Gates Pushes Open-Source Approach to HIV Research
dan the person writes that the Bill and Melinda Gates Foundation "has donated $287m to 16 different research groups around the world to work on developing an HIV vaccine. The catch? They have to share their work even if the groups were previously competing against each other. Sounds like a familiar development model to me, I wonder where I have seen it before?" Besides the BBC's coverage, the Seattle Times has a good story about the grant, with a few more details about how the money will be spent.
Happy that he apparently understands how progress can be achieved most efficiently, or sad that his (previous) company does anything it can to stop this kind of progress in the IT field, even though their previous boss apparently knows very well what the consequence of that is....
molmod.com - computing tips from a molecular modeling
Either way, I'm never going to be able to see the research or dump the data in to Weka and try to find correlations by mixing and matching data mining algorithms on lab data.
Also, I think it's stupid that the story implied irony that Gates doesn't use the open source model in software: I don't know where you got that quote because I can't find it in either of the linked articles. People's lives depend on a cure/vaccine/treatment for HIV/AIDS. People's lives do not depend on the development of software--especially Microsoft software, thank god. They are two very different development efforts with very different ethical connotations.
My work here is dung.
Give the guy some credit. Gotta crawl before you can run.
That which does not kill me only postpones the inevitable.
since we're talking about AIDS, shouldn't it be "Open Sores", and not "Open Source" ?
the goal of microsoft is to make money.
the goal of bill gates' charity is to help people.
why should it be surprising if gates uses different methods to accomplish different goals?
...their findings will still be restricted to the 16 groups involved
Sounds like he's trying to make the HIV research community into one big monolithic business. More like Microsoft than Open Source?
People's lives depend on a cure/vaccine/treatment for HIV/AIDS. People's lives do not depend on the development of software
Except in cases of rape, people can easily avoid getting infected with HIV/AIDS. Abstinence or safe sex cost nothing, and they have the additional benefit of reducing population growth.
You cannot avoid using Microsoft software. Every dollar that Microsoft makes in monopoly profits (i.e., every dollar that Microsoft makes that goes beyond what they would make in an efficient market) is money that's not available for public health, education, or development.
Dollar for dollar, money available for improving the economy and infrastructure of third world nations is going to save more lives than money available for an AIDS vaccine.
So, I think, overall, when Microsoft uses its monopoly profits to take money out of the economy and funnel it into the development of projects designed to make Gates look better, you're getting the worst of both worlds: money becomes unavailable for productive uses, and it is funnelled into projects that make Gates look good but are not particularly rational.
Whenever Gates pushes for open source anything, it is always wise to consider it in the light of historic precedent:
"Joshua Pushes for Jericho to have Open Wall Policy"
Greeks Push for Trojan "Open Gate" Policy.
Where were you when the voynix came?
> People's lives do not depend on the development of software--especially Microsoft software, thank god. They are two very different development efforts with very different ethical connotations.
... the dependence wouldn't be that direct, true, but people's lives depend on the productivity of society, -- if you have food, you have time to spend on developing medicine -- so I'd say there's still some dependence.
Hmmm. No, you're wrong. People's lives can depend on software. In my Data Structures class, the TA told us a horror story about a case where an operating system race condition in a chemotherapy machine resulted in people being given lethal doses of radiation.
Now as far as M$ software
The "human life" argument isn't very good anyway, rather like the classic "10,000 dead in Sri Lanka" troll. Human life is very valuable, and as a society we want everyone to have as much of it as possible, but we also want everyone to have as good a life as possible, which is why we have televisions, music, video games (software), art, literature, and tools to help us finish our work as quickly as possible, including software.
vi ~/.emacs # I'm probably going to Hell for this.
Whaddaya mean lives don't depend on Microsoft software. Shows what you know. If it weren't for Microsoft there's a lot of people who wouldn't be alive today. Hospitals depend on the reliability and robustness of Genuine Windows so that doctors can "git er done". You don't think hospitals would be stupid enough to trust vital data to Unix operating systems do you? If you think that, you're out to lunch.
oh, i see. south park can mnake a joke and its funny, but it does on /. and now all the sudden we are all serious. and besides, parent didn't make fun of the illness, he made a funny about how 'open source' is simlair to 'open sores'
From the Seattle Times Article:
I interpreted that as there is a requirement not to withold publication untill you get something really exciting. Science is fundamentally "open source". You research, you publish, then others can use what you publish in their own research. The only wrench in the works is if the researchers take out a patent. But as I read the article, there are few additional limitations on patenting:
Comparing it to Free/Open Source software is a little off, as FOSS depends on copyrights, and you can't copyright scientfic ideas and facts of nature.
I'm glad you read the article carefully enough to point out flaws in the submission. I do, however, disagree with the following:
"People's lives do not depend on the development of software--especially Microsoft software, thank god."
Ever think that mistakes in software -- even just in poorly designed interfaces -- have been directly responsible for wrong medical procedures or analyses or the like? Or that because of software flaws (some of which can be attributed to MS, but obviously not all), people's identities have been stolen? I completely beg to differ. People's lives these days depend critically upon software. And it's only going to become moreso.... (time to enforce higher-quality code.... from EVERYONE)
Once the drug is created though, gates forces everyone who was cured to buy an MS product in addition to the price of the treatment
But seriously, as long as money is going to these companies, they won't create the cure, just the temporary antidote, someone needs to be out there actually monitiring these companies (not a government orginization, they are to easily tempted by cash) just something to make sure they are developing a cure and not simply a pain reliever or placebo
Did someone say cake?
Open source actually doesn't mean much. You could do whatever and call it open source. That's the marketing beauty of the term, but it has nothing to do with it.
Open source doesn't require you to share the information you have, or the source.
Even free software doesn't. When you distribute GPLed software, you are obliged to distribute the source too, and pass certain freedoms to the guy that receives it.
But most important, it doesn't say that you have to share it at all!!!
If you have a lab, for example, and make a special linux kernel for your propriteary hardware, for internal use, you don't have to share it with anyone!.
Probably software plays a big role in the development of vaccines. Statistics can be better treated, some times, with custom software. Machine learning of course can play its role, lots of software stuff does.
Bill Gates reminds me of William Bulger: Brilliant, cunning, a great person to have on your side and a devastating enemy to have against you. Glad those guns are pointed towards HIV and TB.
Maybe it's time to separate the BG of MS and the BG of the Gates Foundation. It's seems he has.
"I hate to advocate drugs, alcohol, violence or insanity but they've always worked for me" - HST
but I do wonder how much effort is *really* being put into finding a cure/vaccine by the encumbent drugs companies.
think about it, they can either develop a cheap use once vaccine, or masses of variations on retrovirals that western govts (or individuals) will fork out for for 15+ years. Africa can't afford them and who cares? where is the malaria vaccine?
i hope this effort by billg gets some results. Mind you how much would the drug companies pay to bury that information?
im not normally this paranoid (oh i know you all think i am) but when it somes to things like this, i do wonder...
Only slashdotters bluster, compete, and condescend on pedantic points more than research scientists. Amiright?
- For every action, there is an equal and opposite criticism.
Too add on the idea that software saves lives, let's think about this in a more life threatening sense: hospitals. Recently, I had surgery. It would have been really bad if the software run IV pump gave me just a little too much morphine too quickly. It would have been bad if my state of the art EKG machine hadn't been working correctly. Hospitals run off a lot of software now.
I don't know where you got that quote because I can't find it in either of the linked articles. People's lives depend on a cure/vaccine/treatment for HIV/AIDS. People's lives do not depend on the development of software--especially Microsoft software, thank god. They are two very different development efforts with very different ethical connotations.
...Oh, and also...
I love this argument.
"Gates deserves his billions, he's had such a HUGELY IMPORTANT impact on the world! Computers have become life-saving technology, our quality of life has improved dramatically, and we've enabled positive growth across the world! Thanks to people like him, we'll become so efficient that hunger will be a thing of the past...
Its OK if Microsoft stifles competition and growth in the field of IT, because its just a bunch of stupid computers that don't really matter."
Pick a frigging side! I know you didn't say the gates-is-great stuff, so its kind of a straw man I'm building here, but for the record, heres my side: You're wrong, computers are WICKED important, and he has had a NEGATIVE impact on the field of computing by shoehorning shitty technology into places it shouldn't be [by WACK marketing practices, some of which were outright illegal, others were simply _completely_ against the spirit of the competition-fueling-growth model]. He has sold people crappy tools that made them take longer to learn stuff, thus slowing the development of lifesaving computing technology. So THERE.
Why stick up for big business?
Competitive pressure, with all kinds of things at stake such as research funding, prestige, career advancement, or even the career itself, can bring out the worst in some people. No doubt Gates has seen that. Want competition in moderation. Don't want athletes hiring hit men to break opponent's knees, or tampering with the playing field, or taking performance enhancing drugs. In this case, don't even want anyone to have an edge with legit means like superior equipment or techniques that is not available to the others. We have yet to see athletes suing one another over intellectual property issues in efforts to deny advances to their opponents. No doubt Gates has seen all that, especially among his many defeated opponents, so perhaps he can pick out groups who will keep the competition clean and minimal. No Dr. Hwangs of stem cell research infamy. And maybe Gates can write the rules and set up the game so that destructive competition is too hard or risky to be tried. That a big deal is being made of Gates' "open source" requirement suggests more people than just us Slashdot readers are aware the game of research and innovation could use a bit of cleaning up. Why, even that ultimate competitor Gates himself seems to be implicitly admitting as much. That is, assuming that aspect wasn't overly emphasized for this audience.
Intellectual Property is a monopolistic, selfish, and defective concept. It is "tyranny over the mind of man"
argue with your detractors. See what that got you? You are now flaimbait. The reason those idiots are no longer posting is because they are moderating.
Seriously, is the open source movement going to lower itself to stating that if you're aligned with Microsoft's development practices for software, then you're hindering aids research? It's a worringly bad comparison to make, and certainly one that open source as a whole should refrain from. Science has always had an air of open-ness about it, however programming operating systems is more art than science, and the reality is that whether it's a tool or a piece of art, it's going to cost you money somewhere along the line. Science conversely was an open affair, and only recently has this changed with the practices of 'Big Pharmo', who are prepared to develop a cure for aids, providing they've got exclusivity.
For once, let's just try and laud Gates for doing yet another charitable thing. He starts a foundation, and the visible heads of the Open Source hydra present themselves only to bark, despite billions going to good causes. To see it happen then was a telling sign about general maturity in the community, and to see it happen again here in the wording and tone of some of these comments is again, dispicable.
I can't imagine Microsoft or anyone who works there has ever supported the notion that work on a HIV curve should be top secret and an utter cash cow.
The real question anyone should be asking about this is whether or not requiring openness in the development of HIV cures will facilitate or hinder the process, since if there's not going to be any pot of gold at the end of it, a lot of people aren't likely to bother making the effort. At least when the patent wears off it's free, and the Chinese will liklely just make it anyway at knock-down prices regardless of IP rights. If we got the free cure in 21 years from waiting on a patent to expire, or 30 years of slower, open research, which would really be best?
If Gates and others donate enough to make it worth while, we don't have to wait 21 years. Unfortunately it's too early to tell if the money given will be enough, and we'll never know in a measurable way it's impact on private-sector development.
-Steve Gray
-Cobalt Software
>If you've got more than two brain cells to rub together, you want to opine and argue with your detractors. This is why Kuro5hin.org will always be better than Digg
:)
Fixed your post for you
or
Spend 3 billion of your own money to develop a treatment.
100 million people with AIDS (total guess) X $10 / week = $1 Billion dollars per week for the rest of their lives, and you ensure a new generation of "customers."
Yes, there are people doing research that would love to find a cure, but it takes a pharmaceutical giant to engineer, manufacture, and distribute. I wish him luck, but don't expect anyhting monumental from it.
People who think they know everything really piss off those of us that actually do.
I don't get this. The same Catholic Church that is against condoms, is also against sex outside of a monogamous marital relationship. If everyone is in strict adherence to the laws of the Church, AIDS wouldn't be the issue it is. Actually, your problem with the Catholic Church is not that they are against condom use, but that they spend their money to convert people instead of spending money to hand out free condoms... and you think somehow they should be spending their money to support things that they don't believe in? Once again, I don't get it.
"Perhaps most amazingly, votaries of 'diversity' insist on absolute conformity." -- Tony Snow
We have to ultimately decide if we want to invest our time in increasing quality of life, or in increasing quality of death. These are the main two motivational factors.
I'd prefer quality of life, I like the idea of working hard for years as life continues to get better and better. I don't like the idea of working hard as life continues to get worse and worse, more dangerous, and shorter.
How many people here actually agree on supporting quality of life?
I read both articles and I don't recall seeing anywhere that they would allow anyone access to their findings and research.
Actually this matches the GPL quite well. The GPL does not require you to make the source code publically available. It requires you to supply the source code to whoever you give/sell the program to. Thus there is no reason for the public to be able to see the code if all the parties agree to share only with themselves.
[The GPL also requires you to allow the person receiving the program to modify and redistribute it as they see fit, so they *could* make it publically available if they wanted. It is not clear if that is true here, probably not, so that is a difference]
Actually the data is amazingly transperent right now, fifteen minutes on google links after searching for "cd4 gp120" you'll find enough data about HIV infections of CD4 T killer cells to make anybodies head spin. As most research is government funded the data is pretty much available, try looking at the HIV sequence database over at Los Almos National Laboratories, all kinds of geek toys, FAQs and tutorials there. you can even run polypeptide and nuecleotide sequences against the HIV genome. The hard part about a HIV vacine is that the part of the virus the body sees is covered in sugars so the immune system doesn't respond to it!
Apocalypse Cancelled, Sorry, No Ticket Refunds
One question: where are those millions of deaths by HIV/AIDS happening? That epidemy first became widespread in the USA/Canada, but it was contained there about twenty years ago. Yet it still seems to be one of the main causes of death in Africa. So, yes, there is a close correlation between technological innovation and saving lives.
A very interesting example on how proper information management can save lives is in the book "Visual Explanations" by Edward Tufte. There he mentions how in a cholera epidemic in London in 1854 a physician, Dr. John Snow, plotted all cases in a map of London. He found the cases were concentrated around the corner of Broad St. and Cambridge St, where there was a well. Dr. Snow went there and broke the water pump, after that the epidemy subsided. That's how it was found that cholera was transmitted by contaminated water, at the time it was believed that the disease was caused by impurities in the air.
there is nothing evil about bill gates and there is nothing nice about steve jobs.