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Breakthrough In Human Genetics

Many readers have submitted this story about a breakthrough in our understanding of human DNA: in particular, how much variation can exist between peoples' genes and how genes are involved with certain diseases. "One person's DNA code can be as much as 10 percent different from another's, researchers said on Wednesday in a finding that questions the idea that everyone on Earth is 99.9 percent identical genetically. They said their new version of the human genetic map, or 'book of life,' fills in many missing pages and chapters to explain how genes are involved in common diseases. The Human Genome Project mapped the billions of letters that make up the human genetic code. Scientists later refined the map by looking for single variations called SNPs or single nucleotide polymorphisms. The CNV map gives researchers a different way to look for genes linked to diseases by identifying gains, losses, and alterations in the genome."

28 of 240 comments (clear)

  1. Spelling on Slashdot by Harmonious+Botch · · Score: 5, Funny

    One person's genetic code can be 10% different from another's, and chimps are 98% the same as humans.
    No wonder so many of you can't spell.

    1. Re:Spelling on Slashdot by bitt3n · · Score: 3, Funny

      mad parrot opp!

    2. Re:Spelling on Slashdot by DarkReign · · Score: 2, Funny

      Creationists on slashdot? I thought this place only had smart people.

    3. Re:Spelling on Slashdot by bloobloo · · Score: 2, Funny

      So you are saying that the DNA that varies in the human population is 10% of the DNA that varies in the human population?

  2. Misunderstanding by Anonymous Coward · · Score: 5, Funny

    No, no, no, no, no... this is all just a misunderstanding of scientifical facts. You see, it's only the darker folks, whom we are 10% different from, that are 2% different from monkeys. The world was made this way intentionally, presumably by some Great, Omnipotent Designer... whatever you want to call him. I know this to be true because I learned it in a museum. In Kentucky. It was right next to the exhibit with humans and dinosaurs living together.

    Honestly folks, get it together already.

    1. Re:Misunderstanding by Anonymous Coward · · Score: 1, Funny

      -1? I guess it's still too early to do Michael Richards shtick...

  3. Without stem cells?? by Anonymous Coward · · Score: 1, Funny

    All that without stem cells?!
     
    shocker.

  4. At Last by umbrellasd · · Score: 3, Funny

    My brother is explained...

  5. oblig Steven Wright by opencity · · Score: 3, Funny

    "Everyone on the earth is unique,
    except this one guy ..."

    --
    Physics is like sex: sure, it may give some practical results, but that's not why we do it.
    1. Re:oblig Steven Wright by Anonymous Coward · · Score: 1, Funny

      Who modded this Troll? WTF? If you don't like Steven Wright maybe you don't think its funny, but it sure as hell isn't a troll!

  6. more examples of fuzzy math by circletimessquare · · Score: 5, Funny

    1 million monkeys randomly typing typewriters = 1 shakespeare manuscript created

    monkeys and humans 98% the same, and this new genetic analysis indicates human up to 10% different, or, only 90% the same

    therefore, 98%-90% = 8% difference in monkey versus human random shakespeare manuscript creation

    8% of 1 million is 8,000

    therefore, 8,000 more monkeys than humans are required to produce one shakespeare manuscript

    it's a scientific fact folks

    (as well as all other "facts" gleaned from this 10% number in the article)

    --
    intellectual property law is philosophically incoherent. it is your moral duty to ignore it or sabotage it
  7. Re:God vs Man by timmarhy · · Score: 5, Funny

    picture someone sticking they hands over their ears and yelling LALALALALA I CANT HEAR YOU, and you will know the religous stance

    --
    If you mod me down, I will become more powerful than you can imagine....
  8. Re:God vs Man by A+beautiful+mind · · Score: 4, Funny

    There are even scarier truths in science. Imagine this:

    100% of the atoms making us up are DIFFERENT. No two person has the exact SAME atoms!!

    Oh please say it ain't true! Say it ain't true! Now I will have to meditate for half an hour in my religious beliefs just to be able to breath again!

    --
    It takes a man to suffer ignorance and smile
    Be yourself no matter what they say
  9. Re:chimpanzees=98% human by RetroRichie · · Score: 5, Funny

    We already found him. And we elected him President!

  10. Re:Actually by Anonymous Coward · · Score: 1, Funny

    Right, because when I want the latest news on evolutionary biology, the first place I go and look for it is a creationist spew site. Just like how I get my facts on the safety of nuclear power from greenpeace, and my intimate knowledge of global warming from exxon-mobile.

    Please, lets try and keep the lunatic fringe off slashdot.

  11. On The Origin of Slashies... by Anonymous Coward · · Score: 5, Funny
    Creationists on slashdot? I thought this place only had smart people.
    And where do you think these smart people came from? Unless you seriously believe that they spontaneously appeared on slashdot fully-formed, they must have evolved from something ;)

    1. Re:On The Origin of Slashies... by mrRay720 · · Score: 3, Funny

      >Unless you seriously believe that they spontaneously appeared on slashdot fully-formed, they must have evolved from something

      My ancestors visited Digg? No, say it ain't so!!! It can't be, anyway, there are no itermediary fossils!

  12. Re:Good Science meet REALLY bad math by Boghog · · Score: 4, Funny

    OK, according to the Chromosome FAQs:
    http://www.ornl.gov/sci/techresources/Human_Genome /posters/chromosome/faqs.shtml
    The X chromosome comprises ~5% of the genome while the Y chromosome is ~1%. Since women are XX and men are XY, men and women differ by ~6%.
    If chimps are only 2% different from men, then men are more closely related to chimps than women. QED

  13. The secret... by SIInudeity · · Score: 2, Funny

    gtagcgtagatagctctagctagcttaggagcttagaggcgcttagatcg cgatcga

    1. Re:The secret... by Anonymous Coward · · Score: 1, Funny

      haha! Your comment was too clever for Slashdot! :p

  14. Re:chimpanzees=98% human by Anonymous Coward · · Score: 4, Funny

    > And we elected him President!
    Elected?

  15. Re:oblig Steven Wright WTF? by Anonymous Coward · · Score: 1, Funny

    how the hell is this a troll?
    moderator dislikes poster?

  16. Real world example by Jugalator · · Score: 4, Funny

    Example of a 10% different human.

    --
    Beware: In C++, your friends can see your privates!
  17. Re:Actually by matw8 · · Score: 2, Funny
    exxon-mobile
    They make those petrol powered cell phones right??
  18. Re:Actually by polar+red · · Score: 2, Funny
    Heck, the human brain is 70% water, does that mean the head is "pretty much" like a 1/3 empty coffee pot?

    I would argue that for many people 70% of the brain is air.
    --
    Yes, I'm left. You have a problem with that?
  19. Re:God vs Man by bazorg · · Score: 2, Funny
    For example, how should a true Christian receive this news?

    I'm not religious, but let me try: Adam was created by God using mud from a river bank. The materials available in common earth are not different from the ones found in a human body.

    All the matter in the Universe was concentrated in one single place and time, then it exploded and eventually became all the stars, planets and creatures we know today. God is everywhere and we all are part of God.

    Simple creatures evolve to become complex creatures. If we have a really close look, the basic components and the instructions (DNA) are similar across species. The best mutations survive, the others fail and do not carry on in the gene pool. God is perfect, Nature is perfect.

  20. Re:Natural Selection no longer applies to humans by oliverthered · · Score: 5, Funny

    Unfortunatally it seems to be just the kind of humans you wouldn't want running around the place that are having lots of children nowadays.

    --
    thank God the internet isn't a human right.
  21. Re:Natural Selection no longer applies to humans by gstoddart · · Score: 3, Funny
    All of this allows a few 'sexually preferred' individuals to contribute to the next generation's gene pool in a significant way, first in that certain individuals have more opportunity to have children - say, because of attractiveness - and second, that the number of kids is a personal choice that varies greatly.

    Well, anecdotally, I have observed that a lot of stupid and ugly people are having children. I don't meant his flippantly, I mean it literally.

    I think the grand-parent has a very good point -- the people who are producing children are not being selected based on attractiveness, or ability to earn an income, or any form of "breeding of the fittest", they are being selected on their willingness to put out. I know in my high school, the biggest idiots were the ones having children. Repeatedly usually. Sometimes, they were helping to perpetuate a cycle of poverty of kids being born to poor, uneducated people, and having very few opportunities in life.

    Modern society insulates people from any of the good parts of natural selection. Between welfare footing the bill for the kid, or irresponsible people who go around serially knocking up everyone they come across (no pun intended ;-), I see a lot of evidence that the least suitable are the ones contributing to the gene pool. Conversely, a lot of the intelligent/educated/productive people are choosing to have fewer or no kids.

    I would argue that your point of "sexually preferred" people is more like "sexually available" -- they're not the most attractive or desireable people, they are whoever is handy. There's just way too many people peeing in the gene pool.

    Cheers
    --
    Lost at C:>. Found at C.