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Overly Sanitized Environments Lead to Poor Health?
bignickel writes "A recently-released study examined the health implications of living in an overly hygienic environment. According to the 'hygiene hypothesis,' living in such an environment early in life can lead to problems with allergies and autoimmune diseases. The study compared lab rodents with rats and mice living in the wild. Time to stop Lysol-bombing the house?"
It will be no problem at all if there are moon colonies. But, as we all know there aren't (although some conspiracy theorists know there are).
Acting stupid isn't much fun when there's someone around who knows better
My mother was stricken with Polio in the early 50's, just a few years before the vaccine was approved.
Although I've never seen any literature that support this, she says Polio was known as a Middle-class disease, since the middle-class were more likely to have cleaner houses (thus not exposing babies to as many germs and developing healthy immune systems). The fact that her mother was a clean-freak before and after my mother was born may be coincidental to her contracting Polio, but I like to think they're related.
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2B1ASK1
There's an easy way!
"Powers. I have them."
This is based mostly on BS, but interesting (at least to me) nonetheless...
When my mom was pregnant with me, at some point she had a bad case of poison ivy. I rarely ever get poison ivy, and if I do, it's only for a couple days, and is hardly noticable. My older sister on the other hand, is quite allergic to poison ivy, and generally needs medication to control it if she gets it. I've also heard of similar stories, but can't be arsed right now to remember them. Now, we all know that a baby's immune system is related to how good the mother's immune system is. I postulate that if a pregnant woman becomes infected with any sort of non-fatal/non-life-threating disease, bacteria, virus, the baby will, as a result, be more resistant to it, if not totally immune.
So, instead of isolating pregnant women from everything, I say we start giving them controlled infections of common sicknesses, so that their immune systems produce the atibodies, and pass them on to the baby.
Of course, I could just be completely insane....
Everything I say is a lie. Except that... and that... and that, and that, and that, and that... and that.
I often work inside a clean room, and once I saw a colleague of mine have a severe hay fever attack in there. Tears streamed from his eyes etc. He had to sit down for a while to recover. He told me it's the change of environment (in this case from dirty to clean air) that did it for him. Very strange.
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That information, while useful, would probably be less useful than you might think. Even if you discount the typical problems associated with questionnaire-based studies, such a study will won't distinguish between problems caused by sterile environments and problems caused by different allergens that may be associated with air conditioning systems or with urban areas in general.
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IIRC, the original study that popularized this idea compared Germans who grew up in cities and on farms and found a lower rate of allergies in the latter.
As for this mouse study -- lab mice and wild mice are extremely different animals, as lab mouse strains (which used to be pet mouse strains) as have been selected for two hundred years to grow in close quarters. It's very hard to distinguish environmental and genetic effects in this case.
What I'm listening to now on Pandora...
Like you said, that is your *personal* experience.
Whereas I grew up just as you did, playing outside, lots of different animals, hay, etc. Not a Lysol environment at all. And then around 10 years old, while making tunnels and forts in a big pile of haybales with friends I got hit with the hayfever. Around the same time I developed an allergy to cats. My father is exactly like this and his father is as well (allergic to cat dander and have hayfever).
Oh, and you can be born with allergies. I'm allergic to penicillin - given some as a newborn and developed a rash (apparently a common allergic reaction to it).
I'm sure that there are others that can refute your hypothesis.
But I still believe that it is good to not grow up in a sterile environment. I'm not thinking about allergies, but just about having an immune system that gets some exercise and building up a catalog of antibodies that can respond to similar threats. (in fact, isn't the allergic reaction your immune system's response to that allergen?)
As I understand it, the immune-strengthening effect doesn't come from exposure to high concentrations of pathogens, but from ongoing low-level exposure: playing in the sandpit, swimming in the river, that kind of thing.
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...I have a personal counterpoint to some of them. I grew up doing a lot of the typical outside kid things, but still ended up with some pretty bad allergies to grass and other pollens. That doesn't mean I don't agree with the article - I think it's fairly intuitive that a too-clean environment results in a weaker immune system. Just saying that the reverse isn't guaranteed.
It could also be that those with allergies tend to move away from the farms. I wouldn't last a week on a farm without some Zyrtec.
My sister and I grew up in the same environment. We lived in air conditioning, but spent most of our childhood playing outdoors in suburbs of Minneapolis. I have severe pollen-based allergies. If I do not have air conditioning or medication, I can wake up with my eyes glued shut from secretions, my throat can hurt like the worst strep throat you ever had, and my eyes and ears itch constantly. I am also mildly allergic to pretty much every food. My sister has no allergies of any kind.
My family was on the farm two generations ago, and one generation ago they still worked on the farm during the summer. Some of them have allergies, some don't.
My daughter's skin has reacted to certain foods since she was a baby.
So, I think there are probably genetic predispositions to allergies. However, I think there may be a role for environment in those who are less severely predisposed to allergies than the members of my family.
I cna't say I agree with this article. I grew up in a mid atlantic state in the 80s. Our house had no a/c, so I was exposed to dust and pollen from the outdoors year round, plus I was outside playing a lot. Mom was a pretty busy person, so things like dusting and vacuuming weren't as regular as they were in other people's houses. I've been stuffed up my whole life and this past year I was tested for allergies, it turns out I am allergic to dust, mold, and various tree pollens. Basically 3 things I have been exposed to my entire life.
Intuitive: I figure your immune system is like anything else in your body -- if it doesn't get a regular workout it becomes less efficient and when you stress it, it may behave unpredictably.
Anecdotal: I grew up playing outside a lot. My favorite thing to do was hydraulic engineering on mud-puddles. I built dams, canals, locks with gates, stirred up mud to see how it behaved, etc. I was out in the woods a fair bit, got the occasional tick (this was before Lyme disease was such a concern, and as long as you caught the ticks the same day, Rocky Mountain Spotted Fever was nothing to worry about). We had cats, our relatives had dogs, etc. To this day I have relatively little issue with allergies or illnesses of any kind. Yes, dust makes me sneeze, but it honestly puzzles me why people stampede to get flu shots every year -- I've had the flu maybe twice in my life, it sucked, it lasted about three days each time, and I got over it. People look at me like I'm nuts -- "You're not getting a flu shot? WHY NOT???"
On the other hand, just about all the people I know with allergies, constant colds, etc. are the ones with a horror of anything that might be less than perfectly fresh and germ-free. I drink milk that's a few days past the sell-by, I eat stuff that's been in the fridge a couple days, I have lunch at greasy spoons where the kitchen staff maybe doesn't wash their hands every time they touch their own face. I don't go out of my way to find "dangerous" food or items, but neither do I avoid things that may have tiny amounts of "harmful" stuff on them like my life is at risk every time I eat a sandwich.
Logical: I won't use antibacterial soaps unless there's no alternative. Why? Because using them indiscriminately breeds resistant bacteria. This is just logic backed up by known scientific observation of microbial evolution. It's the reason your doctor won't (or at least, shouldn't) prescribe you antibiotics every time you have a fever -- if it's not bacterial, the drugs wouldn't do you any good and would breed resistance in bacteria that aren't causing you any issues yet. Then those resistant strains would take over and now you have a problem, and it's a tough problem because the doctor has to give you massive doses, or use a different antibiotic -- and there are only so many antibiotics out there. Trying to sterilize the environment is the same thing on a grander scale.
If more parents let their kids go ahead and, for example, chew on the cat's tail, the kid's immune system would get exposed to a few new agents (and learn to deal with them), and the cat would swat the kid who would then learn "don't chew on kitty, it hurts". That's two problems solved. Don't let them play in raw sewage, but don't keep them in a plastic bubble either.
-- Old Man Kensey
I have a similar experience to yours. I was diagnosed as being allergic to pollen, animal dander, dust of any sort, and so on. My mom protected my brother and I from those things like crazy. When I was in the presence of a cat for example I would have a hard time breathing and my eyes would swell up and water like crazy. But guess what? After my sisters started adopting just about every stray or orphaned animal they found my reactions to them became less and less untill completely gone. At one point our house was like a petting zoo with all kinds of animals we were nursing back to health and/or rasing. The family doctor was very interested in what happened with me. At that time they were conducting a study into the theory of prolanged exposure to allergens can can help lessen or completely remove the allergic reactions. After that my parents started sending me to summer camp and again guess what? After the first 2 summers my allergic reactions to pollen were gone as well. Dust still makes me prey for death but that is the only allergy I haven't been able to shake. So yeah it's my own personal exp but I have spoken with MANY people with similar exp. Now my younger brother was not so lucky. He got the same exposure as I did but his allergies never went away. But they did decline noticably during the zoo period or our lives. But that only lasted until we left home. They have in fact gotten stronger over the years. So who knows. There needs to be more study done on this but I know in my case exposure did seem to cure me of most of my allergies.