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Coffee Maybe Not a Health Drink!

perbert writes "Canadian researchers have published a study in the Journal of the American Medical Association indicating that excess coffee drinking (4+ cups a day) could lead to an increased risk of heart disease if you have the wrong gene. In light of other studies linking antioxidants in coffee to a reduction in heart disease, who is right? Or will they cancel out in a coffee death-match?"

30 of 381 comments (clear)

  1. Dose by ThenAgain · · Score: 5, Insightful

    As with anything related to toxicology, the dose is the poison.

    1. Re:Dose by AKAImBatman · · Score: 4, Insightful

      In other words, keep it to a cup or two a day and you'll be fine. You may even reap the benefits of Coffee's antioxidants.

      If anyone ever tells you to do a lot of anything, run the other way. People have died from everything from eating too much salt to drinking too much carrot juice. Keep your diet balanced and your intakes in moderation, and you'll do far better than chasing around massive doses of things that are "good" for you.

    2. Re:Dose by ergo98 · · Score: 5, Interesting

      As with anything related to toxicology, the dose is the poison.

      To a point, however that simplifies and misses the point of the article: The researchers are claiming that there are two common variants of the gene responsible for the systems that breaks down coffee, and those with one variant are made healthier by 3 cups of coffee a day, while those with the other variant (CYP1A2*1F) are detrimentally affected by the same.

      So it's the dose...and the genes that build the systems that deal with the dose.

    3. Re:Dose by Alex+P+Keaton+in+da · · Score: 5, Interesting

      Also, as with anything else, direct causation is almost impossible to prove. 4+ cups of coffee leads to heart disease? I would postulate, not from scientific study but from anecdotal evidence gathered over years of stressful jobs, that the people under the most pressure and stress tend to drink the most coffee. So maybe the stress is what is causing the heart disease?
      Also, coffee is so acidic that people who work out everyday are not likely to be able to drink 4+ cups a day (again, non scientific anecdotal evidence). Coffee is currently fashionable, but when I think of a stereotypical coffee addict like myslelf, I dont think of a slim trim health nut...

      --
      And All I Ask is a Tall Ship And a Star to Steer Her By
    4. Re:Dose by gunnk · · Score: 4, Informative

      ... and even drinking to much water. That's actually been a problem for several years now at marathons, half-marathons and other road races. People tend to drink at every water station. That lowers their electrolytes to the point they require medical help. It's actually much more common now than people dehydrating during races.

      --
      Life is short: void the warranty.
    5. Re:Dose by 0NoQuarter14 · · Score: 4, Funny

      If anyone ever tells you to do a lot of anything, run the other way.

      But don't run too far.

  2. Paracelso once said... by Zaatxe · · Score: 4, Insightful

    "the difference between medication and poison is the dose"

    --
    So say we all
  3. here we go again by dkode · · Score: 5, Interesting

    More and more often I keep hearing about things like this.

    "Doctors say more than 4 cups is bad for you!"

    then, 2 months later... "Doctors say more than 4 cups is good for you!"

    One month you hear too much fiber is bad for you, then cholesterol is good for you.

    I think as long as everyone comsumes food/drinks moderately and not go over board most people have nothing to worry about. Although, with obesity in the United States the way it is today, I would say it's already too late.

    --

    Those who trade in their freedom for security, deserve neither.
  4. Well, by deletedaccount · · Score: 5, Funny

    I've started injecting it, so I'm not sure how this applies to me.

  5. To quote a much more sensible man than me ... by SpooForBrains · · Score: 4, Funny

    ... namely one Commander Samuel Vimes: "Coffee is merely a way of stealing time that by rights should belong to your slightly older self".

    --
    "The dew has clearly fallen with a particularly sickening thud this morning"
  6. The coffee dilemma; a management perspective by dcavanaugh · · Score: 4, Funny

    Health hazard or health drink? What to do? The answer is simple. Find studies that support your pre-determined point of view and use those to guide the decision. I like coffee very much. Caffeine addiction is not a problem so long as I can find at least one study that proves how healthy my coffee habit is.

    Now back to our regularly scheduled programming, "TCO analysis for the enterprise"

  7. Ex Caffeine Junky by garcia · · Score: 5, Interesting

    I was basically forced to quit drinking caffeine in Decemeber. This was not something I ever expected to be able to do. The migraine lasted for about a week straight but I have been basically fine since.

    Since I was 22 I have had high blood pressure. I've spoken here about it before and complained about the high cost of Rx meds to control it and my belief that my Doctor (undercompensated by my insurance provider) is possibly pushing name-brand drugs instead of their generic counterparts to recoup some of that cost in kick-backs.

    Anyway, I was gaining on 200mg daily of various meds to control the BP. I was also gaining in daily consumption of caffeine. After switching to Diet Cherry Vanilla Dr. Pepper (aka Liquid Crack) I was heading for 5 to 6 20oz bottles a day (at work) plus 5 to 10 12oz cans every two days (at home).

    After quitting the caffeine habbit I'm on 10mg of BP meds (about $10 a month) and water.

    So, if you're looking to limit your heart disease and the high cost of protecting yourself against it with prescriptions, you might want to first take a look at your caffeine intake. It worked for me.

  8. In other news... by BecomingLumberg · · Score: 4, Funny
    In other news, drinking/eating too much of $SUBSTANCE could lead to $HEALTH.PROBLEM.

    --
    If a nation expects to be ignorant and free, in a state of civilization, it expects what never was and never will be.-TJ
  9. What does this mean... by dantheman82 · · Score: 5, Funny

    for the future of Java? For now, I'm drinking green tea and coding in C#.

    --
    This sig donated to Pater. Long live /.
  10. You Misunderstand by Makarakalax · · Score: 5, Insightful

    What happens is that conflicting summaries get posted around the Internet and everyone thinks scientists are just having them on.

    If you look carefully the summary for the research is saying the caffeine is bad for you, and that the study concluded this based on research into coffee consumption. The other studies that claim coffee is good for you were actually referring to other chemicals in coffee, not the caffeine, nor the entirety of the coffee.

    Also people seem to think that scientists study everything about a topic before releasing results. But that is a misunderstanding about how science works. Generally scientists focus on very small areas of large topics and then propose more sweeping conclusions. Usually the media then make even more generalised conclusions that result in complete misunderstanding in non-scientists.

    Peer review is also important, often these studies are fundamentally flawed and even though the submitted paper offers a conclusion, the scientist writing it is well aware that in science, nothing is proved by one paper. Instead wait ten years for more supporting evidence, rinse, repeat and progress.

  11. Re:Who Cares by TripMaster+Monkey · · Score: 5, Funny

    It is by coffee alone I set my mind in motion.
    It is by the juice of the java bean that thoughts acquire speed.
    The teeth acquire stains; the stains become a warning.
    It is by coffee alone I set my mind in motion.
    Apologies to Frank Herbert.
    --
    ____

    ~ |rip/\/\aster /\/\onkey

  12. Studies have shown... by Anonymous Coward · · Score: 5, Funny

    "Studies have shown that research causes cancer in lab rats."

  13. Totally offtopic about your signature by fistfullast33l · · Score: 5, Funny
    while ($beer != full) { $beer = new Beer(); chug($beer); }

    So here's a small problem with your signature - you run the while loop until the beer is full...but you chug the beer inside the while loop. Which means that once your beer is full...you stop drinking. Of course, this is all dependent upon the fact that chug doesn't empty the glass, which is usually what happens when you chug...so basically I think you need to check the return of chug to make sure it didn't fail. Otherwise you might have problems.

    Sorry for wasting your time.

    1. Re:Totally offtopic about your signature by flooey · · Score: 4, Funny

      In re-reading this I'm coming to terms with the fact that maybe I need to GET A LIFE!

      Or a beer.

  14. Fittingly Canadian Story by slashbob22 · · Score: 4, Interesting

    I can only laugh as I sip on my Large Double-Double[1] Coffee from Tim Hortons. Coffee can kill me, my Work may kill me, walking across the street is dangerous. On the plus side, the coffee helps me cope at work and keeps me alert as I walk across the street: reducing 2 out of 3 risks isn't too bad.

    [1] For those not in the know: double-double -- a coffee with double cream, double sugar (especially, but not exclusively, from Tim Hortons). http://en.wikipedia.org/wiki/Canadian_slang

    --
    Proof by very large bribes. QED.
  15. please read more carefully in the future by raygundan · · Score: 5, Insightful

    Blame the media's lousy science reporting or poor reading comprehension skills, but what people see as conflicting results are often nothing of the kind, they just miss the details.

    I saw one study that said a single cup of coffee a day was good for athletic training, and another that said that the more coffee you drink, the lower the risk of heart disease.

    This study says that more than four cups of coffee a day are bad for you if you have a particular gene.

    None of these things are contradictory-- just like how a glass of wine may be beneficial, but 10 glasses may cause liver disease. Or how some types of cholesterol are good, but others are bad.

  16. Coffee by Himring · · Score: 4, Funny

    I quit all other drugs in my life. The only thing I have left is coffee. They can take it when they pry it from my cold (well, warmed), dead fingers. I started drinking it in college and fell in love. It's the right way to start a morning. It doesn't offend with its smell like tobacco. It doesn't impair driving like alcohol. It is the primordial source of gathering in the break room. It is the basis for the original Terry Tate, Office Linebacker skit. It gives cops something to hold along with a donut. It provided cease fires during the Civil War as the south traded tobacco for coffee with the north. It is the foundation of eclectic, bohemian establishments wherein college kids make it, and other college kids drink it (coffee shops) and also birthed some of the first public access to the Internet outside of libraries. It is a primary staple product in many South American countries. It's something that (according to my systematics professor) the English don't make very well. It revs you up before anything you need revving up for. I use it before my workout too. It is best when freshly ground and french-pressed. It has created many wonderful cups that say things on them. It gives dentists something to clean during checkups. Wtf beat it up? Study says this/study says that.

    Next: water -- a study shows too much of it can make your lungs stop producing needful oxygen....

    --
    "All great things are simple & expressed in a single word: freedom, justice, honor, duty, mercy, hope." --Churchill
  17. Time for a bigger cup by Helmholtz · · Score: 4, Funny

    Since it's the number of cups that makes a difference, I guess I just need to switch to a bigger cup .....

    --
    RFC2119
  18. Re:Everything in Moderation by Anonymous Coward · · Score: 4, Informative

    Your symptoms (rapid pulse, dizziness) could be an adrenergic response to hypoglycemia.

    When this happens, do you experience difficulty concentrating? (Neuroglycopenia) And does it subsequently go away when you ingest food, especially sugar? Do you experience frequent urination during the recovery phase? If it's Hypoglycemia, it is actually very dangerous for your brain.

    Caffeine's kick comes from its ability to expedite the transport of sugar from the blood to the tissues. The occasionally dangerous side effect is that if you have a problem with your diet and/or anrednal glands, since caffeine creates this metabolic illusion of an energy boost, the combination can sometimes result in depleting the blood of sugar faster than this sugar can be replenished. Then you crash dangerously hard, experiencing what insulin-dependent diabetics refer to as a "hypo."

    When your brain detects low blood sugar, it triggers the release of adrenalin and cortisol which are stress hormones, and this causes your body to release emergency sugar from other sources, such as stored glucagon from your liver.

    So most of the unpleasant effects of hypoglycemia are actually your body's defense against it. But you are 100% right to avoid coffee if it does that to you, since this is a warning sign. Coffee does not do this to everybody.

    Whatever the problem is, things can likely be brought back into balance just by eating moderate balanced meals, and having healthy snacks between meals and before bed. If you eat a lot of sugar, take it with some protein and/or fat so that your pancreas never gets habitually braced for dealing with big jolts of sugar... because it'll get itself into a mode where it produces too much insulin at the wrong time... which can be as dangerous as the legendary diabetic insulin overdose. So ironically, too much sugar can cause hypoglycemia.

    Definitely talk to a Dietician.

    Possibly at some point in the future, you might consult an Endocrinologist if you've been bingeing on high-sugar foods, and you think you might be at risk of developing type II diabetes or something like hyperinsulinism or hypoglycemia. (The latter two may actually be somewhat common. It's the diagnosis for them which is exceedingly rare, since they are both very difficult to get clinically diagnosed. Pretty much only the textbook cases that present under ideal circumstances will ever get diagnosed.) You almost have to be pretty sick before an Endocrinologist will be able to help you.

    Good luck...

    PS:
    I personally had just one episode of "reactive hypoglycemia" involving just one strong coffee, a skipped breakfast and some physical exertion, and it felt exactly like the experiences you describe having with coffee. I did not lose consciousness, but the experience did leave me with some very subtle brain damage... (which I seem to be adapting to finally after 6 weeks.)

  19. Re:Aspartame by Anonymous Coward · · Score: 4, Informative

    Your dietician needs to go back to med school. Yes, aspartame breaks down to formadehyde as the tail end of the process of your small intestine converting it to methanol. Formaldehyde (from methanol) is a normal chemical to be found in your body as a normal byproduct of normal digestion.

    The amount of methanol produced by Aspartame in the body is 10% of the ingested aspartame. Assuming all the methonal is further converted to formadehyde, a normal 12 oz soft drink causes only 1/6th the amount of methonal production as an equivalent drink of Tomato Juice (which contains no Aspartame, but contains other "natural" chemicals that produce methanol).

    The actual numbers are this:

    A 12 oz diet soda contains 225 mg of Aspartame (approximately 0.05% of the drink is aspartame). That generates 22.5 mg of methanol, or about 0.005% of the drink will become methanol. We will assume all the methanol becomes formaldehyde (worst case). The LD50 of formaldehyde is 100mg/kg. For an average male of 75 kg, that would mean 7500mg. A total of 333 sodas must be drank by this average male to assure death, and they must be drank fast enough to counteract the body's natural ability to rid itself of formaldehyde.

    Of course, hyponatremia will set in, without exercise or dry heat, with drinking about 3 or more litres of fluid per hour, for serveral hours straight. 333 sodas will contain 3996 oz of liquid, or about 118 litres. Anyone attempting death through ingestion of Aspartame by soda comsumption will surely die of hyponatremia far before they have reached even small amount of their goal!

    Feel free to ask your dietician to verify this!

  20. Warning: This May Be Harmful To Your Health by ackthpt · · Score: 5, Funny
    "Coffee Maybe Not a Health Drink!" Gasp! :-)

    From a life-long geek's perspective:

    • I've sat for hours, for years in front of 25" colour TVs before they reduced radiation emissions.
    • I've eaten countless bags of crisps flavoured with chemicals for visual and taste enhancements and dusted with MSG
    • I've eaten countless pounds of fried foods
    • I've made my share of /. typos (inadvertent and purposful)
    • I've raced on a bicycle over 60 MPH downhill
    • I've been hit with kilovolt shocks
    • I attended dozens of indoors Hamfests, choked with the smog of hundreds of cigarettes, plus a few pipes and cigars.
    • I've been run over by a car
    • I've drunk a Mickey's Bigmouth
    • I flew on a jet that bounced on the runway at Baltimore
    • I fell out of a raft in the middle of Lost Paddle class V rapids in the Upper Gauley river of West Virginia
    • I've collided with my brother's sled on an icy hill in Michigan, nearly fracturing my skull.
    • I've been in 3 auto accidents
    • I've lept off a 40 foot cliff into a flooded quarry
      • I'm not done yet.

        Regarding health, it will be bad for someone's if I don't get my coffee.

    --

    A feeling of having made the same mistake before: Deja Foobar
  21. Re:best not to have any coffee by flyingsquid · · Score: 4, Interesting
    As with all addictive substances, it's best not to become addicted. Two cups a day means you are addicted. If you "need" a cup a day, you are addicted.

    It's not like it's freakin' heroin or something. First of all, you're probably better off being a "hard-core" coffee addict than a casual user of cocaine or heroin. Second, last time I checked there weren't any twelve-step programs for coffee drinkers, or patches to help them quit. That suggests that either people don't have a problem with being regular coffee drinkers, and/or they don't have much of a problem quitting if it's making them irritable, sleepless or whatever.

    The whole "addiction" thing is just a little out of hand. When I'm working out in the desert I may drink two liters of water a day, and damn sure I feel a "need" for water when its 90 degrees. So I'm a water addict? To be an addiction, I think it has to (a) be seriously detrimental to your well-being, and (b) you have to have serious trouble quitting. Coffee doesn't meet either of those criteria.

  22. Who funded the study? by deviantphil · · Score: 5, Insightful

    A lot of who is right depends on who funded each study and what they set out to prove (or disprove) in their study.

  23. Re:Who Cares by Scarblac · · Score: 4, Funny

    I must drink coffee. It is the mind filler. It is the little shot that brings total caffeination. I will taste my coffee. I will allow it to pass through me. And when it has gone past I will turn the inner eye to see its path. Where the coffee has gone there will be nothing. Only I will remain. Then I must drink more coffee. It is the mind filler...

    --
    I believe posters are recognized by their sig. So I made one.
  24. Re:best not to have any coffee by Hatta · · Score: 4, Insightful

    Open your mind, most junkies are just normal people who made some bad choices. Given that we can't stop them from using, we may as well try to minimize the damage those choices inflict.

    Opiates to build tolerance on their own, so said legal junky will still need more and more.

    People on heroin maintenance programs tend to acclimate to a dosing schedule that keeps them functional. They're so tolerant that they literally can't get enough to get high, so it's barely worth considering them intoxicated.

    Sure, like alcoholics aren't? Good example there, alcohol = legal drug, and a large portion of the population is directly harmed by it. Be it through drunk drivers, domestic abuse, or just the general unpleasantness that exists in being around them

    So your solution is to prohibit alcohol? Look how well that worked... Besides, the comparison between alcohol and heroin is very tenuous. The violence caused by alcohol is pharmacological, the violence caused by heroin is sociological.

    Ignoring a fact that they are incapible of actually living a normal life.

    That's just ignorant prejudice. Heroin maintenance works.

    If you hate heroin addicts so much, why not advocate legalization so it will be easier for the bastards to get what's coming to them?

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