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Scientists Write Memories Directly Into Fly Brains

TheClockworkSoul writes "Researchers at the University of Oxford have devised a way to write memories onto the brains of flies, revealing which brain cells are involved in making bad memories. The researchers said that in flies, just 12 brain cells were responsible for what is known as 'associative learning.' They modified these neurons by adding receptors for ATP, so that the cells activate in the presence of the chemical, but since ATP isn't usually found floating around a fly's brain, the flies generally behave just like any other fly. Most interestingly, however, is that the scientists then injected ATP into the flies' brains, in a form that was locked inside a light-sensitive chemical cage. When they shined a laser on the fly brains, the ATP was released, and the 'associative learning' cells were activated. The laser flash was paired with an odor, effectively giving the fly a memory of a bad experience with the odor that it never actually had, such that it then avoided the odor in later experiments. The researchers describe their findings in the journal Cell."

7 of 137 comments (clear)

  1. Bad odor by Tibia1 · · Score: 5, Funny

    The scientists later discovered that even fly's without this injected memory avoided the odor. One man was quoted saying "It smelled pretty bad."

    1. Re:Bad odor by dov_0 · · Score: 5, Insightful

      If only they could program them to avoid the smell of BBQ meat...

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      sudo mount --milk --sugar /cup/tea /mouth /etc/init.d/relax start
  2. Giving flies bad memories? by dov_0 · · Score: 5, Funny

    In my day we just ripped their wings off. This new stuff is REALLY sick...

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    sudo mount --milk --sugar /cup/tea /mouth /etc/init.d/relax start
  3. Re:Wait a second... by TheClockworkSoul · · Score: 5, Insightful

    Well, just a thought, but wouldn't one such possible control be shining the laser on flies without ATP receptors?

  4. NPR Science Friday by Snowblindeye · · Score: 5, Informative

    NPR's Science Friday had an interview with the one of the scientists this morning. You can listen to the segment here: http://www.sciencefriday.com/program/archives/200910161

  5. Re:Memory? Or an instinct? by Anonymous Coward · · Score: 5, Informative

    As you might guess, the article title and summary are incorrect. The scientists *didn't* write a memory into the fly's brain, they exposed it to something to memorize (the smell) and then artificially triggered the store-this-as-bad circuitry. Which is still cool and interesting and all that.

  6. Re:Why? by Anonymous Coward · · Score: 5, Funny

    Ahhhh....the beaches, the babes, all that free cake... I sure am gonna miss Vietnam.