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Healing Wounds With Diamonds

A team at Northwestern University, led by Dean Ho, has discovered that nanodiamonds are a wound's best friend. Insulin is very attracted to nanodiamonds and in addition to regulating blood sugar, insulin can accelerate the healing process and stave off infection in wound sites. Since the tiny diamond can be easily placed in a wound without causing further damage, this is an excellent way to get an increased amount of insulin there as well. From the article, "A substantial amount of insulin can be loaded onto the nanodiamonds, which have a high surface area. The nanodiamond-insulin clusters, by releasing insulin in alkaline wound areas, could accelerate the healing process and decrease the incidence of infection. Ho says this ability to release therapeutics from the nanodiamonds on demand represents an exciting strategy towards enhancing the specificity of wound treatment."

19 of 109 comments (clear)

  1. Why? by HasselhoffThePaladin · · Score: 2, Insightful

    The article leaves a lot to be desired. Can anyone explain why it is that insulin's attracted to diamonds, or more specifically, nanodiamonds?

    Apart from the "insulin = women" comments we're sure to get, I'm seriously wondering why.

    1. Re:Why? by notarockstar1979 · · Score: 4, Funny

      Magic. If it were anything else they would have stated it in the article.

    2. Re:Why? by PotatoFarmer · · Score: 2, Funny

      Well, obviously. 7th level Clerics have known about this sort of thing for years.

    3. Re:Why? by cfa22 · · Score: 5, Informative

      The insulin molecule has two patches on its surface that are predominantly hydrophobic (water-hating) that likely help it to stick to the pure-carbon surface of (nano)diamond. The "nano" bit just insures there is a large amount of surface area for insulin to stick to per unit mass of diamond. The investigators only showed that their nanodiamonds can suck up a lot of insulin; they are far from proving their insulin-loaded nanodiamonds are useful for wound-healing. The investigators only speculate that insulin would act as a growth hormone (generally thought to be its minor function; the major function being the transsystem signal for organism-wide glucose homeostasis). They point out the pH in a typical wound could approach 10.5, which would facilitate insulin release from nanodiamonds. (Such increases in alkalinity in beta cells, the pacreatic cells that produce insulin, are thought to trigger its release.) Unfortunately, it might also compromise insulin's ability to dock with its receptor, a necessary requirement for its function (either as a growth hormone or in glucose regulation). Directly injecting insulin into wounds speeds healing (sometimes by 50%) (Zhang et al, J. Surg. Res. 142:90 (2007) link), so it seems like the investigators have a plausible path to follow.

  2. bling wound by L3370 · · Score: 3, Funny

    In other news...Debeers has just entered the Health care industry.

  3. Get out your wallets... by vintagepc · · Score: 2, Funny

    Yay! Now when your GF wants a diamond all she has to is fall and scrape a knee...

    --
    Evolution - Est. 4500000000 B.C. Don't piss in the gene pool.
  4. Gives new meaning to the phrase... by ptelligence · · Score: 4, Funny

    Blood Diamonds

  5. New Age Dream by Sponge+Bath · · Score: 2, Funny

    The power of healing crystals finally comes true. Far out.

  6. Not only physical wounds by hcs_$reboot · · Score: 2, Insightful

    Diamonds often help to heal love's wounds as well.

    --
    Slashdot, fix the reply notifications... You won't get away with it...
  7. Re:insulin by ZackSchil · · Score: 2, Interesting

    Your body already has the right balance of insulin. Periodically injecting it is an incredibly stupid if it's for the sake of vanity. You could end up in the hospital for hypoglycemia. In the long term, you could develop insulin resistance followed by Type II Diabetes.

  8. How expensive could this treatment be? by Mitchell314 · · Score: 2, Insightful

    How easy is it to make nano-diamonds anyways? I'm wondering if there's a cheap way to make graphite on the small scale to order themselves like a diamond for at least a short period of time.

    --
    I read TFA and all I got was this lousy cookie
    1. Re:How expensive could this treatment be? by Jeng · · Score: 2, Informative

      There is a natural supply of nano-diamonds, and I can't imagine nano-diamonds being all that expensive to create.

      http://en.wikipedia.org/wiki/Presolar_grains

      The chemical vapor deposition method of producing synthetic diamonds should be able to create nano-diamonds pretty easy I would think.

      --
      Don't know something? Look it up. Still don't know? Then ask.
    2. Re:How expensive could this treatment be? by smellsofbikes · · Score: 2, Informative

      You take an oxy-acetylene torch, adjust it to a fuel-rich flame, and point it at a big piece of metal, then scrape off the stuff deposited on the metal and separate out the diamonds from the buckminsterfullerine from the soot. Here's a journal article and here's one of the many patents.

      --
      Nostalgia's not what it used to be.
  9. Way to Lower Health Care cost.... by jameskojiro · · Score: 4, Funny

    Imagine what kind of Health insurance you would have to get for diamond treatment. You would have premiums of 10,000.00 a month.
    .
    Of course when we all have to go to Government run health care like Canada, we will have to wait in line for 3months for wound treatment and instead of nano-diamonds, we will have to make do with cubic zirconium dust covered in aspirin.
    .
    Thanks you scientists! It will end up being more effective to pray to Jesus to heal your wounds.

    --
    Tsukasa: All I really want, is to be left alone...
  10. Re:the bad news: by x2A · · Score: 2, Insightful

    Yeah but that's not really important for those of us that live on that small island you may have heard of called "the rest of the world" (you may have seen our flag... it's like yours, but on fire) ... that said, Obama's plans for your health service really don't sound as doom and gloom as your local press makes out, just as our politions plans for us and our health service don't seem as doom and gloom as our local press makes out. So chill out, I'm sure they go through the cost/benefit calculations with a lot more rigour than your gut instinct has.

    --
    The revolution will not be televised... but it will have a page on Wikipedia
  11. Re:insulin by yabos · · Score: 4, Informative

    They don't use it to lower body fat. Insulin does one simple thing which is open your cells, both fat and muscle, to glucose. It does this by binding to the cell at the insulin receptor, which causes the cell's internal GLUT-4 protein to come from deep in the cell up to the surface. GLUT-4 opens the gateway for glucose to the cell which will often pull in other things(nutrients, water) along with it. Injecting insulin is not a good thing long term unless you are diabetic. Some body builders end up insulin resistant or diabetic by abusing it. Now the reason that they actually do it is because it's extremely good at what it does which is draw energy into your cells. Insulin is what we call an anabolic hormone and if combined with huge amounts of carbs(usually while on anabolic androgenic steroids as well), your muscles get a lot of glucose which gives you lots of energy, but also enhances growth and recovery if you are training the muscle.

  12. Re:Oh God... by Cornflake917 · · Score: 4, Insightful

    Remember when Nelly and a bunch of other Rappers put little bandages on their faces

    No. This is slashdot.

  13. Re:Good luck by GiMP · · Score: 3, Informative

    HMO is "health maintenance organization". Remember, we do not have national medicine in the USA, we instead have medical insurance companies. There are two primary types of plans one can get, an HMO or a PPO (Preferred Provider Organization), the difference is in which doctors you can see, how much you pay, and the process through which you must visit specialists.

  14. Re:Twilight Vampire Skin by gt6062b · · Score: 2, Funny

    Almost - until you realize that the vampires in Twilight ARE diamonds. They're tough to break They sparkle They're cold And the emotionally unstable lead female in the "story" will do anything for them.