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Nicotine Is the New Wonder Drug

Fantastic Lad sends us to Wired for a story on the upside of nicotine. Researchers are developing drugs based on nicotine that may prove beneficial for brains, bowels, blood vessels and immune systems. "Nicotine acts on the acetylcholine receptors in the brain, stimulating and regulating the release of a slew of brain chemicals, including seratonin, dopamine and norepinephrine. Now drugs derived from nicotine and the research on nicotine receptors are in clinical trials for everything from helping to heal wounds, to depression, schizophrenia, Alzheimer's, Tourette Syndrome, ADHD, anger management and anxiety." A separate story talks about nicotine warding off Parkinson's disease.

10 of 439 comments (clear)

  1. Oh great by Anonymous Coward · · Score: 5, Funny

    quit smoking after 15 years. What a bitch. And NOW they say that the nicotine is good?

  2. Re:Oh great by niceone · · Score: 5, Funny

    Stop making me smoke you damned scientists!

    I'm surprised they are letting lab beagles post on slashdot, is it the result of some animal rights campaign?

  3. Re:Suspicious at best. by canUbeleiveIT · · Score: 5, Insightful

    I guess that you're intimating that the cigarette companies are pushing this.

    I'm sure that it won't be administered via a cigarette because the delivery system is important too. In the case of cigarettes, the delivery mechanism causes more harm than the nicotine helps. After all, antibiotics are good medicine but you wouldn't administer them by putting them on the tip of a knitting needle and jamming it into your eyeball.

  4. Re:Suspicious at best. by Anonymous Coward · · Score: 5, Funny

    Depends on who I was administering it to...

  5. The real problem by stormi · · Score: 5, Interesting

    The idea is that nicotine releases happy chemicals in your brain. I think we've already known this for a while - it's why it's so hard to quit smoking. Now they are realizing that happy chemicals can treat some psychological disorders. Plausible. However, there is a problem with this theory that we've recognized for a long time. When we artifically create these chemicals in the brain via medications or other chemicals and drugs, we get used to having the feeling. Then, in ordinary situations where we are supposed to experience happiness (ex. a day off, a sunny day, a good dessert, a good song) we don't feel anything. This leads further into depression because people literally cannot find happiness in activities they once found enjoyable. Any of the "happy chemicals" that might go off naturaly are so negligible compared to the constant chemicals caused by the drugs that the good experiences may just as well have never happened. So, nicotine makes you happy? Probably. Can help with certain mental disorders? Again, probably. But should it be used / is it the best solution? That is what's debatable.

    --
    "if only i had known i would have been a locksmith." -albert einstein
  6. better than SSRI? by lawpoop · · Score: 5, Interesting

    I had a bout of depression last year and I saw a psychiatrist. I went over my life history. At the end of the session, he recommended a cocktail of 3 different drugs! Apparently because I had had a manic episode once in my life when I was in high-school, I was a manic-depressive. I needed one drug for the depression, one for the mania, and some other one. Jesus Christ.

    I stopped seeing him. I was looking into 'legal' highs for depression, such as St. John's Wort and

    Since I also had problems concentrating, I tried smoking for the nicotine. I found that it really helped with my anxiety. I took a smoke after work, I relaxed, and then moved my bowels. I felt calm and focused rather than frenzied and harried. Things were right on course instead of all over the place. I've since given it up, however, since I started coughing.

    I know smoking destroys your lungs gives you cancer after decades. My maternal grandparents died of cancers in their 60s, probably from smoking. All the people I try to turn on to smoking tell me that. But what are the long-term effects of taking anti-depression or anti-anxiety medication for decades.

    It seems to me that cigarettes are a relatively cheap and simple anti-depressant. Although there are long term health consequences, we don't really know what the damage is from decades of wellbutrin. Of course, Big Pharma would rather have us rely on them for anti-depressants than use a simple plant that we could grow ourselves... Hey, that sounds familiar.

    --
    Computers are useless. They can only give you answers.
    -- Pablo Picasso
  7. Re:Wait ..... by JargonScott · · Score: 5, Funny

    I'm surprised at your typing prowess given that type of activity. o.O

    --
    Nuke Gay Whales for Jesus.
  8. New nicotine drugs, for a healthy you.... by bodland · · Score: 5, Funny

    Packaged in a 20 dose per container. New fashionable "inhaler" delivery system. Regular, 100 and 120 mg sizes. To take the new drugs you light the end of the inhaler tube and inhale the refreshing vapor. The dose burns with a pleasing aroma and relaxing patterns of vapor. 20 doses, take as needed 20 times per day or more. Packed in soft of hard pack box and cartons. Available at most gas stations. Menthol and other flavors available. NOW over the counter!

    Welcome to a healthy new you.

  9. Re:Suspicious at best. by asliarun · · Score: 5, Insightful

    Not exclusively nicotine. They sell an image. Nicotine is just a nice side effect that keeps people physically addicted to their stuff. Sure, but so does alcohol or any other legally addictive substance. My point here is not to start a comparison war or a flame on which drug is healthier/less addictive etc. I'm just trying to point out that there is a LOT of hypocrisy surrounding cigarettes and smoking. My guess is that this hypocrisy mainly arises because smoking has now become socially unfashionable and even a taboo, at least in the US. Let me put it another way: If the same study was done about say, the beneficial effect of wines or alcohol in general, i bet you would see a tiny fraction of comments making snide remarks about the validity of the test and about the funding agency. Yes yes, I know, the tobacco industry is evil and has a history of funding shady science, but I still feel that the scorn being shown on /. is disproportionate. Heck, even a hard drug like cocaine or LSD wouldn't get this much opposition and sarcasm.
  10. Re:Suspicious at best. by milamber3 · · Score: 5, Informative

    You should really know more about a subject before you go on spouting things like "You can be sure the tobacco industry is funding this research." A large portion of this funding is coming from the NIH and one of the main areas of study is smoking cessation. That most certainly does not benefit the tobacco companies. In addition, none of these studies would suggest a cigarette, dip or chew as the route of administration so once again no benefit. If anything, the pharm companies stand to gain while the tobacco companies stand to lose because the drugs in question are all synthetic nicotine like substances that are patented and solely under big pharma control.