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Experts Claim HIV Patients Made Non-Infectious

Misanthrope writes to tell us that Swiss scientists are claiming that with proper treatment HIV patients can be made non-infectious. "The statement's headline statement says that 'after review of the medical literature and extensive discussion,' the Swiss Federal Commission for HIV / AIDS resolves that, 'An HIV-infected person on antiretroviral therapy with completely suppressed viraemia ("effective ART") is not sexually infectious, i.e. cannot transmit HIV through sexual contact.'"

69 of 394 comments (clear)

  1. I'm not infected baby... Really.... by bagboy · · Score: 5, Funny

    I promise...... Trust me....

    1. Re:I'm not infected baby... Really.... by KublaiKhan · · Score: 5, Interesting

      It's worth noting that this finding is only valid if there are no other STIs present--so if you've got the clap -and- HIV, you'll still be more likely to transmit it.

      Wasn't there an article a short while ago about how treating concurrent STIs also tended to decrease the rate of AIDs infection in an area? Perhaps this is related?

      --
      In Xanadu did Kubla Khan
      A stately pleasure dome decree
    2. Re:I'm not infected baby... Really.... by Malevolent+Tester · · Score: 3, Insightful

      Given that the same high risk behaviour that spreads HIV also spreads other STDs, I can't see this will actually help much.

      --
      If you haven't made a developer cry, you've wasted a day.
    3. Re:I'm not infected baby... Really.... by KublaiKhan · · Score: 4, Insightful

      Not all people who contract AIDS are engaging (voluntarily, anyway) in high-risk behavior.

      Also, treating STDs would provide opportunity for conversion of high-risk behaviors into lower-risk behaviors, e.g. you're in the office anyway, why not have a little talk about safe sex while you're there?

      Hence, treating the other (usually more obvious) STDs would presumably impact the treatment of AIDS for a number of reasons--counselling, earlier detection, and possible reduction of the viral load to a less-dangerous level.

      --
      In Xanadu did Kubla Khan
      A stately pleasure dome decree
    4. Re:I'm not infected baby... Really.... by noidentity · · Score: 4, Funny

      I'm not infected baby... Really.... I promise...... Trust me....

      Given that this is on Slashdot, that's pretty much a given.

    5. Re:I'm not infected baby... Really.... by ricebowl · · Score: 4, Funny

      Also, treating STDs would provide opportunity for conversion of high-risk behaviors into lower-risk behaviors, e.g. you're in the office anyway, why not have a little talk about safe sex while you're there?

      So...what is it that you do in your office?

    6. Re:I'm not infected baby... Really.... by Anonymous Coward · · Score: 2, Funny

      No, he means having sex with your mother.

    7. Re:I'm not infected baby... Really.... by lessthan · · Score: 2, Insightful

      If you have HIV, that doesn't mean you have to stop having sex. It means you have to start using condoms (which you should have been doing anyway!!). The article is saying that so long as you take your meds, you won't give it to a partner. For example, a HIV positive women slips on broken glass and now there is bloody glass everywhere. Her husband helps her up and gets cut too. It is very unlikely that he'll get HIV.

      --
      Space Shuttle was a program that strapped humans to an explosion and tried to stab through the sky with fire and math
    8. Re:I'm not infected baby... Really.... by VoidCrow · · Score: 2, Funny

      Speak for yourself. Oh, hang on, what am I saying?

  2. Old News by Anonymous Coward · · Score: 5, Funny

    I have HIV and I haven't used a condom in several years with dozens of sexual partners.

    Nobodoy has called me back saying they have AIDS, so I must not be infectious.

    1. Re:Old News by Anonymous Coward · · Score: 5, Funny

      Reminds me of Mitch Hedberg's "indirect" AIDS test.

      "Hey Joe, do you know anyone who has AIDS? No? Cool... 'cause you know me."

    2. Re:Old News by Anonymous Coward · · Score: 5, Insightful

      Everything is funny. Some things just aren't funny to you.

    3. Re:Old News by krotkruton · · Score: 2, Informative

      Sorry, but it's been over 22.3 years since the AIDs epidemic started, so it's acceptable to make fun of it. Just ask Jared.

  3. Encouraging news by KublaiKhan · · Score: 2, Insightful

    One can only hope that the treatments can be made available at a decent price, so that the folks who are most likely to pass it on--poor people who don't know how to use contraception and the like--will be able to be treated.

    Unlikely, though, I dare say...those drug companies do love their income.

    --
    In Xanadu did Kubla Khan
    A stately pleasure dome decree
    1. Re:Encouraging news by nonsequitor · · Score: 3, Interesting

      It is my understanding anti-retroviral treatment is very expensive. For this to have any effect on the spread of HIV, every infected person in the third world needs treatment.

      I wonder how many months in Iraq it would cost to do something like that.

    2. Re:Encouraging news by KublaiKhan · · Score: 2, Interesting

      Thus my comment about the drug companies.

      Though IIRC, there was a recent article about a couple of patents being overturned for some AIDS drug or another; this would make (presumably lower-cost) generics available.

      My personal opinion is that these drugs (of all kinds) would likely be a lot less expensive if the companies that made them did not advertise all over the place--because, frankly, they're all only available with prescriptions anyway; why not trust the doctors to prescribe what's best for the patient, rather than what's in this month's issue of People?

      --
      In Xanadu did Kubla Khan
      A stately pleasure dome decree
    3. Re:Encouraging news by Anonymous Coward · · Score: 2, Interesting

      "-poor people who don't know how to use contraception and the like--will be able to be treated."

      So you think it's likely that these people you describe, the ones who don't know how to use a condom or reliably take birth control pills, will be able to take their antiretrovirals, usually several times daily, and not appreciably miss doses to keep their viral load down for at least SIX MONTHS (yes - i read the article) is the more likely outcome?

      This is an intersting finding, but not what you think it is.

    4. Re:Encouraging news by Tsiangkun · · Score: 4, Interesting

      Those were my first thoughts, make this available as a way to protect the community.

      If we can do bullshit like keep two ounces of mouthwash off a plane, while letting one ounce on, then we can get effective disease prevention to our population.

      Then I thought more, since I live in America where reality based communities don't alway align with the faith based government.

      My government hates sex. My government hates gays. My government thinks AIDS is a gay disease. AIDS is a sexually transmitted disease, and my government is not going to subsidize someones sex life.

      My government will do nothing but continue to say abstinence is the only way to remain disease free.

      Captcha = unfair

    5. Re:Encouraging news by Anonymous Coward · · Score: 4, Informative

      Actually, having worked in third world medical aid I can say categorically that there is a benefit to the patients receiving these drugs. So it's win win for the people taking the drugs (their quality of life is improved, they live longer) and the community.

      Aids is no longer the death sentence it once was. It's like diabetes, if left untreated it is fatal but it can be treated successfully. If they can just eliminate the transmission aspect, then this scourge will be gone in a few generations.

    6. Re:Encouraging news by Belial6 · · Score: 2, Insightful

      Part of the problem is that often the patient DOES know better than the doctor. I can honestly say that I have not had a doctor do, or say anything to me that I did not already know since I was about 10 years old. I have on the other hand had doctors tell me things that were simply wrong. I'm sure there are some good doctors out there, but the nature of our medical industry leaves most of us diagnosing our own illness. Not out of hubris, but out of necessity.

    7. Re:Encouraging news by nonsequitor · · Score: 2, Insightful

      Wow, thats right up there with putting the infected into concentration camps. Your trolling needs work, it has to be believable that you personally hold that opinion to elicit the shrill responses a good troll will get.

      My point above was that this is not viable for mass treatment and will only be available to the privileged elite like Magic Johnson. Though you are technically correct about the effectiveness of your method, you've raised a fundamental ethics question: Is saving the species from disease worth it at the cost of our humanity?

      This is fundamental to the ethical debate behind many emerging technologies like embrionic stem cell research, where the answer is unclear to many. However, I think its safe to say that compulsory mutilation has a lot less grey area.

    8. Re:Encouraging news by tezbobobo · · Score: 4, Insightful

      You may have read the article but your missing some pieces of the puzzle. The people who catch and spread aids via condom misuse are those who do not care in the 'heat of the moment'. Birth control pills don't enter the equation because they have nothing to do with the spread of Aids, except perhaps to persuade those who do not have them to use a little more abstinence.

      The best way to deliver these drugs would be to use a system similar to implanon if available, whereby any drug are implanted subdermally and released slowly. The benefit is that by having a steady stream lower doses can be used. Secondly, governments are constantly comparing the future costs of care for incapacitated aids patients to current treatment cost. When a sufficiently effective solution presents itself - if the cost benefit is good - governments *will* pay for it.

    9. Re:Encouraging news by Belial6 · · Score: 2, Insightful

      Really? So, explain to me what happened to the the test to check for Chicken Pox that seemed to disappear between the time that one doctor told my wife that there was no test to see if a child had chicken pox, and the time that a second doctor schedule the test at the lab. Given that I have had many people express that they have had the same kinds of experience with doctors telling them things that are incorrect, your qualifier of 'competent' must only apply to a small percentage of them.

      Of course there is the alternative that the incorrect information that many doctors give to their patients is not because they got it wrong, but because they are simply lying. I have a hard time believing that any pediatrician is unfamiliar with the test to see if a child has been exposed to chicken pox.

      Don't think that I am characterizing people in the medical field as evil. They are simply human. That means that sometimes they make mistakes, cover their asses, and take the path of least resistance. They are simply human. They sometimes do good work, and sometimes do bad work, just like people in any other field. Thinking that they are somehow infallible gods, just because they are doctors is naive at best. Unfortunately because they are in positions of power, they will often fall prey to the human failures that manifest with people in positions of power.

    10. Re:Encouraging news by shihonage · · Score: 3, Informative

      Actually, around 47% of all people diagnosed with AIDS were infected with HIV through male-to-male sexual contact, while people exposed through heterosexual contact comprise around 17% of the total. Male-to-male sexual contact probably caused the majority (66%) of infections in white people living with AIDS. It's not "faith", it's "fact". When political correctness stands in the way of science it becomes a disease in itself. A mental one.

    11. Re:Encouraging news by sayfawa · · Score: 2, Insightful

      I agree. And I'd just like to add that another couple of problems with doctors is that,
      1) many seem to think they are done learning once they finish med school and get their practice going. They don't seem to have the research mentality that other scientists do. And,
      2) they have to deal with so many idiots who don't know or care about their bodies that they think we are all like that. And instead of giving us "dangerous" information that they don't feel we need to know they just give us the meds and send us on our way.

      --
      Free the Quark 3 from asymptotic confinement! Bring your charm! Don't get down! All colours and flavours welcome!
    12. Re:Encouraging news by Mr.+Underbridge · · Score: 4, Insightful

      or if your symptoms were so nondescript it could be a 100 things.

      Well shit. If you rule out the hard cases, an RN could do anything a general practitioner doctor can.

      That SHOULD be why they make the big bucks - the hard cases with confusing or nondescript symptoms. As a practical matter, most of them bail on anything they can't churn through in a 15 minute office visit. Even specialists are starting to suck. They can't be bothered to do any research, if the usual blood work doesn't solve the problem, they'll just roll through tests until they get lucky, or you just give up. Or die, maybe. And if your symptoms fall between specialties, you're completely fucked, because they can't be bothered to fill in knowledge gaps with...again...research. Which would help them put evidence together with their own expertise to make a successful diagnosis OR at least find the right specialist. But for most doctors, forget it.

      i'd say the most likely case here is that the doctor is right, and you just THINK you know better.

      I can back up the OP. I had a problem for 8 years that multiple doctors consistently failed at. None even came up with a guess, just saw me for an appointment, sent me off for the wrong test, told me they didn't know what it was, and referred me to someone else. When the 5th doctor in the chain referred me to the first, I said to hell with it and decided to live with the symptoms. I eventually got sick of that, and successfully diagnosed it myself. With Google, effort, and a brain.

      I feel sorry for others though. I'm a scientist and have good research skills. People shouldn't have to be forced to do their own medical care.

    13. Re:Encouraging news by king-manic · · Score: 4, Interesting

      I've seen this comment before on /. as well as similar comments about the infant mortality rate being higher in the US than any other country (which means the US healthcare system is teh suck). When these figures are quoted, are you people including the people who live in the ghet-to in large US cities? People who don't see a doctor on a regular basis and use the hospital E.R. when they have a backache? Are you also including all of the children under 18 who are accidentally shot in drive-by shootings? If so, yes, the US healthcare system looks pretty bad. We have a lot of people who don't survive infancy or don't live to see age 21. But that's not due to our healthcare system. It's due to crappy inner-city living conditions and too many gang-bangers who have no respect for other people's lives.

      Our healthcare system in the US works quite well if you have a job and insurance (that's one hell of an incentive to get out of bed in the morning and drag your ass to work!). I have personally witnessed "no expense spared" treatments which saved the lives of friends or their children. I work in healthcare and I get to see firsthand the technology the doctors have at their disposal to diagnose and treat health issues. Newsflash: Canada has slums too! In fact little towns called reserves are every bit as bad as any ghetto in the US. The best country to compare the US to is Canada. The reason our slums aren't as large and widespread is partially due to universal health care. Medical expenses are a leading cause of bankruptcy which is a major cause for poverty. Without this sword hanging above your family it's a much more peaceful and healthy place. Ethnically and culturally Canada resembles the US. If you did an analysis the key difference is single payer health care.

      And no I haven't watched Micheal Moores propaganda piece, however Canada is an example of how even bureaucratic government wrangling does not obliterate the benefit of universal health care. Of course We lack the sheer incompetences that is the current US admin. Perhaps if it was instituted while enough of the Bush cronies lead the various government agencies, it'd fail as spectacularly as FEMA did during Katrina.

      The US problem is they believe free market fixes everything. However this ideology is flawed as very few things exist in an ideal free market. The US health care system isn't a truly free market. Canada's system is probably closer to an ideal free market then the US system. We have a single payer, pay as you go system. Right now it's crunching under a worse case scenario but that will fade soon. All tax payers pay a set amount, and most services are private. From hospital supply companies, drug companies, the MRI scanning company, to the GP. All private businesses to negotiated with a central body for payment. It gives the people a better deal and actually reduces bureaucracy vs the US system. Where there are dozens of insurance companies all doing essentially the same jobs all working off the same actuary tables, in Canada we just have a central body to regulate our finances for health. The goal of the organization is singular "to make people better" while the US system has mixed goals of "produce most profit" and "to make people better". The lack of a profit margin at every level also helps. Canada health does not aim to make 60% profit off your treatment before factoring the profit of all private companies involved. This alone would negate any and all efficiencies the US systems may have. State of the art treatments are invented and used here as well. Likely similar to the ratio of our populations.
      --
      "There are more things in heaven and earth, Horatio, than are dreamt of in your philosophy."
    14. Re:Encouraging news by shihonage · · Score: 3, Insightful

      The post I was replying to WAS about the United States. Sigh... it's not our job to police the world. Now that we reestablished the scope - the statistics, sure, you can put a spin on it by omitting the comparison to the 17% of heterosexuals that contract the disease, but that's all it is - a spin. The factual truth is, as far as statistics go, gays comprise the largest single group by far, and yeah, people might say, that DOES make it a gay disease, and yeah, they wouldn't be unjustified in that evaluation. The negative side of the Internet is that people are tempted to try to spin the numbers. The positive side, however, is that anyone with a modicum of critical thinking can look them up. This reminds me of kneejerk reactions to that Japanese guy who implied that your average woman's upper body strength is inferior to that of an average man. Oh no, how dare he cite facts ! That's so rude ! Let's just lie to ourselves instead, it makes us warm and cozy inside (rolls eyes).

    15. Re:Encouraging news by gordo3000 · · Score: 3, Informative

      Aids is a death sentence. you just have to pick your time horizon. people who have been on antiretrovirals for 15 years are now feeling the effects of basically putting a poison in your body daily for so long. they have severe medical problems that are very expensive to treat and find themselves unable to function. 40 year olds look like they are 65 and have health problems on a similar scale. it's just when you die of kidney failure at 45 have 18 years on the drugs, we don't say AIDS killed you, but that is hiding the issue that still exists.

    16. Re:Encouraging news by Virtual_Raider · · Score: 2, Interesting

      I have a whole lot more respect for a good auto mechanic or other problem solvers than your average doctor. Auto mechanic isn't done with your car until it runs right. Networking guy isn't done until your computer has a connection. Doctor can keep running tests forever.

      There is a fundamental difference between the two activities: ANY technology-related problem can be solved because the whole system is human-designed. It's been understood from the beginning and the goals and functions of every single element are known because it was made to be so. You can read the documentation about it and you will know whithout a doubt how it's supposed to work so you can find out why it doesn't.

      We currently know a great deal about the way a human body does, but it's complexity is vastly superior to that of any known machine, and it's full of parts we don't know how they work, why they work, or even what are they supposed to do. Difficulty of ruling out failures in this environment is orders of magnitude higher. And I am not even counting in infections by external entities such as virus, bacteria, fungi and the like.

      --
      +Raider of the lost BBS
    17. Re:Encouraging news by Maria+D · · Score: 2, Informative

      We have a running joke in my family, "Never go to doctors until you know your diagnosis and have researched the treatments." If you look at statistics of how many people die to medical mistakes per year, it's quite scary. I have many anecdotes about my family members dying, or almost dying, to easily avoidable medical mistakes or just laziness of diagnostics. And other cases where doctors were just greedy ("business-like"? hmmm).

      My kid goes to doctors less than once a year, and still she accumulated a few ridiculous examples. Once a doctor was strongly pressing for a surgery - and when we equally strongly asked for alternatives, and she explained that yes, we could try a course of antibiotics, but "it will take the whole three or four days, and we could do the surgery today." I could almost see the dollar signs in her eyes. A dentist wanted to do some major procedures under general anesthesia - luckily, we knew that baby teeth should soon fall out and they just started to deteriorate before falling out (like they often do), so we saved the kid the general anesthesia and us several thousand dollars - the teeth fell out within a few months and the next visit to (another) dentist there were no problems. I went to a neurologist with some headaches, and she told me that, first, she gets headaches more often than I do (relevant!) and second, she can prescribe a brain scan (MRI I think) as a helpful treatment (!!!) because it's all in my mind, so once I do an MRI and know it's clear, the headaches will go away. It turned out I had a vision problem and the eye strain was causing headaches, which I figured out later, no thanks to her. I can keep telling these amusing stories all night. The point is that doctors make a lot of mistakes, and some of them just aren't trying (that guy reading his e-mail while "listening" to me describing symptoms? yeah) and those who are trying are limited in their knowledge and skills, just like the rest of us.

    18. Re:Encouraging news by Wdomburg · · Score: 2, Informative

      Very few people in any field are competent and even those that are can make mistakes or have gaps in their knowledge.

      A few years ago my wife was suffering from recurring miscarriages, so we got a consult with a reproductive endocrinologist. His insightful conclusion? That she was ovulating. Yeah, great detective work there. Anovulatory women aren't a particularly high risk group for miscarriages.

      When we finally did retain a successful pregnancy, it was off to the perinatologist. Twin pregnancy on top of all the other risk factors, suspected monoamniotic as well. The highly recommended, highly respected doctor quoted morbidity rates that were about twenty years out of date and outlined a care plan that included none of the intensive monitoring recommended by contemporary studies. When we offered several articles from credible medical journals, she dismissed it with "I don't have time to read something you found on the internet."

      Thankfully we found a doctor who didn't dismiss her patients so easily (and actually did research of her own to make sure she was abreast of new information when faced with less common conditions.)

  4. AIDS free world by qmaqdk · · Score: 4, Insightful

    If this is true, then it effectively means that the world can be AIDS free in a generation. I'm willing to bet it's not going to happen, though. The drug companies have no interest in this.

    --
    My UID is prime. Hah!
    1. Re:AIDS free world by snl2587 · · Score: 2, Interesting

      Drug companies aside, there's no way this would be used anytime soon in 3rd world countries, so the problem will simply continue to grow there.

      What this needs is widespread proof and then some major government backing. Then, maybe.

    2. Re:AIDS free world by dvice_null · · Score: 2, Insightful

      They only talk about sex. How about drug addicts and dirty needles?

    3. Re:AIDS free world by Bill,+Shooter+of+Bul · · Score: 4, Insightful

      We've had a cure for tuberculosis for quite some time as well as polio, yet they are still around. TB still kills many people and has become drug resistant, because people don't take their meds on a regular schedule. If you don't take your aids medicine on time ( a more complex drug regimen), you will still be infectious. But none of that is particularly new. The new aspect is that they say that its not contagious when you have been on the regimen for a while.

      Now, the optimistic among us would have hopped that those on drug regimen knew they could spread the disease and modify their behavior accordingly. So this announcement should actually have little affect. If you were doing what the doctors told you to do, you weren't spreading the disease same as before. Maybe this would act as a motivation for some people? But it also might cause people to engage in riskier behavior and compound the issue.

      --
      Well.. maybe. Or Maybe not. But Definitely not sort of.
    4. Re:AIDS free world by _merlin · · Score: 3, Informative

      Well the major infection vector for AIDS is sex. In Africa, it's primarily heterosexual sex; in Australia it's primarily homosexual sex; in Vietnam it's primarily heterosexual sex. Either way, AIDS is primarily spread by people having sex. Drug addicts and dirty needles is just a tiny blip on the radar for AIDS.

    5. Re:AIDS free world by matt+me · · Score: 2, Insightful

      Know anyone with smallpox?

    6. Re:AIDS free world by tsotha · · Score: 2, Interesting

      Yeah. I live in the San Francisco area. One of the unanticipated consequences of the AIDS "cocktail" has been a surge in unprotected sex among gay men. From an economists point of view, it's probably a rational decision, but actually eradicating the disease without a vaccine is pretty much a pipe dream.

  5. Wow by Hatta · · Score: 4, Insightful

    Can you imagine the shitstorm that would ensue if they're wrong? It takes a whole lot of balls to not just put your reputation on the line like this, but the lives of thousands of people too. I really hope they're right.

    --
    Give me Classic Slashdot or give me death!
    1. Re:Wow by VGR · · Score: 5, Interesting

      They covered their bases. This is one of the most informative and honest articles I've seen in a long time. They make a point of saying, more than once, that they're not positive a treated person is not infectious, but their certainty is equal to the certainty with which the scientific community asserted in 1986 that kissing cannot spread HIV (an assertion that continues to hold up to this day).

      Interestingly, they are not recommending the treatment for widespread use, because many people have trouble rigorously adhering to a treatment schedule, and even a little slip in the treatment could result in the creation of a resistant strain of HIV. I'd hate to be the doctor who has to pass that judgement: "Before I treat you, how do I know you won't skip an occasional treatment, thereby creating a scourge of humankind that's even harder to treat than the HIV we have now?"

      --
      The Internet is full. Go away.
    2. Re:Wow by Anti_Climax · · Score: 4, Informative

      I've been trying to find a copy of the article for a while, but I seem to remember someone publishing a write up about "Curing" HIV with anti-retroviral therapy.

      Essentially it went like this: By *religiously* adhering to a multi-drug cocktail treatment (3-4 drugs targeting different portions of the viral replication cycle) over the course of 3-4 years the free virus particles would be filtered out of the body by the lymph nodes and T-Cells at varying stages of infection would be broken down, leaving a person HIV free. They would still test as HIV positive as they would still have the antibodies in their bloodstream, but they would no longer be infectious or subject to relapse.

      Obviously starting treatment when still healthy would be preferable, like Magic Johnson did. He was diagnosed with HIV about 3 years after my Father was. Magic Johnson is still alive and healthy 16 years later, but my dad died almost 15 years ago.

      There was also a "Morning After" treatment that showed promise for preventing infection after likely exposure to HIV. It was an 8 week course of drugs similar to chemotherapy but, if completed, had a significant success at preventing infection.

      It's good to see they're still working toward these ends, hopefully they can stop it fairly soon.

      --
      Even people that believe in pre-destiny look both ways before crossing the street.
  6. Its no cure (get it & you're still going to di by crovira · · Score: 2, Insightful

    but it does make life possible for those around you.

    I sucks but its a step in the right direction. (But will any company take the next step; after all, once YOU're dead, the disease is eradicated.)

    Sucks to think like an actuary...

    --
    MSBPodcast.com The opinions expressed here are my own. If you don't like 'em... Think up your own stuff.
  7. Improbable, Not Impossible by thePsychologist · · Score: 2, Insightful

    It's in the article but non-infectious here does not mean it's impossible for HIV transmission during sex. It's only improbable and of course the probability of transfer is unknown - as even in the studies done with these drugs other protection measures were used (of course). Furthermore this is not new; rather it's a statement made by a few experts based on older research. The statement is meant to be a standard taken throughout the healthcare world.

    --
    "What lies behind us, and what lies before us are tiny matters compared to what lies within us." Ralph Waldo Emerson
  8. Re:Your best bet... by KublaiKhan · · Score: 4, Insightful

    You're asking people other than you to change their behavior based on your principles?

    If you can figure out how to accomplish that reliably, then every government, armed service, advertising agency, and school wants to speak with you right now.

    --
    In Xanadu did Kubla Khan
    A stately pleasure dome decree
  9. Re:Your best bet... by MT628496 · · Score: 2, Funny

    Is abstinence really that difficult?
    Not for most of the people on Slashdot
  10. Small pox? by SpeedyDX · · Score: 2, Interesting

    Just like drug companies had no interest in eliminating small pox? There are plenty of diseases to go around, and more of them turn up all the time.

    Admittedly, I'm too young to appreciate the politics that went on when small pox was "eradicated", so it would be nice if anyone can point out what's so different about the small pox issue and the AIDS issue.

    1. Re:Small pox? by fabs64 · · Score: 4, Insightful

      Smallpox? You kidding me? The eradication of smallpox was a time of big governments, big non-profits, and a concerted effort for the greater good not for profit.

      Also, back in the late 1700s, someone couldn't patent a scab off of a cows back.

    2. Re:Small pox? by CatPieMan · · Score: 3, Informative

      Small Pox was eradicated due primarily to an immunization effort that spanned the 19th and 20th centuries. Unlike HIV (as far as I am aware), there are two viruses that appear to the human immune system as the same. One causes small pox, the other causes Cow Pox. Essentially, the immunization to small pox is to expose a person to cow pox. They get a feaver for a couple days to a week (along the lines of Chicken Pox), but then become immune to Small Pox.

      With the Small Pox vaccine, once exposed to the alternative, you become immune to Small Pox. HIV is the opposite, once you are exposed, it will kill you.

      As bad as it was, Small Pox was a 20-60% mortality rate (see wikipedia), which is horrible, but there was a chance. HIV is a 100% mortality rate, it just takes a bit longer. If we could find a way to create immunity from HIV, it would die out.

      Most of the treatments for HIV simply extend the person's life, probably with the hope that they live long enough to find a cure. The drugs are not pleasant, and often make the person ill while trying to swallow them.

      I too am too young to really appreciate not having to worry about Small Pox. I'm not even sure I was given the shot, as I was born after it was declared eradicated (1979).

      --
      ---You're all I need, When the water runs deep, You're all I need, Now I cry my soul to sleep -- Collective Soul, Needs
    3. Re:Small pox? by Reverend528 · · Score: 2, Insightful

      Also, back in the late 1700s, someone couldn't patent a scab off of a cows back.
      Plus you could test treatments on orphans without the risk of being sued.
    4. Re:Small pox? by Chancey · · Score: 2, Informative

      Unfortunately this does not parallel the smallpox eradication... smallpox was a very unique case as far as human diseases go. First, smallpox was eradicated through the use of vaccines (first produced over 200 years ago), which require only one exposure to prevent a person from getting infected. There were also numerous efforts to eradicate smallpox spanning almost 150 years, and culminating in the massive, coordinated effort from the WHO (World Health Organization, not the band) to eliminate smallpox from Africa and India in the 60s-70s.

      To similarly eliminate HIV we would either need a similar vaccine, or to force every single HIV patient in the world (estimated 33-46 million) to adhere to a complicated anti-retroviral therapy for the remainder of their lives.

      The situation for HIV better parallels tuberculosis, which can be effectively cured by common (and relatively inexpensive) antibiotics, but remains prevalent because the treatment regimen is quite long and requires strict patient compliance.

      Also, since smallpox was eradicated by a very well studied vaccine, there was no patent holder to collect royalties...

    5. Re:Small pox? by stonecypher · · Score: 4, Informative

      Wow. So much misinformation in one post.

      How can someone think a rate is 20-60%? That's one to three out of five. It doesn't make any sense. Of course, the source you cite is Wikipedia, which you should know better than, except of course that it says 30-35%, not 20-60% like you claim; at that point it's probably more of a question of measurement differences or other fundamental quality of standard measurements between sample populations.

      Smallpox was still active in the 1960s; why you think it was "eradicated in an effort that spanned the 19th and 20th centuries" is beyond me. Maybe you're misreading the "after successful vaccination campaigns" bit in the wikipedia article; this is one of many reasons why reading an encyclopedia article does not match actual knowledge, since what they're talking about are local, single-city eradications. The actual global eradication effort was begun in the early 1950s by PAHO, which Wikipedia incorrectly cites as 1950 (it started in 1952.) The bulk of Smallpox was driven out of the states around the turn of this century, but the last known US case of non-weaponized Smallpox outbreak was in New York State in 1947, and there were isolated rural cases as late as 1965. The actual eradication wasn't certified by WHO until 1980; cases were found in nature in southern Africa until 1977.

      Incidentally, HIV, like Vareola, doesn't have a mortality rate; it's syndromes like AIDS and Smallpox, not diseases like HIV and Vareola, which have mortality rates. If you understood disease you'd know this. Many people with HIV never develop AIDS at all, and live healthy lives until they die from a car accident or cancer or a bolt of lightning or bad heroin or getting mugged. Now, mortality rates aren't just percentages; they're rates. That's why the correct way to say it is "Smallpox has a thirty eight percent chance of mortality per week." This makes a big difference, but what makes a bigger difference is that AIDS itself doesn't actually cause death. Associated infection does. The AIDS mortality rate is ZERO.

      Why does that matter? Because when you start knowing what you're talking about, you find out that the AIDS associated disease mortality rate is widely different between economic, ethnic and social groups. Why? Because that's not one hundred percent either. Hell, there are two known people who have sero-converted so far (meaning their immune system fought back and won, and they're not even carriers anymore.) We have no idea how they did it, but they did. About five percent of people with HIV do not develop AIDS by the twenty year mark, and show no symptoms whatsoever. The median time between infection and symptoms even displaying is now over ten years. There are known human mutations that create HIV resistance, such as CCR5 delta 32.

      You're just rambling about shit you heard. Get off the soapbox. You're full of crap. No disease has a 100 percent mortality rate over any time frame. You're not even measuring using the right kind of units. The AIDS associated opportunistic infection mortality rate in the United States has been 2.21 per 100 per year since 1998, as accepted by the AMA, the WHO and the CDC.

      Two point two percent per year. One hundred? Go read a book, kid, you're lying through your teeth.

      --
      StoneCypher is Full of BS
  11. By what means are they non-infectious? by r_jensen11 · · Score: 2, Insightful

    Is it just sexually? What about blood transfusions? What about sharing needles?

    AIDS is spreading rapidly in different parts of the world by different means. In Africa and India/Asia, it's spreading because of unprotected sex. In eastern Europe and Russia, it's being spread predominately from dirty needles used for drugs.

  12. Re:Your best bet... by TehDuffman · · Score: 5, Insightful

    Is abstinence really that difficult? Yes
  13. Re:Your best bet... by PrescriptionWarning · · Score: 2, Insightful

    well its obviously not currently working, so i think thats why they're still trying to find a cure/preventative.

  14. Re:AIDs is still a possible species killer. by Anonymous Coward · · Score: 2, Interesting

    Probably not, barring some kind of major mutation. 1. It's hard to transmit, requiring sexual or blood contact. A significant portion, maybe even a majority, of the American population for example is in monogamous relationships and doesn't do drugs. 2. Its slow to spread. Before you get AIDS, you get HIV, and sometimes HIV never really develops into AIDS, other times it takes decades. In either case the specimen has ample time to reproduce. Even if HIV mutates to overcome both of those things, in the long term it would kill off huge segments of the species where it can easily take hold, it is extremely likely some part of the species will be able to resist it. Now would that be you or me? Different question...

  15. Re:Your best bet... by vertinox · · Score: 3, Insightful

    Is abstinence really that difficult?

    You want the average human to stop doing what evolution has spent 300 million years programming them to do? Its kind of like asking bears to not eat trout. Its what they do!

    --
    "I am the king of the Romans, and am superior to rules of grammar!"
    -Sigismund, Holy Roman Emperor (1368-1437)
  16. Re:Your best bet... by gad_zuki! · · Score: 4, Interesting

    >You want the average human to stop doing what evolution has spent 300 million years programming them to do?

    Really? Evolution has been progrmaming people to kill their mates through disease? Whoa, I've missed a lot in sex ed!

    I love how only the most base animal desires get propped out by evolution. I love how people just never say "Hey evolution has instilled logic and compassion into humans." Or "Evolution has instilled moral action" Or "Evolution has instilled guilt and conscious thought." Instead its always fuck and kill, and if you think thats all evolution can do then youre sorely mistaken.

    The real question is the ease of being able to control one's sexual desires vs the the control compassion and empathy have on us. Considering your comment could be (and has) been used to justify everything from rape to office sexual harassment, its interesting how society hasnt given up on some basic moral structures. Evolution again! Tricky aint it?

  17. Drug addicts less significant in Switzerland by DrYak · · Score: 2, Informative

    They only talk about sex.
    Because in Switzerland, that's the main mode of transmission by which people may catch AIDS.

    How about drug addicts and dirty needles?
    There have been extensive efforts against dirty needles. Drug addicts can easily have access to "Kits" that contain proper sterile equipment (syringes, spoons, citrate, alcohol to clean the injection site, etc). They can either buy it cheaply from pharmacies or receive it for free from some organisation. Such efforts have drastically reduced the occurrence of syringe sharing and help drop the HIV transmission rates.
    I think TFA concentrates on sexual transmission because dirty needles have really become rarer in Switzerland, and thus play a less significant role in the AIDS transmission compared to before the introduction of these efforts (or compared to other countries where such efforts don't exist).
    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
  18. Breaking news! by TurinPT · · Score: 5, Funny

    Scientists come up with a device to make HIV patients non-infections.
    This scientific breakthrough will bring hope to millions of people infected with the virus.
    Sources indicate it will be named 'condom'.

    1. Re:Breaking news! by rjhubs · · Score: 2, Informative

      condoms break.

    2. Re:Breaking news! by madbrain · · Score: 2, Informative

      Why was this moderated troll ? Just because the moderator doesn't have sex often enough to have statistically experienced or witnessed this ? Oh, I forgot this is slashdot.

      Newsflash, condoms do break occasionally. They also slip.
      The below study shows a 2% rate of failure per condom, and 2.7% per person.
      http://www.ncbi.nlm.nih.gov/pubmed/8070546

      --
      -- Julien Pierre http://www.madbrain.com/blog
  19. Re:Your best bet... by syousef · · Score: 2

    Is abstinence really that difficult?

    Historically it has certainly proven to be. Not everyone on this planet is educated, has enough wealth that prostitution isn't tempting, or even is in a position to say no if they wish to. You're not talking about the abstinence of a few wealthy individuals but of everyone on the planet infected with an STD.

    --
    These posts express my own personal views, not those of my employer
  20. Yes... by msauve · · Score: 4, Insightful

    the CDC.

    --
    "National Security is the chief cause of national insecurity." - Celine's First Law
  21. Already a way to make non-infectious by Lunzo · · Score: 2, Informative

    It's cheap, small, easily mass-produced, easy to use, 100% effective... It's called a CONDOM.

    How I wish the various religious groups and governments would endorse proper sex education and provision of a plentiful supply of condoms, instead of pushing the abstinence only bulls---, which has completely failed.

  22. It is a risky statement. by jd · · Score: 2, Interesting
    HIV mutates fast and confusingly. De-activated HIV, for the purpose of creating a vaccine, can - and has - reactivated itself. HIV is not always immediately detectable - many methods use detection of antibodies, so those with a damaged immune system may carry the virus and be considered negative with such tests. This may have happened with a group of women in Africa who appeared to be immune to the virus (they remained negative, despite repeated exposure to the virus) but then some of them started dying from the full-blown form suddenly. None of the usual intermediate stages. My guess is that they still test negative, though, using the test they've been using so far.

    So, even if they are 100% absolutely right for the samples they have, at the time the experiment was conducted, that confidence must fall as you increase the range of HIV viruses and the range of time they have to mutate.

    You must also consider that we're on some Nth generation of anti-virals because AIDS has mutated to develop resistance to all of the others. The second that happens with the current generation is the second the risk goes from near-zero to infinity, and nobody knows for sure when that moment will be. Hence the use of all kinds of toxic substances and anti-virals mixed together, so that immunity from one won't help, so minimizing the risk of mutant strains surviving. But you know that they will, sooner or later, and that when they do, they will spread. It might be tomorrow, but I'm guessing it's actually not too likely this side of 2020.

    Of course, if everyone considers it safe, and takes no precautions, I imagine the probability of such a mutation surviving and spreading will go up. As such, even if it is "safe" for the moment, it can't be safe forever and when it does develop resistance, it may take years - or decades - for the resistant strain to even get detected.

    --
    It's a small world and it smells funny; I'd buy another if it wasn't for the money; Take back what I paid (SoM)
  23. You ARE kidding, right? by NIckGorton · · Score: 4, Interesting

    For every one antibiotic rx I write for an illness that probably doesn't need it (generally because I am a wimp) I have to convince another ten people who are certain that they need antibiotics... that they don't.

    Generally the reason most physicians prescribe inappropriately is because asshats like Mr "I have not had a doctor do, or say anything to me that I did not already know since I was about 10" know better that they absolutely do need antibiotics (when they obviously don't). It takes thirty seconds to write the prescription and sometimes thirty minutes to escape the asshat.

    I actually had a complaint letter written to the CEO of the hospital where I worked a few years back from a parent who brought their child into the ER with what was obviously a viral syndrome. Their letter literally said I brought my child to the ER to get a prescription for antibiotics, not to be told that he didn't need antibiotics. And I get several complaints yearly from irate people who didn't like my answer that they didn't need antibiotics. I've never gotten a complaint when I prescribed them.

    So you can't have it both ways. If you want a doctor who has real clinical acumen, you can't also have him be a prescription vending machine.

    1. Re:You ARE kidding, right? by MachineShedFred · · Score: 2, Insightful

      And this is yet another reason that people don't trust doctors. Instead of seeing a person as a patient, and quite frankly, the single most experienced person with their body, you see an "asshat".


      I'm afraid that the terms "patient" and "asshat" are not mutually exclusive. Especially in your case.

      You had some bad experiences with some doctors. Congratulations. Does this mean that every doctor everywhere is as outrageously incompetent as you seem to think they are? This DOCTOR just told you why doctors won't just whip out the Rx pad and write up a script for any old thing the patient wants, and you're arguing that he should just prescribe the wrong treatment for what the patient has.

      Did it ever occur to you that you JUST might have been the exception to the rule, and that most people don't know jack shit about what's going on with their body, THUS THE VISIT TO THE DOCTOR?
      --
      Slashdot still doesnâ(TM)t support Unicode after it was added to the HTML standard in 1997.
  24. So who wants to... by Crazy+Taco · · Score: 2, Insightful

    So who wants to be the one to test this hypothesis?

    On another note, how can you say for sure if this even works? Usually whenever an AIDS vaccine is tried in humans, it is given to a population of people at high risk of getting HIV(usually gay men). How can you tell if something like this stops people from spreading it, when their partners are interacting with other, infectious people? They are likely to get HIV regardless, if not from the non-infectious person, then from someone else. How do you figure out which partner gave who what?

    --
    Beware of bugs in the above code; I have only proved it correct, not tried it.