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Colds May Trigger Childhood Cancers

Tiger4 writes "BBC News is reporting that the incidence of childhood cancers may be affected by the colds that child has had. From the Article: 'Scientists have found further compelling evidence infections such as colds may trigger childhood cancers. The University of Newcastle-led team looked at 3,000 childhood cancers in 0 to 14-year-olds from 1954 to 1998, the European Journal of Cancer reported. Researchers found unusual clusters of brain tumors and leukemia which were typical of infection-related disease.' As much as an 8 percent increase was observed. However, the article goes on to say that some risks go down with very early exposure to other children, 'In April, a Leukemia Research Fund study found that children introduced to nursery before the age of one were found to be at lower risk of leukemia.'"

8 of 216 comments (clear)

  1. Hmm,... by Bill+Wong · · Score: 4, Interesting

    I personally think once more research is done into this, they're going to realize that it's not the colds themselves, but, people overmedicated their children with over the counter pills with doses larger then recommended...

    1. Re:Hmm,... by xiao_haozi · · Score: 5, Informative

      Although I do agree with the observation of over-medication in our society (e.g. the abuse of antibiotics and the catalyzed evolution of resistant strains of bacteria), the most likely causation here is from the actual viral infection. The corona virus (i.e. "common cold") has been shown to utilize very unique and distinct replication strategies which may be causing the mutations that would lead to increased susceptibility of tumor develop. As is stated in a later comment in these topic, HPV viral expression patterns have been shown to be linked to almost all cervical cancers. There is most likely some such related mechanism of cellular disruption causing either altered expression patterns in the cells of these children or mutations affecting the proteins that are responsible for regulating cell growth (hence tumor development). What is interesting, however, is that such situations have been shown in adults many times with various viral infections which is logical when one considers the risks of cancer related to age progression.

  2. Cause or correlation? by drgonzo59 · · Score: 4, Interesting

    Is is also possible that the same children that have a weak immune system and get more colds would also be more susceptable to cancer? So both the colds and the cancer are effects of some other, 3rd cause.

    1. Re:Cause or correlation? by ChrisKnight · · Score: 4, Insightful

      Given that the vast majority of cervical cancer turned out to be a result of HPV infection, it easily falls into the realm of possibility that other cancers have their roots in viral infections, such as colds, as well.

      -Chris

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    2. Re:Cause or correlation? by Cipster · · Score: 4, Informative

      No read the article. It wasn't just a simple correlation, there was also a spatial and temporal association. Pretty much cancer data overlapped with infectious data. Things like weak immune system etc. would lead to constant rates not clustered in both time and space.

  3. May depends on the virus specie by DrYak · · Score: 4, Informative

    First : The only thing that the article mentions is statistical correlation. As always repeated *THAT* doesn't constitute proof of causality. Experimental proof of the *processus* is necessary before reaching a conclusion, otherwise it may be anything else, including causes due to external 3rd factor (some other /.ers mentionned bad medication, defective immune system or poor socio-economic level. The article itselfs mentions this may depends on genetic factors), or even pure coincidence (this study hasn't been replicated yet).

    Second : There's a lot of virus that can cause cancer. They do this by inserting bogus genetic material into the cell that causes it to replicate, or that disables important anti-cancer genes at the point of insertion.
    Examples of such known viruses includes Human Papilloma Virus, of which some variants (although rarer in the western world) could cause cancer of the woman genitalia (to be precise : the cervix. It's a part of the uterus) and is routinely monitored by the gynecologist.

    Some of these viruses, like the Epstein Barr virus, may only manifest as "colds" or even be asymptomatic, specially in young children (Mononucleosis happens more to older children).
    So, most likely, cancer isn't caused by "common cold" (influenza, RSV, or a bunch of other common viruses and bacteria), but the increased numbers may be explained because some cancer-associated viruses may have "cold"-like symptoms. (Even if the "cancer" variant are rarer in europe than some other parts of the world, as far as I know)

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  4. Grossly misinformed! by modecx · · Score: 5, Funny

    Haven't you ever watched TV? The rich never shit or piss!

    They're obviously wealthy enough to have someone do it for them!

    --
    Constitutional rights may be respected, repealed, or modified; but they must never be ignored.
  5. Antibiotics, fungus and cancer by tigerflag · · Score: 5, Interesting

    A number of researchers over the years discovered that what was being called cancer was in fact fungal infections, and tumors were masses of fungal cells. Fungi behave the same way "cancer" does: they change the DNA of their host cells, they cause oxygen-breathing cells to become anaerobic instead, relying on fermentation for their nutrition, etc.

    Antibiotocs kill the beneficial bacteria that keep fungus in check. Cancer rates started to explode after WWII, concurrent with the rise of antibiotic use. It could be that what we're seeing is actually an explosion of fungal infections, but interest in studying and testing for fungus waned as scientists became enthusiastic about studying bacteria, viruses and retroviruses.

    Many people seemingly come down with cancer after experiencing an illness for which they took antibiotics. Since many doctors and parents still insist on giving antibiotics to children with colds, there "could" be a connection. Many illnesses that doctors still give antibiotics for may actually be fungal infections, and the infection remains after the course of antibiotics runs out. Sinus infections come to mind. At least 80% of sinus infections are actually fungal in nature, but the majority of doctors don't test for fungus or prescribe antifungals- they still give antibiotics instead. There are other ways to "catch" a fungus; antibiotics are only one way.

    A number of children with leukemia that develop "secondary" fungal infections have gone into remission as a result of the antifungal medication they received. What if their problem was never cancer in the first place, but was a fungal infection to begin with? If you want more information about this, I HIGHLY recommend a book by Doug Kauffman called "The Germ that Causes Cancer". It has a lot more scientific documentation in it than the cheesy title would indicate.