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Human Genes Still Evolving
MediumFormat writes "The New York Times is running an article that discusses the continuing evolution of human genes. From the article: 'The genes that show this evolutionary change include some responsible for the senses of taste and smell, digestion, bone structure, skin color and brain function.' Darwin Awards aside, what made people think that evolution stopped with the modern era?"
The PLOS biology article is available to everyone via Open Access.
I'll do it for cheesy poofs.
We'll it would have been if it wasn't for this damned webbing between my fingers.
its not that its stopped, its that 5,000 years is an insignificant spec of time.
-ashot
Darwin Awards aside, what made people think that evolution stopped with the modern era?
Applying natural selection as a template, lets look at what it really is. Natural selection is the phenomena of being removed from the gene pool prior to reproduction. Anything else that happens will allow your genes to carry on, which is how evolution works. People probably assumed that evolution stopped because they assume that most people manage to successfully reproduce prior to their death.
Evolution involves the death of weaker individuals before they can breed. With soap (the yardstick of civilisation), surgery, rescue helicopters, dentistry, wheelchairs etc, weaker individuals aren't killed off so easily before they can breed.
Environmentalism is the new Victorianism. Everyone ties on a green corset and pretends we're virtuous.
I think it will be really interesting to see what happens to humanity (genetically) over the next several thousand years. The article makes it sound like bioinformatics could really take off in an effort to better ourselves by artificial selection.
A number of things have changed that will greatly impact our evolution that hasn't been experienced by our species before:
1. Ease of migration allowing for extreme mixing of previously separated social groups (this has been in decline over the last few thousand years, but now that you can travel between continents relatively quickly and cheaply, the impact will be much much greater.)
2. Knowingly allowing, accepting, and encouraging reproduction of individuals, who...shouldn't (No, I don't mean Bush). There's some bad genes out there. Some that shouldn't be passed on. While we're at a point where we can curtail some of this through prescreening parents for likely inherited traits, we continue to become more accepting of people with, well, bad genes. Aren't we effectively letting people piss into the pool?
3. Will this spawn a new race (as in car) by parents to "maximize" the brain genes described in TFA? Do I have to listen to soccer mom's brag about their kids DNA now?
4. How will this impact governments? And more importantly, dating websites?
I guess only time will tell.
I mean really? Come on...
You go to college, work your arse off, earn lots of money, die without kids, the race doesn't get your genes. You're a single parent living on state benefit with 12 kids... big contribution to the gene pool.
Deleted
Yesterday, I read this in the Guardian. It's a very interesting article about how, over the last 10.000 years, our DNA has been altered by what we eat and where we live.
42 + 1 = 42
I hate to see all these comments talking about how evolution mechanisms are failing in the modern world.
We can't escape natural selection, no matter how many pills and safety mechanisms we introduce into society.
Women just tend to become more and more picky with whom they mate. And while things like good eye sight become less important, other things take their place. Things like having lots of money, social skills/social network, an athletic body, cooking skills and so on.
Here in Europe, the number of babies born per adult keep falling. This means it is actually getting harder to reproduce than it was in a past, poorer Europe.
Will code a sig generator for food
- the humane genes are still evolving
- they are evolving at a rapid rate
- they are evolving in the wrong direction
Oh yeah, and:
- it's not 'designed'
- it's certainly not 'intelligent'
Of course human genes are still evolving; you just have to examine what it is these days that limits people in reproductivity, and what encourages them. It's obvious that we, as a species, should ever so slightly more alcohol-resistant, because drunk driving kills a lot of young people before they can reproduce.
Humans of European ancestory are already more resistant to alchol than most mammals. Because for a long time brewing was the normal method of purifying drinking water. Cars have only been around for just over a century, where as water living pathogens have been around a lot longer.
An evolutionary advantage is whatever passes your genes on to the next generation. Hence it is the poor not the rich that have it. Quality of life doesn't make a difference. Evolution is a simple dumb process, it holds no moral judgements whatsoever.
James P. Barrett
Bullshit. Culture has never been a static, unchanging entity. Culture is whatever we as a society wish it to be, and it changes all the time.
Indeed, science has had an amazing impact on culture in the last 100 years. We moved from a culture of travel by foot and horse to an automotive culture. We've gone from Uncle George playing a banjo to carrying whatever music we want wherever we want on portable music devices. We've gone from having to spend hours at the library to look up an obscure fact to having information at our fingertips 24 hours a day. We've gone from candles and oil lamps to electric lights. And perhaps most noticably, we've gone from getting together with friends and family, or reading a book, or playing a board game, to sitting in front of the TV set.
Sorry, but our culture is very heavily influenced by science. It wasn't that long ago in certain parts of the Western world where the area you were allowed to sit in on the bus was determined by the colour of your skin -- something which is no longer part of any Western culture (except in the minds of a few deluded racists who think that culture is static and unchanging, so long as they get to dictate what culture is).
Yes, some parts of culture are sufficiently ingrained that it is hard to overcome their momentum -- but it is hardly impossible to do so. Major events and new ideas and inventions are changing culture every day.
I'm sure 10+ years ago there were some old white guys in South Africa who were convinced that Apartheid would never end as well -- and yet here we are. Women are allowed to vote everywhere in the Westernized world as well, in case nobody had bothered to tell you.
Sorry, but you come across as an appologist for racists and bigots with a dumb comment like that. Culture changes. Get used to it. Discrimination is not a given -- it's a completely learned trait
Yaz.
This is a very good point that quite a lot of people don't seem to get. Anything that causes a person not to reproduce is (eventually) selected against. For example, being sensitive to the meme "there are too many people on this world" is an evolutionary disadvantage and will eventually be removed from the genepool. The same goes for high intelligence (being that intelligent people often don't reproduce).
:)
That's probably also why religion is so prevalent in human populations: the evolutionary advantage it gives should not be underestimated.
So if you consider people like you to be a good addition to the human gene pool, breed!
Error: password can't contain reverse spelling of ancient Chinese emperor
Some people lead long, healthy active lives and never reproduce through choice, lack of opportunity or possibly just inadequate social skills. Isaac Newton famously died a virgin.
Precisely. And yet Newton undoubtedly had an effect on the general society around him, not least through his work in the mint. The overall population benefited from his labours, although he never himself returned his genes to the general pool.
Lets say, as is generally thought, that Newton had genes which gave him an extreme "geek" factor. This factor benefits the general populace, although the "geek" genes themselves may never be passed on directly. However, the potential for such genes to be expressed is passed on through, for example, Newton's siblings and close relatives.
Evolution works on a macro population level, not just on an individual organisim by organism basis.
May the Maths Be with you!
Most whites have a gene that gives partial resistance to Bubonic Plague, as those Europeans who didn't have it 600 years ago don't have living descendants now.
Will the next big evolutionary change be (partial?) resistance to Bird-flu or Ebola ?
Quidquid Latine dictum sit, altum videtur (anything said in Latin sounds important)
While we're at a point where we can curtail some of this through prescreening parents for likely inherited traits, we continue to become more accepting of people with, well, bad genes. Aren't we effectively letting people piss into the pool?
No. No. No. Eugenics is not just wrong. It's painfully stupid.
Why does evolution work? What is the secret. The secret my friends is randomness.
Randomness is the process which drives evolution. The universe is a vast, unpredicable chaotic system. It is only by randomly searching through many possible solutions that a species can hope to adapt to any enviornment.
The minute you take out randomness, by taking away genes or introducing them, you've stopped evolving, and have started specialising. And guess what happens to specialist species when their enviornment changes? That's right. They die.
Evolve dolphins with bigger lungs so they can dive deeper, kill off all lesser lunged dolphins. Then earths 02 levels drop by 2%. Ooops. Specialised, deep sea feeding dolphins are dead meat. With a random system, there would still be some lower lung capacity dolphins around.
Think this doesn't apply to people? Ask yourself this? Can you say with certainty what genes will be beneficial or detrimental to humanities survival in 1 million years time? What about 10,00 years time? 100 years? 10 years? Who would have predicted even 20 years ago that "geek" traits would be in such demand? Can you say what genes are beneficial or detrimental right now!?
Yet you want to throw out the single most powerful aspect of evolution. Random chance. It's got us where we are today, and if you think anyone can engineer an entire planet and its ecosystem half as well as random evolution, I'd like to see you try.
For an example of the superiority of evolution over engineering, just check out evolved antennas. NASA seems to think random evolution is just fine.
May the Maths Be with you!
Lets put it this way, humans are not going to ever loose their pinky finger if modern society goes on the way it is.
I don't think you can expect any MAJOR changes in an evolutionary model that does not ELIMINATE unfavorable characterists. We live in society's in which pretty much everybody reproduces and most of those reproductions end up reproducing themself. For those who cannot cope with society, we have public assistance and jail.
If anything, I believe modern evolutionary pressure (the last three hundred years) is producing more of the genes from people who have poor family planning skills and just cannot grasp or accept birth control. I fear what this pattern may produce in 20,000 years where people with less cognitive skills have 3-4 times more children than those with more cognitive skills. That and the other pressure for religious fanatics to have more children than those who take rational views of the world. Those with deep intellect could be forced to create a "Zardoz" society to protect themselves.
-------- -------- Support Wesley Clark for president!!!
>>Genetically, we have a concept called races.
G enetics
e
>No, we don't. Race is cultural, and is of little interest genetically.
Really? Explain that to my black friend in 8th grade as he suffered during a sickle-cell anemia crisis.
I'm sure he'd be happy to know that he can't have a disease that affects primarily African-Americans, because there are no genetic differences in races.
http://en.wikipedia.org/wiki/Sickle-cell_disease#
Or to my Chinese roommate who lacks alcohol dehydrogenase enzymes in his liver and so has one drink and turns bright red. Embarassing for a guy who was in a frat that prized heavy drinking skills very highly. The enzyme deficiency has a huge penetration in Asia, something like up to 70% in some countries, a couple percent in Germany, 0% in Ireland. Go figure.
http://en.wikipedia.org/wiki/Alcohol_dehydrogenas
Or the Jewish student organization that sponsored a free screening day for Tay-Sachs.
http://en.wikipedia.org/wiki/Tay-Sachs_disease
The concept that race is solely a cultural construct is mere wishful thinking: "I wish there were no genetic differences in people, because then there'd be no racism, and we'd all live in a world filled with flowers and ponies." No, as we discover more about genetic diversity we learn which genes have greater tendencies in certain ethnic groups. This is NOT an excuse for racism -- the concept that one person can be somehow metaphysically superior than another due to skin pigmentation is absurd -- but denying uncontroversial science for political reasons is troubling as well.
But what's in the DNA doesn't correlate particularly well with what we have culturally labelled 'races'. The genetic difference between a European, an Arab, an Indian, a Chinaman, an aboriginal, and a native American isn't all that much, compared to the genetic difference between African tribe A and African tribe B. And yet we consider David Smith and Tanaka Jiro to be of different 'races', while two Africans of far greater genetic diversity from each other we lump together as 'black'.
Real Daleks don't climb stairs - they level the building.
But who would you say is intelligent? It seems to me like you are confusing making a carreer for yourself with beeing genetically superior in terms of intelligence.
How many great minds are not being spent looking for food on garbage dumps in Africa? Or go their whole life without ever getting access to even basic education? If you examine the phd's of the world and compare their genes to the genes of the homeless, it would be very surprising if you found any regular difference.
Genetically, you are not in any way inferior because you spend your days trying to survive starvation, or flip burgers for minimum-wage at McDonalds.
What many people fail to realize is that it takes "evolution" on the order of tens to hundreds thousands of years to "invent" a gene.
Random mutations have to encode for a new protein that activates in the right cells and "does the right thing". From then on, this is likely to become a "gene": Almost any random mutation will invalidate the protein, and disable the "feature".
Suppose such a new "invention" is not always advantageous. Say, only during an ice age. During ice ages, those carrying the intact encoding for the protein (we say they "have the gene"), will survive best, those that don't have it will drop in numbers. Once such a condition is over (say ice age stops), natural selection suddely starts to favor those that "do not have the gene". Still, as they decend from a population where most had the gene to survive, they remain "genetically close", and the gene will easily activate and proliferate during the next ice age.
A real world example is Sicle Cell Anemia. It is a genetic disease: You're born with or without it. Advantage of HAVING the disease? You don't die of Malaria (you do die of the disease, but most have had children by then).
So depending on the amount of malaria mosquitos around, the percentage of people with the Sicle Cell Anemia gene varies a lot. Natural selection at work!
Now, if you look at 10000 to 15000 years, it is unlikely that "evolution" has "invented" a lot of new genes. That however genes have activated and deactivated is however very likely.
If the "running fast" gene was "mostly essential" 10000 years ago in africa, but now not any more, then natural selection would have ensured that 90-95% of the population had that gene 10000 years ago. Nowadays, there is no longer a selection for-or-against this gene. So, the percentage of the people having the gene will slowly drop (I don't work in the field, I have no idea how fast this goes).
Did you ever notice that different children "don't like" different foods? This is a genetic safeguard to preserve the species. Evolution apparently "invented" that a long time ago.
If five percent of your tribe "Simply doesn't like to eat chicken", and the H5N1 Chicken flue comes around, about 5% of the tribe is likely to survive to pass on a much elevated "don't like chicken" gene.
Most likely the "common knowledge" about what to eat and what not to eat has leveled out the "taste" genes: They no longer significantly influence survival.
If you end Aparthied in South Africa you simply are creating a new form of Aparthied somewhere else.
Of course. I'd forgotten the law of conservation of Apartheid.
My Karma: ran over your Dogma
StrawberryFrog
No, it can only be selected if there is genetic differentiation in it. So if susceptibility levels to the "full world" meme vary for different alleles of the same gene, the less susceptible versions will be selected for. But if that genetic variation doesn't exist, it can't be selected for.
It works the other way round, too. Anything that has evolved has clearly been subject to inheritable differences in the past, and it probably still is, unless the selective pressure for it is so strong that the population is essentially homeogenous. This is the strongest argument for there being a genetic basis to intelligence level, since intelligence has clearly evolved in the fairly recent past.
Holy crap! They were missing four fingers and toes and some sick bastard amputated the ones they had?!
It is a conceit of the intelligent that intelligence drives human evolution. The skeletons of early hominids show evidence of the support of unproductive individuals within communities. Skeletons with broken but healed limbs, crippling arthritis, debilitating head wounds show that individuals that had been injured or were elderly were cared for by their peers/relations. The intelligent thing to do would be to ditch the dead weight and ease pressure on resources. Instead the human attributes demonstrated are compassion and co-operation. As for man getting less-healthy, no-one can tell which genes will be be favoured by the whims of nature and the wider the gene pool the better. In Europe sickle cell anaemia is an illness, in malarial zones it's an eveolutionary adaptation that aids survival. Who is to say what's healthy and what isn't. We have survived and prospered through our abilities to communicate and co-operate. Intelligence has followed on the coattails of our advancement and has not driven it. If a near-extinction meteor impact were to occur, would the species' best hope of survival lie with a select group of the Intelligensia or a select group of fertile people with excellent parenting skills? Think on this: You, dear reader, may regard yourself as intelligent and may pride yourself on your ability to read PERL or code in binary but that doesn't make babies. It is true that the "intelligent" breed less. The brutal fact is the geekier you are the less likely you are to reproduce and so when you have finished that algol compiler you've been working on and want to pat yourself on the back for being clever, remind yourself that you are not the pinnacle of human evolution and just an offshoot. The single mother successfully stretching out her budget raising four kids is more likely to leave an indelible imprint on the evolution of Man than you are.
Travelling forward in time at a rate of 1 second per second.
My father was slaughtered by a six-fingered man. He was a great swordmaker, my father. When the six-fingered man appeared and requested a special sword. My father took the job. He slaved a year before it was done. The six-fingered man returned and demanded it, but at one tenth his promised price, my father refused. Without a word, the six-fingered man slashed him through the heart. I loved my father. So naturally, I challenged his murderer to a duel. I failed. The six-fingered man left me alive, but he gave me these. I was eleven years old. And when I was strong enough, I dedicated my life to the study of fencing. So the next time we meet, I will not fail. I will go up to the six-fingered man and say, "Hello. My name is Inigo Montoya. You killed my father. Prepare to die."
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