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Tooth Regeneration Coming Soon

Ponca City, We love you writes "For thousands of years, losing teeth has been a routine part of human aging. Now the Washington Post reports that researchers are close to growing important parts of teeth from stem cells, including creating a living root from scratch, perhaps within one year. According to Pamela Robey of the NIH. 'Dentists say, "Give me a root and I can put a crown on it."' In a few years dentists will treat periodontal disease with regeneration by using stem cells to create hard and soft tissue; they will take out a tooth that is about to fall, and reconnect it firmly to the regenerated tissue. Although nobody is predicting when it will be possible to grow teeth on demand, in adults, to replace missing ones, a common guess is five to ten years. Baby and wisdom teeth are sources of stem cells that could be 'banked' for future health needs, says Robey. 'When you think about it, the teeth children put under their pillows may end up being worth much more than the tooth fairy's going rate. Plus, if you still have your wisdom teeth, it's nice to know you're walking around with your own source of stem cells.'"

56 of 289 comments (clear)

  1. My opinion by Anonymous Coward · · Score: 5, Funny

    This research bites!

    1. Re:My opinion by Anonymous Coward · · Score: 4, Funny

      punbelievable!

  2. Going rate... by LostCluster · · Score: 4, Funny

    My parents were good to me, they adjusted the 25-cents a tooth they got for inflation... wonder what I'll have to pay my kids?

    1. Re:Going rate... by MichaelSmith · · Score: 4, Funny

      My parents were good to me, they adjusted the 25-cents a tooth they got for inflation... wonder what I'll have to pay my kids?

      My six year old son says two dollars. But then he has a DS game buying habit to suppport.

    2. Re:Going rate... by renegadesx · · Score: 4, Funny

      All these decades we thought the tooth fairy was a sweet rich angel sharing her wealth with poor kids... now we know the truth!

      The tooth fairy is a smart, cunning businesswoman planning to cash in big on her investment!

      --
      Make SELinux enforcing again!
    3. Re:Going rate... by Sinning · · Score: 2, Funny

      Hooray for reasons to punch babies!

  3. Well, now that just SUCKS. by ScrewMaster · · Score: 4, Interesting

    Plus, if you still have your wisdom teeth

    I don't have them ... my dentist finally convinced me to have them removed a couple years ago.

    --
    The higher the technology, the sharper that two-edged sword.
    1. Re:Well, now that just SUCKS. by MichaelSmith · · Score: 2, Funny

      Plus, if you still have your wisdom teeth

      I don't have them ... my dentist finally convinced me to have them removed a couple years ago.

      Wasn't there something recently about making stem cells from normal (I think) tissue in the reproductive system?

    2. Re:Well, now that just SUCKS. by JavaBasedOS · · Score: 4, Funny

      Plus, if you still have your wisdom teeth

      I don't have them ... my dentist finally convinced me to have them removed a couple years ago.

      Wasn't there something recently about making stem cells from normal (I think) tissue in the reproductive system?

      Why must it always boil down to choosing between something cool and losing our fertility? :(

    3. Re:Well, now that just SUCKS. by aliquis · · Score: 3, Funny

      Oh no, look at all the waste! I knew I should have saved it!

    4. Re:Well, now that just SUCKS. by raddan · · Score: 3, Funny

      That's fine, assuming you want a mouthful of sperm.

      /me ducks

    5. Re:Well, now that just SUCKS. by ceoyoyo · · Score: 5, Interesting

      If you can pull stem cells out of a wisdom tooth I don't see why you couldn't pull them out of any tooth you wanted. Sacrifice a back molar then regrow it, along with any other teeth you need replaced.

    6. Re:Well, now that just SUCKS. by bluefoxlucid · · Score: 4, Funny

      My girlfriend swears she likes the taste... I've decided I can accept that.

    7. Re:Well, now that just SUCKS. by Anonymous Coward · · Score: 2, Funny

      I don't have them ... my dentist finally convinced me to have them removed a couple years ago.

      I had mine pulled years ago as well. Now I keep them on a chain around my neck. I get lots of dates now!

    8. Re:Well, now that just SUCKS. by Anonymous Coward · · Score: 2, Informative

      That's what she tells me and the rest of the team, too!

    9. Re:Well, now that just SUCKS. by lawpoop · · Score: 2, Interesting

      I've had mine since they came in. ( Well, I guess that's a redundant statement )

      How/why did your dentist convince you to get them removed? Were they bothering you? Did you have other problems that they thought might be related? Has there been an improvement in your life?

      I've been bothered by migraine and cluster headaches, and neck and back tension for a long time. However, they started when I was 13, about five years before my wisdom teeth came in.

      --
      Computers are useless. They can only give you answers.
      -- Pablo Picasso
    10. Re:Well, now that just SUCKS. by Anonymous Coward · · Score: 5, Informative

      My girlfriend swears she likes the taste... I've decided I can accept that.

      Give her a treat by drinking lots of pineapple juice or eating bananas or papayas. Also, lay off the red meat, alcohol, and coffee.

      The fruits will make it sweeter while red meat, alcohol and coffee will make it bitter.

      What will you do when she wants more than you can produce? She will suck you out!

      Wheat germ can help you produce more.

    11. Re:Well, now that just SUCKS. by Aladrin · · Score: 3, Interesting

      A friend of mine had his removed because he was having headaches. Since I was also having headaches, I asked a doctor and his reply:

      No, that probably will not fix your head or jaw aches.

      He still recommended that I have them removed for other reasons, including the fact that the longer you wait, the more dangerous it is. There's always a chance that removal will tear a nerve in your cheek giving you a permanently numb cheek, among other dangers.

      As always, I am -not- a doctor. You should only take medical advice from a doctor.

      With this research, I'm wondering if I should have waited, though. The advice above about getting the stem cells from another back tooth is a good idea, though. Even if they (for some reason) couldn't regrow that back tooth, I'd gladly trade a back one for a front one.

      --
      "If you make people think they're thinking, they'll love you; But if you really make them think, they'll hate you." - DM
    12. Re:Well, now that just SUCKS. by jez9999 · · Score: 3, Funny

      'Something cool' would seem to be the sensible choice in that case. :-P

    13. Re:Well, now that just SUCKS. by MBGMorden · · Score: 5, Funny

      Somehow I just don't see it as a worthwhile goal to adjust one's diet to affect the taste of your sperm.

      --
      "People who think they know everything are very annoying to those of us who do."-Mark Twain
    14. Re:Well, now that just SUCKS. by AdamThor · · Score: 3, Funny

      If you have to evaluate your own results, then probably not.

      If you have a partner to do the experimental analysis then it may well be worthwhile.

      If you can gather a whole research team, then I'd say you should definitely go for it.

      --
      -- "Oh. This guy again."
  4. I have a friend who grew a tooth. by jcr · · Score: 5, Interesting

    A couple of years after having a tooth extracted, a new one came in, and his dentist was going over his older x-rays to make sure that the tooth coming in hadn't been there all along. Apparently it's a very rare thing, but not completely unheard of, and we all grow teeth at least once in our lives.

    -jcr

    --
    The only title of honor that a tyrant can grant is "Enemy of the State."
    1. Re:I have a friend who grew a tooth. by iluvcapra · · Score: 2, Informative

      The wisdom teeth are part of your permanent tier, they just erupt later. Back before we had good dentistry, it wasn't uncommon for an individual to be missing a tooth or two by the time they reached 25, and so when the wisdom teeth came in, they would rack in from the back and shift the others forward.

      Now that tooth loss is uncommon, wisdom teeth are regularly extracted, since they're liable to become impacted if there isn't space (from missing teeth) for them to grow in.

      And it's true that some people don't grow wisdom teeth. It's also true that some people only grow two, and some people grow six.

      --
      Don't blame me, I voted for Baltar.
    2. Re:I have a friend who grew a tooth. by jcr · · Score: 3, Informative

      Most people grow them twice! :)

      No, you usually grow them once. After that, it's just a matter of them moving into place.

      -jcr

      --
      The only title of honor that a tyrant can grant is "Enemy of the State."
    3. Re:I have a friend who grew a tooth. by tbird81 · · Score: 4, Interesting

      I'm not a dentist, but I have seen a child's skull with the mandible dissected at a museum. You can see a whole lot of adult teeth lined up under the baby ones.

      I was looking for a picture of this on the net, but couldn't find one quickly on google images. But take a look at this picture Baby teeth and the x-ray on this dental site.

      So I'd guess the wisdoms are just waiting under the baby teeth to pop up. Just a little longer than the others.

    4. Re:I have a friend who grew a tooth. by jacks0n · · Score: 3, Interesting

      I had three full sets of teeth too. I got hit in the face by my little sister when I was ~16 (don't ask), and the front teeth came right out. I could feel and see the nubs of the new teeth coming in right beneath them, and the teeth that came out were clearly not adult teeth though they weren't exactly like baby teeth either. Ultimately I lost all my teeth that year. Oddly, when I was ~24 my canines got loose and came out, with a new set below them, so 4 sets of canines. X-Rays confirm I'm on my adult teeth now, which sucks. I liked having spares.

      A few of my brothers and sisters had 3 sets of canines, but I was the only one with three complete sets out of 9 kids. I asked around my extended family, and on my mother's side heard of a few more people who had had three sets, so apparently there is some genetic basis for it.

  5. Hm. Great by imsabbel · · Score: 3, Funny

    Now the replacement after the painful procedure will ALSO be able to rot and hurt like the original. Fuck yeah !

    (only half joking. I was really happy after a root channel treatment, as that damn think was finally dead and not able to hurt anymore. In constrast to the year before.)

    --
    HI O WISE PRINCE. WHT TOOK U SO DAM LONG?
    1. Re:Hm. Great by Anonymous+Brave+Guy · · Score: 4, Interesting

      On the flipside, many of my teeth required some sort of work done on them after a course of treatment by a dubious orthodontist when I was a kid. Since then, even though dentists have always told me I have generally good oral hygiene, it seems like I have to get some filling or something replaced every few months, which is expensive and occasionally painful. I would give a lot to have real, intact teeth again, and articles like this give me some hope that one day it might even be possible. (I hear you on the root surgery thing, though: been there, done that too.)

      --
      If you disagree, post your argument. (-1, Overrated) isn't your personal censorship tool for views you don't like.
    2. Re:Hm. Great by ceoyoyo · · Score: 2, Interesting

      Instead of painful root canals you'd just yank the tooth and grow another in it's place.

    3. Re:Hm. Great by ceoyoyo · · Score: 2, Informative

      Less painful than some drilling, a filling or two, then later a root canal, or possibly repeated root canals if the first doesn't quite get it.

    4. Re:Hm. Great by KDR_11k · · Score: 2, Interesting

      Over here root canals are covered by the insurance and I don't think there was a waiting period at all when I got mine.

      --
      Justice is the sheep getting arrested while an impartial judge declares the vote void.
  6. Dental genetics by mcrbids · · Score: 4, Interesting

    One thing that's often ignored is that some people have naturally "harder" teeth than others. I, unfortunately, am "blessed" with the softer variety. I put out the effort: brush vigorously, regularly, flossing daily, etc. and my teeth are just horrible, and probably a third are basically just plastic. I am one of my Dentist's best customers.

    My wife, on the other hand, simply doesn't have to spend nearly as much effort on her teeth. She brushes and all, but she has gorgeous teeth and puts in only modest effort. I see the same in our children. Some have her teeth, put out little effort and consistently have nice, white teeth and no cavities, while others have mine, and brush regularly only to have cavities every single visit.

    Finally, I can grow new teeth!?!? Oh wait, they'll be *MY* teeth? With *MY* crappy-ass tooth genes?

    (to my wife) Eh, babe? (Ahem) Mind if I have one of your wisdom teeth?

    --
    I have no problem with your religion until you decide it's reason to deprive others of the truth.
    1. Re:Dental genetics by Arterion · · Score: 3, Interesting

      Don't brush too vigorously: you'll end up with with completely different problem of receding gums. If you don't have a really good electric toothbrush, get one. I use an Oral-B Triumph. I was totally amazed at how much I liked it. I thought it would just be a gimmick, but it's not. It's the best investment I've ever made into a gadget.

      I also find 30 seconds of Listerine after brushing helps a lot, too.

      Another thing I use daily is Johnson and Johnson Stim-U-Dent sticks. They take a little getting used to, but I really like them.

      --
      "That which does not kill us makes us stranger." -Trevor Goodchild
  7. Who you gonna call? Toothgrowers. by N!NJA · · Score: 4, Insightful

    the irony is that the people who would benefit more from such advancement (the toothless poor who cant bite a beefjerk at the age of 21) will not be able to afford such treatment.

  8. Crown? by Samah · · Score: 4, Funny

    'Dentists say, "Give me a root and I can put a crown on it."'

    This is the same thing that a king says when looking for a potential queen.

    --
    Homonyms are fun!
    You're driving your car, but they're riding their bikes there.
  9. 5 years my arse by QuantumG · · Score: 3, Insightful

    When are journalists going to learn that it takes 10 years to get from the lab to market? And when it comes to anything medical, add another 10 years for clinical trials.

    --
    How we know is more important than what we know.
  10. Damn... by pongo000 · · Score: 3, Insightful

    ...I'm glad that I've still got all four of my wisdom teeth! Sounds like they will be good insurance towards healthy teeth in my later years. Actually, I wonder if this biotechnology will spell the end to the "convenience" removal of wisdom teeth.

  11. Re:A quarter? by conureman · · Score: 2, Interesting

    I got a dime. Kids.

    --
    The cost of that cleanup, of course, will be borne by taxpayers, not industry.
  12. Where's my GM Strep Mutans? by Dun+Malg · · Score: 5, Informative

    Screw growing back teeth, I want to know when we can have the genetically modified Streptococcus Mutans. Like 5 years ago, researchers announced they'd developed a strain of s.mutans (the bacteria responsible for most tooth decay) that doesn't excrete lactic acid. Once subjects' mouths were inoculated, the modified s.mutans completely took over, pushing the damaging strain out. Once inoculated you're theoretically 99% cavity free for the rest of your life. Is the ADA lobbying to keep it off the market because fillings and such are such a big money maker? Wouldn't surprise me.

    --
    If a job's not worth doing, it's not worth doing right.
    1. Re:Where's my GM Strep Mutans? by Plantain · · Score: 5, Informative

      Where are they? In the final stages of FDA clinical trials.

      http://en.wikipedia.org/wiki/Caries_vaccine

      --
      No, but I did throw granola at a deaf person once
    2. Re:Where's my GM Strep Mutans? by John+Hasler · · Score: 4, Informative

      > Is the ADA lobbying to keep it off the market because fillings and such are such a big
      > money maker?

      You mean the way they lobbied to block flouridation and flouride treatments?

      (Hint for the dense: they didn't. Quite the contrary.)

      --
      Warning: this article may contain humor, sarcasm, parody, and perhaps even irony. Read at your own risk.
    3. Re:Where's my GM Strep Mutans? by cynical+kane · · Score: 2, Funny

      That's because their ultimate goal is not money but our precious bodily fluids.

  13. A dime?! Luxury! by Arthur+Grumbine · · Score: 4, Funny

    Back in my day when we lost our teeth we had to pay the tooth fairy $100 for each tooth we lost. She said the $100 was for "protection" - from tooth decay we assumed...of course we learned the awful truth when little Johnny refused to pay, and that crazy bitch knocked out the rest of his teeth with a baseball bat.

    A dime?! That we could have been so lucky!

    --
    Now that I think about it, I'm pretty sure everything I just said is completely wrong.
  14. Re:Stem cell research is starting to look good by PhrostyMcByte · · Score: 2, Insightful

    An embryo is not a fetus. But you can make up whatever "definitions" suit you...

  15. It's about time by symbolic · · Score: 4, Interesting

    One thing that has always puzzled me is that despite all the advances in technology, getting a crown is still VERY expensive. There has been no appreciable reduction in cost due to better manufacturing techniques, or better/cheaper materials. Compare this to say, lasik - when it was first introduced it cost about 4K per eye I think. Now it's a few hundred.

    1. Re:It's about time by ThrowAwaySociety · · Score: 2, Informative

      One thing that has always puzzled me is that despite all the advances in technology, getting a crown is still VERY expensive. There has been no appreciable reduction in cost due to better manufacturing techniques, or better/cheaper materials.

      My dad is a dental lab technician (the guys who make crowns) and to hear him tell it, there have essentially been no advances in technology or manufacturing techniques. Yes, the materials are better and the process is apparently more streamlined, with better models to work from, but they are still mostly custom made, by hand. (When was the last time you had something custom tailored?) And the labor force that does this is apparently aging and not growing as fast as demand.

      (This is my understanding based on what he's relayed to me. Any errors or misrepresentations are most likely mine, not his.)

  16. Re: Luuxury! by conureman · · Score: 2, Funny

    I always read that with a Yorkshire accent.

    --
    The cost of that cleanup, of course, will be borne by taxpayers, not industry.
  17. Re:If this is true... by Spatial · · Score: 3, Funny

    Careful now. Punching a dentist class in the mouth is a bad move. An enraged dentist can heal a mouth injury in mere seconds. In response they may trick you with their mirrors, and if they roll a critical during this time you'll be drilled asunder!

  18. Re:Stem cell research is starting to look good by Arthur+Grumbine · · Score: 2, Insightful

    I do apologize. You see, for me the differences between those terms are as important to me (while discussing the value of the individual life) as infant and toddler, or child and preteen, or adolescent and young adult.

    When I'm trying to convince someone that saving a life is important, I forget about how much some people care about keeping perfect distinctions between adjacent stages of human development. I will try to avoid this from now.

    --
    Now that I think about it, I'm pretty sure everything I just said is completely wrong.
  19. Re:Not so. It happens more than you'ld think by jcr · · Score: 3, Funny

    Was this posted by a python script that generates paranoid fantasies?

    -jcr

    --
    The only title of honor that a tyrant can grant is "Enemy of the State."
  20. Question: Can I regrow custom-designed teeth? by 2Bits · · Score: 3, Interesting

    The question is, can I regrow custom-designed teeth? What if I don't like my teeth in the first place? I don't want to regrow the same set of teeth again.

    I was born with a severe lack of calcium. By the age of 3, I still didn't have any tooth. Not that it didn't grow, but the teeth were just like powder. When I ate, the teeth that just appeared in the morning were smashed by any food and swallowed along.

    After taking a lot of calcium supplement (still do on a daily basis), eventually, they grew. the shape are fine, but they are grey. They are weak, cavities and rotten root canal are nasty problems. And that causes all kinds of gum problems, even with daily Listerine or salty water mouth wash.

    Since high school, I always have to work extra to make that extra 5000 to 6000 more than others, every year, to take care of the teeth. Not to mention that it had been an obstacle to self-confidence for so many years.

    Now, if can regrow my teeth, I certainly don't want to regrow the same set. Can I custom-design mine?

  21. Not in our lifetime by NicknamesAreStupid · · Score: 2, Informative

    There is more to growing a tooth than stem cells. You can't just plant teeth like seeds in dirt. It has to attach to the right blood supply and the right nerve. Teeth do not sit in bone; so you can implant them like titanium screws. They need a periodontal ligament which supports the tooth in the bone and allows it to flex. The ligament has to attach to the bone as well as the tooth. That is one reason they cannot transplant teeth or even move your own wisdom teeth to the first or second molar position in your mouth.

    It will happen, but it will take a lot longer than any researcher is willing to concede.

  22. Somewhere in Alabama... by daskrabs · · Score: 2, Funny

    ...a man known as Willie "One-Tooth" Johnson just shed a single tear of joy.

  23. How to infuriate the next generation of parents by nobodyman · · Score: 3, Funny

    When I see people with extreme body modifications like subdermal beads and spikes that protrude from the scalp, I wonder what their children of those people could possibly do to frustrate them.

    This article gives me the answer: in 30 years teenagers will grow teeth all over their body.

  24. How to store teeth today? by RichiH · · Score: 3, Interesting

    As someone who has smaller children in his extended family, I am wondering if there are any house-hold-compatible ways to save cells on teeth. Or should I just forget the whole thing?

  25. Dentistry is a scam by GuloGulo · · Score: 2, Insightful

    Have you ever noticed that the state of restorative dentistry is progressing rapidly every day, but the state of the art in preventive dentistry is still brush and floss?

    I'm no tin-foil hat guy, but this is one area I genuinely believe is being overlooked solely for the monetary benefit.

    --
    "The government grants you rights, not the other way around."-- beav007. Yes, these people really exist...