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Acupuncture May Trigger a Natural Painkiller

Pickens writes "USNWR is reporting that the needle pricks involved in acupuncture may help relieve pain by triggering the natural painkilling chemical adenosine. There are also indications that acupuncture's effectiveness can be enhanced by coupling the process with a well-known cancer drug — deoxycoformycin — that maintains adenosine levels longer than usual. Dr. Maiken Nedergaard of the University of Rochester Medical Center and her colleagues administered half-hour acupuncture treatments to a group of mice with paw discomfort. The investigators found adenosine levels in tissue near the needle insertion points was 24 times greater after treatment, and those mice with normal adenosine function experienced a two-thirds drop in paw pain. By contrast, mice that were genetically engineered to have no adenosine function gained no benefit from the treatment." Read below for some acupuncture skepticism engendered by other recent studies.
However, many remain skeptical of acupuncture claims. Ed Tong writes in Discover Magazine that previous clinical trials have used sophisticated methods to measure the benefits of acupuncture, including 'sham needles' (where the needle's point retracts back into the shaft like the blade of a movie knife) to determine if the benefits of acupuncture are really only due to the placebo effect. 'Last year, one such trial (which was widely misreported) found that acupuncture does help to relieve chronic back pain and outperformed "usual care". However, it didn't matter whether the needles actually pierce the skin [paper here with annoying interstitial], because sham needles were just as effective,' writes Tong. 'Nor did it matter where the needles were placed, contrary to what acupuncturists would have us believe.'"

215 comments

  1. This just in by DevConcepts · · Score: 1

    Old news
    "Hieroglyphs and pictographs have been found dating from the Shang Dynasty (1600-1100 BCE) which suggest that acupuncture was practiced along with moxibustion."
    http://en.wikipedia.org/wiki/Acupuncture#Antiquity

  2. Impressive by chocapix · · Score: 3, Funny

    So, poking the skin with a sharp object triggers the release of painkillers by the body? I'm impressed.

    1. Re:Impressive by arndawg · · Score: 1

      hehe. That's why I love habanero or bhut jolokia. Basicly the same thing. Hurt yourself to get the good old adenosine feeling.

    2. Re:Impressive by EdZ · · Score: 1

      And more importantly, you can easily trick the body into releasing painkillers by making the brain think it's receiving/about to receive a painful stimulus. The chakra points (or chi/ki/whatever) nonsense may be total bunk, but the placebo effect here is measurable, and could potentially be exploited in actual medicine if it's effects can be reliable induced. A reduced requirement for painkillers could be of use in 3rd world countries where aid supplies may not always be available.

    3. Re:Impressive by Clueless+Nick · · Score: 1

      I once had a habanero laced masala dosa at a fancy eatery in SF. I thought I'd try to flaunt my 'credentials'.

      Ohhh my gourd!

      Anyways, lots of traditional therapies for pain relief depend upon capsaicin, some depend upon poisons such as bella donna, etc. etc.

      meh

      --
      Chat with other atheists http://secularchat.org
    4. Re:Impressive by ryzvonusef · · Score: 1

      "The chakra points (or chi/ki/whatever) nonsense may be total bunk" Tell that to the Hyuuga clan and see what happens ;-P But I agree, this placebo thing is awesome, why not use it on purpose? After all, in a tablet, isn't most of it composed of non-active ingredients? Make a tablet totally made of the non-active stuff, label it "Medicinol" and give it to people. If the problem still persists, then use the real thing. Useful in weeding out the Hypochondriacs :D

      --
      I am an ACCA student. Got a query on Accountancy/Finance? Maybe I can help!
    5. Re:Impressive by hedwards · · Score: 1, Interesting

      They're not bunk, I'm not sure how else one would explain my tendency to jump when somebody behind me is about to put their hand palm down on my shoulder. Strikes me as just as reasonable an explanation as any of the other possible ones.

    6. Re:Impressive by JamesP · · Score: 1

      So, poking the skin with a sharp object triggers the release of painkillers by the body?
      I'm impressed.

      Yes, but please let's keep homeopatic on this one ok.

      Don't try this with a sword, it won't be better than a needle.

      --
      how long until /. fixes commenting on Chrome?
    7. Re:Impressive by Ellie+K · · Score: 1

      Ummm so how old is this revelation that "Acupuncture May Trigger a Natural Painkiller"? 20 years, 30 years? When Nixon went to China, a God-awful long time ago, one of the journalists that came along for the trip had an appendicitis. He had a successful appendectomy, with part of the anesthesia, I believe the initial part, done with acupuncture. I read that in Newsweek. Why are we even discussing this on slashdot now in 2010?

      --
      tempus fugit
    8. Re:Impressive by noidentity · · Score: 1

      So Neo wasn't such a tough guy after all, with all those pins in his muscles in the first movie! He was just enjoying natural painkillers.

    9. Re:Impressive by Anonymous Coward · · Score: 0

      This isn't news to those of use who practice Kung-Fu as a hobby.

    10. Re:Impressive by ffreeloader · · Score: 3, Interesting

      Yeah, and the therapies based on capsaicin actually work, and without serious side effects. I use capsaicin regularly, both internally and externally.

      I suffer from a lot of headaches and over-the-counter medications do nothing for them. The only prescription meds that work have narcotics so they aren't really an option because of the frequency of my headaches, and I don't like the side effects as enough narcotics to kill the pain also make me high enough that everyday life--driving, working, etc... aren't really possible.

      I take 2 to 4 cayenne capsules with food, depending on the heat rating of the cayenne, or eat a spicy meal with the heat coming from habenero peppers in home-made meals(say a bean burrito with 1/4 - 1/2 of a diced habenero in it), or the spices used in traditional Thai cooking in a restaurant meal(4 out of 5 stars on the heat level)--we have a very good local Thai restaurant run by a Thai immigrant who's one of the best cooks I've ever seen--and a headache severe enough to make my eyes very sensitive to light will disappear in a matter of minutes.

      At those levels of heat there is no pain associated with the cure either as I eat spicy food on a regular basis, although what I think is bland most people say burns their mouth.

      --
      "while democracy seeks equality in liberty, socialism seeks equality in restraint and servitude." de Tocqueville
    11. Re:Impressive by the_one(2) · · Score: 1

      Overusing placebo makes people resistant thus making them useless! We all know what happened when we overused antibiotics! We don't want the same thing to happen to placebo drugs

    12. Re:Impressive by riT-k0MA · · Score: 4, Interesting

      I hate to break it to you, but it sounds like the headaches are caused by Capsicum/endorphin withdrawl...

      >Headache starts
      >Eat chilli
      >Headache stops
      >Body goes into withdrawl
      >Headache starts
      etc...

    13. Re:Impressive by Anonymous Coward · · Score: 0

      USNWR is reporting that the needle pricks involved in acupuncture may help relieve pain

      I know a prick that is a real PAIN ...

    14. Re:Impressive by ffreeloader · · Score: 1, Flamebait

      I hate to break it to you, but you're a complete idiot. You know, at the babbling idiot level of intelligence. I'm surprised you can read and write.

      I've suffered from frequent bad headaches since I was 8 or 9 years old and stumbled upon this remedy in my mid-30's. IOWs, and hopefully you'll be able to understand this with your level of intelligence, I suffered for decades with the MDs able to do nothing for me but feed me narcotics for the pain, which is not exactly a sustainable solution. Most of the time I just suffered through them as too-frequent requests for pain killers would bring on a doctor's accusations of being a con artist looking for drugs.

      I just happened to eat a spicy meal one day when I had a bad headache coming on, and realized less than a half-hour later my headache was gone, which was not a common occurrence as once a headache sets in it's around for a day or more. The next time I had a headache I made myself a spicy burrito and it worked again. I found that spicy food worked every time over an extended period of time. Later I learned about capsaicin and tried the cayenne capsule method. It worked too. Because of this it's been 20+ years now since I've needed a prescription for a headache.

      I gradually worked up a tolerance to the heat in the food so it doesn't bother me, and I now consider lesser levels of spice to be bland, but the same amount of pepper gives me the same relief now that it did more than 2 decades ago when I first realized it worked.

      Like I said to start with, you're a babbling idiot.

      --
      "while democracy seeks equality in liberty, socialism seeks equality in restraint and servitude." de Tocqueville
    15. Re:Impressive by The+Bean · · Score: 5, Insightful

      Sure, maybe he is wrong, but you're a bit of a douche for calling him an idiot for merely suggesting the possibility.

      Re-read your first post, based on that it's a perfectly legitimate suggestion.

      I think you should apologize and thank him for caring enough to reply to your post.

      Hug it out you guys.

    16. Re:Impressive by Anonymous Coward · · Score: 0

      I think you underestimate instinctive ability to track awareness. Animals demonstrate the same feat. A human would - much more capably than you - after being isolated in wilderness for 10 years. We don't realize quite how severely our senses are diminished by living in civilization and individual safety.

    17. Re:Impressive by Mad-Bassist · · Score: 1

      And here I thought it simply felt good when it stopped.

      "You heard of yin-yang?" ... "Yeah" ... "Okay, this needle, we're gonna stick in your yin-yang!" —Acupuncture, Cheech & Chong, Let's Make a New Dope Deal comedy album

      --
      "The only legitimate use of a computer is to play games." - Eugene Jarvis
    18. Re:Impressive by damien_kane · · Score: 1

      Overusing placebo makes people resistant thus making them useless! We all know what happened when we overused antibiotics! We don't want the same thing to happen to placebo drugs

      Getting resistant to sugar pills... large portion of the population at least overweight or obese... I'm not sure where the drawbacks here are

      Bring on the Place-Bo-brand medicinol.

    19. Re:Impressive by osu-neko · · Score: 1

      Sure, maybe he is wrong, but you're a bit of a douche for calling him an idiot for merely suggesting the possibility.

      Re-read your first post, based on that it's a perfectly legitimate suggestion.

      I think you should apologize and thank him for caring enough to reply to your post.

      Hug it out you guys.

      You must be new here. ;)

      --
      "Convictions are more dangerous enemies of truth than lies."
    20. Re:Impressive by fustakrakich · · Score: 1

      Damn man! Sounds like you're having a headache right now... Take a couple of chiles and sleep it off.. You remind me of the woman with the headache in the old commercial, “Mother, please! I’d rather do it myself!”

      --
      “He’s not deformed, he’s just drunk!”
    21. Re:Impressive by osu-neko · · Score: 1, Insightful

      Ummm so how old is this revelation that "Acupuncture May Trigger a Natural Painkiller"?

      If that's all you got out of the story... that part isn't news. However, if you had better reading comprehension, you'd be able to pick out the parts that are news. I'm pretty sure when Nixon went to China, the journalist in question (a) failed to identify the source of the painkilling effect as adenosine, (b) failed to determine that the effect is enhanced by the use of deoxycoformycin, (c) failed to quantify either of these effects in clinical and scientifically reproducible ways. If I'm wrong on this, please let me know. Otherwise, your comment seems kinda idiotic, like you didn't even manage to read the summary here successfully...

      --
      "Convictions are more dangerous enemies of truth than lies."
    22. Re:Impressive by Anonymous Coward · · Score: 0

      I hate to break it to you, but you're a complete idiot. You know, at the babbling idiot level of intelligence. I'm surprised you can read and write.

      Wow, it may help with the pain, but it leaves the irritability. It's probably PMDD.

    23. Re:Impressive by Reziac · · Score: 1

      Endorphin release due to pain from the heat = no more headache.

      I know someone who uses a good whipping as a remedy for menstrual pain -- same principle, different endorphin trigger.

      --
      ~REZ~ #43301. Who'd fake being me anyway?
    24. Re:Impressive by Anonymous Coward · · Score: 0

      I use a club, it really works, the scientific word of the painkilling state is 'unconsciousness'.

    25. Re:Impressive by turgid · · Score: 1

      and a headache severe enough to make my eyes very sensitive to light will disappear in a matter of minutes

      Are these headaches migraines? I get them of varying intensity, caused by stress. I've had some so bad that I've gone blind for a few hours. A few months ago, my GP prescribed Migard for them. It works very well. The side-effects I experience are dry mouth and very sensitive (to touch and heat) skin. It's worth it for the relief from the headaches. I often don't need to take any painkillers with them.

    26. Re:Impressive by Dogtanian · · Score: 1

      So Neo wasn't such a tough guy after all, with all those pins in his muscles in the first movie! He was just enjoying natural painkillers.

      Speaking of films then, this guy must have an addiction to painkillers...

      --
      "Slashdot - News and Chat Sites Deviant". (Click "homepage" link above for details).
    27. Re:Impressive by fishexe · · Score: 1

      You must be new here. ;)

      With a five-digit ID? I think not...just 'cause yours is four, you don't need to flaunt it. ;-)

      --
      "I don't care about the Constitution!" --Bill O'Reilly, November 17, 2009
    28. Re:Impressive by Anonymous Coward · · Score: 0

      There is no need to call him an idiot for not knowing things about your situation and making a judgement based on what you said in the first post.
      It seems you have zero ability to look at something from a different perspective.

    29. Re:Impressive by ffreeloader · · Score: 1

      Sure, maybe he is wrong, but you're a bit of a douche for calling him an idiot for merely suggesting the possibility.

      Re-read your first post, based on that it's a perfectly legitimate suggestion.

      I think you should apologize and thank him for caring enough to reply to your post.

      Hug it out you guys.

      Ummm.... Let's take a look at this sort of objectively.

      1. Did he "suggest" something, or just make a pronouncement? He made a pronouncement. There was no wording that could be considered as suggesting anything. It was, paraphrased, Hey, idiot, don't you know the difference between abuse of something and the use of something? What's more, his wording ridicules everything I said worked for me.

      2. What evidence did he have on which to base his pronouncement? None. He didn't even ask under what circumstances had led me to conclude that capsaicin works on my headaches. Why? If he was actually trying to be kind and suggest something with no ulterior motives why didn't he ask about why I think capsaicin works? No, instead he assumes the worst of me.

      3. What is the implication of his pronouncement? That I'm stupid enough to overindulge/overuse of the active ingredients in hot peppers to the point that it actually is the cause of my headaches, rather than the remedy for them.

      4. Where is his evidence for the conclusion he had to have reached to imply what he did in #3? He had none. How arrogant do you have to be to reach that kind of conclusion about another person about which you know absolutely nothing?

      5. His "suggestion" was insulting and out of line. He implied about me what I openly said about him.

      6. Where's your outrage at his arrogance and condescension?

      --
      "while democracy seeks equality in liberty, socialism seeks equality in restraint and servitude." de Tocqueville
    30. Re:Impressive by MightyDrunken · · Score: 1

      I hate to break it to you, but it sounds like the headaches are caused by Capsicum/endorphin withdrawl...

      Talk about jumping to conclusions. Capsicum analgesic effect is probably little to do with endorphins as popularly thought. It interacts with the TRPV1 receptor which causes the burning pain. The interesting part is that endocannabinoid anandamide is an activator of this system and paracetamol is also an agonist to TRPV.

      A related phenomena to the chilli high (in my mind) is the runner's high. There seems to be a debate if the effect is caused by endorphins, anandamide or some other mechanism. As in most real life cases it is probably a result of many different systems including these. Which may not only explain the runner's high but the pain relief many experience due to exercise. But either way I have not heard of people suffering from head aches because they haven't had their run!

      I couldn't find any evidence for an endorphin withdraw as such, the opiates have many symptoms related to withdrawal so if ffreeloader is also experiencing the following symptoms before his chilli hit you may be on to something. :)

      sweating, malaise, anxiety, depression, priapism, extra sensitivity of the genitals in females, general feeling of heaviness, cramp-like pains in the limbs, excessive yawning or sneezing, tears, rhinorrhea, sleep difficulties (insomnia), cold sweats, chills, severe muscle and bone aches; nausea and vomiting, diarrhea, cramps, and fever.

  3. More Effective Painkiller by Anonymous Coward · · Score: 0

    Damage his nervous system so he cant feel from the neck below

    1. Re:More Effective Painkiller by Anonymous Coward · · Score: 0

      Bad treatment. Won't work.

  4. News for Hippies, Stuff that Smelly by Anonymous Coward · · Score: 2, Funny

    Where's Cartman when you need him!

  5. Acupuncture by MrKaos · · Score: 1

    At least we know what the point is now.

    --
    My ism, it's full of beliefs.
    1. Re:Acupuncture by rawtatoor · · Score: 2, Informative

      To make it clear what acupuncture is: It was believed that directly massaging another person with your hands drains your energy over the long term, leading to a shorter life. The needles were introduced to eliminate the need for this contact. Also the acupuncture/qigong meridians along with the 5 phase theory are the practical result of several thousands of years of Chinese culture. P-R-A-C-T-I-C-A-L. Yes, you can call it psuedo science, but you would be ignoring the many many many instances of real people affected in real ways.

    2. Re:Acupuncture by Anonymous Coward · · Score: 0

      Exactly! People must remember that there are more people in human history that has been treated with acupuncture than with antibiotics. And up to today antibiotics have killed more people than acupuncture... That is PRACTICAL, FACTUAL. Millions of people felt relieved of several sorts of "sufferings" by that practice. That is factual and when you think that medicine objective should be to relieve people of suffering, than you must rethink a few things.

    3. Re:Acupuncture by osu-neko · · Score: 1

      Yes, you can call it psuedo science, but you would be ignoring the many many many instances of real people affected in real ways.

      No, not ignoring at all, just noting the lack of true science involved. I'm sure it works, I'm sure it provides a great benefit to many people, and I'm utterly convinced that it's pseudo-scientific BS. The fact that it's the result of practical testing ensures that it works. The fact that it's post hoc rationalization for what's actually occurring rather than an attempt to determine what actually is occurring makes it pseudo-science.

      --
      "Convictions are more dangerous enemies of truth than lies."
  6. An apt reminder... by TuringTest · · Score: 5, Informative

    ...for those trying to defend the scientific method saying that a pseudoscience "cannot possibly work" because "there aren't any known methods through which it could operate".

    The way to disprove a non-effect is by showing it indistinguishable from chance. Not by declaring that we can't think of any possible explanations.

    --
    Singularity: a belief in the "God" idea with the "demiurge" relation inverted.
    1. Re:An apt reminder... by Joce640k · · Score: 5, Interesting

      Anybody who follows the scientific method knows at least one mechanism for acupuncture, ie. placebo, and I don't think many would shake their heads in abject disbelief if you say "irritating some part the body will produce natural pain killers". The skepticism will appear if you start saying "it matters where you stick the needles" and stuff like that.

      Real "pseudoscience" is stuff like astrology, water divining, channeling the dead, perpetual motion, expensive HiFi tweaks, etc.

      --
      No sig today...
    2. Re:An apt reminder... by Eudial · · Score: 1

      Because acupuncture has been poked and prodded so extensively by skeptics (pun not intended), there is now a great deal of evidence for it's effectiveness. Which is very much the scientific way: By resisting new ideas until there is undeniable evidence for them, we get a very strong protection against ideas that are wrong.

      --
      GAAH! MY PRINTER IS ON FIRE!!! PUT IT OUT! PUT IT OUT!
    3. Re:An apt reminder... by philgp · · Score: 1

      I don't believe you - that pun surely *was* intended!

    4. Re:An apt reminder... by Antique+Geekmeister · · Score: 3, Informative

      Except that most of the best evidence shows that the "chi energy", the use of needles rather than pressure, and the use of it for treatment of body parts that are nowhere near the needle are complete nonsense. So scienctific testing shows that even the stopped clock of the magical thinking surrounding acupuncture can be right twice a day, and can even predict now what that twice a day will be.

      I once spent a long, sad hour with an MD who tried to tell me that acupuncture worked because the nerves it stimulates are faster than pain nerves. I tried to explain to her the concepts of phase delays: if the pain came first by more than a matter of milliseconds, the pain signal was already present in the upstream nerve junctions or in the brain, and it doesn't matter how "swift" the signal is from the acupuncture needle, so the explanation is nonsensical.

    5. Re:An apt reminder... by Anonymous Coward · · Score: 0

      You got it the wrong way. The way to *prove* an effect is by showing it distinguishable from chance. The problem with acupuncture is that it is hardto compare to a placebo (how can you fake to poke someone?) so there are no double blind studies available.

    6. Re:An apt reminder... by ChromeAeonium · · Score: 4, Interesting

      The skepticism will appear if you start saying "it matters where you stick the needles" and stuff like that.

      Apparently, there is at least one study that showed sticking them at random was actually better, or at least statistically the same, as the whole qi line thing. It is sad that this thing will be twisted and misrepresented by the alternative medicine quacks and used as a 'Nya nya we told ya so,' to skeptics who already suspected that the body does release pain killers when poked full of multiple small holes.

      When it comes to alternative medicine, pretty much any skeptic knows that there are three main ones which may have some merit (even if not enough to justify mainstream usage): chiropractic, because it actively affects the spine, naturopathy/herbal, because plants contain active ingredients, and acupuncture, because it actively affects the skin. What skeptics want is robust evidence indicating that these things work better that other traditional techniques, and those have simply not materialized, and until they do, color me skeptical about acupuncture as a whole, even if there is some method to the madness.

    7. Re:An apt reminder... by The+Leather+Duke · · Score: 3, Informative

      Only, this is not acupuncture. This is just piercing the skin with needles and then twisting them to see if you get a response. There are plenty of known methods through which that could operate.

      Acupuncture on the other hand supposes that the body has "meridians" and "acupuncture points" which you put needles into to manipulate the health of the body or parts of the body.

      To this notion I will still say that "there aren't any known methods through which it could operate."

    8. Re:An apt reminder... by hedwards · · Score: 1

      Sigh, acupuncture is more or less just a training system for this stuff. With enough study a person can do it completely on their own using just the power of their mind. The reason why they use needles is that it's really the only way that anybody has found to show people where those places that need stimulation are.

      The suggestion that this somehow makes acupuncture pseudoscience or not worthwhile is an idiotic conclusion to make. You don't hear people saying that sort of thing about Tylenol or most of the other OTC pain relievers even though they don't achieve even that level of result. Likewise we don't generally suggest that the education system needs to be tossed out because people are capable of learning completely on their own.

      But really on top of that, acupuncture just isn't something that lends itself easily to scientific study. I'm not defending the lack of definitive proof, but it is important to recognize that you're dealing with individuals who react in subtly different ways to treatment. And you can't readily separate out the sources of bias in the way that you would normally want to do. Which leads a lot of the studies to be more or less worthless in terms of giving a reliable conclusion.

    9. Re:An apt reminder... by Sique · · Score: 1

      There has been a large study (about 150,000 participants) about the effectiveness of acupuncture as a painkiller, and it came out quite positive for acupuncture vs. traditional painkillers. But as you mentioned -- poking anywhere on your skin without taking care of meridians and qi lines has about the same effect as following the acupuncture rules.

      --
      .sig: Sique *sigh*
    10. Re:An apt reminder... by rawtatoor · · Score: 1

      The magical thinking around chi alchemy is the result of Western charlatans taking what was effectively an 100% practial art and science and turned marketed it into a magical pill that heals all ills by next Tuesday. Protip: That ain't the way it works.

    11. Re:An apt reminder... by BiggerIsBetter · · Score: 2, Insightful

      I tried to explain to her the concepts of phase delays

      Note to the younger Slashdotters: Don't do this. The ladies really don't care.

      --
      Forget thrust, drag, lift and weight. Airplanes fly because of money.
    12. Re:An apt reminder... by noidentity · · Score: 1

      Yeah, the problem with plants is that there is also merit to putting random substance in your mouth, wherever it came from. Some subtances have beneficial effects, so you can't dismiss it. At this point I don't believe any claims made about all-natural from the garden of Eden plant substances unless there is a study I can read. I think most claims are just repeated from what they heard from yet another person, who was doing the same thing, or like those cellphone antenna booster stickers, from people who used the substance and either imaged beneficial effects, or attributed their improvement to the substance even though there were many other possible explanations.

    13. Re:An apt reminder... by Anonymous Coward · · Score: 0

      Citation? Was it randomized? What was the outcome measure used for effectiveness?

    14. Re:An apt reminder... by peragrin · · Score: 2, Interesting

      the thing is I have seen water divining work. The guy used a dowsing rod and found 4 wells for my neighbors, and 2 for my family. He even tracked the water from our neighbors well to our own. later geologists came through and mapped the entire area too. That old man was off by maybe 5%

      How it works i can't answer, but I did witness it working. He was wrong once, and with that, he as off by 10 feet in depth. (he said 20' and in reality it was 30')

      --
      i thought once I was found, but it was only a dream.
    15. Re:An apt reminder... by ChromeAeonium · · Score: 1

      Yep, the herbal thing is a strange animal because pharmacognosy, the study of medicines derived from plants, is a perfectly valid legitimate field of science, whereas chewing on a twig because it's natural is just kinda silly. It ticks me off a bit because (some) herbal medicine has real power, it really does, and for many centuries it was used to some degree of success, and is still used by many who can't afford drugs, and I hate seeing pre-scientific people slime such a beneficial field with their nonsense. I hear herbal medicine and automatically think quackery, and that's not right. What's funny is, if that twig is shown to produce a novel useful compound, and that compound is isolated, studied, synthesized, and administered in a measured does within a sugar pill it is called a pharmaceutical, and now the naturopaths say it is bad, and would rather have a random dose along with who knows what else. Weird people.

    16. Re:An apt reminder... by witherstaff · · Score: 1

      I got a trade of service years ago with a chiropractor, do web services for treatment. I'm now a believer in chiropractic services as part of good health. Not the 'Chiropratic is all you need' line of thought tho. This particular chiropractor uses the activator, basically a hand held device that gives little jabs. It's truly amazing to go in with a headcold, get a few little jabs, and instantly be able to breath clearly.

    17. Re:An apt reminder... by Joce640k · · Score: 3, Informative

      Water divining has been debunked many, many times. In randomized tests nobody can do it.

      http://video.google.com/videoplay?docid=7461912885649996034#
      http://www.youtube.com/watch?v=xOsCnX-TKIY

      Fast: You can dig almost anywhere on Earth and find water, it's just a question of depth (keep on digging there until it appears).

      --
      No sig today...
    18. Re:An apt reminder... by gad_zuki! · · Score: 1

      >...for those trying to defend the scientific method saying that a pseudoscience "cannot possibly work" because "there aren't any known methods through which it could operate".

      What? Skepticism isn't based on your little strawman. Its based on evidence. So, here's one study that was well thought out and well executed that might point to some kind of effect that isn't placebo. Great. Without this level of proof skepticism is 100% warranted, and is still warranted until we can see some replication of results. Studies from Chinese homeopathic researchers with no controls or that have been unreproducible are still junk science.

    19. Re:An apt reminder... by Anonymous Coward · · Score: 0

      Ever compress a pressure point to relieve the pain of a headache?

      Works for me so I don't have to take Ibuprofen. You call it placebo, I call it knowing the bodies proper reaction to directed stimulation to produce a desired result.

    20. Re:An apt reminder... by gslj · · Score: 1

      The magical thinking around chi alchemy is the result of Western charlatans taking what was effectively an 100% practial art and science and turned marketed it into a magical pill that heals all ills by next Tuesday. Protip: That ain't the way it works.

      I wouldn't say it was 100% "practical." When there are the same number of acupuncture points as there are days in the year, there's magical thinking going on. When a chi master is believed to be able to expel the chi force in his body and fly, there's magical thinking going on. Chi, mana, magical force, no difference. When the system of meridians is differentiated from the blood vessels only by the proportions of blood and chi in them (mostly chi, some blood flowing, vs. mostly blood, some chi flowing), even though blood vessels are easily discoverable in the body and the meridians are not, well, science is not at work.

      In a great many ways, Chinese traditional medicine is spookily similar to Western traditional medicine. There, too, health depends on the amount and proportion of a few essential fluids in the body. What the Chinese called qi flowing in meridians, the West called pneuma flowing in veins (until the experiments of Galen disproved that theory). There was a founder of medicine in both traditions (Yellow Emperor, Hippocrates), and Chinese herbal thinking had its counterpart in Western herbal medicine. (Compare the Shénnóng bnco jng to Dioscorides' Materia Medica).

      The more you look, the more similarities you see. The big difference is that the West turned its back on traditional medicine a bit over a hundred years ago, and it's largely been forgotten; in the East, it has been retained beside Western medicine, as a parallel system. Many people trust in both systems simultaneously...except for surgery. There is no such thing as "Chinese Traditional Surgery" being practiced.

      -Gareth

    21. Re:An apt reminder... by millennial · · Score: 1

      Then you're no longer talking about acupuncture; you're talking about methodical skin irritation. Acupuncture is, very specifically, a form of energy medicine centered around the idea of qi and meridians.

      --
      I am scientifically inaccurate.
    22. Re:An apt reminder... by millennial · · Score: 1

      Of course, that's patent nonsense. No amount of spinal adjustment will cure a head cold, which is congestion caused by blockage in the sinuses. More likely, you didn't have a cold, but an allergic swelling of the sinus that dissipated because you went indoors.

      --
      I am scientifically inaccurate.
    23. Re:An apt reminder... by mrmeval · · Score: 1

      Pseudo science is just that a fake. If there is a result to an act but we cannot explain it so what? Why do you need to spew some garbage to 'explain' it. Just define what is happening and test it until you have defined it's actions so you can go about applying it to real world problems. Hell we've done that with the transistor and so many other things. Who argues about how a water wheel works when it works? Later and in some cases centuries later we figure it out.

      I pissed of a Ufer nut who claimed that a ship had crashed and he'd been a government scientist driven mad trying to figure out how a device inside worked. I asked what the device looked like and what it did. Well it was something nutty but it had an interesting mechanical effect. I proceeded to describe a power generation system that would have powered the United States at it's current usage for however long these devices would have held up. The system was based on the described effects. They had to be booted and banned from chat after that as they had some sort of psychotic snap.

      --
      I'd go on a Vegan diet but the delivery time from Vega is too long. --brownkitty
    24. Re:An apt reminder... by Brian+Boitano · · Score: 1

      But doesn't acupuncture "mean": to stick with a needle?
      Soooo... yeah.

      --
      What would Brian Boitano do?
    25. Re:An apt reminder... by afabbro · · Score: 1

      ...for those trying to defend the scientific method saying that a pseudoscience "cannot possibly work" because "there aren't any known methods through which it could operate".

      The way to disprove a non-effect is by showing it indistinguishable from chance. Not by declaring that we can't think of any possible explanations.

      This is how we proved that the beating of tom-toms restored the sun after an eclipse.

      --
      Advice: on VPS providers
    26. Re:An apt reminder... by Anonymous Coward · · Score: 0

      To evaluate the correctness of a treatment you not only have to measure the result. You also have to show that the result is caused by the exact treatment.

      See, it is not the primary goal of the scientific method to disprove stuff you don't like. The goal is to get a better understanding of the world and use that to improve our methods.

      The difference between pseudo-science and real science is in my opinion that pseud-science is much quicker to settle with some explanation even without much investigation. When given the reasoning "A causes B" and you observer B then pseudo-science concludes that A must be true. A scientist wonders whether it was really A that caused B. We just can't assert every assumption made is true just because the conclusion is what we observed.

      If you put special needles into crossings of energy lines in your body that reduces pain. Following that procedure realy reduces pain. Pseudo-science concludes that there are energy lines and you have to put needles in them. A scientist asks what happens if you put the needles somewhere else, if you use other needles, if these energy lines are measurable in another way etc.

    27. Re:An apt reminder... by Anonymous Coward · · Score: 0

      To make that clear, you got a few little jabs with the result of being able to breath clearly. I can buy that. But that is very different from get a few little jabs and be cured.

      Like most medicin for a cold doesn't cure the cold. These medicines are usually not much more than pain killers and stimulant drugs that make you feel better.

    28. Re:An apt reminder... by noidentity · · Score: 1

      Who wants to be using mainstream cures? I'm an alternative type of person, and prefer the fringe! Even when it doesn't work and the mainstream stuff works great.

    29. Re:An apt reminder... by ChromeAeonium · · Score: 1

      I think that's exactly it. The key word in alternative medicine is not medicine. I think that if tomorrow homeopathy (or any other alt med, I pick on homeopathy because it is very popular and very dumb) were vindicated, some revolutionary new field of chemistry were discovered to support it, every study showing homeopathy bogus was shown to be the worlds largest statistical glitch, and homeopathy received approval by groups like the WHO, CDC, FDA, ect., we'd still see something emerge to challenge it. In a hundred years, people would be railing against homeopathy for the exact same reasons they now complain about science based medicines. Because in the end, this whole thing is just the materialization of social phenomenon, a reaction to something. I don't know what exactly...disdain for the popular and wanting to feel superior to others, or a fear that your health is in controlled by something you don't understand. Something, I don't know.

      It kind of reminds me of those kids in high school who always dissed popular music because it was popular, then disliked unpopular bands when others started liking them. I think alternative medicine guys are a lot like that. Except no one ever died from bad music.

    30. Re:An apt reminder... by The+Leather+Duke · · Score: 1

      If you're discussing etymology, then yes. But I was under the impression that this was about the "therapy" of sticking needles into specific points in the body.

      Not that etymology can't be used to muddle the topic. This is slashdot, after all.

    31. Re:An apt reminder... by chichilalescu · · Score: 1

      my mother is a medical doctor, and she also learned acupuncture some time after medical school.
      I felt acupuncture (actually, pressupuncture --- no needles, just finger poking) work on me.
      After more than 20 years experience of sometimes using acupuncture on her patients (she generally relies on what she learned in medschool), she says that there is stuff where acupuncture really works. She told me that she knows the "theory" is most likely bogus, but what she cares about is that if she follows the rules, good things happen to her patients.
      I do realize that with acupuncture there will be a lot of people who say it works for everything (my mother says it doesn't), just so that they can make more money.
      On the other hand, I also know that an animal is a very complicated physical system, and I wouldn't be surprised to find that there are still things we don't know about it (like for instance if someone pokes you with needles with the intent to heal, it actually heals you). I've heard of sick people swimming with dolphins and feeling better afterwards; I've also heard about people having different brainscans after swimming with dolphins.

      I think it's worth investigating (1) the exact level of control that the brain can exert on the body and (2) the full scope of possible interactions with the brain/nervous system. What if the whole "qi line" thing is just an average model of some superposition of minuscule coherent electromagnetic fields of the body that do interact with the nervous system in some way?

      Personally, I'm a physicist, and I know that with nonlinear systems, tiny fluctuations can do many things.

      --
      new sig
  7. Why is the placebo effect a bad thing? by sugapablo · · Score: 4, Interesting

    I'd much rather have a positive effect from a placebo than from a drug that usually has nasty side-effects.

    1. Re:Why is the placebo effect a bad thing? by Takichi · · Score: 4, Informative

      Except that you can not only get benefits, but also nasty side-effects from placebos.

    2. Re:Why is the placebo effect a bad thing? by arb+phd+slp · · Score: 2, Interesting

      I'd much rather have a positive effect from a placebo than from a drug that usually has nasty side-effects.

      I've wondered about this. If there is an actual placebo effect, we're drastically underutilizing it in the practice of medicine. As a result, there's a whole snake-oil industry overcharging for it and misleading people about it.

      --
      There's a perfect xkcd for my sig but I'm too lazy to look it up. sudo someone go find it.
    3. Re:Why is the placebo effect a bad thing? by xlation · · Score: 3, Insightful

      It's bad when Jenny McCarthy and Oprah use "success" from the placebo effect to cast doubt on science-based medicine. This doubt helps other scam artists sell expensive water to a patient who could be cured by real medicine.

    4. Re:Why is the placebo effect a bad thing? by Anonymous Coward · · Score: 0

      The nice things about actual drugs is, that you get the placebo effect for free to the real medicine. Real medication is always chemicals doing something in your body + placebo effect.

    5. Re:Why is the placebo effect a bad thing? by Anonymous Coward · · Score: 1, Informative

      But then it's not placebo, it's nocebo.

    6. Re:Why is the placebo effect a bad thing? by Scrameustache · · Score: 1

      I'd much rather have a positive effect from a placebo than from a drug that usually has nasty side-effects.

      I've wondered about this. If there is an actual placebo effect, we're drastically underutilizing it in the practice of medicine. As a result, there's a whole snake-oil industry overcharging for it and misleading people about it.

      Expensive placebos work better, and expensive wines taste better. Asking for more money is not overcharging, it's upping the placebo dosage :\

      --

      You can't take the sky from me...

    7. Re:Why is the placebo effect a bad thing? by hedwards · · Score: 1

      Hmm, you mean even ones like Tylenol that do basically nothing and run the risk of damaging the liver?

    8. Re:Why is the placebo effect a bad thing? by Ellie+K · · Score: 1

      I'd much rather have a positive effect from a placebo than from a drug that usually has nasty side-effects.

      All drugs do NOT have nasty side-effects. And despite my seeming post to the contrary above, about receiving acupuncture as pre-surgical anesthesia, I'd much rather receive traditional Western anesthesia for my next emergency appendectomy.

      --
      tempus fugit
    9. Re:Why is the placebo effect a bad thing? by Ellie+K · · Score: 1

      I'd much rather have a positive effect from a placebo than from a drug that usually has nasty side-effects.

      All drugs do NOT have nasty side-effects. And despite my seeming post to the contrary above, about receiving acupuncture as pre-surgical anesthesia, I'd much rather receive traditional Western anesthesia for my next emergency appendectomy.

      Actually many, or maybe all, drugs DO have nasty side effects, depending on circumstances, and at varying frequency rates. I'm ammending my prior comment. But often those rates are very, very low. I just don't take well to broad sweeping generalities. Spurious generalities? Or was that a Totse.darkbb-ism?

      --
      tempus fugit
    10. Re:Why is the placebo effect a bad thing? by Ellie+K · · Score: 3, Insightful

      Hmm, you mean even ones like Tylenol that do basically nothing and run the risk of damaging the liver?

      Uhh sorry, but NO, Tylenol is effective for fever and mild analgesia. It will wreak havoc on your liver if taken in excess, granted. But aspirin, ibuprofen (motrin and advil) will tear up your stomach lining if taken in excess. And analgesics like opiates have their own set of obvious drawbacks. Tradeoffs to all of them. Don't knock Tylenol. It's a bit wimpy, but with occasional usage tempered by common sense, it is effective. And it is NOT a placebo drug. WRONG.

      --
      tempus fugit
    11. Re:Why is the placebo effect a bad thing? by nospam007 · · Score: 1

      Better not to read about its worthlessness then, isn't it?

    12. Re:Why is the placebo effect a bad thing? by misexistentialist · · Score: 1

      Drugs that just alleviate symptoms are sort of like placebos. If reducing fever actually extended the duration of the disease and the number of days you were vomiting and coughing, you'd wish that you had only used acupuncture. Of course often the symptom might as well be the disease, so Tylenol would usually end up being a better cure than adjusting your primal energy flow.

    13. Re:Why is the placebo effect a bad thing? by jfengel · · Score: 1

      The placebo effect is real but less reliable than drugs. It does some good, but not all that much good, usually only a few percent.

      And they rely on your belief that they are real drugs. If you were a good medical consumer you'd research your drugs before taking them, and you'd run into "this is just a sugar pill" pretty fast.

      Every medical study controls for the placebo effect. If a drug doesn't work better than placebo, they don't sell it.

      Often, the placebo test is also used as a control for "no intervention at all". Often people get better without even so much as a placebo. The marginal benefit of the placebo, combined with the necessity for secrecy, means there's no point in giving you the actual placebo.

    14. Re:Why is the placebo effect a bad thing? by Anonymous Coward · · Score: 1, Informative

      Personally, i use acetaminophen (Tylenol)almost exclusively as a fever reducer, rather than as a general pain reliever.

      For that purpose, it is demonstrably effective. I can survive having protracted muscle aches. I can't survive a protracted 103F fever.

      For that reason I consider it (tylenol) a life saving drug.

      (granted, many different NSAIDs reduce fever; but the same methodologies through which you denounce tylenol as being only marginally effective (at pain relief) is also true with pretty much all NSAIDs. The real power of NSAIDs is not in relieving pain, but in reducing general inflammatory responses, and in treating fevers.)

    15. Re:Why is the placebo effect a bad thing? by Quiet_Desperation · · Score: 1

      I'd actually like to see more research done on the placebo effect itself. :-) Seems useful.

    16. Re:Why is the placebo effect a bad thing? by ameline · · Score: 1

      > Tylenol is effective for fever and mild analgesia.

      Key here being "mild". Acetaminophen, in my experience, has absolutely no noticeable effect on real pain. Opiates are pretty much the only thing in the pharmacopoeia that really work for this. All drawbacks aside, if you have real pain, those pale in comparison. (The worst of them, imho, is the constipation :-)

      (I recently had knee surgery involving drilling holes, hammers/chisels, screws & staples, and even 60mg Codeine did nothing in the first 48 hrs post op. Good thing there are stronger meds than that -- percosets ftw.)

      --
      Ian Ameline
    17. Re:Why is the placebo effect a bad thing? by osu-neko · · Score: 1

      Acetaminophen, in my experience, has absolutely no noticeable effect on real pain.

      Does it have a noticeable effect on anything? I've tried various different medicines over the years and finally learned to simply avoid anything that lists acetaminophen as an ingredient. As far as I can tell, it doesn't do anything at all. Nothing I've ever tried that contained it did me any good.

      --
      "Convictions are more dangerous enemies of truth than lies."
    18. Re:Why is the placebo effect a bad thing? by Chris+Burke · · Score: 1

      Oh well yeah, Tylenol isn't going to do anything for surgery pain. Real prescription-only painkillers then, please!

      But for common aches, pains, headaches, and fever, Tylenol can be effective. I wouldn't take Codeine for a twisted ankle, but I'll want something and acetaminophen helps.

      --

      The enemies of Democracy are
    19. Re:Why is the placebo effect a bad thing? by osu-neko · · Score: 1

      The placebo effect is real but less reliable than drugs. It does some good, but not all that much good, usually only a few percent.

      And they rely on your belief that they are real drugs. If you were a good medical consumer you'd research your drugs before taking them, and you'd run into "this is just a sugar pill" pretty fast.

      Every medical study controls for the placebo effect. If a drug doesn't work better than placebo, they don't sell it.

      Often, the placebo test is also used as a control for "no intervention at all". Often people get better without even so much as a placebo. The marginal benefit of the placebo, combined with the necessity for secrecy, means there's no point in giving you the actual placebo.

      Two problems here. First, it's not always true that it's "not all that much good". In fact, tests with placebos have shown them to be quite effective at times. Second, it's been demonstrated recently (I heard about this a few weeks back on NPR IIRC), that they don't necessarily rely in your belief that they are real drugs, that rather bizarrely they sometimes provide benefit even if the subject knows it's a placebo! So there may not necessarily be a "necessity for secrecy", although apparently it's helpful for there to be ambiguity. The NPR story talked with a doctor about possible ways to ethically use placebos in practice without lying to the patient about it. The method suggested was for a medicine where you take a pill every day or whatever time period, where sometime between the first and last pill, you've actually switched to sugar pills, but the patient doesn't know where the switch occurs. You can be perfectly honest with the patient, keep them from taking more medicine that might be healthy when it isn't necessary, and the pills continue to work until the end with greater effectiveness than taking nothing, even when it's gone into the pure sugar-pill stage.

      Anyhow, it was a very interesting segment.

      --
      "Convictions are more dangerous enemies of truth than lies."
    20. Re:Why is the placebo effect a bad thing? by jfengel · · Score: 1

      This is all correct; I was rather oversimplifying. (And felt like my post was too long even with that.)

      In fact, some drugs we do use today are no better than placebos. This is most notably true of antidepressants, which were developed for use in severe depression but do little in mildly depressed patients. When tested rigorously they do little better (or no better) than placebo, but the placebo effect is good enough to produce some good. This is known to the doctors and even some of the patients, but they find benefit in it anyway.

      Still, what I was really addressing was the widespread use of placebos, which I just don't expect to catch on. The placebos work in part against a background of drugs which do work, and if you were to introduce a cure-all panacea placebo I doubt it would do much good and might even hinder the ability of real drugs to achieve the placebo part of their effect.

    21. Re:Why is the placebo effect a bad thing? by millennial · · Score: 1

      Except... not at all. The drugs that alleviate symptoms are actually alleviating symptoms. There's chemistry at work there. They are nothing like placebos. Part of the placebo effect is the perceived alleviation of symptoms, as observed by a third party. The point of the placebo effect is that it's basically statistical noise that appears to be a real effect when seen in a specific individual. It isn't "mind over matter."

      --
      I am scientifically inaccurate.
  8. lol by Anonymous Coward · · Score: 0

    paw pain

    1. Re:lol by zygotic+mitosis · · Score: 0, Redundant

      Oh, won't somebody PLEASE think of the lab mice??

  9. Where's your pseudoscience now! by JamesP · · Score: 1, Flamebait

    Now that I have your attention bear with me...

    It's one thing to say "this is BS"

    It's another to say "we don't know how this may work, thus it doesn't mean that it works BUT IT ALSO DOESN'T MEAN IT DOESN'T"

    There are skeptics and there are "skeptics". "skeptics" make their first reaction to everything "this is BS"

    "Look, arteries may not have air inside them after all" "this is BS"
    "hey maybe interactions between charged particles can be abstracted by using 'a field'" "this is BS"

    It's ok to be skeptic, just keep your mind open before calling BS on everything. Good thing is these people never come up with a new theory or a new experiment usually.

    --
    how long until /. fixes commenting on Chrome?
    1. Re:Where's your pseudoscience now! by Spatial · · Score: 1

      This is BS.

    2. Re:Where's your pseudoscience now! by somersault · · Score: 1

      There are skeptics and there are "skeptics"

      This is BS!

      --
      which is totally what she said
    3. Re:Where's your pseudoscience now! by morgan_greywolf · · Score: 2, Informative

      Exactly. There are many things that like acupuncture that have been used medicinally for centuries. Just because we may not, at the time, understand any underlying mechanisms doesn't mean that they don't work; it just means that we don't understand the underlying mechanisms and therefore, have no proof that it works or does anything. But saying that is very different from saying that same thing doesn't work at all.

      For example, we didn't understand the underlying mechanism for aspirin until 1971, but before that salicylates had been used for centuries.

    4. Re:Where's your pseudoscience now! by JamesP · · Score: 1

      For example, we didn't understand the underlying mechanism for aspirin until 1971, but before that salicylates had been used for centuries.

      Exactly! Thank you!

      --
      how long until /. fixes commenting on Chrome?
    5. Re:Where's your pseudoscience now! by Virak · · Score: 0, Flamebait

      Ugh, there's another one of these a bit up, are we going to see a flood of stupid posts like these on this thread? Did you even read the rest of the summary, particularly the part about existing studies that conflict with this one? As it is, there's not a whole lot of research on acupuncture, and much of it appears to conflict each other. As a skeptic, my first reaction is indeed "this is BS"--as long as you don't have solid evidence for your claims. Guess what is not present here at all?

      If you're suddenly rushing to mock skeptics on the results of a single study, when there's plenty of existing studies that conflict with it, you either don't understand how this "science" thing works at all, or you don't really care about science and are just latching onto this to confirm your existing unfounded beliefs. Either way, you're in no position to make this sort of post. Having an open mind is good, so long as you take care to make sure it's not so open your brains start falling out.

    6. Re:Where's your pseudoscience now! by ascari · · Score: 3, Insightful

      And it's one thing to say "adenosine is released locally by needle pricks". And another to say that there are mysterious "meridians" that run through the body and connects your pinky toe to your heart, and your left butt cheek to your kidney or whatever, and that you can cure all kinds of diseases in those "connected" organs by poking the exactly right spots with needles.

      Yep, that's what at the root of accupuncture theory in TCM, not random pin poking. And this experiments doesn't even attempt to explain what's going on there. So while I'm absolutely not saying that TCM is wrong, I am saying that this experiment says very little if anything about traditional accupuncture the way it's been practiced for 4000 years. It's just a feeble attempt at quickly saying "this is NOT BS".

      So we still don't know how this works or indeed if it works, we only knows some mice produce adenosine locally under certain conditions. Accupuncture if it works as claimed would have to be much deeper, this hardly penetrates the surface. (Pardon the pun.)

    7. Re:Where's your pseudoscience now! by ChromeAeonium · · Score: 5, Insightful

      There are skeptics and there are "skeptics". "skeptics" make their first reaction to everything "this is BS"

      That's a load of crap. Skeptics make their first reaction to anything for which there is not sufficient evidence present "this is BS." That's a critical difference. As far as I know, acupuncture has not been exceptionally good at proving itself. It is based on the flow of some qi or whatever and claims to have all sorts of healing properties, neither of which have been proven in the least, and that is something to be rightfully skeptical about. If you make an extraordinary claim, I require extraordinary evidence. Plenty of new theories and ideas are accepted by skeptical types (for example, this was new, but there was no skeptic backlash, because it was a reasonable claim with reasonable evidence); just because some old time quackery is rejected doesn't mean skeptics are closed minded, that's just a way to distract form a lack of evidence. Medical skeptics have long admitted that minor injuries like sticking needles into yourself may trigger some pain-killer response, and this new thing, if indeed true, confirms that, not the validity of acupuncture. In fact, another study once showed that fake acupuncture outperformed 'real' acupuncture. It's not about simply denying everything, it is about denying everything until a reasonable amount of evidence exists to support it.

      You know, homeopathy used to 'work' too, back when mercury was a medicine, because it didn't do anything whereas medicine killed you, which may be why it is still around. Chiropractic, originally claimed to cure all sorts of things, has the same affects as a good massage. Do they get vindicated too now? Sometimes things get lucky, or traditions are held for some reason, and maybe acupuncture is one of them due to this effect, but there is still no reason to not be skeptical about redirecting your qi or whatnot, or its ability to outperform any modern science based pain killing methods (I'd go with a good hit o' weed myself, but that's a different debate). It's good to have an open mind, but not so open your brains fall out.

    8. Re:Where's your pseudoscience now! by grumbel · · Score: 4, Insightful

      There are many things that like acupuncture that have been used medicinally for centuries.

      Just because something is old, doesn't mean it works. There are plenty of old treatments that are either useless or even harmful. Which is why testing is the important part, you can't trust anecdotes, even if they have a long tradition.

      Just because we may not, at the time, understand any underlying mechanisms doesn't mean that they don't work;

      The issue isn't so much that we don't understand the underlying mechanism, but that we don't even have a clear indication that it works in the first place and you don't need to understand the workings of something to do the testing for its effectiveness.

    9. Re:Where's your pseudoscience now! by Virak · · Score: 2, Insightful

      This isn't even a problem of not understanding the mechanisms, it's a problem of not having solid evidence that it even works. Again, see the latter part of the summary which is about existing studies that have come to the conclusion that it doesn't work at all (is reading even the summary too much to ask for on Slashdot? I guess it is). "People have been using it since a very long time ago" is not proper evidence as to its efficacy. Bloodletting was in use for centuries too, by many different peoples; today, anyone with a basic education can point out many problems with it.

    10. Re:Where's your pseudoscience now! by JamesP · · Score: 2, Informative

      Did you even read the rest of the summary, particularly the part about existing studies that conflict with this one?

      So, what you're saying is that studies that contradict this one are more important?? That they should be taken more seriously, because everybody knows "acupunture is BS" right?!

      As it is, there's not a whole lot of research on acupuncture, and much of it appears to conflict each other.

      They usually don't, but it looks like that due to people exaggerating the scope of the conclusions.

      If you're suddenly rushing to mock skeptics ...you either don't understand how this "science" thing works at all,

      No, it's the "skeptics" that don't understand how this 'science' thing works. And worse, don't know squat about the history of science.

      As the example I gave in my post, most of the initial development of electromagnetism/electricity was called BS for a long time

      The discovery of Helicobacter pylori and appropriate treatment also was hampered by those 'skeptics'. But it's ok I'm sure only a few people died because of that.

      Also I'm sure not a lot of people died or got maimed because that thing called X-Ray is no good as a diagnosis help.

      Also, it's easier to come up with results that match previous WRONG results www.lhup.edu/~DSIMANEK/cargocul.htm (search Millikan)

      So yeah, I'm in no position to question that, sir because obviously I don't know anything about science or history of science...

      --
      how long until /. fixes commenting on Chrome?
    11. Re:Where's your pseudoscience now! by Virak · · Score: 1, Flamebait

      So, what you're saying is that studies that contradict this one are more important?? That they should be taken more seriously, because everybody knows "acupunture is BS" right?!

      I'm saying they're CONFLICTING , nothing more, nothing less. It means something's up with something, and unless you've got some method of deal with this conflict (with supporting evidence, of course), it's quite early to go "LOL ALL YOU 'SKEPTICS' SURE WERE WRONG HUH"

      So yeah, I'm in no position to question that, sir because obviously I don't know anything about science or history of science...

      Again, you are leaping to the conclusion that skepticism against acupuncture was unwarranted based on the results of a single study which conflicts with multiple existing studies. You most certainly do not know how science works. You don't just pick and choose studies and go "welp I like the results of this one more so it's way more important than the others".

    12. Re:Where's your pseudoscience now! by Antique+Geekmeister · · Score: 1

      There is a tremendous amount of research. Much of it is complete scientific balderdash, a few papers written on a few case studies without double blind technique or with very vague, interview based evaluation of the results. This is, sadly, very common in medical science.

      For an example, review this article on the famous "acupuncture appendectomy" during the Nixon administration.

    13. Re:Where's your pseudoscience now! by JamesP · · Score: 1

      I'm saying they're CONFLICTING , nothing more, nothing less. It means something's up with something, and unless you've got some method of deal with this conflict (with supporting evidence, of course), it's quite early to go "LOL ALL YOU 'SKEPTICS' SURE WERE WRONG HUH"

      Oh, ok. But as I said, the way to solve this conflicts is to look at the scope of the conclusion. Either that, or someone messed up.

      Now, I left something important out of my first post (yikes). The title is meant to be trollish and exaggerated. It's not a Nelson laugh!

      Again, you are leaping to the conclusion that skepticism against acupuncture was unwarranted based on the results of a single study which conflicts with multiple existing studies.

      Hum... No. Not unwarranted. But as this study shows you can always discover something new where many thought 'there was nothing there'. And that's the good thing about science.

      You most certainly do not know how science works. You don't just pick and choose studies and go "welp I like the results of this one more so it's way more important than the others".

      There's a field of studies called meta-analysis just for that. To see if they're picking only the studies they like.

      Funny how you think you know more about science and didn't provide examples or knew about meta-analysis

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    14. Re:Where's your pseudoscience now! by JamesP · · Score: 1

      There are skeptics and there are "skeptics". "skeptics" make their first reaction to everything "this is BS"

      That's a load of crap. Skeptics make their first reaction to anything for which there is not sufficient evidence present "this is BS." That's a critical difference.

      Problem n.1: Very few things have 'sufficient evidence' at first. That's the point of research. But then people go "there's not enough evidence so this is BS and I'm not going to research this" GOTO 10

      Problem n.2. Define "sufficient evidence". Sometimes "sufficient evidence" looks like "overwhelming evidence so I'm changing my opinion to save face"

      What I'm questioning is "calling BS" when the answer should be "let's research, wait for more tests before taking a stance". And I'm not even saying that about acupunture, but to lots of other things that had to "swim upstream" before being universally accepted.

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    15. Re:Where's your pseudoscience now! by Scrameustache · · Score: 2, Insightful

      Again, you are leaping to the conclusion that skepticism against acupuncture was unwarranted

      I don't think that's what he's doing. I think he's being ironic and you're missing out on it: He's saying 'skeptics' and '"skeptics"', and he's pointing out that the ones in double-quotes aren't really skeptical, they're really obtuse; they have decided that something is bullshit and nothing will ever make them stray from that position.

      His mistake was using subtle irony; On the net, that's sure to get you burned.

      His point is that skepticism is about having doubt, not certainty.

      --

      You can't take the sky from me...

    16. Re:Where's your pseudoscience now! by Scrameustache · · Score: 1

      There are skeptics and there are "skeptics". "skeptics" make their first reaction to everything "this is BS"

      That's a load of crap. Skeptics make their first reaction to anything for which there is not sufficient evidence present "this is BS." That's a critical difference.

      You missed the fact that he talks about skeptics and "skeptics". Notice the ". He put double-quotes to indicate irony, and that went right over your head.
      He was wrong to attempt subtle irony on the internet, that's a recipe for misunderstanding, but you were nonetheless wrong for missing his irony and flaming him for something you misunderstood.

      Now kiss and make up.

      --

      You can't take the sky from me...

    17. Re:Where's your pseudoscience now! by ChromeAeonium · · Score: 1

      Problem n.1: Very few things have 'sufficient evidence' at first. That's the point of research. But then people go "there's not enough evidence so this is BS and I'm not going to research this" GOTO 10

      Problem n.2. Define "sufficient evidence". Sometimes "sufficient evidence" looks like "overwhelming evidence so I'm changing my opinion to save face"

      Yeah, but they should at least have something going for them first. There are tons of new things being worked on. Those weren't simply chosen at random, people start working on those fields because there is some reason to think they will yield results. The sufficient evidence is either fitting with models or predictions or well reasoned hypotheses or early testing or something. And sure, there are things out there that don't have sufficient yet but are perfectly valid. Tomorrow we might discover that one radical new theory has been proven and all scientists that dismissed it will be looked at as chumps by people who don't get that they were just going by the evidence available to them at the time. Because, that available evidence is important.

      To paraphrase Sagan, 'They laughed at Einstein, ect., but they also laughed at Bozo' and there are a lot more Bozos than Einsteins, so it is preposterous to think that every stupid little thing should be investigated. Should we investigate homeopathy, even though it violates all known laws of biology, chemistry, and physics? How much more money should we spend debunking the Wakefield study? Should we test ear candling, reiki, reflexology, the Bates method, urine drinking, crystal therapy, ect.? Just because they're there? Of course not, it is not possible to research every possible possibility without some sort of good evidence. Acupuncture is the same way. After a while, with no indication that it works and many that it probably doesn't, it's time to call BS until something exceptional is found. Discovered qi or chakra or whatever flowing through the body? That's new, then it's time to reopen acupuncture. Got a well designed study indicating superior results? Same thing. But until then, no amount of accusations of being closed minded is a substitute for good proof.

    18. Re:Where's your pseudoscience now! by Virak · · Score: 1

      Oh, ok. But as I said, the way to solve this conflicts is to look at the scope of the conclusion. Either that, or someone messed up.

      The results of this paper are "acupuncture has a real mechanism and a real and measurable effect". The results of the other paper (along with other similar studies) are "there is no measurable difference in effect between real acupuncture and faked acupuncture". These can't both be true. "Someone messed up" is the obvious conclusion. And that's not even getting into the fact that supporters of acupuncture say it can do all sorts of insane things that this study couldn't even begin to explain.

      Hum... No. Not unwarranted. But as this study shows you can always discover something new where many thought 'there was nothing there'. And that's the good thing about science.

      The skeptics mentioned in the article aren't saying there's definitely "nothing there", just that this isn't good enough evidence. Even your hypothetical skeptics who say "this is BS" aren't saying there's definitely "nothing there". Calling bullshit on someone claiming a treatment works with no proposed method for it working and no proper evidence that it works is quite reasonable and far from completely and utterly denying the possibility that it could ever work.

      There's a field of studies called meta-analysis just for that. To see if they're picking only the studies they like.

      When I said "you", I meant you. There is no "they" involved here. And that's not even what meta-analysis is about. A meta-analysis is merely a study that examines and combines the results of multiple other studies on some matter, to provide a broader view of the available information. It's pretty much exactly as the name would imply it is. It has nothing to do with other people "picking only the studies they like". The only "picking studies" that goes on is in the meta-analysis itself.

      Funny how you think you know more about science and didn't provide examples or knew about meta-analysis

      Of course I knew about it, it's just wholly irrelevant to anything I've said. Funny how you think you know more about science and yet do not understand meta-analysis and think it applies to what I said.

    19. Re:Where's your pseudoscience now! by Virak · · Score: 1

      Yes, it's obvious that the double-quote "skeptics" are supposed to be what he sees as "idiots who irrationally deny it to the bitter end". The problem is that his conception of this appears to be equivalent to ordinary skeptics who are not irrational idiots, as though anyone who demands extraordinary evidence for extraordinary claims is just sticking their head in their sand. Though perhaps he just doesn't understand what people mean when they call something "bullshit".

    20. Re:Where's your pseudoscience now! by JamesP · · Score: 1

      To paraphrase Sagan, 'They laughed at Einstein, ect., but they also laughed at Bozo' and there are a lot more Bozos than Einsteins, so it is preposterous to think that every stupid little thing should be investigated.

      Oh, of course, It's not only a matter of 'may be interesting to investigate' but resources are limited, and grants are limited, etc. So yeah, we shouldn't investigate everything...

      Discovered qi or chakra or whatever flowing through the body? That's new, then it's time to reopen acupuncture. Got a well designed study indicating superior results? Same thing. But until then, no amount of accusations of being closed minded is a substitute for good proof.

      That's the idea! Cheers.

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    21. Re:Where's your pseudoscience now! by JamesP · · Score: 2, Insightful

      Oh, ok. But as I said, the way to solve this conflicts is to look at the scope of the conclusion. Either that, or someone messed up.

      The results of this paper are "acupuncture has a real mechanism and a real and measurable effect".

      No, the results of this paper are: "Inserting needles in rats triggers adenosine production in the area of needle insertion" (and you don't need to use a needle to stimulate adenosine)

      Do the other papers say "We inserted needles in rats and we measured adenosine and the nominal levels were found"??

      Well?

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    22. Re:Where's your pseudoscience now! by Belial6 · · Score: 1

      And it's one thing to say "adenosine is released locally by needle pricks". And another to say that there are mysterious "meridians" that run through the body and connects your pinky toe to your heart, and your left butt cheek to your kidney or whatever, and that you can cure all kinds of diseases in those "connected" organs by poking the exactly right spots with needles.

      And it's one thing to say "adenosine is released locally by needle pricks". And another to say that there are mysterious "meridians" that run through the body and connects your pinky toe to your heart, and your left butt cheek to your kidney or whatever, and that you can cure all kinds of diseases in those "connected" organs by poking the exactly right spots with needles.

      That's part of the problem. It really isn't. We know scientifically that there are lines through the body that connect parts of the body. We call them nerves. One of the big problems is that when someone sees an effect, they try to find an explanation. Sometimes the explanation is that the effect is from wishful thinking, sometimes it is that they only think there was an effect, sometimes the explanation is a good rational guess.

      When there is a real effect, and it isn't from a placebo, the scientific method is a reliable way to determine why the effect happens. Even so, for a real effect, making up a bogus reason does not change the effect. This means that experiments, and even the scientific method can produce results confirming magic. Case in point, if I set up a proper experiment to test whether I can attract microscopic fire sprites to my hands by rubbing them together really fast. I can set up controls, and do all of the good science to test it. I can predict the heating of my hands from the fire sprites, and show that in fact fire sprites ARE attracted to my rubbing hands. I would still be wrong of course, but I would have an experiment that 'proved' fire sprites. The fact that I was wrong as to why would not make rubbing my hands together on a cold day any less effective at warming them.

      The whole thing gets worse when you claim a thousand different effects caused by an action, and argue it with a thousand different people.

      The fact is, we KNOW that sticking needles in peoples body will produce a reaction. The question is whether it produces an good reactions, and if it does, what those reactions really are. As individuals, we need to do a risk analysis on the quantity/likelyhood/quality of the good reactions to the quantity/likelyhood/quality of the bad reactions. This includes the bad reaction of cost.

    23. Re:Where's your pseudoscience now! by Virak · · Score: 1

      Well that's the "real mechanism" part. As for the "measurable effect", please see figure 3 of the paper. They used an injection to cause inflammation and then tested the response of the mice to touch and heat, showing both increased sensitivity after injection and a return to lower levels of sensitivity after their acupuncture, with mice without the receptors that would cause the adenosine to be produced having no such reduction.

      The results of this paper are exactly as I said. To quote the paper itself, "These findings suggest that A1 receptor activation is both necessary and sufficient for the clinical benefits of acupunctures."

    24. Re:Where's your pseudoscience now! by JamesP · · Score: 1

      Thanks for the link.

      Well, at least this is Nature (as opposed to 'magazine for people that need to publish an article or else no grant money'), people will start examining their claims now (as it should be)...

      The results of this paper are exactly as I said. To quote the paper itself, "These findings suggest that A1 receptor activation is both necessary and sufficient for the clinical benefits of acupunctures."

      Well, you're right. But that's the conclusion they've drawn. The authors may be exaggerating a bit (for visibility reasons).

      If they had said "inserting needles" instead of acupuncture we probably wouldn't be having this conversation. And in the end it doesn't matter.

      Does this validate qi, channels through the body, or whatever about acupunture? NO! So even if this work gets validated, that doesn't validate acupunture either!

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    25. Re:Where's your pseudoscience now! by Scrameustache · · Score: 1

      as though anyone who demands extraordinary evidence for extraordinary claims is just sticking their head in their sand. Though perhaps he just doesn't understand what people mean when they call something "bullshit".

      I think he's talking about the ones who demand extraordinary proof for ordinary claims. There's people out there who just call things "bullshit" reflexively and they won't ever admit they're wrong, even as you show them more and more proof they just continue to pretend to be skeptics, but they aren't being cautious or critical: they just don't want to accept facts that contradict their established beliefs. And they call themselves skeptics, so we have reasons to be skeptical of the actual skeptical nature of self-described skeptics.

      So there's people who irrationally believe things, and people who irrationally believe the contrary, and the second group likes to think of themselves as skeptics. Which they aren't, not really. But doing so reinforces their disbelief.

      --

      You can't take the sky from me...

    26. Re:Where's your pseudoscience now! by The_mad_linguist · · Score: 1

      "There are many things that like acupuncture that have been used medicinally for centuries."

      Like mercury.

    27. Re:Where's your pseudoscience now! by osu-neko · · Score: 1

      It's another to say "we don't know how this may work, thus it doesn't mean that it works BUT IT ALSO DOESN'T MEAN IT DOESN'T"

      And it's quite another thing to say "we know how this works, it works by disrupting the flow of your chi along the longitudinal meridians of your skin when the moon is full".

      The fact that pseudoscience works doesn't alter the fact that it's BS.

      --
      "Convictions are more dangerous enemies of truth than lies."
    28. Re:Where's your pseudoscience now! by morgan_greywolf · · Score: 1

      Just because something is old, doesn't mean it works.

      No, but if something doesn't work at all, it is far less likely to be used for very long. Why has Unix been so pervasive for the last 40 years?

    29. Re:Where's your pseudoscience now! by morgan_greywolf · · Score: 1

      This isn't even a problem of not understanding the mechanisms, it's a problem of not having solid evidence that it even works.

      I read the short-sighted, biased summary, yes. My comment contradicts it specifically because I don't agree with it. Aren't we all entitled to our own opinion, or do you think we should take whatever is written in the fine summary or the fine article as gospel truth?

      And bloodletting is still commonly used to treat disorders such as hemochromatosis. Leeches and maggots are also still used to treat some kinds of infections due to open wounds and such.

    30. Re:Where's your pseudoscience now! by JamesP · · Score: 1

      Exactly! Thank you!

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    31. Re:Where's your pseudoscience now! by Chris+Burke · · Score: 1

      Exactly. There are many things that like acupuncture that have been used medicinally for centuries. Just because we may not, at the time, understand any underlying mechanisms doesn't mean that they don't work.

      Except acupuncturists claim to have a mechanism. It's integral to properly practicing acupuncture and to achieving the effects they claim which go well beyond simple pain relief.

      Traditional medicine often has some basis in reality, but it varies how closely the actual practice is connected to that reality. Traditional medicine unsurprisingly gets encumbered by tradition, and with it comes both rules and results that don't matter and don't happen, respectively. It's understandable how this happened long before the existence of concepts like "confirmation bias". You put the needles in the way you were always taught to put the needles, your patients get better sometimes, and hey two days after treatment your neighbor passed that kidney stone.

      Which is why I'm all for studying all of these traditions with science. We can find the part of it that really works, and discard the parts that were because nobody bothered with double-blind studies back then.

      Bloodletting and leeches like you mentioned in another post are actually perfect examples. Finding them useful for some things doesn't equate to validating all the other uses they were put to. Research was done, they figured out that hey leeches are actually helpful for keeping a wound clean and preventing coagulation, and there you go. The real benefit, minus a bunch of illogical and unhelpful crap.

      Heck, people thought they saw enough therapeutic benefit from using quicksilver that they kept prescribing that.

      If the results of this study carry over to humans, then it could mean that acupuncture does really work for pain relief by stimulating the release of natural anesthetics. Which is great. But it doesn't seem to matter where you put the needles, the mechanism doesn't suggest anything beyond temporary pain relief, and the greater claims of acupuncturists have yet to pan out after investigation.

      --

      The enemies of Democracy are
    32. Re:Where's your pseudoscience now! by cheesybagel · · Score: 1

      My guess is you never had acupuncture. Sure I do not believe a lot of the quackery it is sometimes used for. However it does work for treating and managing pain. I have back pain and it took away the pain, in a way pain killers did not. Not to mention that it has a lasting effect, in a way pain killers do not. I also know several people who had the same experience. I have also noticed the people who do acupuncture properly actually know where you hurt the most (even if you do not explicitly tell them) and treat that area more. While if I go to the doctor he can only tell where I have a problem by doing loads of finger pressure, plus hearing me say "ouch" or by doing scans.

    33. Re:Where's your pseudoscience now! by JimBobJoe · · Score: 1

      I'd go with a good hit o' weed myself

      Now that's an interesting way of livening up my next acupuncture session.

    34. Re:Where's your pseudoscience now! by mjwx · · Score: 1

      There are skeptics and there are "skeptics".

      What you call "Scepticism" is more commonly refereed to as being in denial.

      Being sceptical means that you want proof, you haven't got enough information to make a decision, this in general is a good thing.

      Being in denial means that you've made a decision and are using whatever evidence you can to justify that decision. This is not a good thing at all.

      --
      Calling someone a "hater" only means you can not rationally rebut their argument.
  10. Paw discomfort! by seyyah · · Score: 4, Funny

    Dr. Maiken Nedergaard of the University of Rochester Medical Center and her colleagues administered half-hour acupuncture treatments to a group of mice with paw discomfort.

    Family-friendly euphemism for "with their paws hacked off by the grad students".

    1. Re:Paw discomfort! by drinkypoo · · Score: 0, Offtopic

      Dr. Maiken Nedergaard of the University of Rochester Medical Center and her colleagues administered half-hour acupuncture treatments to a group of mice with paw discomfort.

      Family-friendly euphemism for "with their paws hacked off by the grad students".

      Actually, they crucified the mice on Popsicle-stick crosses.

      --
      "You're right," Fisheye says. "I should have set it on 'whip' or 'chop.'"
  11. My Brain Pain Increased by Two-Thirds ... by foobsr · · Score: 2, Insightful
    after wondering how they measure

    mice with normal adenosine function experienced a two-thirds drop in paw pain

    CC.

    --
    TaijiQuan (Huang, 5 loosenings)
    1. Re:My Brain Pain Increased by Two-Thirds ... by elewton · · Score: 3, Funny

      Tiny, mousey emoticons.

    2. Re:My Brain Pain Increased by Two-Thirds ... by Thanshin · · Score: 2, Informative

      after wondering how they measure

      "mice with normal adenosine function experienced a two-thirds drop in paw pain"

      By facial expression.

      http://www.google.fr/search?hl=fr&q=facial+expression+mice+pain+&meta=

    3. Re:My Brain Pain Increased by Two-Thirds ... by NekSnappa · · Score: 1

      Watching how they walk immediately after treatment would show if there was an effect. Now how they quantify it I don't know.

      --
      I want to shoot the messenger!
    4. Re:My Brain Pain Increased by Two-Thirds ... by Scytheford · · Score: 1

      As much as I would like to believe this, I think the truth would be closer to measuring levels of stress hormones before and after.

    5. Re:My Brain Pain Increased by Two-Thirds ... by phantomcircuit · · Score: 1

      By facial expression.

      http://www.google.fr/search?hl=fr&q=facial+expression+mice+pain+&meta=

      It's a phishing attack!! Everybody knows google is in AMERICA! Crazy frenchy.

      :P

    6. Re:My Brain Pain Increased by Two-Thirds ... by Reziac · · Score: 1

      It's judged by measuring neurological response in the brain. Essentially hook a meter to the right part of the brain and squeeze a toe at a given pressure level. Watch the meter and judge how much response the brain is making.

      I vaguely recall that some similar setup was used a while back during research to gauge effectiveness of human anaesthesia during surgery (due to the problem of some patients "waking up" in mid-operation).

      --
      ~REZ~ #43301. Who'd fake being me anyway?
    7. Re:My Brain Pain Increased by Two-Thirds ... by Chris+Burke · · Score: 1

      It's a phishing attack!! Everybody knows google is in AMERICA! Crazy frenchy.

      Ah, but you have to go to Google France in order to get the link to the French study. In that one, they didn't cause discomfort in the mice by hurting their paws, but rather by offering a boring and pedestrian selection of cheeses.

      --

      The enemies of Democracy are
    8. Re:My Brain Pain Increased by Two-Thirds ... by Anonymous Coward · · Score: 0

      C'est l'attaque la pêche, vous insensible Claude!

    9. Re:My Brain Pain Increased by Two-Thirds ... by Thanshin · · Score: 1

      C'est l'attaque la pêche, vous insensible Claude!

      Brilliant.

  12. It's not a bug it's a feature! by Xenna · · Score: 4, Insightful

    Hah, but that's the paradox!

    You can't have a placebo-effect unless you claim that the therapy actually works in itself.
    You can't claim that a non-working therapy works unless you a a liar.
    The placebo effect works better if the treatment is costly (in terms of money or discomfort - pain from needles)

    So the placebo industry can only exist if they mislead and overcharge.
    It's not a bug it's a feature!

    X.

    1. Re:It's not a bug it's a feature! by hedwards · · Score: 1

      It's not, you just don't call it a placebo when the person knows about it. It's a relatively common way of treating things like migraines, back pain, explosive temper and a large number of mental illnesses. It's a misconception that to make use of that effect that you can't know about it, you just don't call it a placebo when you're doing it purposely. It's sort of like why hypnosis does such a great job for pain relief even though it tends to do a lousy job of treating other things.

    2. Re:It's not a bug it's a feature! by TheLink · · Score: 1

      > You can't have a placebo-effect unless you claim that the therapy actually works in itself.
      > You can't claim that a non-working therapy works unless you a a liar.

      You miss the point. For many conditions a placebo is not a nonworking therapy. So if it works you're not a liar. And placebo treatments do work 30-40% of the time for certain problems. You're only a liar if you make claims about the treatment that aren't true.

      Many drugs/procedures only work well for some people and some cases.

      So for a noncritical condition where a placebo has 30-40% chance of working with a low chance of side effects, vs a drug that has 50% chance of working and a higher chance of bad side effects, a doctor might choose to prescribe a placebo and ask the patient to come back after a few days to see how well it works. The doctor does not have to lie. Of course if the patient asks for the name of the drug the doctor might then have a problem. Many religious people may not even need to see a doctor to tap the placebo effect. The atheists on the other hand might find it hard to ask and get help from the FSM ;).

      The drug companies probably hate the placebo effect - a fair number of their candidate drugs can barely beat it in trials :).

      --
    3. Re:It's not a bug it's a feature! by nullchar · · Score: 1

      That's exactly what Xenna said: you must claim that the therapy works in order to have the placebo effect.

      If the acupuncturist said, "What I'm about to perform with these needles won't directly cause you pain relief (and I may not even prick your skin), but as long as you believe it works you may feel better", they might not get a lot of repeat customers.

    4. Re:It's not a bug it's a feature! by Xenna · · Score: 1

      > You can't have a placebo-effect unless you claim that the therapy actually works in itself.
      > You can't claim that a non-working therapy works unless you a a liar.

      You miss the point. For many conditions a placebo is not a nonworking therapy. So if it works you're not a liar. And placebo treatments do work 30-40% of the time for certain problems. You're only a liar if you make claims about the treatment that aren't true.

      Mmm, yes, that's exactly my point. Thank you for pointing that out ;)

      The drug companies probably hate the placebo effect - a fair number of their candidate drugs can barely beat it in trials :).

      Again you seem to mean the opposite. If the drugs aren't doing better than placebo's, they are placebo's!

    5. Re:It's not a bug it's a feature! by thoughtfulbloke · · Score: 1

      There are informed consent ways of delivering placebos.

      In the case of a study with patients with an anxiety disorder they were basically told "We would like to prescribe you this treatment with no medical benefit which has been found to be effective in cases like yours". It still worked.

      It was cited in Ben Goldacre's book Bad Science (which I don't have immediately to hand for the full reference).

    6. Re:It's not a bug it's a feature! by TheLink · · Score: 1

      No. You really don't get it.

      Most medical drugs and treatments don't work 100% of the time. That does not mean they don't work. And they are not the same as "no treatment".

      Similarly placebos don't work 100% of the time. That does not mean they don't work. And they are not the same as "no treatment".

      If you look at many proper studies of drugs and treatments you can see there are differences in outcome of the drug, the placebo and "no treatment".

      > If the drugs aren't doing better than placebo's, they are placebo's!

      Not necessarily. In theory you could have a treatment/drug that works in say 20% of the cases, worse than placebo, but it still works about the same even if you tell the patient it's a sham treatment, or the patient is unaware/unconscious when you apply the treatment/drug.

      --
    7. Re:It's not a bug it's a feature! by The_Noid · · Score: 1

      No. You really don't get it.

      Most medical drugs and treatments don't work 100% of the time. That does not mean they don't work. And they are not the same as "no treatment".

      Similarly placebos don't work 100% of the time. That does not mean they don't work. And they are not the same as "no treatment".

      No, placebo's NEVER work, that's the definition of a placebo. The reason the placebo seems to work is because of the psychological effect of "being treated". The placebo effect is not caused by the placebo itself!

      > If the drugs aren't doing better than placebo's, they are placebo's!

      Not necessarily. In theory you could have a treatment/drug that works in say 20% of the cases, worse than placebo, but it still works about the same even if you tell the patient it's a sham treatment, or the patient is unaware/unconscious when you apply the treatment/drug.

      Again, no. If a drug works in 20% of the cases, it would show a 20% increase over the placebo effect.

      Lets look at the statistics for a drug that works in 20% of the cases, with a group of test subjects that has a placebo effect in 30% of the cases:
      In the control group 30% of the patients would feel better because of the feeling of being treated (which is the placebo effect). In the test group, the same 30% of the patients would experience the placebo effect. Of this 30%, 20% would additionally have a real effect, but it might be impossible to differentiate.
      Of the 70% not experiencing placebo effect 20% would have a real effect, leading to a total of 44% feeling an effect.

      To sum it up:

      Control group:
      30% placebo effect
      70% no effect

      Test group:
      24% pure placebo effect
      6% combined placebo/drug effect
      14% pure drug effect
      56% no effect

      If a drug does not show an effect above the placebo effect, it is a placebo.

  13. They have video of the grad students' work by NotSoHeavyD3 · · Score: 0, Offtopic
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  14. Acupuncture cult pseudo-science by vorlich · · Score: 0, Flamebait

    Acupuncture gained its present foothold in the subconscious of fools shortly after Mao took over China in 1949. The Communist party of China had promised everyone health care, but were in fact unable to deliver proper science-based medicine to the vast population. "Bicycle Doctors" were encouraged to promote herbal and traditional Chinese medical treatments to save money and hide the absence of proper drugs.

    Not only did this let a thousand flowers of nonsense bloom and condemn thousands of Brown Bile Bears to inhumane torture, it also convinced gullible Western visitors that the Chinese had some miraculous medical treatments unknown and unexplained by modern science. Pretty much like the gullible Western visitors who went to the Soviet Union shortly after the revolution and declared that they had been to the future and it worked. This research is just another example of flying-saucer-science intended to sucker people into believing that paying out heaps of money for snake-oil is a good idea.

    So just to be clear: acupuncture is a cult, a pseudo-science without basis in fact, just like its home companions homeopathy, yoga and Reiki.

    I'm not going to provide links since the muppets who reply to say that their great grandmothers survived World War One and Two, smoked liked a chimney, drank like a fish, had unprotected sex with 9 thousand partners, consumed vast quantities of lard, fast food and chips, never ate fruit and attributed their excellent health to homeopathy, acupuncture and Reiki, will do those for you.

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    1. Re:Acupuncture cult pseudo-science by Scrameustache · · Score: 1

      So just to be clear: acupuncture is a cult, a pseudo-science without basis in fact, just like its home companions homeopathy, yoga and Reiki.

      Ah! You think Yoga has no basis in fact? There's some very toned and flexible hotties out there proving you wrong.

      --

      You can't take the sky from me...

    2. Re:Acupuncture cult pseudo-science by Admiralbumblebee · · Score: 1

      How is yoga a pseudoscience? I was not aware there was even any attempted 'science' aspect to it at all, and my family is very active in yoga practices. Perhaps there are cultish groups that use and promote yoga, but unless I'm missing something very major yoga itself is not a pseudoscience.

    3. Re:Acupuncture cult pseudo-science by Abcd1234 · · Score: 2, Insightful

      Ah! You think Yoga has no basis in fact? There's some very toned and flexible hotties out there proving you wrong.

      Well, ridiculous health claims (eg, treating autoimmune disorders, etc) associated with yoga are pseudo-science.

      Similarly:

      Chiropractic care for the treatment of back issues? Fact. Chiropractic care for the treatment of asthma? Pseudo-science.
      Homeopathic treatment of dehydration? Fact. Homeopathic treatment of basically anything else? Pseudo-science.

    4. Re:Acupuncture cult pseudo-science by Zerth · · Score: 1

      Ah! You think Yoga has no basis in fact? There's some very toned and flexible hotties out there proving you wrong.

      Um... This is slashdot, after all.

    5. Re:Acupuncture cult pseudo-science by rtorlas · · Score: 1

      I don't especially care to be called a fool. I was dragged to an acupuncturist by my wife. I had no doubts that it was a waste of time and money. However, I walked out of there pain free for the first time in 10 years. I don't care what skeptics think. I don't care what the mechanism is. I just know in my case it worked and am thankful for it.

    6. Re:Acupuncture cult pseudo-science by Anonymous Coward · · Score: 0

      Do you honestly believe that something that people have been using for centuries would have no positive effect at all?

    7. Re:Acupuncture cult pseudo-science by rtorlas · · Score: 1

      BTW, I had been to many, many traditional doctors who couldn't even diagnose the cause much less provide any relief. None of the drugs they gave me helped at all.

    8. Re:Acupuncture cult pseudo-science by Anonymous Coward · · Score: 0

      Chiropractic care for asthma when your asthma is caused by pressure and irritation to the lungs based on your crooked ass posture: Fact.

      Not that I ever had asthma officially, I just had a few symptoms before I went to the chiropractor to fix my back after a car accident. He re-aligned my spine and mentioned that my posture from the way I sit in front of a computer had altered my spine in a way that was making it hard to breathe. About 6 weeks of twice a week treatment made a world of difference. So in short, yes. Chiropractic care to enable you to breathe deeper would probably be a helpful treatment for an asthmatic. Not the cure, or even the only treatment by a long shot, but definitely a quality of life treatment

    9. Re:Acupuncture cult pseudo-science by Scrameustache · · Score: 1

      Ah! You think Yoga has no basis in fact? There's some very toned and flexible hotties out there proving you wrong.

      Well, ridiculous health claims (eg, treating autoimmune disorders, etc) associated with yoga are pseudo-science.

      Ok, yes, there's True Believers that will tell you yoga cures cancer, feeds the poor and plugs the gulf of mexico's oil hole. But there is significant merit in the practice of Yoga for health benefits, even if it doesn't protect us from asteroid strikes.

      --

      You can't take the sky from me...

    10. Re:Acupuncture cult pseudo-science by Abcd1234 · · Score: 3, Informative

      Chiropractic care for asthma when your asthma is caused by pressure and irritation to the lungs based on your crooked ass posture: Fact.

      No, it's not. It's bullshit. Show me a single study that proves chiropractic care treats asthma, and I'll show you a flawed study.

      And as an aside, anyone who believes "asthma is caused by pressure and irritation to the lungs based on your crooked ass posture" has no fucking clue what asthma actually is.

      Not that I ever had asthma officially

      Ah. I see. So you feel you can make concrete statements about asthma treatment when you've never actually been diagnosed with it. Well, I'll definitely take your opinions seriously...

    11. Re:Acupuncture cult pseudo-science by Scrameustache · · Score: 1

      Ah! You think Yoga has no basis in fact? There's some very toned and flexible hotties out there proving you wrong.

      Um... This is slashdot, after all.

      Touché.

      --

      You can't take the sky from me...

    12. Re:Acupuncture cult pseudo-science by Abcd1234 · · Score: 1

      And now, because we understand the mechanism of action upon which acupuncture is based, scientists may be able to develop more effective treatments, either by optimizing acupuncture treatment, or creating new treatments that make use of the same mechanism.

      You should be thanking science, here. We now understand more about the world than we did before, and the result may be improved medicine for people such as yourself.

    13. Re:Acupuncture cult pseudo-science by Anonymous Coward · · Score: 0

      Hey, don't talk about my mom that way! She did eat fruit!

    14. Re:Acupuncture cult pseudo-science by Anonymous Coward · · Score: 0

      Cutters. Pokers. Nothing new here.

    15. Re:Acupuncture cult pseudo-science by Anonymous Coward · · Score: 0

      Any Chiro that claims they can cure any illness or disorder from spinal adjustments is a crook.
      Reflexology though thats the stuff! *cough*

    16. Re:Acupuncture cult pseudo-science by Anonymous Coward · · Score: 0

      You must know a lot more than our current scientific understanding of the immune system to know that such things are pseudo-science.

  15. how dare they? by Anonymous Coward · · Score: 0

    how dare slashdot support such a dirt, nasty habit as intravenous drug use??? Prescription abuse is much safer! Now, where is my vicodin/morphine combo?

  16. Do you honestly believe that something that has be by Anonymous Coward · · Score: 0

    Do you honestly believe that something that has been used for thousands of years would have no positive effect at all?

  17. The problem is that every person is unique by nido · · Score: 1, Informative

    Similar pains in different people are triggered by different energetic imbalances. Oriental medicine has five elements, five rhythms that run through a person: Water, Wood, Fire, Earth, Metal (Air). Each meridian has characteristics of one of the elements.

    But westerners who study acupuncture try to use the same points in their trials, when the study should be designed to address the individual's specific imbalances.

    I've met a few mystics in the last few years, and my experience says that people who "scoff" at the notion that acupuncture is quackery are idiots. YMMV.

    --
    Learn the rules so you know how to break them properly.
    www.teslabox.com
    1. Re:The problem is that every person is unique by Anonymous Coward · · Score: 0

      Similar pains in different people are triggered by different energetic imbalances. Oriental medicine has five elements, five rhythms that run through a person: Water, Wood, Fire, Earth, Metal (Air). Each meridian has characteristics of one of the elements.

      But westerners who study acupuncture try to use the same points in their trials, when the study should be designed to address the individual's specific imbalances.

      I've met a few mystics in the last few years, and my experience says that people who "scoff" at the notion that acupuncture is quackery are idiots. YMMV.

      Your post seems to be the most reasonable of all the close-minded hot air huffers posting here. I, myself, have been a patient undergoing Acupuncture from a very skilled and amazingly interactive doctor. She was able to restore feeling to my left leg and foot that before had been so numb I could barely feel it.
      During the treatments, with the needles in place, I could feel what was happening inside my body, tell her, and she would make adjustments to the needles to compensate. The Qi as they call it, is actually the tiny electromagnetic/ electrostatic fields produced by the cells of our bodies that work together to create our individual EM/ ES fields that change second to second but have a balance to them when we are in good health. The needles, in their proper places according to the individuals' needs, can be tuned we found. Evidently, not everyone has the sensitivity to notice this, as my doctor was surprised at the level of feedback I was able to give her. When the needles in my left and right legs were rotated slowly, I could feel the same kind of electric "communication" between them as I have felt between the electrodes on a TENS unit. It was amazing. I could also feel other needles "communicating" with each other as well.

      Acupuncture may be overstated in what it can cure, or what some can do with it. Also, I'm sure it is plagued with people who practice it who have no clue what they are doing. And, I believe it is less successful for those who do not know how to listen to their bodies because the Acupuncturist has to actually seek out and map out your individual points.
        But, it is real. It does have real applications, and it can not only reduce pain but, as in my case, give you back the full use of your left leg and foot. Which isn't absolutely a great thing in a way as I have a bad case of Fibromyalgia, and now that I can actually feel my left leg and foot I can also feel the bloody pain that courses through them non-stop...lol. But, at least they are there now.

    2. Re:The problem is that every person is unique by cheesybagel · · Score: 1
      People scoff at the five elements quackery because we used to have a similar concept in European medicine dating from Greek and Roman times. Bloodletting, and primitive blood transfusions, were based on the concept of balancing "humors". The four humors as defined by Galen were: blood, phlegm, black bile, yellow bile. This "theory" dominated Western medicine until around the Renaissance when it was thoroughly discredited.

      I do have a personal experience of acupuncture working for chronic pain. However I dispute some of the more fantastic claims of wondrous cures using acupuncture. There is a reason why the introduction of European medicine revolutionized Asian medicine and culture. Because it actually worked in a predictable fashion in a lot of cases where Asian medicine did not.

  18. Acupuncture by rawtatoor · · Score: 1, Troll

    I compare acupuncture and qigong to time travel. Imagine if you were a time traveler and you wanted to convince someone who never *directly experienced* it that it was real. It isn't possible. The only way is to feel it yourself.

    Acupuncture is based on lines of tendons and fascia "meridians" connecting between extremities and organs. Now "chi" at it's simplest level is nothing more than stimulating certain groups of nerves at will. And chigong is studying your internal alchemy to differentiate between the many different plexuses of nerves. For example I can concentrate on the arch of my foot up the inside of my thigh and stimulate my kidneys and adrenals. Tell me it's psuedoscience, so what? It's real to me. You just kind of have to shrug at skeptics, because they refuse to experience they can never be "convinced".

    The book that really made it click for me was ironically a Qigong for Women book I think by Ferraro. But the teachers with the most complete work are Mantak Chia (internal) and Yang Jwing-Ming (external). Any book by either of those two will teach you the true science of chi, but you have to experience it for it to mean anything. All I'll say is they cure cancer with qigong, search for the studies its real; and if I got cancer I wouldn't be poisoning myself with radiation I'd be doing kungfu.

  19. Re:Do you honestly believe that something that has by dstar · · Score: 1

    Um... yes?

    Many things have been used for thousands of years. Many of those things have no positive effect. Many of *those* things are actively harmful.

    You sound like a woman my wife had an argument with a decade or so ago, who insisted it was perfectly safe to give her children belladonna (and, yes, I *do* mean 'deadly nightshade') "because it's natural".

  20. Re:Do you honestly believe that something that has by Anonymous Coward · · Score: 0

    I never discount the ability of idiots to rationalize.

  21. People should be less arrogant and more interest by stein.dagostini · · Score: 3, Interesting

    I was too a very skeptical person, until I got a hormonal production disorder (I really don know its name in english, maybe later i can find a translation) that Western medicine said was impossible to cure and had to be countered with massive doses of neutralization of hormone medicines that would basically cripple me completely forever. I gave a shot and tried acupuncture since even death was better than those side effects. In 2 months the disorder was completely under control without any changes in my life but acupunture. The exams shown a reduction on the hormone production of more than 70%. I tough, ok that must be coincidence... stoped the treatment. Few months later the issue was back. Restarted the treatment and 1 month later was all under control again.... Even the doctors said to me, forget western medicie and stick to what is working. Since then I tried acupuncture for a lot of things, including issues that western medicine never was able to cure me like allergic reactions etc. I am still quite skeptical about almost everything, but I was faced with undeniable evidence that it has some VERY interesting results. People should spend less time trying to proof its or its not BS and more time trying to understand how to make people life better! And I pity the poor should that had the same diagnostics as me and went for the western "fully scientific" treatment. Medicine should be about saving people and making them feel better! Not about having reason about anything! Fool is the one that speaks without having real experience about it. Fool is the one that condems others to suffering just because the better path doe snot match his own beliefs. That is basically the same thing as religious fundamentalist.

  22. Storm by Anonymous Coward · · Score: 0

    A little bit off topic, but if you've ever ranted about what crap new age medicine is, you'll get a chuckle out of this:

    http://www.youtube.com/watch?v=V0W7Jbc_Vhw

  23. Induced Pain by LordAzuzu · · Score: 1

    I hate reading when scientists induce pain in animals to "try" to relief it.

    1. Re:Induced Pain by Sir_Lewk · · Score: 1

      Then I advise you to avoid medical journals. Would you rather they induce pain in you then try to relief it?

      --
      "linux is just DOS with a UNIX like syntax" -- Galactic Dominator (944134)
    2. Re:Induced Pain by LordAzuzu · · Score: 1

      We should have let nature go it's way, since the beginning. Maybe we would be extinct by now.

      "May we live long and die out"
      http://www.vhemt.org

    3. Re:Induced Pain by Sir_Lewk · · Score: 3, Insightful

      We should have let nature go it's way, since the beginning. Maybe we would be extinct by now.

      If that is really your goal, feel free to lead by example.

      --
      "linux is just DOS with a UNIX like syntax" -- Galactic Dominator (944134)
    4. Re:Induced Pain by LordAzuzu · · Score: 1

      I will, don't worry, when the time comes.
      In the meantime, I'm not going to breed.

    5. Re:Induced Pain by Sir_Lewk · · Score: 1

      When what time comes? You are a waste of resources right now.

      --
      "linux is just DOS with a UNIX like syntax" -- Galactic Dominator (944134)
  24. studies with "sham needles" by Mr.+Slippery · · Score: 1

    Chinese medicine has always included acupressure as an effective treatment. Indeed, it predates acupuncture -- not surprisingly, people noticed "it feels better if I press and rub here" before they thought, "hey, what if I stick a bamboo splinter into my skin so I can stimulate that point but free up my hands?" Pick up an acupuncture products catalog and you'll find a variety of "pellets" which can be taped to the skin to stimulate the points without puncturing the skin.

    So at best, "sham" needles -- i.e., acupressure -- as a control for acupuncture is like using aspirin as a control while investigating a new painkiller.

    The study that Yong (not "Tong") mentions also featured treatment via a set of points determined in advance by one therapist, and delivered by another. But when I see my acupuncturist (or even when I give a shiatsu treatment including the use of acupressure points), point selection is determined in part by the response to earlier points. So this is rather different than acupuncture as practiced by knowledgeable practitioners.

    That study also excluded patients with previous acupuncture treatment for any condition; based on my experience, however, it seems that it takes some experience with acupuncture to learn how to give feedback to the practitioner, to recognize and report the de qi sensation, so the effectiveness of the treatment increases with experience. (Perhaps there is also something like the habituation required for a cannabis "high" at work here, with the patient learning to interpret and respond to new sensations.) And the study also excluded those with "specific causes of back pain", so would seem to likely include a high proportion of those whose complaints had a strong psychosomatic component, and so would be poorly suited to investigating the physiological mechanisms involved.

    This is all too representative of the problems with much acupuncture research: what gets tested often has little to do with Chinese medicine as it is applied by knowledgeable practitioners.

    Despite these problems, this study found that "Compared with usual care, individualized acupuncture, standardized acupuncture, and simulated acupuncture [i.e., acupressure] had beneficial and persisting effects on chronic back pain." Nor does the study's comparison of individualized acupuncture vs. standardized acupuncture justify Yong's claim that it did not matter where the needles were placed. It takes some twisting to interpret this study the way that Yong would like to.

    And of course the placebo effect plays a role -- as it does in any treatment, including surgery. If my acupuncturist is doing nothing beyond triggering a placebo response in me, the results are still real, and what I pay her for the little show she puts on that lets whatever part of brain is responsible do its thing, is a bargain.

    (My bias: I'm and NCCAOM Diplomate in Asian Bodywork Therapy; my practice is a small sideline to my computer geek day job.)

    --
    Tom Swiss | the infamous tms | my blog
    You cannot wash away blood with blood
    1. Re:studies with "sham needles" by cosmicaug · · Score: 1

      Yes, this always comes up (and indeed it has come up here a bunch of times, already). Whereas aspirin (or the latest psoriasis treatment tested in a double blind placebo controlled trial) works exactly the same for everyone all of the time under every conceivable condition, the "alternative medicine" treatment du jour is simply too special to be examined in any sort of an objective way.

      Of course, this is, ultimately, bullshit.

      What it really means is no one has ever demonstrated the safety and effectiveness of the "alternative medicine" treatment du jour and, dammit, we like it that way!

    2. Re:studies with "sham needles" by Reziac · · Score: 1

      [hefting my copy of the Physicians Desk Reference to Herbal Medicines] Because if the plethora of side effects, harmful or even lethal effects, drug interactions, and contraindiations ever became public knowledge, a whole lot of very profitable quackery would go out of business... ...at least until the next generation of new-ager 'educated idiots' came along with their desire to believe in "magic".

      --
      ~REZ~ #43301. Who'd fake being me anyway?
  25. more things in heaven and earth by Anonymous Coward · · Score: 0

    Skim away at the scientific papers and you'll find lots or reproducible results regarding, for one, nitric oxide. And there's 2000 years of folk medicine success stories. Anyone who scoffs at the idea of "mysterious meridians" is under the illusion that physiological science has been reduced to engineering by "western" medicine. It hasn't. There is still a lot we don't understand about biological systems. Now lots of these papers do not have western names attached ... The meridian theories may be nothing but a superstition, may be a placebo and may have to do with undiscovered, by the empirical community, biological systems. The jury is still out.

    There are more things in heaven and earth, Horatio,
    Than are dreamt of in your philosophy.

  26. Re:Water Divining by nullchar · · Score: 3, Informative

    Uh, that's because most water tables are large, so if you are above one, you can pretty much poke a well anywhere and find water. Of course the depth of each well may vary depending on substrate and which water table you actually hit. Also, the rate of available water (to pump or even if naturally pressurized) depends on the water table you strike.

    Sorry man, you fell for the scam. (He may have "witched" past wells in the larger area and has studied the underlying aquifers. Every well drilled to depth and through various substrate will inform him. Shit, he may be a Geology drop-out.)

  27. Re:People should be less arrogant and more interes by Anonymous Coward · · Score: 0

    I have to agree very much with this. The science versus belief thing is an escalating conflict reflected in current events all over the world but also affecting the choices and decisions we make every day through our hearts and minds. Doesn't it seem over and over again like there's too much arrogance and everyone's fighting so hard to be perceived as the grand almighty authority over reality? What happened to the grace and understanding of Jesus Christ, and what happened to the heightened objectivity of scientists? It seems that both sides are gleeful in seeing the other fail and less interested in stating their case on it's own merits as part of their duty.

  28. Mechanism is helpful but not necessary by jfengel · · Score: 1

    Mechanism is often lacking even in regular science, especially in medicine. Biochemistry and physiology are complicated, and we often have only a vague idea (if that) about what makes a particular drug work.

    But mechanism isn't a necessary part. What is necessary is that something have measurable, demonstrable, repeatable effects. If you don't have that, you've got nothing. And this is especially important in medicine, where wishful thinking is extremely easy; people will fool themselves into thinking something helps, because they want it so desperately.

    That's aside from the placebo effect, where things actually can have some some measurable benefits despite the explicit lack of mechanism. That's because the mechanisms are very complicated, and mental state can be a mechanism all by itself.

    Science is most effective when it knows the mechanism, and science of all human endeavors is uniquely suited to finding mechanisms. That's because it starts with an insistence on measures, which gives you some idea what the "whole" is as you break it down into the "sum of the parts".

    From mechanisms you can work forward with better efficiency. That doesn't mean you can't make progress without them, and much of medicine starts with a guess rather than a mechanism, e.g. maybe this willow bark will help with the headache. That guess becomes science once you can measure the effect.

    When a scientist claims a "lack of mechanism", it happens in conjunction with a lack of demonstrated effect. It's like piling on: not only doesn't it work, there's no reason to believe it could work, so there's nowhere to go from here. At that point, pursuit of the guess usually stems solely from wishful thinking and not from any commitment to objectivity.

  29. Re:People should be less arrogant and more interes by OnTheEdge · · Score: 1

    Hey, if something works for you, great -- even if it doesn't have the proper evidence to support it. Everyone needs a good placebo in their back pocket. Hell, there's even a remote/outside/small/minuscule chance that something about you is different than the rest of us and said treatment does actually work on you in some unknown way. Great. But really, I don't care how far out and strange a treatment may sound, it can be tested, but that takes time and money. People truly interested in helping their fellow humans out will spend the time and money to do the proper testing and those just trying to make a buck off the gullibility of our fallible human minds won't. Where do you want to put your trust?

  30. Re:Water Divining by Antique+Geekmeister · · Score: 1

    It may not be fraudulent. He or she may be actually picking up clues, from experience, that a local farmer may not notice. Plant growth is certainly a useful indicator: layout of rock and hills may indicate where water from upstream or uphill is likely to channel into a particularly effective and reliable aquifer, effectively funneled by the underlying rock. That sort of expertise takes actual travel and study and practice that a local resident wouldn't have until pretty recently in history, so a traveling expert could be well worth the cost, even if they don't realize what they're an expert _in_.

  31. Re:People should be less arrogant and more interes by Anonymous Coward · · Score: 0

    Selection bias is your enemy.

    I gave a shot and tried acupuncture since even death was better than those side effects. In 2 months the disorder was completely under control without any changes in my life but acupunture. The exams shown a reduction on the hormone production of more than 70%.

    I tough, ok that must be coincidence... stoped the treatment. Few months later the issue was back. Restarted the treatment and 1 month later was all under control again....

    Yes, you started the treatment when you were worst, then stopped it when you were better. Natural cycles occur in MANY diseases, you can control it without acupuncture, just have to believe you can.

    Medicine should be about saving people and making them feel better! Not about having reason about anything! Fool is the one that speaks without having real experience about it. Fool is the one that condems others to suffering just because the better path doe snot match his own beliefs. That is basically the same thing as religious fundamentalist.

    Ou contraire, I have experience with it. Some time ago most of my family got some kind of virus that induced vomiting and other shit. My brother got it, and got better on all-natural-herbal-remedy for half a day. Then I got sick and got my brother's medicine, but didn't take it. Got better in half a day. So it clearly doesn't work, but the suggestive bias was enormous.

    Why is warning against unproven treatments "condemning others to suffering", but selling junk that simply doesn't work is moral and helpful?!?!?! Are you aware that there are homeopatic "treatments" for anthrax and radiation?

  32. Re:People should be less arrogant and more interes by TubeSteak · · Score: 5, Insightful

    In 2 months the disorder was completely under control without any changes in my life but acupunture.

    Your anecdotal evidence is fantastic.
    Now lets find 100 other people with the same positive outcome and figure out why acupuncture is working for all of you.

    People should spend less time trying to proof its or its not BS and more time trying to understand how to make people life better!

    ::facepalm::
    I'm glad your life is better, but many of us are not happy having gaps in our knowledge and filling in the blank with "magic" or "it works".
    If acupuncture works so well, understanding why/how is critical for having it turned into a mainstream treatment.

    --
    [Fuck Beta]
    o0t!
  33. Re:People should be less arrogant and more interes by stein.dagostini · · Score: 1

    Anedoctal? Depend on how you observe it. FACT is western medicine said (several doctors) I should be dead without that medicine or crippled usign it. Eastern medicine said I would live an OK life. FACT I am alive.. That leads to simple FACT that western medicine is NOT OWNER of the TOTAL truth (not saying the Eastern one is either). The WHOLE concept of eastern medicine is around principles that statistical annalysis is NOT A PROOF of anything, because youa re an individual, not a "representation of a popualtion" and the cure must be for YOU, not for the statistic. Until people can understand that there exist this fundamental rift in views of what define truth neither sides will ever agree on anything. I am skeptical on general sense of the word, SPECIALLY upon statistic being used as a tool to define the truth.

  34. Re:People should be less arrogant and more interes by stein.dagostini · · Score: 1

    You touch slightly a very important point. Eastern medicine does to treat you as a sample of a population. you are an individual and the treatment is INDIVIDUAL for every person the same treatment will NOT be applied for different persons even with exact same sympthoms. All their medicine is based on the fact that you are and individual and tatistical annalysis means nothing to them. And I will surely put my trust today in the person that treats me, not the person that tries to treat a mythical NON EXISTENT generic human from a statistical representation based on a generic population.

  35. Re:People should be less arrogant and more interes by Threni · · Score: 1

    Western medicine, eh? What has it ever done for you? Why can't the west be as clean, disease free and as long living as those eastern countries?

  36. Re:People should be less arrogant and more interes by stein.dagostini · · Score: 1

    I forgot to add something. I amnot saying you shoudl jsut leave as magic and forget it. But the problem is a LOT of people put VERY hard efforts into just trying to prove its false no matter what. They just call things BS when they don match with their beliefs, and that is NOT scientific behavior. We should try to understand how it works. But for that you must first stop thinking that the way we analyse things is an undeniable and indisputable universal truth! While people keep trying to analyse eastern medicine as they analyse western one ( basically around statistics) you will never understand it! Statistics are not LAWS of nature, we are not a sample of a statistic pool and that is fundamental to try analyse acupuncture. Its like trying to understand the qualities of a poetry written in russian, reading only its translation to portuguese! Even worse is like trying to evaluate the quality of russian poetry by making statistical analysis of how well it sound to Brasilians reading it in French!

  37. Re:People should be less arrogant and more interes by ChromeAeonium · · Score: 1

    Poe's Law rears it's head once again.

    In case people actually took that seriously, fisrt off, there is no such thing as 'western' medicine. That's a load of crap to try to act as if there are two valid forms of treatment. There aren't. There is scientifically proven medicine, and medicine that has not been proven/has been disproven. And that part about not trying to prove stuff, that's either great parody or bad logic. Anything that works, works. The proof of the pudding is in the tasting. If a treatment works, it can be shown to work under proper trials. Acupuncture, like most alternative medicines, has not shown this. And that bit about fully scientific treatment, all science is is observation. That's it. Science is what can be seen, and until a thing is seen, science ramains unconvinced of the thing's existence. If homeopathy worked, or ghosts were real, or if there really were qi lines and crap, science would be able to at least observe them, even if we could not truly understand them.

    That is basically the same thing as religious fundamentalist.

    “You’re so sure of your position
    But you’re just closed-minded
    I think you’ll find
    Your faith in Science and Tests
    Is just as blind
    As the faith of any fundamentalist”

    “Hm that’s a good point, let me think for a bit
    Oh wait, my mistake, it’s absolute bullshit.
    Science adjusts it’s beliefs based on what’s observed
    Faith is the denial of observation so that Belief can be preserved.
    If you show me
    That, say, homeopathy works,
    Then I will change my mind
    I’ll spin on a fucking dime
    I’ll be embarrassed as hell,
    But I will run through the streets yelling
    It’s a miracle! Take physics and bin it!
    Water has memory!
    And while it’s memory of a long lost drop of onion juice is Infinite
    It somehow forgets all the poo it’s had in it!

    You show me that it works and how it works
    And when I’ve recovered from the shock
    I will take a compass and carve Fancy That on the side of my cock.”
    -Tim Minchin, "Storm"

  38. Not so fast by Anonymous Coward · · Score: 0

    FTA ....

    The team also found that if they activated adenosine in the same tissue areas without applying acupuncture, the animals' discomfort was similarly reduced, strongly suggesting that adenosine is the magic behind the method. ....

    So it worked the same if they did acupuncture or didnt do acupuncture. What does this say about the quality of the study?

    1. Re:Not so fast by Chris+Burke · · Score: 1

      So it worked the same if they did acupuncture or didnt do acupuncture. What does this say about the quality of the study?

      It says it's a good study, because they isolated adenosine as being the cause of the pain relief. If they hadn't done that, they couldn't say for sure that the adenosine released by the acupuncture was the mechanism.

      --

      The enemies of Democracy are
  39. Re:People should be less arrogant and more interes by Anonymous Coward · · Score: 0

    I have had headaches for several years after half an hour of sun exposure on the dot. Not any light, but sun.
    After having acupuncture, it went away and never came back.

    Now find another 99 people.

  40. Re:People should be less arrogant and more interes by osu-neko · · Score: 1

    People should spend less time trying to proof its or its not BS and more time trying to understand how to make people life better!

    This sentence is self-contradictory. Understanding of what works and how it works is required to understand how to make people's lives better. In order to do the thing you say we should spend more time doing, we need to do the thing you say we should spend less time doing.

    --
    "Convictions are more dangerous enemies of truth than lies."
  41. Re:People should be less arrogant and more interes by TubeSteak · · Score: 1

    Anedoctal? Depend on how you observe it.

    Not at all.
    You don't seem to understand the difference between anecdotal evidence and scientific evidence
    Taking your one case and stretching it to conclude "acupunture works" is anecdotal.
    http://en.wikipedia.org/wiki/Anecdotal_evidence

    The WHOLE concept of eastern medicine is around principles that statistical annalysis is NOT A PROOF of anything, because youa re an individual, not a "representation of a popualtion" and the cure must be for YOU, not for the statistic. Until people can understand that there exist this fundamental rift in views of what define truth neither sides will ever agree on anything.

    Statistics are the best we can do when dealing with 6 billion unique genetic combinations.
    Maybe some day we'll discover that the spiritual aspects of eastern medicine are valid,
    but until then, things like "scientific evidence" and "statistical analysis" are what we have.
    Like I said before: Lets find 100 other people and figure out why acupuncture is working for all of you.

    While people keep trying to analyse eastern medicine as they analyse western one ( basically around statistics) you will never understand it! Statistics are not LAWS of nature, we are not a sample of a statistic pool and that is fundamental to try analyse acupuncture.

    For fuck's sake.
    Propose an alternative method of analysis that is valid and reproducible.
    If you can't do that, we'll stick with what's worked so far: the scientific method.

    --
    [Fuck Beta]
    o0t!
  42. It is mainstream by Krishnoid · · Score: 1

    Now lets find 100 other people with the same positive outcome and figure out why acupuncture is working for all of you.

    Or find some people who have had multiple doctors shrug their shoulders at, who have received reliable, repeatable relief from acupuncture, and just be grateful that there was something that provided a solution when western medicine failed them. Or you can present your argument to these people and see if it provides them relief.

    I'm glad your life is better, but many of us are not happy having gaps in our knowledge and filling in the blank with "magic" or "it works".

    Many people who have gotten relief would trade that kind of unhappiness for relief from the physical symptoms they experienced. It works well in some cases, and for those people, understanding why/how is not critical for relief.

    If acupuncture works so well, understanding why/how is critical for having it turned into a mainstream treatment.

    Go to China or Japan, try arguing that acupuncture is not a 'mainstream treatment', and see how far you get.

  43. Wuss by Anonymous Coward · · Score: 0, Troll

    And you're an asshole. No one cares about your fake headaches. Try to get attention in a more constructive way.

    1. Re:Wuss by fishexe · · Score: 1

      No one cares about your fake headaches.

      Actually, given that there's an article on the front page of /. about "fake" treatments having a real effect on headaches, I would say somebody cares.

      --
      "I don't care about the Constitution!" --Bill O'Reilly, November 17, 2009
  44. More than just the placebo effect by jhylkema · · Score: 1

    From a scientific standpoint, the beginning and the end of the argument is this: Acupuncture posits that (1) energies within the body travel (2) along certain routes and (3) can be redirected using needles with the effect of (4) curing or treating human disease. There is exactly zero evidence to support any of these, charitably, very farfetched claims.

    Skeptics very accurately point out that the placebo effect is very powerful and is not fully understood. However, more than that explains why acupuncture doesn't go the way of bloodletting, trepination or any of a hundred other quackeries over the centuries. Confirmation bias is a big one. A patient has just paid big bucks to a TCM practitioner and desperately wants to believe that the treatment will work. Of course, if the treatment doesn't work, the patient is a fool and wasted his money. No one wants to be thought of as a fool even by himself, so the patient will believe the treatment worked and his/her imagination will fill in the gaps.

    Another aspect to this is good old fashioned Western (particularly American) racism, ignorance and cultural imperialism. Since the "medicine" is coming from an almond-eyed gentleman with darker skin, a thick accent and with office decor written in strange foreign characters, it's "different" and "exotic," so by extension it has to be "cool" and thus must be effective.

    Finally, there's a much simpler aspect. A sick person who feels like traditional medicine has failed him/her visits a TCM practitioner. Generally speaking, said TCM practitioner is a kindly gent with a grandfatherly demeanour who looks and sounds like Mr. Miyagi (see above re: "exotic"). Said gent listens to the patient unhurriedly and may genuinely want to help and may genuinely believes that what he has to offer will help. Anyone would feel somewhat better in that situation and that temporary relief is enough to make people want to come back for more and to shell out more of their money.

    The trouble with this, of course, is that people will continually seek the temporary succor provided by the quacks while delaying or avoiding those who can actually treat the underlying problem. This can cause the underlying problem, particularly something like cancer, to move from the treatable stages to the untreatable.

  45. Re:People should be less arrogant and more interes by Anonymous Coward · · Score: 0

    Then, it may come as a surprise to you that acupuncture actually gets quite a lot of research attention recently. Even although we do not know exactly how it works (and some of the mysticism surrounding it is BS), it
    does have an significant effect. Unfortunately, most of the clinical trials happen in China, and since many people (probably correctly, I am working there now) have doubts about the scientific standards employed here, I can
    understand your scepticism. Nevertheless, there are several international groups (one in my institute) working on this.

    Nevertheless, the fact we can not say why (how) it works yet, it does not mean it does not work at all.

  46. Researchers are getting ahead of themselves by Anonymous Coward · · Score: 0

    There have been done quite a number of studies as to the efficacy of acupuncture. Rather than showing an effect is there, we are concluding with ever increasing certainty that acupuncture is ineffectual. For example, it does no better than stinging people at random spots. And if you hide the needles from sight, it still works - even when you don't actually pierce the skin. In any case, when you're speculating how X might work, when there is no indication that X actually works, you're getting ahead of yourself.

  47. Re:People should be less arrogant and more interes by Anonymous Coward · · Score: 0

    In 2 months the disorder was completely under control without any changes in my life but acupunture.

    Your anecdotal evidence is fantastic.
    Now lets find 100 other people with the same positive outcome and figure out why acupuncture is working for all of you.

    People should spend less time trying to proof its or its not BS and more time trying to understand how to make people life better!

    ::facepalm::
    I'm glad your life is better, but many of us are not happy having gaps in our knowledge and filling in the blank with "magic" or "it works".
    If acupuncture works so well, understanding why/how is critical for having it turned into a mainstream treatment.

    that 100 people is all over China. It is THE mainstream treatment over there.
    but of course, Western medicine is practiced as well.

    i would prefer that both forms of medicine is used to treat what's best for the patient.