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Coffee Maybe Not a Health Drink!

perbert writes "Canadian researchers have published a study in the Journal of the American Medical Association indicating that excess coffee drinking (4+ cups a day) could lead to an increased risk of heart disease if you have the wrong gene. In light of other studies linking antioxidants in coffee to a reduction in heart disease, who is right? Or will they cancel out in a coffee death-match?"

76 of 381 comments (clear)

  1. Dose by ThenAgain · · Score: 5, Insightful

    As with anything related to toxicology, the dose is the poison.

    1. Re:Dose by AKAImBatman · · Score: 4, Insightful

      In other words, keep it to a cup or two a day and you'll be fine. You may even reap the benefits of Coffee's antioxidants.

      If anyone ever tells you to do a lot of anything, run the other way. People have died from everything from eating too much salt to drinking too much carrot juice. Keep your diet balanced and your intakes in moderation, and you'll do far better than chasing around massive doses of things that are "good" for you.

    2. Re:Dose by ergo98 · · Score: 5, Interesting

      As with anything related to toxicology, the dose is the poison.

      To a point, however that simplifies and misses the point of the article: The researchers are claiming that there are two common variants of the gene responsible for the systems that breaks down coffee, and those with one variant are made healthier by 3 cups of coffee a day, while those with the other variant (CYP1A2*1F) are detrimentally affected by the same.

      So it's the dose...and the genes that build the systems that deal with the dose.

    3. Re:Dose by Alex+P+Keaton+in+da · · Score: 5, Interesting

      Also, as with anything else, direct causation is almost impossible to prove. 4+ cups of coffee leads to heart disease? I would postulate, not from scientific study but from anecdotal evidence gathered over years of stressful jobs, that the people under the most pressure and stress tend to drink the most coffee. So maybe the stress is what is causing the heart disease?
      Also, coffee is so acidic that people who work out everyday are not likely to be able to drink 4+ cups a day (again, non scientific anecdotal evidence). Coffee is currently fashionable, but when I think of a stereotypical coffee addict like myslelf, I dont think of a slim trim health nut...

      --
      And All I Ask is a Tall Ship And a Star to Steer Her By
    4. Re:Dose by gunnk · · Score: 4, Informative

      ... and even drinking to much water. That's actually been a problem for several years now at marathons, half-marathons and other road races. People tend to drink at every water station. That lowers their electrolytes to the point they require medical help. It's actually much more common now than people dehydrating during races.

      --
      Life is short: void the warranty.
    5. Re:Dose by ergo98 · · Score: 3, Interesting

      Coffee is currently fashionable, but when I think of a stereotypical coffee addict like myslelf, I dont think of a slim trim health nut...

      To really appreciate coffee saturation, get to know Canadian culture (particular Vancouver or Southern Ontario). We quaff coffee close to universally, from stressful to calm, and from unhealthy to healthy. Small towns feature half a dozen drive through coffee shops, all hosting endless lineups.

    6. Re:Dose by AKAImBatman · · Score: 3, Insightful
      I understand that. However, since it is impossible to know your gene type without doing a genetic workup (when was the last time the average person did that?), it makes more sense to just keep the amount of coffee down without necessarily eliminating it.

      According to the article, a cup a day is not a major risk. Two to three cups regularly, however, is. From the article:
      Slow metabolizers who drank two to three 250-millilitre cups of coffee each day were 36% more likely to have suffered a heart attack than single-cup drinkers.

      So if you're a Venti (20 oz/2.5 cups) Starbucks drinker, maybe you should consider cutting back to a tall (12 oz/1.5 cups). And avoid regularly making multiple trips to Starbucks. Once your doctor is able to start testing for this gene, then he can provide more precise recommendations for your genetic type.
    7. Re:Dose by 0NoQuarter14 · · Score: 4, Funny

      If anyone ever tells you to do a lot of anything, run the other way.

      But don't run too far.

  2. Still waking up by PornMaster · · Score: 2, Funny

    I think I should wait until the quad venti skim latte kicks in before contemplating the coffee deathmatch.

    1. Re:Still waking up by masterzora · · Score: 3, Funny

      I'm sorry, I don't speak Starbucks.

      --
      Remember, open source is free as in speech, not free as in bear.
    2. Re:Still waking up by CableModemSniper · · Score: 2, Insightful

      You know, hot liquids and milk, the curdling thing.

      --
      Why not fork?
  3. Paracelso once said... by Zaatxe · · Score: 4, Insightful

    "the difference between medication and poison is the dose"

    --
    So say we all
    1. Re:Paracelso once said... by thannine · · Score: 3, Funny

      Especially in the U.S.

  4. Who Cares by soapee01 · · Score: 2, Interesting

    Does anyone really drink coffee because supposed health benefits?

    I thought it was just the magic breakfast juice that helps me move, think, ...

    1. Re:Who Cares by TripMaster+Monkey · · Score: 5, Funny

      It is by coffee alone I set my mind in motion.
      It is by the juice of the java bean that thoughts acquire speed.
      The teeth acquire stains; the stains become a warning.
      It is by coffee alone I set my mind in motion.
      Apologies to Frank Herbert.
      --
      ____

      ~ |rip/\/\aster /\/\onkey

    2. Re:Who Cares by Scarblac · · Score: 4, Funny

      I must drink coffee. It is the mind filler. It is the little shot that brings total caffeination. I will taste my coffee. I will allow it to pass through me. And when it has gone past I will turn the inner eye to see its path. Where the coffee has gone there will be nothing. Only I will remain. Then I must drink more coffee. It is the mind filler...

      --
      I believe posters are recognized by their sig. So I made one.
  5. here we go again by dkode · · Score: 5, Interesting

    More and more often I keep hearing about things like this.

    "Doctors say more than 4 cups is bad for you!"

    then, 2 months later... "Doctors say more than 4 cups is good for you!"

    One month you hear too much fiber is bad for you, then cholesterol is good for you.

    I think as long as everyone comsumes food/drinks moderately and not go over board most people have nothing to worry about. Although, with obesity in the United States the way it is today, I would say it's already too late.

    --

    Those who trade in their freedom for security, deserve neither.
    1. Re:here we go again by hey! · · Score: 3, Insightful

      Well, I think what is missing is a technology of personal genomics.

      Salt is bad for you. Except if you don't have the gene that links salt to hypertension. In which case it isn't bad for you. If you do have that gene, then salt is very bad for you. In aggregate, given ignorance of your genes, it poses a risk.

      Experiments to date have been crude, in that they don't effectively control for genetic variation. Thus a slight bias in the genetic make-up can easily push an experiment to one or the other side of statistical significance.

      If we ever do get an efficient, fast and affordable way to do a comprehensive genetic screening, it will be of tremendous benefit to humanity. That is, after the fighting and chaos dies down, as insurance companies manage their risk to the point they become irrelevant, and families come to grips with uncomfortable holes in their pedigrees.

      --
      Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
  6. Well, by deletedaccount · · Score: 5, Funny

    I've started injecting it, so I'm not sure how this applies to me.

    1. Re:Well, by gEvil+(beta) · · Score: 2, Funny

      Sure as hell beats the coffee enema I give myself every morning...

      --
      This guy's the limit!
  7. To quote a much more sensible man than me ... by SpooForBrains · · Score: 4, Funny

    ... namely one Commander Samuel Vimes: "Coffee is merely a way of stealing time that by rights should belong to your slightly older self".

    --
    "The dew has clearly fallen with a particularly sickening thud this morning"
  8. Everything in Moderation by Makarakalax · · Score: 2, Interesting

    It shouldn't be too surprising that too much of anything is bad for you. Most food stuffs have complicated chemicals in, and thus too much of any of them can give your body a hard time due to damaging reactions, or difficulty in disposal.

    However having said this, I until recently was having something like 6 cups of coffee a day. A few months ago my body started reacting really badly to even the smell of coffee, drinking a cup gives me a terrible reaction with shivering, accelerated heart rate and light-headedness for up to a few hours.

    The stuff is nasty.

    Currently I'm drinking 6 cups of tea a day instead ;)

    1. Re:Everything in Moderation by Anonymous Coward · · Score: 4, Informative

      Your symptoms (rapid pulse, dizziness) could be an adrenergic response to hypoglycemia.

      When this happens, do you experience difficulty concentrating? (Neuroglycopenia) And does it subsequently go away when you ingest food, especially sugar? Do you experience frequent urination during the recovery phase? If it's Hypoglycemia, it is actually very dangerous for your brain.

      Caffeine's kick comes from its ability to expedite the transport of sugar from the blood to the tissues. The occasionally dangerous side effect is that if you have a problem with your diet and/or anrednal glands, since caffeine creates this metabolic illusion of an energy boost, the combination can sometimes result in depleting the blood of sugar faster than this sugar can be replenished. Then you crash dangerously hard, experiencing what insulin-dependent diabetics refer to as a "hypo."

      When your brain detects low blood sugar, it triggers the release of adrenalin and cortisol which are stress hormones, and this causes your body to release emergency sugar from other sources, such as stored glucagon from your liver.

      So most of the unpleasant effects of hypoglycemia are actually your body's defense against it. But you are 100% right to avoid coffee if it does that to you, since this is a warning sign. Coffee does not do this to everybody.

      Whatever the problem is, things can likely be brought back into balance just by eating moderate balanced meals, and having healthy snacks between meals and before bed. If you eat a lot of sugar, take it with some protein and/or fat so that your pancreas never gets habitually braced for dealing with big jolts of sugar... because it'll get itself into a mode where it produces too much insulin at the wrong time... which can be as dangerous as the legendary diabetic insulin overdose. So ironically, too much sugar can cause hypoglycemia.

      Definitely talk to a Dietician.

      Possibly at some point in the future, you might consult an Endocrinologist if you've been bingeing on high-sugar foods, and you think you might be at risk of developing type II diabetes or something like hyperinsulinism or hypoglycemia. (The latter two may actually be somewhat common. It's the diagnosis for them which is exceedingly rare, since they are both very difficult to get clinically diagnosed. Pretty much only the textbook cases that present under ideal circumstances will ever get diagnosed.) You almost have to be pretty sick before an Endocrinologist will be able to help you.

      Good luck...

      PS:
      I personally had just one episode of "reactive hypoglycemia" involving just one strong coffee, a skipped breakfast and some physical exertion, and it felt exactly like the experiences you describe having with coffee. I did not lose consciousness, but the experience did leave me with some very subtle brain damage... (which I seem to be adapting to finally after 6 weeks.)

    2. Re:Everything in Moderation by graikor · · Score: 2, Informative

      I'm more than a little concerned, not because coffee makes me jittery (it does), but because I seem to keep caffeine in my system for a long time. If I drink a caffeinated beverage after noon, there's a good chance I may still have enough caffeine in my system to keep me awake after 2:00 a.m.

      I've known for some time that I process caffeine more slowly than many of my friends, but with the results of this new study (and a family history of heart disease), I believe I will have to seriously reduce my coffee intake.

      Bummer...

  9. The coffee dilemma; a management perspective by dcavanaugh · · Score: 4, Funny

    Health hazard or health drink? What to do? The answer is simple. Find studies that support your pre-determined point of view and use those to guide the decision. I like coffee very much. Caffeine addiction is not a problem so long as I can find at least one study that proves how healthy my coffee habit is.

    Now back to our regularly scheduled programming, "TCO analysis for the enterprise"

    1. Re:The coffee dilemma; a management perspective by wrfelts · · Score: 3, Funny
      The corporate TCO Analysis goes something like this.

      The peons like coffee. We need more productivity. Coffee is a stimulant. Give them more coffee to increase productivity. Oops, now they spend too much time around the coffee pot! Buy bad coffee, they are addicted anyway. Oh no, now their health is declining and our insurance bills are going up! No problem, just make them pay most of the premiums. They won't be able to afford to quit that way...

  10. Ex Caffeine Junky by garcia · · Score: 5, Interesting

    I was basically forced to quit drinking caffeine in Decemeber. This was not something I ever expected to be able to do. The migraine lasted for about a week straight but I have been basically fine since.

    Since I was 22 I have had high blood pressure. I've spoken here about it before and complained about the high cost of Rx meds to control it and my belief that my Doctor (undercompensated by my insurance provider) is possibly pushing name-brand drugs instead of their generic counterparts to recoup some of that cost in kick-backs.

    Anyway, I was gaining on 200mg daily of various meds to control the BP. I was also gaining in daily consumption of caffeine. After switching to Diet Cherry Vanilla Dr. Pepper (aka Liquid Crack) I was heading for 5 to 6 20oz bottles a day (at work) plus 5 to 10 12oz cans every two days (at home).

    After quitting the caffeine habbit I'm on 10mg of BP meds (about $10 a month) and water.

    So, if you're looking to limit your heart disease and the high cost of protecting yourself against it with prescriptions, you might want to first take a look at your caffeine intake. It worked for me.

    1. Re:Ex Caffeine Junky by Epi-man · · Score: 2, Insightful

      After switching to Diet Cherry Vanilla Dr. Pepper (aka Liquid Crack) I was heading for 5 to 6 20oz bottles a day (at work) plus 5 to 10 12oz cans every two days (at home).

      Let's see here, 100 ounces at work, plus another 48 ounces at home, on average, every day. That's over 1 gallon of soda a day! How often did you have to go to the bathroom? They are working hard to get people to drink just over half a gallon of water a day, and here you are more than doubling that in soda, I take it moderation isn't (wasn't) your strong suit? Imagine if that had been the fully leaded version, you would have had over 1800 calories a day in colas alone (Dr. Pepper (my liquid crack) is 150 cal/12 ounce can, I'm fairly sure the Cherry Vanilla has even more, but can't swear to it)! That's most adults' daily allowance (at least, that's what my wife (MD) keeps telling me).

      I can relate to the compulsion to always have a drink on hand, after kidney stones at a young age, my doctor told me I basically was constantly dehydrated -> stones. Now I have my water cup at work, and drink over a gallon at work a day. Happily, it has been 4 years since my last stone, my fingers are crossed there won't be another!

    2. Re:Ex Caffeine Junky by Antimatter3009 · · Score: 2, Interesting

      I'm with you on this one. I used to have trouble sleeping and just generally felt bad a lot of the time. I would drink at least one large cup of coffee and upwards of 4 cans of soda a day (I know, a tiny amount by comparison to some people, but it was enough for me). I managed to stop my caffeine (and most of my sugar) intake for about 3 months almost completely. After that I felt much, much better. That was about a year and a half ago. Now I drink one large cup of coffee and maybe one (diet) soda a day. Sometimes I feel like that is still too much, but overall I feel a lot better. I would recommend this type of thing to anyone who feels like crap due to the caffeine and sugar. If you can just scale it back and maybe switch to a diet soda it will help a lot. There's also exercise, but I'm not going to get into that on /. :)

    3. Re:Ex Caffeine Junky by Anonymous Coward · · Score: 2, Funny

      Quitters...

  11. In other news... by BecomingLumberg · · Score: 4, Funny
    In other news, drinking/eating too much of $SUBSTANCE could lead to $HEALTH.PROBLEM.

    --
    If a nation expects to be ignorant and free, in a state of civilization, it expects what never was and never will be.-TJ
  12. What does this mean... by dantheman82 · · Score: 5, Funny

    for the future of Java? For now, I'm drinking green tea and coding in C#.

    --
    This sig donated to Pater. Long live /.
  13. You Misunderstand by Makarakalax · · Score: 5, Insightful

    What happens is that conflicting summaries get posted around the Internet and everyone thinks scientists are just having them on.

    If you look carefully the summary for the research is saying the caffeine is bad for you, and that the study concluded this based on research into coffee consumption. The other studies that claim coffee is good for you were actually referring to other chemicals in coffee, not the caffeine, nor the entirety of the coffee.

    Also people seem to think that scientists study everything about a topic before releasing results. But that is a misunderstanding about how science works. Generally scientists focus on very small areas of large topics and then propose more sweeping conclusions. Usually the media then make even more generalised conclusions that result in complete misunderstanding in non-scientists.

    Peer review is also important, often these studies are fundamentally flawed and even though the submitted paper offers a conclusion, the scientist writing it is well aware that in science, nothing is proved by one paper. Instead wait ten years for more supporting evidence, rinse, repeat and progress.

  14. Balance by ChaoticCoyote · · Score: 2, Insightful

    Anything to excess is likely to be harmful. The key is to find balance — moderation in all things, including moderation!

  15. My research results by Hoi+Polloi · · Score: 2, Funny

    I am proposing that eating a Whoopie Pie a day is part of a healthy diet. Prove me wrong and give me a pie!

    --
    It is by the juice of the coffee bean that thoughts acquire speed, the teeth acquire stains. The stains become a warning
  16. Personal record is four 10 cups pots by The+Ape+With+No+Name · · Score: 2, Funny

    In a 24 hour period. If you are not hallucinating by 11AM, it's time for another cup of coffee.

    --
    Comparing it to Windows will be a moot point, since El Dorado is going to have a 40% larger code base than XP.
  17. Studies have shown... by Anonymous Coward · · Score: 5, Funny

    "Studies have shown that research causes cancer in lab rats."

  18. An example of interpolating narrow research by swalker42 · · Score: 2, Interesting

    I think the problem with stories like this is that broad generalizations on health are made using one narrow area of research. In this case it is discovered that 4+ cups a day may cause heart disease.
    Wait! Only if you have a certain gene that expresses itself. Or maybe it's because the gene causes a stressful life and it has nothing to do with coffee.
    Perhaps in 20 years 1 cup a day will cause colon cancer. Maybe it will help you live 20 years longer. We are far too willing to jump to holistic health decisions based on a single narrow study.
    I would hope that no one would make drastic life decisions (not that drinking/not drinking coffee should be that drastic) based on a single study.
    Cut back on fast food, drink more water, eat more fruits and vegetables. My mom was trying to tell me that 20 years ago. You feel better and your body can better handle the impurities that you put in it. Then you don't have to focus so much on the small stuff.

    --
    You keep using that word, I do not think it means what you think it means
  19. Totally offtopic about your signature by fistfullast33l · · Score: 5, Funny
    while ($beer != full) { $beer = new Beer(); chug($beer); }

    So here's a small problem with your signature - you run the while loop until the beer is full...but you chug the beer inside the while loop. Which means that once your beer is full...you stop drinking. Of course, this is all dependent upon the fact that chug doesn't empty the glass, which is usually what happens when you chug...so basically I think you need to check the return of chug to make sure it didn't fail. Otherwise you might have problems.

    Sorry for wasting your time.

    1. Re:Totally offtopic about your signature by LunaticTippy · · Score: 2, Informative

      If chug fails you don't need another beer.

      --
      Man, you really need that seminar!
    2. Re:Totally offtopic about your signature by Placido · · Score: 2, Funny

      I think his loop is never entered if the first glass is full... OR... he ends up with a hell of a lot of half-empty beer glasses. Personally, I was thinking more along the lines of:

      $beer = new Beer();
      while ($beer != empty) {
        chug($beer);
      }

      But actually what you want is:

      while ($wallet != empty){
        $beer = new Beer(getDollar($wallet));
        while ($beer != empty) {
          chug($beer);
        }
      }

      With an optional:

      if ($upright == true){
        attemptToPull();
      }

      I guess the moral of the story is to triple check your code before posting on /.

      In re-reading this I'm coming to terms with the fact that maybe I need to GET A LIFE!

      --

      Pinky: "What are we going to do tomorrow night Brain?"
      Brain: "I would tell you Pinky but this 120 char limi
    3. Re:Totally offtopic about your signature by flooey · · Score: 4, Funny

      In re-reading this I'm coming to terms with the fact that maybe I need to GET A LIFE!

      Or a beer.

    4. Re:Totally offtopic about your signature by Edd · · Score: 2, Funny
      This is where Perl's syntax can make the meaning of a statement clearer, consider how much easier it is to understand the semantics of:

      drink(new Beer()) until $unconcious;

  20. Fittingly Canadian Story by slashbob22 · · Score: 4, Interesting

    I can only laugh as I sip on my Large Double-Double[1] Coffee from Tim Hortons. Coffee can kill me, my Work may kill me, walking across the street is dangerous. On the plus side, the coffee helps me cope at work and keeps me alert as I walk across the street: reducing 2 out of 3 risks isn't too bad.

    [1] For those not in the know: double-double -- a coffee with double cream, double sugar (especially, but not exclusively, from Tim Hortons). http://en.wikipedia.org/wiki/Canadian_slang

    --
    Proof by very large bribes. QED.
    1. Re:Fittingly Canadian Story by whitehatlurker · · Score: 2, Insightful

      The only danger to a double-double is falling asleep in the line-ups at Timmy's, waiting to get served. None the less, I will be having my ExLarge, two cream shortly. (Hopefully before the shakes kick in.)

      --
      .. paranoid crackpot leftover from the days of Amiga.
  21. Re:The baffled geek cries out by qw(name) · · Score: 3, Interesting

    I see your joke but it really is pathetic how one study tells you this and another tells you something contrary. I remember when eggs were good for you and then they weren't and now they are good again. Apples were good for you ("An apple a day keeps the doctor away") and then they weren't ("The sugar in an apple can rot your teeth", my dentist told me.). Now, they are good for you again. And there are other examples out there.

    And the other thing that should not amaze me as much as it does is grammar. How about "Coffee May Not Be a Health Drink". "Coffee Maybe Not a Health Drink!" sounds like Ebonics.

  22. 100 cups by DaFallus · · Score: 2, Funny

    Bender: "You seem a tad wound up, buddy. And your face is greasy. Real greasy. You've been up all night?"

    Fry: "Of course I've been up all night! Not because of caffeine, it was insomnia. I couldn't stop thinking about coffee. I need a nap." *snores* "Coffee time!"

    --
    No one cares what your captcha was

    Houston TX, USA
  23. Aspartame by AnonymousPrick · · Score: 2, Insightful
    After switching to Diet Cherry Vanilla Dr. Pepper (aka Liquid Crack) I was heading for 5 to 6 20oz bottles a day (at work) plus 5 to 10 12oz cans every two days (at home).

    Too much Aspartame gives me wicked headaches. Aspartame also breaks down into formaldehyde by your liver - how much or how long - I don't know, but that's what I've been told by a dietician - a real dietician from a hostpital. Not your typical "self educated" one who learned about diet from magazines thay, well, may not be the best source for that kind of information.

    --
    Saturday is April 1. Slashdot will be shut down. Sorry for the inconvenience.
    1. Re:Aspartame by Anonymous Coward · · Score: 4, Informative

      Your dietician needs to go back to med school. Yes, aspartame breaks down to formadehyde as the tail end of the process of your small intestine converting it to methanol. Formaldehyde (from methanol) is a normal chemical to be found in your body as a normal byproduct of normal digestion.

      The amount of methanol produced by Aspartame in the body is 10% of the ingested aspartame. Assuming all the methonal is further converted to formadehyde, a normal 12 oz soft drink causes only 1/6th the amount of methonal production as an equivalent drink of Tomato Juice (which contains no Aspartame, but contains other "natural" chemicals that produce methanol).

      The actual numbers are this:

      A 12 oz diet soda contains 225 mg of Aspartame (approximately 0.05% of the drink is aspartame). That generates 22.5 mg of methanol, or about 0.005% of the drink will become methanol. We will assume all the methanol becomes formaldehyde (worst case). The LD50 of formaldehyde is 100mg/kg. For an average male of 75 kg, that would mean 7500mg. A total of 333 sodas must be drank by this average male to assure death, and they must be drank fast enough to counteract the body's natural ability to rid itself of formaldehyde.

      Of course, hyponatremia will set in, without exercise or dry heat, with drinking about 3 or more litres of fluid per hour, for serveral hours straight. 333 sodas will contain 3996 oz of liquid, or about 118 litres. Anyone attempting death through ingestion of Aspartame by soda comsumption will surely die of hyponatremia far before they have reached even small amount of their goal!

      Feel free to ask your dietician to verify this!

  24. What size cup we talkin' bout here? by mottrytell · · Score: 2, Funny

    Is that 5oz, 8oz, 16oz, or the venti? I drink a lot....am I gonna die now?

  25. hype by noopy · · Score: 2, Funny

    The hype-meter on my toolbar is pegged to the right. One questionaire, not even a clinical trial, about a substance with many, many compounds and they've got the results pegged to one allele that metabolises just one compound, caffiene, slowly. Let's put a "why do you loose sleep" on the slashdot poll. May as well conclude that slashdotters who loose sleep staying up all night do so because of cowboy neal. Well, so long as they have some odd genotype.

  26. please read more carefully in the future by raygundan · · Score: 5, Insightful

    Blame the media's lousy science reporting or poor reading comprehension skills, but what people see as conflicting results are often nothing of the kind, they just miss the details.

    I saw one study that said a single cup of coffee a day was good for athletic training, and another that said that the more coffee you drink, the lower the risk of heart disease.

    This study says that more than four cups of coffee a day are bad for you if you have a particular gene.

    None of these things are contradictory-- just like how a glass of wine may be beneficial, but 10 glasses may cause liver disease. Or how some types of cholesterol are good, but others are bad.

  27. Two Apropos Quotes by SeanDuggan · · Score: 3, Funny
    "You know you're old when you remember when bacon, eggs, and sunshine were good for you."
    "Studies show that research causes cancer in lab rats."

    Quite honestly, all that these studies keep showing is that we still really don't understand how it all works and that, for now, you should just go ahead and eat what makes you feel healthy and good.

    --
    This sig has absolutely no significance and serves only to take up screen space and waste the time of the reader.
  28. Coffee by Himring · · Score: 4, Funny

    I quit all other drugs in my life. The only thing I have left is coffee. They can take it when they pry it from my cold (well, warmed), dead fingers. I started drinking it in college and fell in love. It's the right way to start a morning. It doesn't offend with its smell like tobacco. It doesn't impair driving like alcohol. It is the primordial source of gathering in the break room. It is the basis for the original Terry Tate, Office Linebacker skit. It gives cops something to hold along with a donut. It provided cease fires during the Civil War as the south traded tobacco for coffee with the north. It is the foundation of eclectic, bohemian establishments wherein college kids make it, and other college kids drink it (coffee shops) and also birthed some of the first public access to the Internet outside of libraries. It is a primary staple product in many South American countries. It's something that (according to my systematics professor) the English don't make very well. It revs you up before anything you need revving up for. I use it before my workout too. It is best when freshly ground and french-pressed. It has created many wonderful cups that say things on them. It gives dentists something to clean during checkups. Wtf beat it up? Study says this/study says that.

    Next: water -- a study shows too much of it can make your lungs stop producing needful oxygen....

    --
    "All great things are simple & expressed in a single word: freedom, justice, honor, duty, mercy, hope." --Churchill
  29. Time for a bigger cup by Helmholtz · · Score: 4, Funny

    Since it's the number of cups that makes a difference, I guess I just need to switch to a bigger cup .....

    --
    RFC2119
  30. The Gene is the Poison by drooling-dog · · Score: 3, Informative
    As with anything related to toxicology, the dose is the poison.

    In this case, it may be the gene that's the poison. It appears that a gene called CYP1A2 determines how fast you metabolize caffeine, depending on which of two variants you have. People with two copies of the variant CYP1A2*1A metabolize caffeine about 4X faster than those with two copies of the other variant, CYP1A2*1F. The study found that more than 2 or 3 cups of coffee a day increases the risk of cardiovascular disease for the slow metabolizers, but may actually reduce it for those carrying CYP1A2*1A.

    That could be why studies on the health effects of coffee have been all over the map. The trick is to know your genotype with regard to CYP1A2, and of course very few of us do (or can)...

    See http://www.newscientist.com/channel/health/dn8816. html

  31. Re:The baffled geek cries out by American+AC+in+Paris · · Score: 2, Insightful
    I see your joke but it really is pathetic how one study tells you this and another tells you something contrary. I remember when eggs were good for you and then they weren't and now they are good again. Apples were good for you ("An apple a day keeps the doctor away") and then they weren't ("The sugar in an apple can rot your teeth", my dentist told me.). Now, they are good for you again. And there are other examples out there.

    ...well, would you rather that scientists just sat on what they have until they're absolutely, positively sure they're right? That way we'd never need to deal with contradictory discoveries. We wouldn't know where babies come from, but at least we wouldn't need to deal with the embarassment of learning that mammalian ovaries don't work the way we always thought they did.

    Stuff is complicated. Be glad that we strive to make progress, even when it means saying, "whoops, we were wrong."

    --

    Obliteracy: Words with explosions

  32. best not to have any coffee by Anonymous Coward · · Score: 3, Insightful

    As with all addictive substances, it's best not to become addicted.

    Two cups a day means you are addicted. If you "need" a cup a day, you are addicted.

    1. Re:best not to have any coffee by KDan · · Score: 2, Interesting

      Tip for breaking the vicious cycle: I've stopped drinking coffee twice... once cold turkey, once progressively after getting back into it through the devious paths of coca-cola and green tea (I didn't realise green tea had caffeine).

      I found that breaking off progressively was *much* easier than all-of-a-sudden. You don't get all the psychological trip where your brain tries to convince you that you *must* have a cup otherwise something bad will happen (eg. you won't be sharp enough to do your job, etc). Breaking off cold turkey was a nightmare for a whole week, then progressively got better. Breaking off progressively (cutting my consumption by half every week, until I was having half a cup of espresso every other day, and then nothing at all) worked a LOT better, very smoothly. I don't even recall having any coffee cravings when I did that.

      Daniel

      --
      Carpe Diem
    2. Re:best not to have any coffee by flyingsquid · · Score: 4, Interesting
      As with all addictive substances, it's best not to become addicted. Two cups a day means you are addicted. If you "need" a cup a day, you are addicted.

      It's not like it's freakin' heroin or something. First of all, you're probably better off being a "hard-core" coffee addict than a casual user of cocaine or heroin. Second, last time I checked there weren't any twelve-step programs for coffee drinkers, or patches to help them quit. That suggests that either people don't have a problem with being regular coffee drinkers, and/or they don't have much of a problem quitting if it's making them irritable, sleepless or whatever.

      The whole "addiction" thing is just a little out of hand. When I'm working out in the desert I may drink two liters of water a day, and damn sure I feel a "need" for water when its 90 degrees. So I'm a water addict? To be an addiction, I think it has to (a) be seriously detrimental to your well-being, and (b) you have to have serious trouble quitting. Coffee doesn't meet either of those criteria.

    3. Re:best not to have any coffee by Hatta · · Score: 3, Interesting

      It's not like it's freakin' heroin or something. First of all, you're probably better off being a "hard-core" coffee addict than a casual user of cocaine or heroin.

      Actually, if you're sure of the purity and dose of your heroin it's very physiologically benign. It's just an opiates, and pain patients use opiates their entire lives. If heroin were legal it would be cheap enough that addicts wouldn't have to steal to get it, and wouldn't be stigmatized by being an addict. Because of tolerance the actual deleterious effects of being opiated go away. They could live entirely normal lives.

      --
      Give me Classic Slashdot or give me death!
    4. Re:best not to have any coffee by Hatta · · Score: 4, Insightful

      Open your mind, most junkies are just normal people who made some bad choices. Given that we can't stop them from using, we may as well try to minimize the damage those choices inflict.

      Opiates to build tolerance on their own, so said legal junky will still need more and more.

      People on heroin maintenance programs tend to acclimate to a dosing schedule that keeps them functional. They're so tolerant that they literally can't get enough to get high, so it's barely worth considering them intoxicated.

      Sure, like alcoholics aren't? Good example there, alcohol = legal drug, and a large portion of the population is directly harmed by it. Be it through drunk drivers, domestic abuse, or just the general unpleasantness that exists in being around them

      So your solution is to prohibit alcohol? Look how well that worked... Besides, the comparison between alcohol and heroin is very tenuous. The violence caused by alcohol is pharmacological, the violence caused by heroin is sociological.

      Ignoring a fact that they are incapible of actually living a normal life.

      That's just ignorant prejudice. Heroin maintenance works.

      If you hate heroin addicts so much, why not advocate legalization so it will be easier for the bastards to get what's coming to them?

      --
      Give me Classic Slashdot or give me death!
    5. Re:best not to have any coffee by kaniaro · · Score: 2, Funny
      Maybe not an addiction, but definately bad for sotware development. According to the APA:
      "Bill Gates has been quoted saying that his programmers can program for 72 hours straight," Stickgold says. "And I say-yeah, but their product is Windows."
    6. Re:best not to have any coffee by raoul666 · · Score: 2, Interesting

      So your solution is to prohibit alcohol? Look how well that worked... Besides, the comparison between alcohol and heroin is very tenuous. The violence caused by alcohol is pharmacological, the violence caused by heroin is sociological.

      Overall I agree with you, but I just thougth I'd mention that some studies suggest that the link between alcohol and aggression is sociological as well - in a study I read, people who believed they consumed alcohol, whether they had or not, were more aggressive than people who didn't think they had consumed alcohol, whether they had or not.

      --
      When cryptography is outlawed, bayl bhgynjf jvyy unir cevinpl
  33. Not just dose. by slughead · · Score: 2, Insightful

    As with anything related to toxicology, the dose is the poison.

    Not to mention the person's physiology. There's a reason they call the lethal dose of something the "LD50", and that's because that's the dose at which 50% of the animals they injected the substance into died. (they measure it in milligrams of drug per kiligram of animal, in case you're wondering).

    Some people are immune to AIDS, some people are allergic to peanut butter, in some people Ibuprophen works for headaches, in others Asprin or Tylenol works. Sometimes people are just plain different.

    There was an article in The Economist (print edition, so I wont bother linking) about how doing DNA tests on people and finding out how they would react to drugs would save a lot of time and possibly lives. The reason we don't is because it's expensive and people (all of a sudden, and seemingly on this issue alone) are concerned about privacy.

    There was a reason 1 out of every 100,000 people who took Vioxx died, and it's not because Merck was "evil," it's because they simply couldn't account for all the different physiologies out there. Don't worry though, the law suits will certainly ensure higher prescription drug prices in the future, all due to ignorance and jerks like James Sokolove. :)

  34. HA! Take that, you caffeine-addicted wankers! by wheany · · Score: 3, Funny

    I really don't get geeks' caffeine worship. Some seem to think that it's somehow a good thing to not be able to wake up properly before drinking half a pot of coffee.

    Oh, and all you self-righteous green tea drinking hippies are no better.

    1. Re:HA! Take that, you caffeine-addicted wankers! by Creepy · · Score: 2, Funny

      I can think of a several good reasons to worship caffeine

      1) it doesn't impair your ability to work, which isn't true for most other substances
      2) it's often free at workplaces and available at schools (usually in soda form for the latter)
      3) it's better than being SMITTEN by the CAFFEINE GOD, you self-righteous caffeine-free prick.

      ok, 3 was really to poke fun at you ;)

  35. This study once said.... (and it disagrees) by raygundan · · Score: 2, Informative

    It's not the dose that matters here, it's whether or not you have a particular gene that slows the metabolism of caffeine.

    For folks with the gene, even two cups was harmful. For those without, the more the merrier. Please read more carefully.

  36. Caffeine as a meditation aid by kwahoo · · Score: 2, Interesting

    I like to have a dose of espresso before meditating. It makes it more challenging. /K

  37. Warning: This May Be Harmful To Your Health by ackthpt · · Score: 5, Funny
    "Coffee Maybe Not a Health Drink!" Gasp! :-)

    From a life-long geek's perspective:

    • I've sat for hours, for years in front of 25" colour TVs before they reduced radiation emissions.
    • I've eaten countless bags of crisps flavoured with chemicals for visual and taste enhancements and dusted with MSG
    • I've eaten countless pounds of fried foods
    • I've made my share of /. typos (inadvertent and purposful)
    • I've raced on a bicycle over 60 MPH downhill
    • I've been hit with kilovolt shocks
    • I attended dozens of indoors Hamfests, choked with the smog of hundreds of cigarettes, plus a few pipes and cigars.
    • I've been run over by a car
    • I've drunk a Mickey's Bigmouth
    • I flew on a jet that bounced on the runway at Baltimore
    • I fell out of a raft in the middle of Lost Paddle class V rapids in the Upper Gauley river of West Virginia
    • I've collided with my brother's sled on an icy hill in Michigan, nearly fracturing my skull.
    • I've been in 3 auto accidents
    • I've lept off a 40 foot cliff into a flooded quarry
      • I'm not done yet.

        Regarding health, it will be bad for someone's if I don't get my coffee.

    --

    A feeling of having made the same mistake before: Deja Foobar
  38. key piece of the puzzle is missing... filtered? by Creepy · · Score: 2, Interesting

    I don't mean to discount their identification of a genetic link (which I think is valid), and I have no idea how Costa Ricans drink their coffee, but previous research has identified a risk in unfiltered coffee like that through a percolator or French press (or Turkish, Espresso machine, etc) vs filtered coffee. Since terpenes (oils) in unfiltered coffee are suspected raising cholesterol, it is possible that elevated cholesterol levels from drinking unfiltered coffee may also play a role here.

        In any case, having that gene and drinking a lot of unfiltered coffee would put a person most at risk, I would think.

  39. Who funded the study? by deviantphil · · Score: 5, Insightful

    A lot of who is right depends on who funded each study and what they set out to prove (or disprove) in their study.

  40. The STRESS of not knowing what to eat by JohnnyGTO · · Score: 2, Funny

    is going to kill us!!

    --
    Si vis pacem, para bellum! For evil to succeed good men need only do nothing!
  41. Re:No. by Hal_Porter · · Score: 2, Funny

    A US cup is 236 ml

    Or it's 48 US teaspoons

    or half a US pint, or 41.6% of a uk pint

    If the cup were full of tea made out of antimatter and it combined with a cup of normal matter it would produce a blast of about

    10.6 megatons

    So 22g of antimatter+22g of normal matter=1 megaton. This is a very useful thing to know

    --
    echo -e 'global _start\n _start:\n mov eax, 2\n int 80h\n jmp _start' > a.asm; nasm a.asm -f elf; ld a.o -o a;
  42. Q: who is right? A: it depends on you. by gordguide · · Score: 2, Informative

    Q: " ... In light of other studies linking antioxidants in coffee to a reduction in heart disease, who is right? ..."

    A: Since it's the presence of a gene that matters which is right, Check family history:
    Look for heart disease or diabetes (essentially, the same thing as far as your likelihood of heart disease goes). If found, avoid coffee.
    Check family history again, look for average age at death. If less than 60 for males, assume heart attack, avoid coffee.
    For females, ignore childbearing age, look for deaths aged 40~60. If found, assume heart disease, avoid coffee.

    If most of your ancestors and siblings seem to live past 70, assume decent heart, drink coffee.
    If most live past 80, you may safely ignore cause of death, even if from heart attack, because they didn't "really" die of a heart attack, they died because they were healthy and got old, like all healthy people do and everyone dies of something. Drink coffee.

  43. And caffeine also has good benefits by Calyth · · Score: 2, Informative

    In another study, they said that caffeine can help Ashkenazi women to reduce their risk of getting breast cancer. However, the most effective dosage exceeds 4 cups.
    Just like anything that a human can ingest, moderation is the key. Try drinking gallons of water in a short period and see whether that would kill you.