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High Fructose Corn Syrup Causes Bigger Weight Gain In Rats

krou writes "In an experiment conducted by a Princeton University team, 'Rats with access to high-fructose corn syrup gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same.' Long-term consumption also 'led to abnormal increases in body fat, especially in the abdomen, and a rise in circulating blood fats called triglycerides.' Psychology professor Bart Hoebel commented that 'When rats are drinking high-fructose corn syrup at levels well below those in soda pop, they're becoming obese — every single one, across the board. Even when rats are fed a high-fat diet, you don't see this; they don't all gain extra weight.'"

41 of 542 comments (clear)

  1. HFC by Anonymous Coward · · Score: 5, Interesting

    That is because HFC is absorbed by the body in the same way that beer and alcohol is. In the liver. HFC also suppresses the satiety (hunger) signal so people tend to eat more.

    1. Re:HFC by Rei · · Score: 4, Insightful

      You do realize that high fructose corn syrup is actually a mixture of fructose and glucose, right? The ratio varies depending on the type of HFCS; many of them are around 50-50 (the two most common are 55% fructose and 42% fructose (HFCS-55 and HFCS-42, respectively). And you know what sucrose breaks down into in the stomach? A 50:50 glucose/fructose mixture.

      Its this that makes it somewhat of a stretch to find what could cause a difference (a number of studies find no difference between the two). One theory is that the imbalance between fructose and sucrose, however small, makes the difference. Another is that HFCS doesn't require acid hydrolysis in the stomach, and this somehow affects the results. Another is that people will eat more sweet food when sweetened with HFCS instead of sucrose, although that's questionable and is notwhat this particular study is talking about. But really, the overall evidence is doubtful. The AMA says that it's "unlikely" that HFCS contributes more to obesity than sucrose does.

      --
      The Spanish-English dictionary is out of ink.
    2. Re:HFC by tpjunkie · · Score: 5, Informative

      I am a (stressed out) med student studying for a GI physiology exam. Sugars must be broken down in the small intestine to monosaccharides to be absorbed, so sucrose becomes glucose and fructose, lactose (if you're not lactose intolerant) breaks down to glucose and galactose. Glucose and galactose are absorbed via co-transport with sodium via transport proteins. This requires a standing Na+ gradient in the cell, maintained by the Na-K pump, which requires the expenditure of energy. Fructose on the other hand enters the cell by simple facilitated diffusion through the GLUT-5 protein, meaning its transport out of the intestinal lumen requires no energy expenditure. Biochemically it it can enter the glycolytic cycle and is rapidly metabolized in much the same way as glucose.

    3. Re:HFC by BobPaul · · Score: 5, Informative

      HFCF is fructose and sucrose. Fructose is absorbed by the small intestine. Sucrose (table sugar) is broken down in the stomach and small intestine into 1 glucose molecule and 1 fructose molecule, which are then both absorbed by the small intestine. So, either way you get fructose, big deal, right? That's the conventional wisdom.

      But lets look further. If you eat 1 tablespoon of HCFC 55 (equal in sweetness to 1 tablespoon sucrose), you get .55 tablespoons of fructose and .45 tablespoons of sucrose. That sucrose is turned into half fructose and half glucose before entering the bloodstream. So in reality you ate .775 tablespoons of fructose and .225 tablespoons of glucose. This is significantly more fructose than if you had eaten 1 tablespoon of sucrose. And if you're consuming sugar water (as in the study) or lots and lots of soda, you're consuming far more than a tablespoon.

      Of course your claim that it's "absorbed ... in the same way that beer and alcohol is. In the liver" isn't quite correct. They're all absorbed by the small intestine, but it's true they are metabolized by the liver, albeit in completely different ways. What's might be important about the liver, though, is that it's not regulated by insulin. While glucose can be metabolized by any of the bodies cells, insulin regulates blood glucose levels. Fructose is only processed by the liver and is indifferent to insulin levels. So (in a layman's, but more detailed explanation) when you eat that 1 tablespoon of table sugar, you get half a tablespoon of unregulated sugar and half regulated. Eat the HFCF55 and most of the sugar is unregulated.

      As an aside, honey is almost identical in composition to HFCF55, so if you meet any holistics bemoaning HFCF and championing honey, you can tell them to screw off.

    4. Re:HFC by inKubus · · Score: 5, Interesting

      HFCS is created with an enzymatic process. The HFCS food companies buy is dirty. It's mostly fructose and glucose but it also contains the enzymes used to convert the corn starch. You can't remove it all, apparently. And the standards are based on very small serving sizes. When people are drinking 50-100g a day of it, this enzyme builds up in the human system and attaches to other starch and performs the same conversion process to sugar. Normally this process takes more energy but with the unnatural enzyme it doesn't, and therefore it causes more efficient breakdown of starch. These people also tend to have a bag of chips or fries with their 50-100g of corn syrup. This means all of that becomes sugar. Since the body can't use the sugar, insulin is released and reactions occur and "bada-bing" FAT.

      See Alpha-amylase, Glucoamylase, and Xyloase.

      --
      Cool! Amazing Toys.
    5. Re:HFC by pydev · · Score: 5, Informative

      Fructose is the culprit. But there are differences. Pure fructose is hard to absorb. Fructose in fruit is released only slowly. Both are probably OK. Fructose in sucrose needs to be split off before being absorbed, which seems to limit its rate; at normal sucrose concentrations, the fructose is also absorbed more slowly than the glucose.

      HFCS is the worst of the bunch: it doesn't need to be split, and the 1:1 fructose/glucose ratio is ideal for rapid absorption, and both sugars peak simultaneously, putting a large load on the liver.

      So, you're fine with moderate sucrose consumption (disaccharides) and eating fruit till you burst (fructose+fiber). Pure fructose is iffy. And HFCS is a no-no.

    6. Re:HFC by DigiShaman · · Score: 4, Interesting

      I was skeptical, but still on the fence with this issue. But after killing my soft drink consumption in favor of pure carbonated water, I've shed quite a bit of weight in the span of a few months. I've also felt less hungry.

      I'm now a believer that HFCS should be avoided whenever possible. Every now and then is fine to consume products with it as in with anything else in moderation. But when it becomes a major staple of your diet, bad stuff starts to happen to your body.

      Everyone do yourself a favor, drop the Mt Dew. It's bad mojo.

      --
      Life is not for the lazy.
    7. Re:HFC by cayenne8 · · Score: 5, Insightful
      "I'm now a believer that HFCS should be avoided whenever possible. "

      Trouble is...HFCS is in fucking everything..

      Just try to find something as simple as a loaf of bread, or salad dressing without HFCS in it.

      When I started reading labels, trying to cut carbs on the few processed foodstuff I do buy...I was amazed to find how pervasive that shit is in everything out there...

      --
      Light travels faster than sound. This is why some people appear bright until you hear them speak.........
    8. Re:HFC by pydev · · Score: 4, Informative

      Parent is about 50% factually incorrect. See the earlier med student's response for the true metabolic process.

      Bullshit. Go read up on the facts yourself before you start mouthing off:

      http://www.medbio.info/Horn/Time%201-2/carbohydrate_metabolism.htm

  2. Not as bad as something else by Pojut · · Score: 4, Interesting

    HFCS is bad, but not NEARLY as bad as Crystalline Fructose, which makes an appearance in beverages like Vitamin Water. Do some google searching on it...it's much harder to break down in your liver than HFCS.

    http://www.thefitshack.com/2007/03/28/what-is-crystalline-fructose/ for some examples.

    1. Re:Not as bad as something else by Mindcontrolled · · Score: 5, Informative

      Sorry, but that blog seems to be a wee bit on the crackpot side of things. The body does not really care how the fructose is administered - when it arrives in the intestine, it is in solution anyway, so no difference whether it comes crystalline or as HFCS. The effect should be the same. The problems that are pointed at in that post are probably true, however. Fructose triggers a lower insulin response than glucose, so the hunger persists despite caloric intake. Also, fructose is metabolized mostly, if not only, in the liver, which causes stress on the organ.

      Usual table sugar - sucrose - is a disaccharide made from one molecule of fructose and one of glucose. The glucose part triggers the insulin production, which signals that you have taken in calories. So, if you use normal sugar instead of HFCS, your body knows that you got energy way faster. That seems to be the main obesity mechanism associated with HFCS.

      --
      Ubi solitudinem faciunt, pacem appellant.
    2. Re:Not as bad as something else by Mindcontrolled · · Score: 4, Informative

      You are right on the mechanism. However, there is another step. There is a liver-only fructokinase, which has a way higher Km than the hepatic glucokinase - so basically all fructose in the bloodstream is pulled by GLUT2 into the liver and retained there by phosphorylation through the hepatic fructokinase. The glucose also enters the liver via GLUT2, but is phosphorylated way more slowly, so a significant amount is not retained hepatically by the phosphorylation reaction. The additional liver stress and the main metabolic difference results from the fact that the subsequent metabolizing of F6P in the liver is insulin independent.

      Hope that suffices for starters. For more details, I'd have to break out the literature... and I am stressing my own liver with a decent red wine way too much for that at the moment ;)

      --
      Ubi solitudinem faciunt, pacem appellant.
  3. Re:Queue . . . by Anonymous Coward · · Score: 5, Informative

    Glad to oblige! This story was posted on Science Daily yesterday. They included the following:

    Editor's Note: In response to the above-mentioned study, The Corn Refiners Association issued a statement titled "Gross Errors in Princeton Animal Study on Obesity and High Fructose Corn Syrup: Research in Humans Discredits Princeton Study" (http://www.corn.org/princeton-hfcs-study-errors.html). This link is provided for information only -- no editorial endorsement is implied.

  4. Patriotism and Elections by Anonymous Coward · · Score: 4, Interesting

    Well, that isn't going to matter as long as Iowa and the corn farmers have the political power that they do.

    If there is one good thing about the new "Obamacare" bill, it's that unhealthy things will cost the government money. The downside is they will now have one more reason to regulate.

  5. Avoid eating HFCS fed rats by Ranger · · Score: 4, Funny

    Problem solved.

    --
    "You'll get nothing, and you'll like it!"
  6. Its the subsidies that are the problem by Kenja · · Score: 4, Insightful

    Stop giving our tax money to farmers to over-grow corn and lower the price to the point where corn syrup is cheaper then sugar. Problem solved.

    This would also solve the hemorrhagic ecoli problem in cattle farms by making grass cheaper then corn husks for feed.

    --

    "Have you ever thought about just turning off the TV, sitting down with your kids, and hitting them?"
    1. Re:Its the subsidies that are the problem by Anonymous Coward · · Score: 5, Insightful

      Actually, government subsidies that make corn cheaper are only half the problem; they're just making the corn syrup cheap.

      Government price supports for sugar are the other half -- trade barriers that stop us from importing cheap sugar from places like brazil that would love to sell it to us make sugar expensive.

  7. Skepticical: Study Results are inconclusive by axjms · · Score: 5, Informative

    Arstechnica.com covered this same study the other day. Their writeup is better than mine would be so why don't you read their article? http://arstechnica.com/science/news/2010/03/does-high-fructose-corn-syrup-make-you-fatter.ars

    The abridged version of the abridged version is that this study does not conclusively prove much of anything.

    --
    It is not enough to succeed, others must fail. - Gore Vidal
  8. Re:From the institute of Duh? by CheshireCatCO · · Score: 4, Insightful

    It's pretty much common knowledge that cheaper substitute ingredients are almost always unhealthy.

    I distrust "common knowledge, especially this bit. Bear in mind that if you find a case where the cheaper alternative is more healthy, people would pretty much go with it and you'd never think about it as it's a no-brainer. The trouble with that is that it tends to bias your perception, as you've shown and can easily keep you from examining a new option because it is cheaper. (In fact, this has been found to be the case: people won't buy products they think are too low in price even when the quality is as good or better. I wish I had my source handy for that.)

  9. Re:Queue . . . by MBCook · · Score: 4, Informative

    Ars Technica covered this a few days ago, and their analysis (as opposed to the publicity blurb the university made up) said the study basically came out a wash. Some groups saw gains, some didn't, but there was no clear pattern.

    I'm in the "HFCS should be avoided" camp at the moment, but this study doesn't really prove anything.

    --
    Comment forecast: Bits of genius surrounded by a sea of mediocrity.
  10. Re:Interesting by larry+bagina · · Score: 5, Insightful

    The sugar industry had something to do with the problem. Specifically, pushing for import quotas in the early 80s that increased the price. As a result, manufacturers switched to corn syrup and the candy industry moved to Canada and Mexico. The jobs lost from the candy industry most likely outnumber the jobs saved by the import quotas.

    --
    Do you even lift?

    These aren't the 'roids you're looking for.

  11. RE: Eating HFCS Rats (Obligatory Quote) by tarsi210 · · Score: 4, Funny

    Clark: Where's Eddie? He usually eats these goddamn things.
    Catherine: Not recently, Clark. He read that squirrels were high in cholesterol.

  12. Re:Gatorade switching... by Anonymous Coward · · Score: 4, Informative

    Gatorade used to not use HFCS a few years ago. I noticed when they switched to using HCFS and contacted their customer relations department. Here's the response I got from Gatorade:

    To:
      Subject: RE: Gatorade Thirst Quencher , REF.# 026139934A
      Date: Tue, 26 Jun 2007 12:58:35 -0500

      RE: Gatorade Thirst Quencher , REF.# 026139934A

      Bertrand:

      Thank you for contacting us about the High Fructose Corn Syrup
      (glucose-fructose syrup) in Gatorade Thirst Quencher. The important
      thing to know is that our formula has not changed. Gatorade contains
      the same scientifically proven blend of three carbohydrates -
      glucose, sucrose and fructose - in specific ratios.

      The glucose and fructose in Gatorade are essential functional
      ingredients required for rapid fluid absorption (an important
      component of hydration) and effective energy delivery. High-fructose
      corn syrup is glucose and fructose, and the body handles these sugars
      in the same way it handles the glucose and fructose provided by
      fruit.

      By way of background, carbohydrate sources do not contain only one
      type of sugar. For instance, table sugar (sucrose) is actually about
      50% glucose and 50% fructose.

      In the US, the term "High Fructose Corn Syrup" applies to both HFCS
      55 which is used in virtually all soft drinks (55% fructose with the
      remainder primarily glucose), and HFCS 42 used in Gatorade (42%
      fructose and the remainder primarily glucose.) In formulating
      Gatorade we use the HFCS 42 together with sucrose to create a blend
      that is appropriately sweet to encourage drinking, contains glucose
      for immediate use by the body, and yet does not contain too much
      fructose which, in large quantities, can cause intestinal distress.

      For weight maintenance, nutritionists agree that a sugar is a sugar
      and that it doesn't matter what your sugar source is. It just
      matters how much you consume. Many experts agree that HFCS has been
      unfairly demonized as a culprit in the obesity epidemic with no
      credible body of scientific research to support this notion.

      The Gatorade formula is continually tested by research scientists
      around the globe and proven on the world's best playing fields. We
      conduct ongoing research through the Gatorade Sports Science
      Institute to explore ways in which we can continue to deliver the
      best products, with the most effective ingredients, to our consumers.

      We hope this information helps you to make a more informed decision,
      Bertrand.

      Gina
      Gatorade Consumer Response

      Original Message:

      Hi. I just wanted to let you know that I am very disappointed in your
      Gatorade product since you started using high-fructose corn syrup as
      one of the ingredients.I used to specifically buy Gatorade rather
      than Powerade because of the fact that the later always contained
      HFCS. But now I will be avoiding both products.
      Thanks
      Bert R
      EMAIL*MESSAGE*END

  13. FOOLS! Drink the refreshing beverage . . . by StefanJ · · Score: 4, Insightful

    . . . that nature INTENDED you to drink.

    Coffee.

  14. give me more of that by Jodka · · Score: 4, Insightful

    Cane sugar is far more efficient to produce than corn sweetener but is primarily produced in tropical and subtropical regions outside of the United States . The agribusiness lobby in in the United States pays off politicians to restrict imports, driving up the price of sugar within the the U.S. to above that of corn syrup. Without import restrictions on sugar, all those products you buy which are sweetened with corn syrup would be sweetened with sugar instead. And cost less.

    You can blame the agribusiness lobby and the protectionist whores in the U.S. congress for this situation. It is a clear-cut case of government power expended to benefit he corrupt few at the expense of the many.

    --
    Ceci n'est pas une signature.
  15. It's all about the fiber by bunratty · · Score: 5, Interesting

    All fructose is processed by the liver in the same way as alcohol. That includes fruit juice.

    All this changes in the presence of fiber. If you eat a piece of fresh fruit, the fiber in the fruit changes the way the fructose from the fruit is absorbed so it's not such a huge shock to the liver.

    The bottom line is that if you eat carbohydrates, you should make sure it's with plenty of fiber. In other words, eat pieces of fruit, vegetables, and whole grains, just as nutritionists have been telling us for years. On food labels, I look for a % USRDA of fiber greater than or equal to the % USRDA of carbohydates, or grams of fiber at least 1/10 the grams of carbohydrate. It makes you feel more full with less food and prevents the sugar rush and crash from your liver absorbing the carbs too quickly.

    --
    What a fool believes, he sees, no wise man has the power to reason away.
    1. Re:It's all about the fiber by Arthur+Grumbine · · Score: 4, Funny

      Fruit juice != fruit.
      Drinking a tall glass of orange juice is the equivalent of eating 6~8 oranges, but without the fibers.
      Your liver treats the massive sugar dump much differently than eating the equivalent # of [fruit].

      The FDA wants to toss fruit juices into the same category of "bad" drinks as sugar laden sodas.

      That can't be right! I have it on good authority that drinking 1 oz. of Mona Vie acai berry juice is even healthier than 12 servings of fruits and vegetables. It comes from a super fruit, from the Amazon jungles! In fact, recent studies have shown that just purchasing a case of these stylish bottles may have an immediate positive effect on your interpersonal relationships (with any and all family and friends who have invested in the authorized reseller program). So, I say "Bah!" to your "science". Mona Vie has what plants crave! It's got electrolytes!!

      --
      Now that I think about it, I'm pretty sure everything I just said is completely wrong.
    2. Re:It's all about the fiber by Norwell+Bob · · Score: 5, Insightful

      All fructose is processed by the liver in the same way as alcohol. That includes fruit juice.

      All this changes in the presence of fiber. If you eat a piece of fresh fruit, the fiber in the fruit changes the way the fructose from the fruit is absorbed so it's not such a huge shock to the liver.

      Fruit juice != fruit. Drinking a tall glass of orange juice is the equivalent of eating 6~8 oranges, but without the fibers. Your liver treats the massive sugar dump much differently than eating the equivalent # of [fruit].

      The FDA wants to toss fruit juices into the same category of "bad" drinks as sugar laden sodas.

      Exactly true, and yet millions of (nutritionally) uneducated mothers and/or fathers insist that their children drink plenty of juice (most of which is probably only 10% real fruit juice to begin with), instead of soda... because it's "healthy".

      I won't go off on my usual rant about the terrible food pyramid we've been brainwashed with since the 60s ("eat a shitload of bread, but NO FATS!"), but the bigger problem I'm seeing every day is just an utter ignorance about what people put into their body, or an unwillingness to try something different.

      "It says LEAN Cuisine on the box! That means I'll lose weight by eating it."

      My dad taught me something when I was younger, probably without even meaning to... if you can't pronounce all the ingredients, you shouldn't eat it. Of course, as a kid, I ignored that advice and just ate whatever tasted good. My mother did her best, but she grew up in an Italian household, which means a lot of pasta and other starches. When she went back to work, the fridge was filled with microwaveable "food", that I could nuke whenever I thought I was hungry. Guess who was a fat kid who sucked at sports, couldn't keep up with friends when there was running, biking, climbing, or jumping was involved? Guess who grew up to be a fat adult who tried all the same shit (pills, "diet" meals, "magic" exercise apparatus, etc.) as many other fat people, with the same results... still fat.

      It took a combination of a rough period in my life, combined with pure dumb luck... I was really low and, rather than drown myself in booze, I decided that I'd had enough, and that it was time to work on me. I got an email from a major men's magazine, offering a 30-day free trial of a book (which I've shilled on /. before), the title of which appealed to desire to be more of a man than I saw in the mirror at the time. The price of the book was less than a night at the local watering hole, so I went for it. When it arrived, first I thumbed through it. There was a lot of *common sense* stuff in there that just hadn't occurred to me before. So, I went back and READ it. Many an a-ha moment. Then I went back again and applied it. Now, at the risk of sounding like a braggart, I'm one of the most fit guys in the office. People are constantly asking for, and then either disregarding or outright refuting my advice. The result is, they're still fat, and I'm still not.

      Bottom line is, there's no magic pill, there's no silver bullet, there's really no secret. Back in the caveman days, right up to a half century ago, you almost had to try to get fat. Now, the food manufacturers (think about that phrase for a moment) are pumping chemicals into their products to make them taste better, cheaper. When I was a kid, McDonald's was a once-in-a-while treat. Now it's considered by many to be a viable option for all three major meals. People get in their car and drive to the store a block away. Hell, I see parents put their kids in the van and drive TO THE END OF THE DRIVEWAY to wait for the bus. People would rather wait in their car for 20 minutes in the Dunkin' Donuts drive through than park, get out, and be in and out of the place in 2 minutes. Schools have dropped gym class to save money and make more time for standardized tests. My oldest son tells me they don't really

  16. Re:Queue . . . by eldavojohn · · Score: 5, Interesting

    If the rats had free access, how did they control for the amount consumed?

    Your criticisms may be apt but I would like to point out that after listening the evil shroud surrounding HFCS I decided to do an experiment with myself to see if eliminating HFCS from my diet while eating the same as I always have would cause me to lose or gain weight.

    And I had to make sure only to buy things at Trader Joes since my local grocery store carried but one loaf of bread with no HFCS in it and it was hilariously marked up as some organic bullshit.

    The problems didn't stop there. HFCS is quite literally everywhere. It's a preservative, a sweetener, everything. It got to be really ridiculous. After about a month of the whole charade my weight was about the same but I had been having wild cravings of ketchup (no, I wasn't pregnant). After satisfying this with some baked potatoes and french fries here and there loaded with ketchup, it dawned on me to inspect the label of my Heinz ketchup bottle. Fucking HFCS. Seriously? Upon returning to the store the "organic" ketchup is ridiculously expensive.

    Due to government subsidies and advanced food science, you cannot control your intake of HFCS. It's bloody impossible in today's America. I don't know how to fix this but you can be damned sure the Corn lobby likes it this way. I'm not saying it's as evil as trans fats or bad cholesterol but holy hell is it pervasive and uncapitalistically inexpensive!

    --
    My work here is dung.
  17. Re:Queue . . . by smaddox · · Score: 5, Informative

    Sugar in general should be avoided. Fructose, which is the bad half of sugar and HFCS, is the culprit. It can only be processed by the liver, and during processing it wreaks havoc on the body's systems for controlling hunger, satiation, insulin, etc.

    Take the time to watch this talk by Robert H. Lustig, MD, UCSF Professor of Pediatrics in the Division of Endocrinology. It might save your life (by extending your life).

  18. Re:Corn Lobby Response submitted... by jeko · · Score: 4, Funny

    Yep, I can see that commercial too.

    Soft focus. Sunrise. Dew on the stalks. A ladybug rouses from slumber. Woman in her natural beauty walks barefoot through soft rows. A newborn baby is cradled in the arms of a woman who has, I promise you, never given birth.

    The cutline/voiceover -- "Corn syrup. Made from nature. As natural as Hollywood breasts."

    --
    He put his boots up on the table and made a face. "The sig," he smirked. "You can waste your life in search of the sig."
  19. Re:In humans too... by confused+one · · Score: 4, Informative

    It's not an insightful "Duh". While it's not totally new, this is one of the first long term studies comparing consumption of different forms of sugar. The study showed there's a distinct difference between consuming equal amounts of sucrose from sugarcane and fructose from corn. Even the rats that were fed twice as much sucrose didn't gain weight like the rats being fed fructose.

  20. water switching... by city · · Score: 4, Insightful

    Really you're going to split hairs on this? Are you a long distance runner? I'm guessing no, so just drink water. It's really not that hard to just jump cold turkey and drink water all the time. It's free and there's no sugar or chemicals.

    --
    I am a v1ral sig. Plse c0py me and h3lp me spread. Thank y0u?
  21. Re:Queue . . . by mosb1000 · · Score: 4, Insightful

    If you eat foods that only use it as a sweeter, your hunger will still be regulated and prevent you from over-eating. For example, you wouldn't eat a 24-oz steak, I hope, because you would be quite full long before you could finish). On the other hand, most people seem to have a bout as easy time drinking an 8 oz can of soda as a 24oz bottle, even though the 24-oz is 3 times larger.

    The same goes for candy, if you replace if with bread, you have no hope of eating as many calories (and that's saying a lot because most people are capable of eating quite a lot of bread).

    Use common sense, you don't need to cut high-fructose corn syrup out of you diet completely to dramatically reduce your consumption of it. Simply avoid eating foods where the majority of the calories come from high-fructose corn syrup and you body will take care of the rest.

  22. Re:Queue . . . by RyanFenton · · Score: 5, Informative

    Make your own ketchup - it's REALLY easy, actually - just google for recipes. It's pretty much just tomato, vinegar, onion powder, and sugar (salt and oil optional), plus perhaps a little starch to get the right texture. Buy canned tomatoes in bulk, throw a can or so of them into a blender with everything else, cook and stir until smooth and even, then put it into a container in the fridge. Cleanup is just running water over everything. 15 minutes work for as much as you want to make. Incidentally, a little more sugar/oil/vinegar makes it into french dressing.

    There you go - good ketchup without HFCS.

    Ryan Fenton

  23. Re:Queue . . . by AK+Marc · · Score: 5, Interesting

    It's just the corn industry. The restrictions on sugar imports drive up the price so that sugar can't win (it can compete, but companies will take HFCS at 5% less or whatever). Then, because sugar beets would be barely cheaper and sugar cane could be grown in some areas, they get price subsidies on the corn. So importing the cheap sugar cane sugar is expensive, and growing it here results in reduced yields that can't compete with the subsidized corn.

    It's the same reason that marijuana is illegal. The cotton lobby made it illegal because they feared hemp. Then it became a moral issue (that oddly, no one had about tobacco and we had just swung the other way on with alcohol) and we exported our morals to the rest of the world. But at least the rest of the world tastes our HFCS and doesn't use it...

  24. Re:Queue . . . by Z34107 · · Score: 4, Insightful

    No, it's just the corn industry. The corn belt states are stupidly influential, and have managed to maintain sugar tariffs and corn subsidies. If you can get real sugar, it would be much more expensive to use than corn syrup.

    Nobody else seems to care. It directly benefits a lot of states, and the image of the Great American Small Family Farm has persisted in the popular imagination since we told the British where to stick their import taxes. If people are even aware of the subsidies, they're not seen as "handouts to big Agribusiness", but help to the mostly non-existent poor struggling farmers.

    Most other businesses are still considered "evil." Not sure why agriculture gets a free pass.

    Note, I don't mean to be insulting by this, I'm genuinely interested...

    Thanks for minding our delicate nationalist sensibilities. Brittle people like me appreciate it.

    --
    DATABASE WOW WOW
  25. Re:In humans too... by Ifandbut · · Score: 5, Funny

    One thing seems for certain, Laboratory Rats are a miserable lot. They seem to be susceptible to cancer and just about everything else you can imagine. Why not test something really hardy instead? Why not politicians?

    Rats are much better human analogs then politicians.

  26. Actual paper does not support that conclusion by harlows_monkeys · · Score: 4, Insightful

    The data in the actual paper doesn't support the conclusion in the title of the Slashdot story.

  27. Re:Queue . . . by deglr6328 · · Score: 4, Interesting

    I would like to endorse the sentiment expressed by Ars and expand upon it. Since I have access to most scientific journals, a couple days ago when this study was first published, but before any secondary analysis appeared on the web, I printed it out and took it home to read. I read scientific papers all the time (usually physics and chemistry), probably hundreds of papers per year, so I like to think that I'm pretty familiar with how good science is done and what constitutes a well designed, rigorously conducted investigation.

    The impression I got while reading this paper, is that it is a total piece of crap. It is confusingly written to begin with, but there are serious problems with methodology, controls, conclusions, assumptions about caloric intake and claimed statistical significance. It's a joke. Which, I guess is why it's published in an obscure journal with a pathetic 2.7 impact factor. Two sites explaining the problems in more detail are the Skeptic's Guide to the Universe forums at: http://sguforums.com/index.php/topic,26925.15.html and this blog post by Marion Nestle (a New York University professor in the department of nutrition, food studies, and public health with a Ph.D. in molecular biology): http://www.foodpolitics.com/2010/03/hfcs-makes-rats-fat/

    None of this told me how Princeton, of all places, could publish such a shit study though.....until I noticed this at the top of the paper that all the authors are from the Uni's PSYCHOLOGY department. Oh, I guess that's how.

    --
    - "Hear that?! The percolations are imminent! Cease your ingress!"
  28. Re:In humans too... by Svartalf · · Score: 4, Informative

    Heh...

    There's been a few other long-term studies that were done that were claimed "inconclusive" prior to this one. Most of them showed there was a serious problem with HFCS, but this one goes further to show that it's worse than many thought of the stuff.

    If you're counting calories- it's identical. That's what the producers of HFCS would have you believe is all that matters.

    The problem is that it isn't identical. Not even close.

    The fructose is in an immediately available fashion to your body, which means it's absorbed on the spot, unlike sucrose which has to be cracked apart first. From there it lies in your blood stream until your liver can utilize it. Your liver absorbs and converts some of this fructose into it's roughly one day's store of glycogen. Once it has a day's worth of reserve, it starts converting the rest as it gets to it into triglycerides and fatty tissue within the liver (Look up "fatty liver disease" via Google...). While it's waiting to be converted the pancreas sees the sugar levels rise and tries to pull the sugar OUT of the blood stream by increasing insulin levels. Unfortunately, only glucose responds directly to the insulin part of your hormone system- fructose is largely processed by your liver and only your liver. This has the predictable effect of yanking the glucose out of your blood stream. At some threshold, the body detects problems caused by the sugars being ripped out of your system by that and starts producing glucagon which orders the liver to start converting the glycogen in it's store back into glucose. Over time, this swinging, the triglycerides, and the other stuff going on combine to provide leptin resistance and insulin resistance- which are the hallmark signs of Type 2 Diabetes, something we're supposedly having an "epidemic" of in the "Western" world.

    And this doesn't even get into the traces of mercury and other chemicals you're exposed to when you eat HFCS as part of your diet.

    In the end, while you do need Fructose, you don't need the quantities that the Western populace seem to consume, nor do you need or want it in the form that we're exposed to it.

    --
    I am not merely a "consumer" or a "taxpayer". I am a Citizen of the State of Texas