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Colds May Trigger Childhood Cancers

Tiger4 writes "BBC News is reporting that the incidence of childhood cancers may be affected by the colds that child has had. From the Article: 'Scientists have found further compelling evidence infections such as colds may trigger childhood cancers. The University of Newcastle-led team looked at 3,000 childhood cancers in 0 to 14-year-olds from 1954 to 1998, the European Journal of Cancer reported. Researchers found unusual clusters of brain tumors and leukemia which were typical of infection-related disease.' As much as an 8 percent increase was observed. However, the article goes on to say that some risks go down with very early exposure to other children, 'In April, a Leukemia Research Fund study found that children introduced to nursery before the age of one were found to be at lower risk of leukemia.'"

5 of 216 comments (clear)

  1. Re:Cause or correlation? by BewireNomali · · Score: 3, Informative

    agreed.... so to the incidence of stomach cancer relative to those who've had ulcers. Ulcers are now known to be caused by h.pylori infections, which are notoriously difficult to eradicate.

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  2. May depends on the virus specie by DrYak · · Score: 4, Informative

    First : The only thing that the article mentions is statistical correlation. As always repeated *THAT* doesn't constitute proof of causality. Experimental proof of the *processus* is necessary before reaching a conclusion, otherwise it may be anything else, including causes due to external 3rd factor (some other /.ers mentionned bad medication, defective immune system or poor socio-economic level. The article itselfs mentions this may depends on genetic factors), or even pure coincidence (this study hasn't been replicated yet).

    Second : There's a lot of virus that can cause cancer. They do this by inserting bogus genetic material into the cell that causes it to replicate, or that disables important anti-cancer genes at the point of insertion.
    Examples of such known viruses includes Human Papilloma Virus, of which some variants (although rarer in the western world) could cause cancer of the woman genitalia (to be precise : the cervix. It's a part of the uterus) and is routinely monitored by the gynecologist.

    Some of these viruses, like the Epstein Barr virus, may only manifest as "colds" or even be asymptomatic, specially in young children (Mononucleosis happens more to older children).
    So, most likely, cancer isn't caused by "common cold" (influenza, RSV, or a bunch of other common viruses and bacteria), but the increased numbers may be explained because some cancer-associated viruses may have "cold"-like symptoms. (Even if the "cancer" variant are rarer in europe than some other parts of the world, as far as I know)

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    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
  3. Re:Cause or correlation? by Cipster · · Score: 4, Informative

    No read the article. It wasn't just a simple correlation, there was also a spatial and temporal association. Pretty much cancer data overlapped with infectious data. Things like weak immune system etc. would lead to constant rates not clustered in both time and space.

  4. Re:Hmm,... by xiao_haozi · · Score: 5, Informative

    Although I do agree with the observation of over-medication in our society (e.g. the abuse of antibiotics and the catalyzed evolution of resistant strains of bacteria), the most likely causation here is from the actual viral infection. The corona virus (i.e. "common cold") has been shown to utilize very unique and distinct replication strategies which may be causing the mutations that would lead to increased susceptibility of tumor develop. As is stated in a later comment in these topic, HPV viral expression patterns have been shown to be linked to almost all cervical cancers. There is most likely some such related mechanism of cellular disruption causing either altered expression patterns in the cells of these children or mutations affecting the proteins that are responsible for regulating cell growth (hence tumor development). What is interesting, however, is that such situations have been shown in adults many times with various viral infections which is logical when one considers the risks of cancer related to age progression.

  5. Re:Hmm,... by Manchot · · Score: 3, Informative

    The thing about science is that your opinion does not change the facts.

    Fact 1: Cancer is caused by mutated cells run amok.
    Fact 2: Over-the-counter pills do not directly change your DNA. They are not overtly carciongenic, and even if they are carcinogenic in large quantities, the effects would take years to manifest. (Think about how long it takes most smokers to get lung cancer.)
    Fact 3: Cold viruses do change your DNA. Just because our bodies are used to fighting off various strains of the common cold, it doesn't make them any less mutagenic to individual cells.

    With these facts in mind, which is most likely to cause cancer? The weak drugs, or the cell-mutating virus? You offer no evidence to support your claim except for your social commentary. That is not science any more than Intelligent Design is.