Slashdot Mirror


Healing Wounds With Diamonds

A team at Northwestern University, led by Dean Ho, has discovered that nanodiamonds are a wound's best friend. Insulin is very attracted to nanodiamonds and in addition to regulating blood sugar, insulin can accelerate the healing process and stave off infection in wound sites. Since the tiny diamond can be easily placed in a wound without causing further damage, this is an excellent way to get an increased amount of insulin there as well. From the article, "A substantial amount of insulin can be loaded onto the nanodiamonds, which have a high surface area. The nanodiamond-insulin clusters, by releasing insulin in alkaline wound areas, could accelerate the healing process and decrease the incidence of infection. Ho says this ability to release therapeutics from the nanodiamonds on demand represents an exciting strategy towards enhancing the specificity of wound treatment."

8 of 109 comments (clear)

  1. bling wound by L3370 · · Score: 3, Funny

    In other news...Debeers has just entered the Health care industry.

  2. Gives new meaning to the phrase... by ptelligence · · Score: 4, Funny

    Blood Diamonds

  3. Way to Lower Health Care cost.... by jameskojiro · · Score: 4, Funny

    Imagine what kind of Health insurance you would have to get for diamond treatment. You would have premiums of 10,000.00 a month.
    .
    Of course when we all have to go to Government run health care like Canada, we will have to wait in line for 3months for wound treatment and instead of nano-diamonds, we will have to make do with cubic zirconium dust covered in aspirin.
    .
    Thanks you scientists! It will end up being more effective to pray to Jesus to heal your wounds.

    --
    Tsukasa: All I really want, is to be left alone...
  4. Re:Why? by notarockstar1979 · · Score: 4, Funny

    Magic. If it were anything else they would have stated it in the article.

  5. Re:insulin by yabos · · Score: 4, Informative

    They don't use it to lower body fat. Insulin does one simple thing which is open your cells, both fat and muscle, to glucose. It does this by binding to the cell at the insulin receptor, which causes the cell's internal GLUT-4 protein to come from deep in the cell up to the surface. GLUT-4 opens the gateway for glucose to the cell which will often pull in other things(nutrients, water) along with it. Injecting insulin is not a good thing long term unless you are diabetic. Some body builders end up insulin resistant or diabetic by abusing it. Now the reason that they actually do it is because it's extremely good at what it does which is draw energy into your cells. Insulin is what we call an anabolic hormone and if combined with huge amounts of carbs(usually while on anabolic androgenic steroids as well), your muscles get a lot of glucose which gives you lots of energy, but also enhances growth and recovery if you are training the muscle.

  6. Re:Oh God... by Cornflake917 · · Score: 4, Insightful

    Remember when Nelly and a bunch of other Rappers put little bandages on their faces

    No. This is slashdot.

  7. Re:Good luck by GiMP · · Score: 3, Informative

    HMO is "health maintenance organization". Remember, we do not have national medicine in the USA, we instead have medical insurance companies. There are two primary types of plans one can get, an HMO or a PPO (Preferred Provider Organization), the difference is in which doctors you can see, how much you pay, and the process through which you must visit specialists.

  8. Re:Why? by cfa22 · · Score: 5, Informative

    The insulin molecule has two patches on its surface that are predominantly hydrophobic (water-hating) that likely help it to stick to the pure-carbon surface of (nano)diamond. The "nano" bit just insures there is a large amount of surface area for insulin to stick to per unit mass of diamond. The investigators only showed that their nanodiamonds can suck up a lot of insulin; they are far from proving their insulin-loaded nanodiamonds are useful for wound-healing. The investigators only speculate that insulin would act as a growth hormone (generally thought to be its minor function; the major function being the transsystem signal for organism-wide glucose homeostasis). They point out the pH in a typical wound could approach 10.5, which would facilitate insulin release from nanodiamonds. (Such increases in alkalinity in beta cells, the pacreatic cells that produce insulin, are thought to trigger its release.) Unfortunately, it might also compromise insulin's ability to dock with its receptor, a necessary requirement for its function (either as a growth hormone or in glucose regulation). Directly injecting insulin into wounds speeds healing (sometimes by 50%) (Zhang et al, J. Surg. Res. 142:90 (2007) link), so it seems like the investigators have a plausible path to follow.