Diet of Fast Food and Candy May Cause Alzheimer's
lurking_giant sends along a Reuters report on research out of Sweden indicating that a diet rich in fat, sugar, and cholesterol could increase the risk of Alzheimer's, at least in mice. "'On examining the brains of these mice, we found a chemical change not unlike that found in the Alzheimer brain,' [said] Susanne Akterin, a researcher at the Karolinska Institutet's Alzheimer's Disease Research Center... 'We now suspect that a high intake of fat and cholesterol in combination with genetic factors... can adversely affect several brain substances, which can be a contributory factor in the development of Alzheimer's.' ... These mice showed chemical changes in their brains, indicating an abnormal build-up of the protein tau as well as signs that cholesterol in food reduced levels of another protein called Arc involved in memory storage."
I'm not surprised that generally mismanaging your body with bad nutrition would make it more likely to get some kind of degenerative disease... While it's nice to find hard evidence I think at least the geek population would be plain dumb so assume otherwise.
Now if we could only get governments to have some kind of taxes on the bad stuff, and subsidize the good stuff. I'd eat better if I could afford it, quite frankly.
.: Max Romantschuk
I know, I know, we need these studies, but duh.
That's an ancient cliche but very relevant. Eating too much rock dust would cause cancer. So too would anything else consumed in a quantity that creates an imbalance.
All this leftover halloween candy... Well... I guess I'm screwed then.
About what?... I forget
Sounds like absolute hogwash to me. Now I have to head for the candy machine and get me one of those ... you know ... what are they called? ... things.
You can't see ANYTHING from a car, You've got to get out of the goddamned contraption and walk...Edward Abbey
"We now suspect that"
Yeah...I also can suspect that a giant skids are aliens incarnations from Frodo...
The world is already full of FUD, comeback with real prof please.
Math is beautiful... e^(pi*i)+1=0
. . . fed on a diet of nicotine and alcohol, behaved in a way described by Dr. Akterin as "ladish", and taunted her with "tits out for the mice!"
Schroedinger's Brexit: The UK is both in and out of the EU at the same time!
Living will kill you.
I'm eating a Twinkie
I'm sick of all the vague and useless FUD coming out of the scientific community. There is not a single thing that they can discover or will discover that will change the fact that we will die.
Regardless of the novel intent, the underlying message, that we should be in constant fear, of what we eat, breath, and drink is really no improvement of where we were 200 years ago, before there were even scientists. What's the point! Get back to work on flying cars leave the mice alone.
I can hear already the trumpets of safety wailing away. Soon we'll have even more legislation about the sorts of food that we can eat, supposedly in our best interest, but really, a puritanical expression of clinging to life at every last grasp no matter what. We should only be puritans about things that matter.
Sometimes life is worth more than just extending it. Sometimes there is a choice between living free and well versus merely living longer.
This is my sig.
After years of telling people to avoid eggs suddenly it turns out that they're not bad for you after all. It's partly the media and partly scientists who want the limelight provided by the media, but it's really irresponsible how lifestyle changes are suggested (and in some cases demanded) based on one or two studies like this, while centuries of anecdotal evidence to the contrary are ignored.
Brackets contain world's first nanosig, highly magnified:[.]
... would suggest that it does not much good if you behave in an unbalanced manner, irrespective of the domain. If you are not balanced, you end up flat on your face, as easy as that (admittedly, it is quite hard to rediscover common sense after a treat of 'scientific values clarification').
CC.
TaijiQuan (Huang, 5 loosenings)
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So go jump in front of a bus, we will thank you later for making our day.
If this makes you so "sick", stop reading it! Study after study has shown, with scientific accuracy, that reading stuff that makes you sick (tada) MAKES YOU SICK !! So STOP READING STUFF THAT MAKES YOU SICK!
Carry on
Damn, that explains Alzheimer's and cancer and diabetes and stuff over a hundred years ago; it was all the Big Macs and pizza slices and sodas... Oh, WAIT. They didn't have that stuff a hundred years ago. Wow, maybe the Government needs to fund a study on what caused say, Alzheimer's, one hundred years ago if it wasn't a Big Mac.
Sounds like Alzheimer's is going to become the "new cancer" where everything causes Alzheimer's. Can we just fastforward to the part where they admit they don't have a clue what causes it, please?
Ever also thought about a relation of food and pharma industry?
The United States has a Food and Drug Administration. Think about it.
Before anybody runs to diet products because they shouldn't have sugar: There's plenty of anecdotal evidence...
Peter predicted that you would "deliberately forget" creation 2000 years ago...
The title states that a "Diet of Fast Food and Candy May Cause Alzheimers" and the link states that "diet rich in fat, sugar, and cholesterol could increase the risk of Alzheimer's".
Yet in the body of the article we get this little gem: "We now suspect that a high intake of fat and cholesterol in combination with genetic factors ... can adversely affect several brain substances...".
Seems they conveniently left out sugar in the summary.
Interesting
The Tao that can be spoken is not the one eternal Tao
a Reuters report on research out of Sweden indicating that a diet rich in fat, sugar, and cholesterol could increase the risk of Alzheimer's, at least in mice.
The poster neglected to link to the pic of the test subject.
== Jez ==
Do you miss Firefox? Try Pale Moon.
The point here is that the study said nothing that was new or useful. What we have hear is some broad tortured a mouse and said that we need to eat more healthily. Like, what did she really do that was useful? Nothing. There's no guarantee that if you follow her conclusion, you won't get alzheimers. There's nothing to treat people that already have gotten it. There's nothing but a bunch of dead mice, a scientist with a flair for self promotion, saying that we need to eat better. Big deal.
This is my sig.
I thought the mice were experimenting on us?
</hhgttg>
I forgot to order a pizza!
May Peace Prevail On Earth
The study is quite flawed, she might as well feed them a diet "rich in rat poison" and conclude that it's quite fatal for the critters.
There are more studies needed, focusing on the separate compounds; is a diet rich in sugar bad? Is the sugar rich diet bad if the net caloric intake is low? Is the sugar rich diets bad when combined with nutritional supplements that cover the nutritional needs that sugar doesn't provide? Is a combination diet of sugar and fat worse or better than the single sugar or single fat ones? Is HDL cholesterol a equal factor as LDL cholesterol? In what manners do the mice metabolism change in the diets? Could these changes perhaps be blocked by medication, and if yes, will it prevent alzheimers?
The study tells us what we already know, a diet of junk food is bad for you. However, most likely a diet of junk food will kill you trough some other pathway before you develop alzheimers.
As you'll find with almost all dietary research, the conclusions are baseless. They fed the mice junk food, and focused on only a couple measures of the contents of the junk food - "fat", cholesterol, sugar. What about the other crap in junk food? What about the nutrients you DON'T find in junk food but that are crucial to life? Do any of those components (or lack thereof) correlate better? Blank out. What types of fat are bad, and what types are good? Trans fat? polyunsaturated? monounsaturated? saturated? long chain, medium chain, or short chain? WHICH TYPES OF FAT?! Blank out.
Nope, you won't find that here. All fat is assumed to be bad. Other studies show all cholesterol to be bad, or all protein to be bad, or all carbs to be bad, without actually examining in detail the nutrient content of the food to find what component actually correlates the most with their definition of "bad".
Until a randomized, double blind study is done, the only thing you can conclude from this is that junk food correlates to a certain degree with Alzheimer's. Nothing can be said about "fat", nor about cholesterol, nor about sugar.
The article points out, they were fed "fast food", which contains things other than fat and cholesterol. Fast food is also cooked differently than other foods. Just blindly saying "fast food" was the cause is misleading at best. It is a known fact that fast food contains chemicals not normally found in other foods. It is also a known fact that how food is cooked can change it's chemical composition dramatically, making normally healthy food toxic. Just another "study" where there is a poor control group and general assumption of "it's the fat" not taking into account other factors or combination of factors. It's a study which uses only that data they want to prove an EMOTION/POLITICAL MOTIVATION towards fast food in general. It really doesn't find the real cause.
As to the sugar comments, the real problem is not sugar in general. It is corn syrup, a chemically produced/altered sugar. It goes toward my first point. Just because it's similar doesn't make it the same.
We need to get corn syrup, melamine, and all the other nasty chemicals/chemically produced ingredients out of the food supply. "Small quantities" are not safe. We also need to quit using the "food pyramid" originally designed for the proper food intake of cattle not people. We need to quit being "sheeple".
you mean eating junk food is bad for you?
I understand that correlation is not causation. This is an important principle of statistical analysis. Though this principle alone doesn't instantly render the enterprise of statistical data-gathering worthless, does it?
Whenever someone hears a conclusion that disagrees with their pre-existing biases, they say, "well stats can be made to say anything you want." So does that mean that we can never trust any statistical evidence ever, no matter how how rigorously the principles of good data-gathering were applied?
So I ask you, when ARE stats useful?
I for one would like to welcome our new...eh what ...already?
MSG.
Just wondering, who do you think you that you can run around getting government involved in everything? Seriously, tax it? Where did that come from? Because more government is all we need, right? If people want to put crap into their bodies, so be it.
Are you going to tax healthy restaurants too? Which menu items will you tax? I hope you won't tax the Salad+Vinegarett combos. I suppose if you support universal healthcare then you could make a case for taxing unhealthy foods. I love people that think we need the government to baby our citizens into behaving and eating well.
On a side note, I haven't RTA, but my guess is they correlate these two, and do not find the cause.
IANABiologist, but I've read some papers that make a fairly convincing case that Alzheimers is simply diabetes in the brain.
Fast foods (and candy of course) are terribly rich in starch. The starch/sugar-> glucose process takes very little effort on behalf of your body, and is very fast. Result is tons of glucose spikes in your blood, which over time decreases insulin sensitivity of your (muscles, brain). That's not even mentioning the free radicals (cancer agents) released when processing the starches.
So the answer is not a blanket "avoid fast food" (or, heaven forbid tax it) but when you go out to eat, choose what you eat carefully. Stay away from the simple carbs like fries, get proteins and fibers.
We've had Alzheimer's long before we had "fast food".
Apparently you are not old enough to remember the saccharine scare of the 70's. Diet sodas were introduced, containing that chemical. Then, some nanny state idiots came along and said it causes cancer in lab rats or mice. After all the panic, people boycotting diet soda, someone did a little digging into the research. Come to find out that the lab rats were fed the equivalent amount which would require a human to consume 500 or more 12 oz diet sodas a day! Mice do NOT equal humans, as much as researcher would like you to think. If a study of humans, who have alzheimers, finds that their diet was rich in fast food & sugar, then you might have a case. As for getting the government to put a food tax on something, I say NO! The government runs enough of my life now, and in 09 will more than likely be running more of it, so no thank you for a food tax. I find the problem with nutrition in America like this. We eat too many preprocessed foods than we did when I was a kid. Most people "grew their own" food in gardens, which gave us minerals, enzymes, and antibodies that we no longer get now that everything comes prepackaged.
Occam's razor applies to science as well. If you are not doing the simplest possible thing to solve the problem at hand, you are dicking around at humanity's expense. I think this story falls into that category of self indulgence funded by human fear and I think that's terrible.
It's fine for you to wave the flag of basic research, but honestly, I'm questioning whether or not this is in fact the way to go. We've been onto this "basic research" approach for quite some time now and have very little to show for it. I think a Manhattan style approach would be far more efficient.
You could probably cut a lot of crap out with manhattan style project planning for all major dieseases. You go and establish prevention tracking databases as I described, and then open up lines of inquiries as prescribed towards several major approaches towards curing the disease in question. In cancer it might be elevating immune responses, killing the cells, starving the tumors, whatever, and just get those approaches down. If you have to do detailed research there, then obviously do it. You would assign scientists to each slot, and that's what their career is. If they can't get it done, then replace them... and the scientist can either be sent off to work another problem, off to teach, or just sent back to wawa, who cares.
Consider this approach for alzheimers and this article... you could take millions of dollars and pay people to torture mice and find out everything about them, then spend billions more trying out different things in people only to find out that it doesn't work because mice are not human..., or you could set up a data warehouse that tracks what people do.
Just take any number of family members of alzheimers patients, gather up as much data about their diets as possible, and create a public wiki with a data mining engine to let and go -any- researcher mine the stuff for statistical links.
Any sort of dietary culprit would stick out like a red flag and from there you could do genetic testing on the people involved to determine if the diet triggers an alzheimer's gene.
Because self reporting might not be accurate enough, going forward, you could add the support of supermarkets and restaurants to dump their data from participating credit card holders to this database and then you'd -know- exactly what those newer participants ate.
I would think the whole shebang, from soup to nuts, would cost less than a few million bucks to set up and we would be done already. Instead, we got this person waving around basic research, a pile of dead mice, and really nothing useful for it. You can call it science as much as you want, but I call it religion...
If I want a religion, I can pick one a lot more entertaining than some dike stuffing rodents into a torture pit to say that mcdonald's is bad for us. I like an angry judeo-christian god smiting everyone with flood and fire and brimstone, not even for any just reason, but, because, he's just a god and a dick and can do that. Sure, fire and brimstone god isn't going to cure alzheimers with some miracle, but then again, neither is some dike killing mice for the fuck of it.
This is my sig.
By then you will no longer remember what the question was..
FRA: STFU GTFO
Food is an very emotional topic - witness what happens to sales of a product after a scare story
Nutritional studies are oftan exercises in advanced statistics, it can be very hard to remove the effects of other factors
Regarding diets - the ancient greeks got it right - eat in moderation. Having steak every day is a major imbalence, although a nice one (also applies to ice cream etc.)
The food industry will make what sells, they will make low sugar/fat whatever, if enough people buy it. These guys are here to make a profit and will not build a factory to make something that does not sell.
Want to know who is responsible for your diet? Look in the mirror.
Alzheimer's has certain autoimmune-like tendencies. Autoimmune diseases are generally thought to have a genetic and an environmental component: Hashimoto's, for instance, is thought to spring at least in part from overconsumption of iodine (ironic, considering iodine was added to the US food supply to prevent goiter, another thyroid disorder) combined with a genetic predisposition.
With this article in mind, then, it is not ridiculous to think that dietary intake might play a large role in the development of a disorder like Alzheimer's.
At least in America, if medical science can't figure out what causes a medical condition, they blame it on the patient's "bad" behavior.
For example, we were told for years that ulcers were caused by stress so the recommended treatment was to reduce stress. Then one day, oops, it was discovered that the most common cause was Helicobacter Pylori which can be treated with antibiotics.
Fast Food and candy will kill your brain...
...FAST!
Co-operation beats competition
"And this is rodent research, so there is no such thing as a double blind study."
Mister Peabody: "Surely, Neuronaut137, you've heard of the three blind mice."
I love (or rather, *don't* love), how whenever there's a story that might potentially affect the typical slashdot reader's lifestyle, that "correlation does not equal causation" tage pops up. Guess what people - sometimes it does.
But how much will you lose weight using this diet?
Damnit. I meant "because that value goes mostly anti-parallel to the length of the molecules in the food".
Any sufficiently advanced intelligence is indistinguishable from stupidity.
Well, if there's one thing I've learned over the past few years is that the best way to deal with the Tau is by cleansing them via Exterminatus.
Joking aside:
I have a very simple diet that really doesn't involve a lot of cooking (see: none) but I eat a lot of basic fruits/vegetables, meats/cheeses, and things like that. It's not terribly expensive since the foods themselves are all easily purchased in bulk and I eat better and healthier than most everyone else I know. Too often people (especially we proud bachelors) equate eating at home to involve tons of annoying cooking, but it's pretty simple to eat well cheaply.
By keeping lots of simple items about like fruits, cheeses, sandwich style meats, etc. that are healthy but also require 0 preparation it becomes a simple matter to eat well. Even when you go digging for a snack, what you grab will be good for you. Thanks to having easy to eat food at home, you won't sit there going "what will I cook for dinner for myself" and just end up going "ah fuck it I'll go buy a burger." No more fast food = more money in your back pocket, and you'll find yourself feeling a whole lot better in a hurry.
Granted, if you have a family this entire idea goes to crap since it's cheaper to do meals for the whole family, so you'll have to figure that one out for yourself.
That's not even the worst of it! I saw a report this morning that a diet of fast food and candy may cause Alzheimer's.
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http://en.wikipedia.org/wiki/Aspartame_controversy
I drink a ton of diet tea myself, and its all about weighing risks:
1) Eat a bunch of sugar and you get the terrible pains in old age that obesity and diabetes cause.
2) Eat a bunch of vegetables and you get viruses from the water used to irrigate them.
3) Eat a bunch of red meat and maybe get bowel problems.
4) Eat a bunch of chicken and contribute to the destruction of your environment due to a cavalcade of chicken shit.
5) Eat a bullet and dream without worry.
-The world would be a better place if everyone had a hoverboard
Obesity is the either the #1, #2, or #3 leading causes of just about any terrible disease in the US. And yet people still can't even make minor cut backs or improvements in their diets. I understand that you can't always put in exercise or eat right, but I think many people use that excuse too liberally (I apologize if I used the incorrect word there). I find it rather odd that one of the world's most prosperous and advanced countries should be felled by laziness and gluttony, two of the seven deadly sins that we've been warned about for quite a while.
It's a good thing my family doesn't have a history of Alzheimer's. I should be good on the candy and fast food front, because all my family has is a history of diabe- oh shit
Too bad for the ice cream industry, that's all the mix in one. Yet, instead of being so worried about future diseases, let's eat right today. Try to keep stress down. Fruits and veggies, salads, chicken, if you're not a veghead. Maybe even some organic beef from time to time. Good wine, or grape juice. Sea salt. Herbs and spices and everything nicess. Maybe even some snails, minus the puppy dog tails. Beans till your arses erupt with echos of laughter, so abrupt. Rice if your feeling real nice. Fish to your hearts wish. Good breads, tortillas and bagels, plus all of the other good staples! Soon your body will feel so majestically harmonized, you'll have Al's rhymers with ease (versus alzheimers' disease.
Most people with Alzheimers have drunk coffee (even though they may not remember it) and so:
coffee -> Alzheimers! (EOD)
Sounds to me it's more likely only genetic factors since most of the old people I know who are starting to lose it had parents with Alzheimers. Besides, there have been studies that prove that vegetarians are severely deprived of nutrients vital to brain function....as if we needed a study to prove this. I look at it this way. Cow spends its life eating grass. Cow absorbs nutrients from grass. Cow gets slaughtered. I buy cow. I eat cow for a few days. I get the nutrients. It's just a more efficient delivery medium.
Now where did I put that cheese...
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'Super Size Me'. (I've been cutting down on the Chocolate Frosted Sugar Bombs)
...Lorenzo / I'm into kinky crustaceans. I just discovered internet praWn.