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Mad Scientist Brings Back Dead With "Deanimation"

mattnyc99 writes "Esquire is running a a jaw-dropping profile of MacArthur genius Marc Roth in their annual Best and Brightest roundup, detailing how this gonzo DNA scientist (who also figured out how to diagnose lupus correctly) went from watching his infant daughter die to literally reincarnating animals. Inspired by NOVA and funded by DARPA, Roth has developed a serum for major biotech startup Ikaria that successfully accomplished 'suspended animation' — the closest we've ever come to simulating near-death experiences and then coming back to life. From the article: 'We don't know what life is, anyway. Not really. We just know what life does — it burns oxygen. It's a process of combustion. We're all just slow-burning candles, making our way through our allotment of precious O2 until it becomes our toxin, until we burn out, until we get old and die. But we live on 21 percent oxygen, just as we live at 37 degrees. They're related. Decrease the oxygen to 5 percent, we die. But, look, the concentration of oxygen in the blood that runs through our capillaries is only 2 or 3 percent. We're almost dead already! So what if we turn down the candle's need for oxygen? What if we dim the candle so much that we don't even have the energy to die?' " The writer Tom Junod engages in what Hunter Thompson once called "a failed but essentially noble experiment in pure gonzo journalism." If you can suspend your inner critic for a time, it's a fun ride.

62 of 501 comments (clear)

  1. First Undead Post! by Anonymous Coward · · Score: 5, Funny

    Braiiiiins!

    1. Re:First Undead Post! by metlin · · Score: 5, Funny

      What do veggie zombies say?

      Graaaiiins. Grrraaaaaiiinnss. Gggrraaaaaiiiiinnnnssss.

      I'll be here all night, thank you.

    2. Re:First Undead Post! by JoshuaZ · · Score: 5, Funny

      What do dyslexic zombies say? Briaaannnns!

    3. Re:First Undead Post! by davidphogan74 · · Score: 5, Funny

      What do optometrist zombies say? Fraaaaaames!

    4. Re:First Undead Post! by vyruss000 · · Score: 3, Funny

      What do arthritic zombies say? Paaaiiinnns!

  2. Reanimator! by girlintraining · · Score: 4, Funny

    Klatu Verata Nictu!

    --
    #fuckbeta #iamslashdot #dicemustdie
    1. Re:Reanimator! by jebrew · · Score: 5, Funny

      necktie?

    2. Re:Reanimator! by jbezorg · · Score: 3, Funny

      It definitely was a "N" word

      --
      I've lost all my marbles except one & It's fun to test angular & centripetal acceleration in my skull
    3. Re:Reanimator! by Anonymous Coward · · Score: 3, Funny

      That's Klaatu you insolent clod!

    4. Re:Reanimator! by Eli+Gottlieb · · Score: 4, Funny

      Ia, Ia! Shub-Niggurath!

    5. Re:Reanimator! by Metasquares · · Score: 3, Funny

      heh, I read that as Vas Corp Por. I know exactly what that would do in a graveyard...

  3. Early Cryogenics & Ethical Problems by eldavojohn · · Score: 4, Insightful

    This reminds me of a This American Life episode I listened to (and you can too by clicking on Full Episode here). Basically it explores a very bad chapter of early cryogenics. Before I listened to that, I thought that this was pretty cut and dried ethically (dead bodies are dead bodies, do what you want) but you see how it negatively affects other people who misplace hope in this process.

    Also, isn't Ikaria the worst name to pick? "Hey, our company hopes to aim too high and fail hard." They should have gone with Promethea in my opinion.

    --
    My work here is dung.
    1. Re:Early Cryogenics & Ethical Problems by s.bots · · Score: 4, Informative

      In TFA it mentions that

      It's called Ikaria, after the island with regenerative sulfur springs mentioned by Herodotus.

    2. Re:Early Cryogenics & Ethical Problems by jollyreaper · · Score: 5, Funny

      Before I listened to that, I thought that this was pretty cut and dried ethically (dead bodies are dead bodies, do what you want) but you see how it negatively affects other people who misplace hope in this process.

      A corpse is a corpse
      of course, of course
      and you can't gain consent from a corpse, of course
      because a corpse is, of course
      by definition dead!

      --
      Kwisatz Haderach
      Sell the spice to CHOAM
      This Mahdi took Shaddam's Throne
    3. Re:Early Cryogenics & Ethical Problems by Hal_Porter · · Score: 5, Funny

      It would be ok if you had net access.

      --
      echo -e 'global _start\n _start:\n mov eax, 2\n int 80h\n jmp _start' > a.asm; nasm a.asm -f elf; ld a.o -o a;
    4. Re:Early Cryogenics & Ethical Problems by davolfman · · Score: 4, Interesting

      What's interesting is that we're talking metabolic suspended animation. It's actually a pretty old idea. I remember reading about it for the first time in "The Star are Ours!" an old Andre Norton scifi novel.

  4. DARPA! by staryc · · Score: 5, Interesting

    Is it any coincidence that DARPA is Sanskrit for arrogance in this situation?

    --
    The most perfidious way of harming a cause consists of defending it deliberately with faulty arguments. - Nietzche
  5. Whoa boy... by Chicken_Kickers · · Score: 5, Insightful

    I think this article will open up a can of worms on Slashdot. The issue I have here is that bringing someone back from suspended animation where they were alive to begin with is not the same as 'reviving the dead'. I think nature has been doing this in hibernating animals for millions of years. If someone could freeze a medically dead person and then make him alive again with his memories, personality etc. intact, (i.e. not cloning, which is already feasible) then they can claim they have revived the dead. Other than that, it is just playing with semantics.

    1. Re:Whoa boy... by eldavojohn · · Score: 3, Interesting

      The issue I have here is that bringing someone back from suspended animation where they were alive to begin with ...

      Here's a better question: When do you think anyone in their right mind will ok that procedure? Think about it, you're taking a perfectly alive human being and ... putting them at risk of death? For the purposes of? I know someone will compare this to the risk of life we took putting someone on the moon but I see little to no merit in this procedure.

      If you think they're going to run into federal problems, that's only the start of it. This is probably going to be a always-20-years-away technology although it does make for entertainment.

      --
      My work here is dung.
    2. Re:Whoa boy... by girlintraining · · Score: 4, Funny

      Well thanks for totally ruining our fun. Next you'll be telling us snacks are bad for us and we can't play slayers and vampires anymore with those colored sticks with string on them from that construction site nearby. They make great stakes you know! What's wrong with having a little fun, serious-face? You're almost as bad as that guy with the bright orange hat outside that's been swearing for the last hour.

      --
      #fuckbeta #iamslashdot #dicemustdie
    3. Re:Whoa boy... by QuantumG · · Score: 4, Insightful

      Meh. It'll be a standard procedure in 5 years. "Ok, so what the anesthetist is going to do is stop your heart. Then we'll cut two small incisions in your chest and I'll insert this tiny camera.. [blah blah blah, rest of the standard keyhole surgery speech] .. and once we're all finished, the anesthetist will start your heart again."

      This stuff isn't that revolutionary.. it's just a neat trick to stop you getting brain damage when you're not getting enough oxygen.

      --
      How we know is more important than what we know.
    4. Re:Whoa boy... by TheLazySci-FiAuthor · · Score: 5, Insightful

      Semantics, agreed.

      Of course, in true Slashdottian hyperbole, were this serum to be completely viable, I could see some kind of auto-release nano-canisters being injected into the bloodstream of soldiers, so that in the event of explosive death, an instant release of the substance could assure that all the pieces quickly 'go to sleep' and await pickup/cleanup by the wandering red cross medical roombas for delivery to the reconstruction/reanimation tent.

      That would be pretty close to dying and being brought back methinks.

      Might make a good extreme sport as well!

    5. Re:Whoa boy... by Matimus · · Score: 4, Interesting
      Seriously? If I was bleeding to death, and there was no equipment around to stop the bleeding enough to keep me alive, I would welcome this procedure.

      You are correct that there is no good reason to do this for fun, but if the choice is death or entering a potentially risky state of suspended animation, I will choose the later.

      Keep in mind that the majority of the research is for exactly that purpose.

      --
      GENERATION 25: The first time you see this, copy it into your sig on any forum and add 1 to the generation. Social exper
    6. Re:Whoa boy... by Anonymous Coward · · Score: 3, Interesting

      > Here's a better question: When do you think anyone in their
      > right mind will ok that procedure? Think about it, you're
      > taking a perfectly alive human being and ... putting them at
      > risk of death? For the purposes of? I know someone will
      > compare this to the risk of life we took putting someone on
      > the moon but I see little to no merit in this procedure.

      You are not being very imaginative.
      Imagine a sick patient, in need of a long and complex heart
      operation. Imagine that the risk of complications during the
      procedure is extremely high.
      Imagine that you could put the patient in suspended animation,
      perform the risky procedure, and 'reanimate' the patient only
      when his pieces are correctly put together.

      I think this is something worth pursuing, although it will
      not probably happen tomorrow or next week.

    7. Re:Whoa boy... by Emperor+Zombie · · Score: 5, Informative

      If you'd RTFA (shocking, I know), you'd see that DARPA was interested in it as a way of preventing wounded people from bleeding out. It's already being tested on humans.

      --
      I'm so excited I just made water in my pantaloons!
    8. Re:Whoa boy... by NIckGorton · · Score: 4, Insightful

      Here's a better question: When do you think anyone in their right mind will ok that procedure?

      You'd never ok that procedure any more than you would ok having CPR performed. (Though you might leave an advanced directive to prevent it in certain situations.) Its likely something that would be done should you have cardiac arrest in a medical setting (or with fast enough EMS response if it becomes a field treatment.)

      Its also likely something that would be done in order to facilitate transfer of a patient who will die quickly without specialized care unavailable at a given facility. For example, you get whacked on the head in an assault an sustain an epidural hematoma (big assed bleeding inside your skull outside your brain that can kill you rapidly by compressing your brain and causing your brainstem to be squeezed out the base of your skull). I diagnose that at my small community ER and plan to transfer you to the big tertiary care center 50 miles away. However as we await the helicopter you suddenly begin to show signs of brainstem herniation. At that point you are dead in minutes without a neurosurgeon. So I place you in suspended animation and we ship you to the surgeon who evacuates your hematoma and then you are reanimated.

      Pretty nifty. Though your HMO will probably deny payment because its 'experimental' or only allowed for epidurals on the right side of your head, not the left.

    9. Re:Whoa boy... by trouser · · Score: 5, Funny

      fun is always a good reason to do anything. Except for things that aren't fun. For example I breed weasels. Through selective breeding favouring weakness and mutations which yield no survival benefit in the wild I have created an army of blind, five legged weasels the size of turnips. They will only eat or procreate when encouraged with electric cattle prods. With my mutant weasel army I will rule the world! More importantly it's a blast. I've never felt so alive.

      --
      Now wash your hands.
  6. Re:Herbert West - Reanimator by incripshin · · Score: 5, Informative

    http://en.wikipedia.org/wiki/Herbert_West%E2%80%93Reanimator
    I don't know how I could have messed that up.

  7. Near death != death by morgan_greywolf · · Score: 3, Insightful

    You're either dead or you're not. It's rather binary. There's no continuum.

    1. Re:Near death != death by Wonko+the+Sane · · Score: 5, Funny

      You forgot about mostly dead.

    2. Re:Near death != death by Captain+Splendid · · Score: 5, Funny

      You're either dead or you're not. It's rather binary. There's no continuum.

      Schrodinger's cat says hi. Or maybe he doesn't.

      --
      Linux, you magnificent bastard, I read the fucking manual!
    3. Re:Near death != death by reginaldo · · Score: 5, Funny

      Whoo-hoo-hoo, look who knows so much. It just so happens that you can be MOSTLY dead as well.

      There's a big difference between mostly dead and all dead. Mostly dead is slightly alive. With all dead, well, with all dead there's usually only one thing you can do.

      Go through his clothes and look for loose change.

      /*obligatory miracle max

    4. Re:Near death != death by girlintraining · · Score: 5, Insightful

      Either you're dead or you're not--Tell that to someone who's brain dead. Or someone who's suffered a stroke that effects their brain stem, or people that suffer from being "locked in". Tell that to someone who 'died' on the operating table during heart surgery but 'came back'. What exactly constitutes being "alive" verus dead? Are self-replicating proteins "alive"? Because last I looked, prions are not alive though they can kill you (mad cow disease). And this isn't even discussing non-literal definitions of dead or alive -- such as being emotionally dead (suicidal thoughts anyone?), concepts of heaven and hell, etc.

      There is indeed quite a spectrum between dead and alive; Life has never been easy to classify and put into boxes, because the curious thing about it is you never observe the same thing twice looking at it.

      --
      #fuckbeta #iamslashdot #dicemustdie
    5. Re:Near death != death by TWX · · Score: 4, Informative

      People have been clinically dead (no pulse, no breathing, would not continue to live without specific processes of intervention) and have been successfully revived. Many have gone on to live perfectly normal lives, while others have been left dead too long and their tissues suffered for it, leaving them with reduced faculties. I wouldn't call it quite as cut and dried as dead or not. We can tell when someone is really, truly alive, and we can identify conditions when someone is really, truly dead, but there are plenty of conditions where one could be potentially alive or dead (with apologies to SchrÃdinger) and that further actions will determine what state a person goes into.

      --
      Do not look into laser with remaining eye.
    6. Re:Near death != death by girlintraining · · Score: 4, Funny

      Yes, your friend here is only mostly dead. Had he been all dead there would have been only one thing to do -- go through his pockets for spare change.

      --
      #fuckbeta #iamslashdot #dicemustdie
    7. Re:Near death != death by dingen · · Score: 5, Funny

      You're either dead or you're not. It's rather binary. There's no continuum.

      There's no "rather binary". It's either binary or it's not.

      --
      Pretty good is actually pretty bad.
    8. Re:Near death != death by Carnildo · · Score: 3, Insightful

      You're either dead or you're not. It's rather binary. There's no continuum.

      The people quoting The Princess Bride above do have a point: you can't draw a line and say "everyone on this side is dead, everyone on the other side is alive". Consider bacterial endospores: no significant chemical reactions are taking place inside the spore, and by most objective measures, they're "dead". But place one in the correct environment, and it will convert to an unambiguously-alive bacterium.

      Humans are far more complicated, with even more ways to blur the boundary between "alive" and "dead".

      --
      "They redundantly repeated themselves over and over again incessantly without end ad infinitum" -- ibid.
    9. Re:Near death != death by Emperor+Zombie · · Score: 5, Funny

      Sure there is! It's just like regular binary, except it only uses the numbers "one-ish" and "probably nothing".

      --
      I'm so excited I just made water in my pantaloons!
    10. Re:Near death != death by TapeCutter · · Score: 3, Interesting

      Although your points are valid they are rather narrow in that they implicitly define 'alive' as the potential for consiousness, the GP's point that doesn't make sense to you was that there is no black & white definition of 'alive'.

      For example the wood frog can allow itself to freeze solid for the winter and will thaw out in spring with no ill affects despite the fact it hasn't had a heartbeat or any sign of brain activity for months. By your tests the frog is dead during the winter and alive again in the spring.

      --
      And did you exchange a walk on part in the war for a lead role in a cage? - Pink Floyd.
  8. Holy moly! by grub · · Score: 5, Funny


    Quick, get him CVS commit access to all the BSD projects!

    --
    Trolling is a art,
  9. This needed for long space travel but warp / hype by Joe+The+Dragon · · Score: 3, Funny

    This needed for long space travel but warp / hyper drives are better.

  10. Aging is a disease by geekoid · · Score: 5, Insightful

    that will be cured.

    And no, overpopulation won't be a problem becasue humans, like all biological creatures will only expand to meet the amount of food that is available.
    The rest will starve.

    --
    The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    1. Re:Aging is a disease by josteos · · Score: 5, Funny

      The rest will starve.

      Until the hungry ones realize the others taste good with ketchup.

      --
      Save the Music; Save the World at http://www.TuneTriever.com (Our latest Android game)
  11. Space travel etc. by Chicken_Kickers · · Score: 5, Insightful

    Well, this could be useful in space travel, barring we develop hyperdrives. Sci fi have been playing around with sleeper ship concepts for decades. It might also be useful for people who have terminal cancer for example, who might want to opt to be frozen in the hope of a cure being developed during the interim (though there will be the problem of reintegrating into society after even just a few years). A more plausible use maybe is to put into suspended animation a critically injured person until he can be transported to a hospital and treated to minimise cell damage (assuming the serum does less damage).

    1. Re:Space travel etc. by M0b1u5 · · Score: 5, Insightful

      You overestimate how much society changes.

      Given the ENORMOUS gulf between 1900 and 2000, you could reanimate a person who died in 1908, and it would take them very little effort at all to adjust to 21st century life.

      Do you think if you were frozen now, you'd have trouble being resurrected in 2028? I think not. You'd love it.

      Humans are like that: adaptable.

      In fact, I'd go so far as to say you could resurrect an ancient Sumerian person with little or no difficulties.

      The situation would be no different to bringing a Papuan to New York city. They might not like it much, but they'd adjust pretty quickly.

      --
      How many escape pods are there? "NONE,SIR!" You counted them? "TWICE, SIR!"
    2. Re:Space travel etc. by Anonymous Coward · · Score: 3, Funny

      Space travel???? Forget that! Next thing you know, you wake up in 2491 dressed in horribly colored spandex being followed around by some little phallically shaped robot that sounds like Bugs Bunny. NO THANK YOU!!!!

    3. Re:Space travel etc. by Gr8Apes · · Score: 4, Interesting

      Try the enormous gulf just between 1995 and today.

      • the web
      • cell phones
      • death of in-country long distance fees
      • death of CDs
      • ipods and music downloads
      • death of VHS
      • Netflix
      • VoD
      • last and certainly not least: Google

      Go back another 10 years

      • computers
      • email
      • outsourcing of white collar jobs
      • access to 100s of TV channels and the death of "snow"
      • the rise (and fall) of casette tapes (8-track and reel-to-reel sucked, if you ever used either for storing and convenient playback)
      • the rise of CDs and artificially inflated prices leading to the rise of the current RIAA juggernaut
      • VCRs
      • death of rotary phones and the Ma Bell stranglehold on telecom

      There were huge similar sweeping changes for each decade all the way back to roughly the 1870s or so when the effects of the industrial revolution started directly affecting people's lives and livelihoods. And here's a hint: the degree of change is accelerating still, we'll probably see some of the most interesting times we can imagine, old Chinese curses not withstanding.

      --
      The cesspool just got a check and balance.
    4. Re:Space travel etc. by corbettw · · Score: 4, Insightful

      So what? Those things are just that: things. There are people living today who lived through all of those advances and didn't go into shock over them, why would you think someone getting caught up to all of it at once couldn't handle it?

      The things that people from 1955 would be most freaked out about now would be things like gay marriage, lowered blood alcohol levels in drunk driving laws, and having a black President-elect. Societal changes would be much more shocking. And even then, they would adjust, because as the GP pointed out, that's what humans do.

      --
      God invented whiskey so the Irish would not rule the world.
    5. Re:Space travel etc. by tibman · · Score: 3, Insightful

      Pretty sure horses still need to be shod and wooden fences built and gates fixed and bricks laid and mail delivered and snow shoveled and old ladies helped up the stairs (not exactly a job) and trash removed and books sorted and heavy things carried around. Not all jobs are "technical".

      --
      http://soylentnews.org/~tibman
    6. Re:Space travel etc. by Walpurgiss · · Score: 4, Funny

      But what if you woke up, and Sex was illegal, Salt was illegal, profanity was illegal, and Taco Bell was an up scale restaurant after the Fast Food Wars?

      You might adapt, but some grouchy old person might refuse to.

    7. Re:Space travel etc. by kalel666 · · Score: 3, Funny

      I'm posting on Slashdot. Done.

      --
      I HAVE CUBIC WISDOM THAT TRANSCENDS AND CONTRADICTS ONE DAY GODS
  12. Re:Herbert West - Reanimator by Anonymous Coward · · Score: 5, Funny

    I don't know how I could have messed that up.

    That's exactly what this guy'll say when he's locked himself inside his underground laboratory to keep out the hordes of flesh eating undead.

  13. Reincarnating? by grahamd0 · · Score: 3, Funny

    Esquire is running a a jaw-dropping profile of MacArthur genius Marc Roth in their annual Best and Brightest roundup, detailing how this gonzo DNA scientist ... went from watching his infant daughter die to literally reincarnating animals.

    I think they meant literally reanimating animals, but if I'm wrong, this guy's experiments would be interesting indeed.

  14. Not Dead... by JaneTheIgnorantSlut · · Score: 4, Funny

    Just pining for the fjords.

  15. Re:Burning the life at both ends. by denzacar · · Score: 3, Funny

    One where you could sleep over the economic crisis.

    Or get to live to eventually play Duke Nukem Forever.

    --
    Mit der Dummheit kämpfen Götter selbst vergebens
  16. Death is not a state. It's a prognosis. by Ungrounded+Lightning · · Score: 4, Interesting

    You're either dead or you're not.

    Define death.

    As the cryonicists say, "Death is not a state. It's a prognosis." It's a claim that the organism will not be restored from its current state to a level of function that is considered alive.

    Last time I looked (which was a while ago) trauma centers were regularly reviving victims who drowned in cold water and had been "dead" for half an hour. Surgeons were taking advantage of this by precooling patients who needed surgery that would leave the brain without blood flow for similar times. And research labs had perfused a dog with suitable protective substances, stopped its heart, cooled its body to freezing temperatures, left it that way for some time, then revived it. (And this guy has improved on that using H2S.)

    Were the drowning victims "dead"? Was the dog?

    There are people who are long since frozen - in full body or brain only - in the hope that they can some day be repaired (or built into a fresh body). If that is successful, are those people now "dead"? Or are they just resting at liquid nitrogen temperatures?

    --
    Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
  17. Re:Burning the life at both ends. by QuantumRiff · · Score: 4, Informative

    The kind of life where you could be transported from the battlefield, with its limited facilities, to a large, fully equipped hospital to patch you up, then woken up. There is a reason Darpa is funding him. Many soldiers die of reasons that they would easily survive in a hospital, with access to an unlimited supply of the best doctors. (unlimited because you can simply wait in that state until the doctor has helped other patients before you.)

    --

    What are we going to do tonight Brain?
  18. Re:Burning the life at both ends. by compro01 · · Score: 5, Insightful

    A useful kind.

    Doing surgery is like trying to fix a car while it's running. If this idea works, you could simply stop the engine for awhile, making many surgical procedures (heart bypass, for example) far, far, far simpler (and thus far less likely to get screwed up) and likely opening up a bunch of currently-impossible things, like spreading a long, complex procedure over multiple days, allowing the doctors to rest, which would help prevent mistakes caused by sleep deprivation.

    And of course, there's the sci-fi stuff like sleeper ships (as even at relativistic speeds, you're talking stupid lengths of time for interstellar travel.) or the old standby "Life is boring. Wake me up when X happens.".

    --
    upon the advice of my lawyer, i have no sig at this time
  19. Great so now by Orion+Blastar · · Score: 4, Funny

    we can finally unfreeze Walt Disney, and bring Elvis back to life. Maybe we could bring back George Washington and Abraham Lincoln to advise Barrack Obama? :)

    Ah for the good old days when only Jesus could raise the dead.

    --
    Remember, Slashdot does not have a -1 disagree moderation, and no, troll, flamebait, and overrated are not substitutes.
  20. Re:37 degrees? by sirsnork · · Score: 3, Informative

    Internally we are all 37 Degrees C. When someone takes your temperature, that's what they'll get as a result if you're not sick

    --

    Normal people worry me!
  21. Whoa by LtGordon · · Score: 5, Funny

    But, look, the concentration of oxygen in the blood that runs through our capillaries is only 2 or 3 percent. We're almost dead already! So what if we turn down the candle's need for oxygen? What if we dim the candle so much that we don't even have the energy to die?

    "Can I buy some pot from you?"

  22. Warm and dead by vik · · Score: 4, Interesting

    As an EMT volunteer we're told that a person isn't dead until they're warm and dead. Many people have been declared cold and dead, stored in the morgue, then scared the living crap out of the attendant complaining that it's bloody cold in there!

    Vik :v)