wacked-out. At that point, just altering the environment will no longer be effective - all you're doing is not making the problem worse, but you're not correcting it. However, just treating the brain chemistry won't help either - you'll temporarily fix things, but they'll eventually slide back downhill. You'll constantly have to add more and more of an offset, just to keep pace, and eventually the body will become resistant or die of an overdose.
The correct cure, in such a case, is to remedy the environment (or how the person interacts with it) PLUS medicine to offset the changes to the brain, possibly also some counselling to understand the errors in perception caused by the environment and/or brain chemistry.
What won't help is someone telling you it's all your fault. (If you know better, it's useless information and if you don't, it'll make things worse.) What is needed is not blame but perspective, some sort of solid ground you can aim for, and some plan of action on how to get there.
Another poster suggested I was a scientologist! What a laugh! They've no perspective at all! Anyone who can say that brain chemistry is never an issue is deluding themselves and others. Virtually every experience we have will alter our brain chemistry in some way, and if that way is harmful and becomes semi-permanent - or even permanent - then you will need to take medication to counteract that.
Brain chemistry rarely alters itself (although that does happen), so if you need medicines, there's an excellent chance that you'll need something else to deal with whatever caused the problem in the first place.
Does therapy have a place? Yes - but it's down the list. You might go to a physiotherapist after breaking bones severely in an accident to retrain your coordination. But you wouldn't go until AFTER receiving treatment for your injuries and AFTER your bones are mended. Bleeding to death on the physiotherapist's floor isn't going to help you very much.
ONCE you've got the underlying issues taken care of well enough for you to be able to have perspective (it doesn't have to be perfect, you just have to not be dead) THEN therapy makes sense. If you can't have perspective, all you're doing is wasting time and money. Therapy relies on you wanting to change, but you can't have a want if you aren't in a position to choose.
It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)