Slashdot Mirror
Nicotine Is the New Wonder Drug
Fantastic Lad sends us to Wired for a story on the upside of nicotine. Researchers are developing drugs based on nicotine that may prove beneficial for brains, bowels, blood vessels and immune systems. "Nicotine acts on the acetylcholine receptors in the brain, stimulating and regulating the release of a slew of brain chemicals, including seratonin, dopamine and norepinephrine. Now drugs derived from nicotine and the research on nicotine receptors are in clinical trials for everything from helping to heal wounds, to depression, schizophrenia, Alzheimer's, Tourette Syndrome, ADHD, anger management and anxiety." A separate story talks about nicotine warding off Parkinson's disease.
I guess that you're intimating that the cigarette companies are pushing this.
I'm sure that it won't be administered via a cigarette because the delivery system is important too. In the case of cigarettes, the delivery mechanism causes more harm than the nicotine helps. After all, antibiotics are good medicine but you wouldn't administer them by putting them on the tip of a knitting needle and jamming it into your eyeball.
I can kind of vouch for this. Usually when I have my first smoke of the day I have to use the can soon after. I always thought they just put laxatives in cigarettes..
Today's Tomorrow is Yesterday's Future! --- "Where Ever You Go, There You Are" -- Diablo 1
You're overreacting. It's all about the dosage and usage.
;).
Lots of people go for botox treatments, and allegedly some of them end up looking better
People consume poisons all the time - capsaicin (in spicy foods), cyanide (in almonds), caffeine, and nicotine. Chrysanthemum is often made into a tea, but it contains pyrethrum which is a "natural pesticide".
In fact, it may be that a lot of smokers are dying more due to the radioactivity than the nicotine or tar.
wiki: "One study found that tobacco grown in India averaged only 0.09 pCi per gram of polonium 210, whereas tobacco grown in the United States averaged 0.516 pCi per gram."
"In support of this hypothetical link between radioactive elements in tobacco and cancer is the observation that bladder cancer incidence is also proportional to the amount of tobacco smoked, even though nonradioactive carcinogens have not been detected in the urine of even heavy smokers; however, urine of smokers contains about six times more polonium 210 than that of nonsmokers, suggesting strongly that the polonium 210 is the cause of the bladder carcinogenicity, and would be expected to act similarly in the lungs and other tissue."
This certainly sounds too good to be true. Makes me wonder who's funding the research.
With a response like that, it makes me wonder if you even care if the research is accurate.
I think they are planning on modified nicotine. Anyway, considering all the stuff in cigarettes, I don't think nicotine is the worst part - it's just the part that makes it hard for you to quit.
Personally, I think the idea of modified nicotine may hold promise for many, but for those who smoke, the concept is somewhat akin to taking caffeine tablets instead of enjoying (or sharing ) that great cup of coffee. To the extent it works, life becomes a little bit less enjoyable. And less social.
I smoke. Not because I suffer from an addiction to nicotine, or an innability to change any number of related habits, but because I choose to. And I derive great pleasure from it for a large number of reasons. I have, on occasion, cut back, or stopped entirely for weeks or months at a time, but I think that was due in most part to suffering the effects of a good habit gone bad. Too much of anything is bad (or bad for you, if you prefer). The ability to make that distinction is important.
The benefits of nicotine for those suffering schizophrenia I found notable. Anyone familiar with the disease knows that smoking "relaxes" schizophrenics. I have a family member who has suffered from schizophrenia for most of his life. Watching him suffer from the disease is one thing, but seeing him endure the effects of the varying regimen of (mostly ineffective) drugs was even more painful. Personally, I'd prefer that he have a cigarette from time to time to make his (and others) life more bearable.
For anyone that has opinions on smoking that borders on the hysterical, I'd suggest they lighten up. Or better still, light up once in a while. There are many things in life that are good for you in small amounts, but dangerous or poisonous at higher levels. Put another way, you'd be better served by not moralising your (and everyone else's) choices and instead, pick your favourite poison and enjoy it responsibly. Besides, what else are you going to do after sex? Peel an orange?
Who said that cigarettes had to be the delivery mechanism? I'm sure cigarette companies have a large stake in tobacco farms, and may even own them. Seeing the heavy legislation and the decline in smoking, they are doing what any well-run company would do, which is to pursue other markets. The nicotine has to come from somewhere.
LS
There is a fine line between being a cultivated citizen and being someone else's crop. - A. J. Patrick Liszkie
,,,but breathing in tar and particulate matter does not. And even if they find some beneficial uses for nicotene, its use must still be weighed against its effects as an addictive stimulant, including constricting the arteries and making people more susceptible to stroke and heart attacks.
No matter what uses they find for nicotene, you're not going to suddenly make smoking healthy, so it wouldn't matter even if the tobacco industry was funding this.
If it's for-profit but free, you're not the customer -- you're the product (e.g., the Slashdot Beta's "audience").
What they are doing is looking at drugs which are derivatives of nicotine. Thus they can patent them and charge you $5/pill.
He's really quick to realize that. Paracelsus said that some time in the 16th century
We're going to replace a $2.50 pack of cigarettes with a $400 bottle of pills, and declare victory! I would be more than willing to bet that even if you factor in the eventual risk cost of cancer and other smoking related diseases, it might still come in cheaper than the cost of exotic drugs based on nicotine. The moral of the story is, smoke up to avoid depression, and hope science comes up with a cheaper pill to cure cancer.
This is my sig.
You also don't eat moldy oranges if you have a bacteria infection. You don't drink rusty water if you have an iron defiancy. Smoking is a horible way of reaping any benefits of nicotine, first you get an uneven doses of it that is difficult to measure, there is tar that sticks to your lungs, There are a bunch of other hazardous chemicals that are released from the burning process. The same for "Medical" Marjuna, they give you a joint to smoke. That is stupid unmedical it is only an excuse to take the drug reconationally, just get a crooked doctore to fill you out a prescription. LIke most drugs there is a fine line between useful and harmful, and lot of the time is is a balance that the drug will do more good then bad at the correct dose. Smoking will be more harm then what the Nicotine will offer good thus it is still stupid to smoke.
If something is so important that you feel the need to post it on the internet... It probably isn't that important.
You gave up smoking? There's half your problem!
It's in your language - you see not smoking as a sacrifice. Every time you mention to anyone that you're giving up, you subtly reinforce to yourself the idea that you are depriving yourself of something pleasurable.
I stopped smoking instead of giving up. I made a point of referring to it in that fashion. The thing is, because of that attitude, I made sure I didn't feel like I was missing out on anything.
Giving up smoking is hard - I tried it several times. Stopping smoking is much easier.
Ahh - My eye!
The doctor said I'm not supposed to get Slashdot in it!
"All substances are poisons; there is none which is not a poison. The right dose differentiates a poison from a remedy." Paracelsus (1493-1541)
It is. And many prescription pain killers (Vicodin, Oxycodone) do not differ significantly from heroin in their effects. Most drugs used to treat ADHD do not differ significantly in their effects from crystal meth. Drugs used to treat depression (SSRIs) aren't significantly different than XTC in their effects. And?
It's not the drug, it's how its used that counts.
My blog
hahahahaha, and whomever modded you offtopic is a real lame-o.
Clearly, said moderator has an infected humour gland. Maybe we give him a dose of antibiotics via a knitting needle?
blah blah blah
It isn't just that...for many of us, smoking is FUN. I wish to hell it wasn't bad for you...if it weren't, I'd go back to it. It just was so natural to be in a bar, have a drink in one hand...smoke in the other. It also appeals to the 'firebug' in many people. Half the fun to me was the lighting up part.
Also, was a neat way to introduce yourself to a woman...even not smoking any more, I often carry a lighter to light a smoke for her when she pulls one out.
I'm sure some people...many in fact...are very hooked to nicotine..but, not everyone. Whenever I quit (and I've gone for years at a time)..the first 2 days are a PITA...but, not that big a deal after than. I didn't really smoke 'cause I NEEDED ONE....I did it because it was fun and an enjoyable activity for me.
I don't think anyone is smoking because it "looks cool" or promotes an image. Most people I think smoke because they enjoy it and it is fun. If they came out with a harmless cigarette....I'd start smoking again immediately.
Light travels faster than sound. This is why some people appear bright until you hear them speak.........
Hi there. Your argument for the legalization of marijuana fails to even be coherent. Please put down the bong. You can't say "See?!?! Nicotine is used by the mentally ill, according to this doctor, so Marijuana is good!" There isn't any nicotine in marijuana. It's called THC, and other assorted cannibinols. Just how did the article demonstrate the idiocy of marijuana being on Schedule I?
I am a marijuana user, and am all for legalization, but it's people like you who spew any garbage rhetoric that you can, even when it makes you just look like a stupid teenager that make it harder.
Cheers mate... It's people like you who make me want to stub out my Cigarette out in your eyeball
It's not logical it's an addiction. Nothing at all to do with higher brain function
Everything to do with a chemically induced feed back loop in the risk/reward part of the brain.
I'm not looking for sympathy or understanding, but you and the pitchfork wielding mob you represent
can burn in hell as far as I'm concerned. Smokers have been kicked out of everywhere and it seems that
it's now socially acceptable to harass us on the street!
Buggerit
Grrrr
Help! help!, the termites are eating my DRAM!!!
I'm not sure why this is so hard for some people to swallow. Most drugs that have such an obvious and strong effect on people and have been tested on millions with few adverse effects (all the bad effects of smoking come mostly from the smoke + chronic use—the nicotine merely makes it addictive) usually yield other valuable research output.
I don't see any reason to let emotional value judgments get in the way of potentially valuable medical applications. Let's turn that frown upside down and make a negative into a positive!
Disclaimer: No I'm not a drug company representative nor a smoking advocate.
but have you considered the following argument: shut up.
Well, the difference here is really that drinking wine daily promotes general heart health and can be beneficial to all. If you are not suffering from Alzheimer's, depression, schizophrenia, ADHD, or anxiety, taking nicotine based drugs probably wouldn't really help you much, if at all. That would be like a non-cancer patient taking interferon, or someone who isn't diabetic injecting themselves with insulin. Just because something is beneficial to certain ailments doesn't mean it also promotes general good health.
People that hear some scientific claim, inject it with their own pseudo-science, do no actual research on a substance, and just start taking it without any real medical referral are asking for trouble...
"But this one goes to 11!"
The primary asset of tobacco companies is millions of addicted customers.
Since when was nicotine bad for you? How about since the first plant synthesized it as a biological poison, to be used as a defense against insects and competing plants?