Many Scientists Using Performance Enhancing Drugs
docinthemachine is one of several readers to send word of a new poll published in Nature showing unprecedented levels of cognitive performance-enhancing drug abuse by top academic scientists. The poll, conducted among subscribers to Nature, surveyed 1,400 scientists from 60 nations (70% from the US). 20% reported using performance-enhancing drugs. Among the drug-using population, 62% used Ritalin, 44% used Provigil, and 15% used beta-blockers like Inderal. Frequency of use was evenly divided among those who used drugs daily, weekly, monthly, and once a year. All such use without a prescription is illegal.
It is "drug abuse" when drugs are used without the informed consent of an individual; it is simply "illegal drug use" (and very likely legislative abuse of personal liberties at the same time) when an adult makes an informed choice about drug use that doesn't comply with the current law.
People need to move away from the mindset where media pompously and wrongly attributes polar positions such as "right and wrong" and "use and abuse" to be a 100% lexical replacement for "legal and illegal." Anyone with any sense at all knows better than that. A significant number of the laws on the books in the country I live in (the USA) are inherently wrong, outright un- or anti-constitutional, or something even worse. Using them to define what is "right" leads directly to behaviors that are despicable — or worse.
One can be cynical and simply say that this is because our legislators aren't very good at their jobs. Both from the standpoint of making good law in the first place, and also in the sense that they seem to be almost incapable of admitting they made a mistake and taking bad law off the books. Personally, I think it's because they're not very good at liberty — and very good indeed at lawmaking.
There's an old saw that goes, "never attribute to malice what can be explained by incompetence", but I think in the case of bad law, we are indeed looking at malice aforethought. It seems to me that these people have agendas that can only be construed to be "for the people" if you slept through history class and have never read any of the founding documents with any interest. Like most Americans. :(
I've fallen off your lawn, and I can't get up.
We prescribe these drugs to millions of kids who most likely have nothing "wrong" with them, and people have a problem when some adults do the same thing?
This isn't athletics. The point isn't fairness. The point is advancing the science. I have serious doubts that these drugs are actually helping anybody do research who didn't already have some kind of problem, but it's none of our damn business, either.
Caffeine anyone?
Strangely absent from the list. I've known few scientists that didn't consume lots of caffeine.
Give me Classic Slashdot or give me death!
The blurb makes it sound as if all this use is illegal. I would imagine most isn't: most of these people will have prescriptions but are using them for off-label purposes. Which is legal.
So, will they take away your Nobel if you've been found to use science-enhancing drugs?
It isn't necessarily illegal to possess or use prescription medicine without a prescription unless it is a controlled substance or there are state or other laws that come into play. It is illegal to dispense it without a presecription.
Inderal is not a controlled substance.
Just because it CAN be done, doesn't mean it should!
Most beta blockers are used as a treatment for high blood pressure. Surely the stress levels that these scientists experience would justify that kind of prescription.
The simple truth is that interstellar distances will not fit into the human imagination
- Douglas Adams
By this strange scrawney man with black rimmed glases in a tan trenchcoat wearing sneakers and waving around a metal tool with a blue glowing end.
The man was apparently muttering about some kind of oil that supposedly made the brain work faster or some such nonsense.
His accomplices included a blonde bimbo, a middle aged woman resembling a sturng out housewife, her young ethnic lover, and a poorly put together RC dog.
Tsukasa: All I really want, is to be left alone...
Performance enhancing means Viagra.... no wonder kids aren't doing science.
An Eye for an Eye will make the whole world blind - Gandhi
Does this mean there will be mandatory drug testing at the Science Olympiad?
:^p
Just what was in Albert Einstein's pipe?
And how did Stephen Hawking really end up in that wheelchair?
My confidence is shattered.
-- Insert witty one-liner here. --
Actually, lots of people use beta-blockers as a performance enhancer. The most common use is for musicians who have to do an audition. Beta-blockers really reduce any shakes that may ruin a performance.
I had a prescription for years to treat familial tremors. The drug worked well but tended to make me drowsy so I quit. As I get older, the shakes get worse and I may have to go back on them. C'est la vie. (shrugs)
You say those without a prescription are doing it illegally. Well, how many are legally taking these medications as prescribed by a physician?
Inderal is a cheap beta blocker ($4 for a month's supply) commonly used for the treatment of hypertension and various heart diseases. It can also be used on an as-needed basis for stage fright.
Adult ADHD may be treated with Ritalin. If people are prescribed these medicines, then no foul.
Help! I'm a slashdot refugee.
I use Adderall damn that drug is addictive. I can stay up all night then take that and I feel good as new an hour later. Plus it has the benefit for me of allowing me to concentrate better and get more work done. It also stops me from clicking the damn stumbleupon button for hours on end. With it I get twice as much work done and can think twice as well.
Please note I do have a prescription for it and I dont even need to fake ADD to get it, just he gives me a slightly higher dose than I might need.
In today's news, Berry Dexter Bonds was informed that his three Nobel prizes for curing cancer and inventing a practical flying car will be revoked. Drug testing revealed that banned brain-enhancing substances were in his bloodstream just prior the prize ceremony. Testing has been standard procedure for the Nobel ceremonies since it was discovered that the inventor of the brain-enhancing drug, IQtrophine, used it to win a Nobel prize for curing the common cold.
It has also been revealed that Steven Nash of the Phoenix Suns NBA team has been taking brain enhancing drugs to help him make smarter, more accurate ball passes. One side effect is that it stunted his growth. College photos revealed that he used to be taller than Shaquille O'Neal. "I wasn't making it as a center, so I decided to become the Mother of All Point Guards", he said at a news conference.
Table-ized A.I.
But then again, life's not fair.
So if life's not fair, why ban "cheating" with drugs? Cheating is part of being unfair.
If I have been able to see further than others, it is because I bought a pair of binoculars.
I mean, if you learned something from a professor who was under the influence of performance enhancing drugs, do you have to forget it?
Give a man a fish and you have fed him for today. Teach a man to fish, and he'll say "WHERE'S MY FISH, YOU IDIOT?"
I admire your romanticism, but science isn't sport. It's not about a fair fight between equals. Science is about using any method you can to explain or measure a detail of the universe that nobody else can. So long as you do it yourself (i.e. you didn't actually steal someone else's idea or result), anything goes. There is no Nobel prize for featherweight science. Either you're the best, or you're not - and your funding will reflect this.
It is by will alone I set my mind in motion...
Also, where do you draw the line between drugs and things like proper nutrition?
By consuming an optimal diet of the proper nutrients (which are just specific chemical compounds) am I really a lesser person because I did not make my achievements while on a near starvation diet?
Am I cheating by juicing up more vegetables than I could eat whole and obtaining all those extra nutrients?
_You_ can drink drugs are "self-defeating".. But who cares? If I used drugs to save my life, then I would say that is good. I won't even stop to think about how I have degraded myself by staying alive. I don't think any cancer survivors feel any smaller because they needed to use drugs to beat cancer..
If I use drugs to clear my head to solve an important problem, then I don't consider that problem any less solved. I'm not working on solving a problem just to see if I can do it... I want to save the world for the world's sake, not my sake.
I would say that this line of thinking is kind of "selfish" in a way. The need for people to believe sports are fair and uncompromised by drugs has skewed the way people think of performance enhancment. Enhancement is good. We like enhancement. Get over it.
"They that give up essential liberty to obtain a little temporary safety deserve neither liberty nor safety"-B.Franklin
I know at my University for example that there is widespread use of Ritalin for studying purposes once it got out that you can learn entire courses inside and out pulling all-nighters when you're on Ritalin.
A friend of mine is a regular user of Ritalin, and because I knew the guy (and his marks) before he started using I can tell you with some confidence that Ritalin will add a very significant boost to your GPA.
I also have anecdotal evidence of many pre-med students using Ritalin when they study for the MCAT, prerequisite courses, etc. since competition for med school here is so fierce.
If the students are doing it because they're under pressure for higher grades, why wouldn't the professors and scientists be doing it when they're under (arguably greater) pressure to produce research results.
Ritalin is scary stuff. There are no good-quality long-term studies on the effects of Ritalin. And there is some evidence that ritalin is carcinogenic and can cause permanent changes in the brain. There is a partial summary of potential problems with ritalin here (mostly as it is used to treat ADHD).
I think that is best single argument I have ever heard against state interference in people's behaviour (aka. the 'nanny state'). Interesting, thanks.
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One person achieving without enhancing therapies what someone else needs enhancing therapies to achieve does not lessen the achievement of either party.
All it means is that twice as many people are capable of achieving the same goal. In this case, it's performing highly complex and detailed scientific analysis.
Isn't that a good thing?
Finally had enough. Come see us over at https://soylentnews.org/
The poll defines "top academic scientist" as a reader of Nature. Obviously this has major issues. For one, very few serious scientists read Nature regularly, since it doesn't speak directly to a given field. In my "top academic" institution, almost all of the people I know who have gone to Nature's website recently are either science undergrads doing low level research for a simple presentation or non-scientists trying to figure out what was meant by article X which they saw referenced in an AP news story. In fact, the poll itself wouldn't be encountered by most scientists looking at Nature, since scientists are almost always entering through an external search portal directly to an article of interest. Scientists with real pressure (say, busy grad students or professors) don't browse Nature. They strategically read an occasional article in Nature, but in most cases the same research will have been published already in greater detail in a more field-specific journal.
Collectively, all of this means that Nature's pool of respondents was almost certainly not "top scientists." Instead, they were selecting undergrads, non-scientists, and generally people with a lot of extra time on their hands. Yes, we know undergrads use Ritalin to cheat on tests. We have no indication, however, that Ritalin helps one to do the deep creative thinking necessary for involved science.
"I zero-index my hamsters" - Willtor (147206)
Even if you say that, when they get an emergency patient, they're much too busy saving that person's life to investigate whether it's all their fault and they should be left to die.
Honestly, I still prefer it that way.
Right. Carry on. Glad that's sorted. =)
He's getting rather old, but he's a good mouse.
I appreciate /. linking to my post on this topic- I wanted to a share some further details of the drugs. I predict the potential for use/abuse of these agents to be unprecedented.
The primary agents to hit the streets are eugaroics. They are a class of novel stimulants that produce long-lasting mental arousal. They are unique in producing hypervigilence and alertness without peripheral effects or addidition of usual stimulants. Strangely, they have minimal effect on sleep structure, and do not cause rebound hypersomnolence (crashing).
You might also be interested in Ampakines are similar but also cause memory enhancement (just a bit of abuse potential there). One of these - a drug code-named CX717 from Cortex - reportedly enabled sleep deprived rhesus monkeys to outperform rested normal monkeys on memory tasks.
all the juicy details are here:
http://docinthemachine.com/2007/03/09/eugeroic/ and
http://docinthemachine.com/2008/02/12/enhanceperformance/
the biggest issue here is how far would you go to enhance your body's performance if risks were minimal? Would you take a drug, implant a bionic retina? or replace your limbs with bionic ones. Discussions I have had with those on the international olympic committee and DARPA indicate many many people will go the route of biomodification. A discussion of this concept is here:
http://docinthemachine.com/2007/01/22/cateye/
I also use Provigil, but because I have sleep apnea.. Even WITH my mask and CPAP, I have huge sleep disruptions. The Dr's suggested surgery, but admitted that it may not provide much relief and I may
:)
actually still need the CPAP... Therefore, I use the CPAP as much as I can, and pop the Provigil on
the days when I can tell I didn't get any sleep. My only side effect that I've found is talking. Once
I pop a Provigil, about 1/2 hour later, I can't shutup. I will just rattle on and on... And for the
folks at work, they knew right away that something was wrong till I explained why I had to take it.
As for brain enhancement, etc... Naw... Just makes you awake. Though I'll be the first to admit that
it is rather distracting to fall asleep while your trying to think of something.
BTW, For those planning on using this as a reason to get Provigil, you have to have REAL evidence of a
problem. I had a RUDE AWAKENING when I bumped into another vehicle at a stop light. I fell asleep
at the wheel waiting for it to turn green. Luckily nobody was hurt, and it made me drop the excuses as
to why I was tired at work.
--- Relax, that mass muderer is just trying to reduce our carbon footprint, one fetus at a time...
Who makes that judgment? Is it the EMT responding on the scene? Is the the ambulance driver? Does the doctor decide when you are on the operating table?
You are going to ask people whose profession is to help fix people and save lives to determine who is worthy of being saved, and who isn't? This is the horribly unethical problem that is the notion of being "uninsured" in the first place. You want to compound that with subjective life style judgments?
So, a gay person with AIDS is treated by a fundamentalist doctor who believes sexuality is a lifestyle choice, and thus, AIDS treatment costs are an unnecessary burden on the tax payer. This is truly the extreme of what the US already has in place with HMOs who are constantly crunching numbers, as opposed to doing everything in their power to help people get better.
Sure, what you say is a wonderful idea. Freedom of choice, my body, and all that. But this thing is called society for a reason. If you really want to destroy yourself, do it outside the realm of society. But of course, these junkies don't hold such noble notions of personal responsibility, so you can't expect them (nor society) to act in accord with such notions.
Way to miss the gp's point entirely. He wasn't arguing science isn't done that way, he's arguing you will have no respect for yourself if you do science that way. And if you do science that way and still respect yourself, you have deeper issues than respect dogging you.
Gerry
EMTALA is an unfunded mandate that says that the nurses who work in an ER, the hospital who runs the ER, and ER physicians like me have to pay for uninsured emergency care. It takes a segment of the US economy and says we have to take responsibility for and subsidize what everyone else doesn't. That cheap McDonalds hamburger you ate today that is less expensive because McDonalds doesn't offer health insurance? I paid for a part of that.
Of course I am thankful for EMTALA every time that I use it to force a surgeon to take the appendix out of an uninsured teenager. I also feel that I am paid quite well enough even though about 30% of the ER care and 50% of the overall care I provide is uncompensated (I volunteer two days a week at a low income clinic that sees a lot of uninsured patients so that bumps the % up.) However overall I hate EMTALA precisely because its used as a crutch: I'm sure Bush slept very well at night after vetoing SCHIP because he thinks that every American gets health care since even if we are uninsured we can go to the ER (where most of the care people need - like prevention and treatment of chronic disease can't be done).
Can you stamp an asterisk on a Nobel Prize?
I have no clue how to go doctor shopping; I come by my drugs the hard way (ie, having problems that really screw up my life if I'm not on them).
Of course, my personal sense of ethics says these drugs should be available to anyone making an informed choice. At least some doctors are willing to prescribe low doses to people they feel are responsible and would be helped by them. If you're intending to use them non-recreationally (ie, to help with focus) you may well qualify. So seriously, if you and your doctor have a good relationship, just... ask. Tell them you have difficulty focusing sometimes (or whatever the case is) and were wondering if some sort of stimulant might help. Don't lie to them, or exagerrate symptoms. There's quite possibly no need, and it probably won't work (not to mention being illegal and imo unethical).
In short, if you want to convince a physician that CNS stimulants would enhance your quality of life... then tell them so :) Say why you think that's true, and approach the issue as asking your doctor for help, not trying to con them out of drugs.
There are a variety of drug options, as well as non-drug options (various techniques for focusing, etc -- they actually do work, and they work in concert with the drugs as well). You'll want to get detailed input from someone who knows the drugs better than you or I, so give them all the info they need and give them correct info.
So if someone uses drugs and contracts a communicable disease as a result, you would not have society treat them, and let them continue to spread the disease until someone catches it who can't be blamed for taking unnecessary risks? Do you see the problem here? It is in society's best interest to address the health problems of individuals even if they got those problems through objectionable behavior. You can address the behavior in other ways, but trying to punish individuals by not taking care of the sick actually punishes the whole society. You're asking society to pay a bigger price in the long run just so you can feel good about having taken a punitive (and, as you yourself acknowledge, somewhat mean-spirited) stance.
I remember that Bob Wallace (ninth Microsoft employee) posted in alt.drugs.psychedelics years ago that Microsoft experimented with I believe 2C-* phenethylamines as enhancers for creativity and concentration for programming. Unfortunately most of his posts got deleted from the google groups archive after or shortly before his untimely death a few years ago. I did copy most of his posts before they went offline, but they are on some lost harddisk/zipdrive somewhere... which would take longer to find then this topic will stay alive and read on slashdot.
That's the best analogy for the issue I've seen so far. Do we want our scientists to be human beings or Guild Navigator-esque mutants who interact little with normal society?
I have 2 comments, but I didn't read all of the 600 comments, so I apologize if I duplicate another's thoughts.
1) What kind of response bias is there in this? They survey Nature's readers, but is the 1400 the number of responses? If so, perhaps people with a history of use or knowing someone who used an enhancing substance responded preferentially. Maybe someone needs to be on a performance enhancing drug to even subscribe with institutional subscriptions now-a-days.
2) Beta-blockers like propranolol [trade name-Inderal] can be used for anxiety, hypertension, tachycardia, etc. I've never heard them described as drugs of abuse or performance enhancing drugs, save perhaps for someone doing public speaking. In fact, beta-blockers are given to drug addicts/alcoholics for the treatment of anxiety instead of Xanax or other benzodiazepines. I tried to find a the statistics on Beta-blocker prescription numbers, but could only find that there were >$3 billion in sales for beta blockers within the last few years (It was like looking for a needle in a Viagra-stack). I have to wonder, what is the baseline rate of beta-blocker usage that is not performance-enhancing in a group of people that may be type-A personalities, have high stress jobs if they are writing grants with 8-9% funding success rates, and may be of an older age bracket if they are personal vs institutional subscribers and also have the time and interest in replying to an unsolicited survey?
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