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DNA-Less 'Red Rain' Cells Reproduce At 121 C

eldavojohn writes "A new paper up for prepublication from the controversial solid-state physicist Godfrey Louis claims that the cells Louis collected from a Keralan red rain incident divide and produce daughter cells at 121 degrees Celsius. While unusual, this is not unheard of as the paper recalls cells cultivated from hydrothermal vents are known to reproduce at 121 C as well. Of course, caution is exercised when dealing with the possible explanation surrounding the theory of panspermia but the MIT Technology Review says researchers 'examined the way these fluoresce when bombarded with light and say it is remarkably similar to various unexplained emission spectra seen in various parts of the galaxy. One such place is the Red Rectangle, a cloud of dust and gas around a young star in the Monocerous constellation.'"

41 of 149 comments (clear)

  1. Monocerous(sp) by Anonymous Coward · · Score: 4, Informative

    That's Monoceros - Unicorn. It's not an adjective with the "ous" ending.

    1. Re:Monocerous(sp) by Anonymous Coward · · Score: 3, Funny

      Maybe the adjective is appropriate if we have panspermia coming from the horny constellation.

  2. "Up for prepublication"? by 93+Escort+Wagon · · Score: 5, Insightful

    What does that mean? Has it been peer-reviewed yet? Has it been accepted? Or is it just at the stage where the author's submitted it, and those other steps still need to happen? The linked page only says its "submitted".

    If it hasn't been accepted, posting it here is rather silly on a lot of counts. Not to mention that, with some journals, doing something like that can result in the paper being summarily rejected (e.g Nature, Science).

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    1. Re:"Up for prepublication"? by DamienRBlack · · Score: 4, Insightful

      None of this guy's (Godfrey Louis) stuff on the subject seems to be peer reviewed. It is all just up on arXiv. I think he is more interested in getting publicity than getting his facts checked. Now that last statement is an ad hominem, so it doesn't say anything about his research one way or the other. But I think it does give a few clues.

    2. Re:"Up for prepublication"? by SoftwareArtist · · Score: 4, Informative

      arxiv.org is a non-peer-reviewed preprint repository widely used by the physics community. "Submitted" means exactly what it says: it's just listing the date that article was submitted to arxiv.org. This work will undoubtedly be submitted elsewhere also. For more information, see http://en.wikipedia.org/wiki/Arxiv.

      --
      "I'm too busy to research this and form an educated opinion, but I do have time to tell everyone my uninformed opinion."
    3. Re:"Up for prepublication"? by SoftwareArtist · · Score: 2, Informative

      None of this guy's (Godfrey Louis) stuff on the subject seems to be peer reviewed.

      Incorrect. Quoting from the linked article: "Louis published his results in the peer-reviewed journal Astrophysics and Space in 2006, along with the tentative suggestion that the cells could be extraterrestrial."

      --
      "I'm too busy to research this and form an educated opinion, but I do have time to tell everyone my uninformed opinion."
    4. Re:"Up for prepublication"? by jdpars · · Score: 2, Interesting

      When did astrophysicists start peer-reviewing biology-related articles authoritatively?

    5. Re:"Up for prepublication"? by spun · · Score: 5, Insightful

      It isn't really an ad hominem at all. If you say "This guy is a loon, therefore his arguments are crap" then that is an ad hominem, but if you say "This guy's arguments are crap, therefore he's a loon" it isn't. His being a loon doesn't necessarily make his arguments crap, but just saying his arguments are crap or even calling him a loon isn't an ad hominem. An ad hominem is a specific type of logical fallacy, it is not a general insult.

      --
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    6. Re:"Up for prepublication"? by Anonymous Coward · · Score: 4, Interesting

      I can't vouch for the following, but.... According to critics, the reason that DNA wasn't seen in light microscopy was because a) he used the wrong kind of stain, which doesn't typically work for algae, b) this is an algae spore, c) the walls of the spore are too strong for most stains to absorb into it, and d) the walls also impede light microscopy, making it even more challenging if he did use the right kind of stain. There is a discussion of that in wikipedia under "criticisms" http://en.wikipedia.org/wiki/Red_rain_in_Kerala

    7. Re:"Up for prepublication"? by SoftwareArtist · · Score: 4, Informative
      From the journal's website (http://www.springer.com/astronomy/journal/10509):

      Astrophysics and Space Science publishes original contributions and invited reviews covering the entire range of astronomy, astrophysics, astrophysical cosmology, planetary and space science and the astrophysical aspects of astrobiology.

      Note the last one: astrobiology is within the scope of that journal. Given that, the editors are certainly knowledgeable about who else works in that field, and can find appropriate reviewers for an astrobiology article.

      --
      "I'm too busy to research this and form an educated opinion, but I do have time to tell everyone my uninformed opinion."
    8. Re:"Up for prepublication"? by wjousts · · Score: 3, Informative

      Yeah, seriously. Somebody mod the parent up here. An astrophysicist fails to extract DNA? Well how about letting a Biologist have a go. It's kinda there thing.

      Besides (according to Wikipedia), the official report said they cultured them already. They are alga spores belonging to the genus Trentepohlia.

      I think Occam's razor applies here.

    9. Re:"Up for prepublication"? by wjousts · · Score: 2, Informative

      Sorry, should be "It's kinda their thing."

    10. Re:"Up for prepublication"? by MightyMartian · · Score: 5, Insightful

      If it was me, I would make sure that every i was dotted and t was crossed. I would keep it damned quiet, and ask anyone I shared the data with to do the same. I would probably spend six months just running through it all again, and maybe once more after that.

      The one thing I wouldn't do is leak it, or fantastically optimistic interpretations of it to the press. When things appear first in the media and then in peer-reviewed journals or at conferences, people begin to think strange thoughts like "Hyperbole" or, sometimes even "Fraud". Researchers who leave the confines of accepted publishing and announcement practices are taking a big chance that they're going to undermine the whole damned thing.

      But how many times, folks, have we been bit by incredible announcements in the press "New Discovery Will Rewrite biology/astronomy/physics/neurology/whatever" only to find out that the actual paper is considerably more mundane.

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    11. Re:"Up for prepublication"? by biryokumaru · · Score: 3, Informative

      You may also note that the guy who did use the right stains and looked for algal DNA made certain it was clear that he could not make a solid determination one way or the other.

      --
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    12. Re:"Up for prepublication"? by Anonymous Coward · · Score: 5, Insightful

      It is not peer reviewed. I took a look at it and in its current form it is unlikely to pass muster for peer review (at least in a molecular biology journal). There are a number of clear flaws. Cells of some species will often show a characteristic doubling time. In this case, the "cell" population appears to less than double from 30 to 60 minutes. Then from 60 to 90 more than double before any increase in cell number stops. This odd behavior is consistent with micelles treated at high heat breaking apart into smaller micelles before reaching a stable size (which, assuming these data are not falsified, seems to be what is occurring here).

    13. Re:"Up for prepublication"? by icebike · · Score: 4, Insightful

      Somehow I suspect we would not be discussing this if a crackpot was not involved.

      The wiki article pretty much nails it down to spores of a lichen-forming alga belonging to the genus Trentepohlia, plentiful in the area where the red rain was found, as well as many other places in the world.

      Yet, we are now treated to the suggestion that because the same wave lengths of light as are found in some remote part of the galaxy can be induced when samples are bombarded with some (conveniently unspecified) light source..

      The clear implication being that we should all believe that some extraterrestrial life has chosen this particular part of India, (and no where else) to fall in rain for a solid month, totally ignoring high winds aloft.

      I wager my rear end could be made to fluoresce certain shades of red found in other parts of the galaxy given the right form of bombardment.

      Thank you sir, Mr Louis needs another.

      --
      Sig Battery depleted. Reverting to safe mode.
    14. Re:"Up for prepublication"? by spun · · Score: 2, Insightful

      >implying that arguments made by a loon aren't crap.

      Please, learn to think.

      Huh? I'm not implying that arguments made by a loon are good or bad. Loons can make any sort of argument, and even a stopped clock is right twice a day. The argument is either logical or it isn't, that holds true for whoever makes the argument. That is why ad hominem is a fallacy.

      Now, there are times when calling someone a loon is not an ad hominem. For instance, "Don't listen when George tells you he is king of Siam. George is certifiably insane" is not an ad hominem if George is in fact insane and not the king of Siam, the fact of his insanity a good reason not to listen to his claims, and therefor this argument is not a fallacy.

      --
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    15. Re:"Up for prepublication"? by fractoid · · Score: 2, Interesting

      I must admit, I'm developing a healthy skepticism of any such announcement coming out of India. I'm sure there are millions of very capable, respectable scientists there but there's also a large element of superstitious nonsense, and it seems to be this element that's running the media. *sigh* It's like that guy claiming to have not eaten for 60 years because he sustains himself purely on yogic vedic nonsense. Funny how they announced they were observing him closely, and then just went quiet about it after a few days... no big article saying "yep, old guy is just another faker" though.

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    16. Re:"Up for prepublication"? by yyxx · · Score: 3, Insightful

      The wiki article pretty much nails it down to spores of a lichen-forming alga belonging to the genus Trentepohlia, plentiful in the area where the red rain was found, as well as many other places in the world.

      Spores don't divide at 121C or 300C.

      Yet, we are now treated to the suggestion that because the same wave lengths of light as are found in some remote part of the galaxy can be induced when samples are bombarded with some (conveniently unspecified) light source..

      Fluorescence doesn't work that way.

      Somehow I suspect we would not be discussing this if a crackpot was not involved.

      Well, what defines a "crackpot"? The people described their materials, methods, and results. Those are not consistent with spores. There are three possibilities: (1) the experiments were carried out incorrectly, (2) the authors deliberately lied, or (3) the experimental results are as described.

      How can one proceed? Peer review may uncover gross errors in their experimental procedures, in which case they would have to go back and redo their experiments.

      If there are no gross errors, there's no reason not to publish the results; they are still implausible, but not obviously wrong.

      The only way to figure out what's going on is to try and replicate the experiments a few times. Once people do that, we'll know. Until that's done, the issue is simply unresolved. There's no need to call people "crackpot" over it, but there's no reason to believe the results either.

  3. Re:Red blood cells also do not have DNA by Pojut · · Score: 3, Funny

    That's what you thin-

    **NO CARRIER**

  4. Apologies in advance... by Jedi+Alec · · Score: 2, Funny

    But I've had a few drinks and I just can't resist...

    I'm in ur nightskiez panejaculating on ur planetz!

    Soooo worth the karma.

    --

    People replying to my sig annoy me. That's why I change it all the time.
  5. Re:Red blood cells also do not have DNA by StikyPad · · Score: 2, Interesting

    And the material found in the rain bears a striking, if superficial, resemblance to red blood cells.

  6. Re:What? by arkane1234 · · Score: 5, Funny

    Cthulhu is resting... :P

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  7. Re: Old info by Black+Parrot · · Score: 2, Interesting

    A cell wall was always a hard one to explain since we seem to jump from viruses to one cells organisms.

    Actually, the cell wall is just about the easiest thing to explain. Just take a bunch of short-chain molecules that are hydrophobic on one end and hydrophilic on the other and throw them in water, and the self-organize into pockets very like the cell wall.

    --
    Sheesh, evil *and* a jerk. -- Jade
  8. More recent publications... by stagg · · Score: 4, Informative

    It looks like more recent publications have resolved this: "The alga was identified as a specie belonging to the genus Trentepohlia. The region in Changanacherry from where the red rain was reported was found to be densely vegetated with plenty of lichen on trees, rocks and lampposts. Samples of lichen collected from there also were cultured in the microbiology laboratory of TBGRI. The study showed that the lichen collected from the site gave rise to algae similar to the ones cultured from the spores obtained from the rain water samples. The spores in the rainwater, therefore, most probably are of local origin." http://web.archive.org/web/20060613135746/http://www.geocities.com/iamgoddard/Sampath2001.pdf

    1. Re:More recent publications... by Idarubicin · · Score: 2, Insightful

      IANAS but it would seem to me that the presence of enough spores in the water samples to grow a culture from in not truly indicative of the red color being primarily or even partially from the spores. Given the concentration of spores needed to color water red, the probability of rain containing that concentration is very, very low.

      That isn't necessarily an argument for why the red color couldn't be spores; that's an argument for why red rains are quite rare, and why they require ideal and unusual conditions under which to occur. I would rephrase your statement to, "Given that the rain was red, the probability of the rain containing a sufficient concentration of spores to cause the coloration approaches unity". Given that we get full-scale animals falling from the sky from time to time, it's not that much of a stretch for occasional freak meteorological conditions to pick up a bunch of teeny tiny algal spores. From the last decade, the Wikipedia article I linked has stories about frogs and toads (several occasions), fish (twice), worms, and spiders. Spores are child's play.

      --
      ~Idarubicin
  9. Terminology needs to be less hyperbolic by Kupfernigk · · Score: 2, Interesting
    Actually reading the paper shows that the terminology used tends to assume what is to be demonstrated. Calling the objects "cells" and the structures that appear in them "daughter cells" is a little bit hyperbolic. They could equally well be called "bubbles" and "internal bubbles".

    Which is not to say they are wrong. There is a lot of speculation that neither DNA nor RNA were the actual encoding means of early life, but some other double helix that was more stable in the radiation and temperature extremes of early Earth. If this research justifies an in-depth study of what is in those hypothetical "nuclei" and what comprises that "cell membrane", that should tell us whether this is for real or whether it's some kind of nonliving artefact.

    --
    From scarped cliff or quarried stone she cries "A thousand types are gone, I care for nothing, no not one."
  10. Re:What? by seanellis · · Score: 4, Informative

    The official investigation concluded that they were spores from local algae, and that the initial DNA tests were flawed. Wikipedia has the details, as usual.

    To go from "our test found no DNA" to "there is no DNA" to "they must be extraterrestrial" to "they look like the dust clouds in Monocerous" is a series of leaps that go wayyy ahead of the available evidence, in my view.

    It would be very interesting to be proven wrong, however.

  11. Luckily... by fuzzyfuzzyfungus · · Score: 3, Informative

    Your standard flamethrower is capable of operation at well above 121c. Should be no big deal...

  12. Re: Old info by KarrdeSW · · Score: 3, Informative

    What you're referring to is called a cell membrane which is formed by lipid bilayers. Cell walls are usually more rigid and are located outside of the cell membrane.

    However, the parent is still confusing because algae, plants, protozoa, etc. all have different structures of cell walls. He doesn't really specify which specific one(s) are hard for us to explain.

  13. I for one... by obiquity · · Score: 2, Funny

    ...welcome our Red Rain daughter cell overlords.

  14. Re: Old info by wjousts · · Score: 2, Informative

    Indeed. And you probably have a bottle of suitable short-chain molecules, hydrophobic on one end, hydrophilic on the other end sitting on your kitchen sink. You probably know it better as "dish soap".

  15. Activate Wildfire by PinkyGigglebrain · · Score: 2, Interesting

    Andromeda has arrived.

  16. Doubtful claims by Chicken_Kickers · · Score: 4, Informative

    I am a microbiologist and this claim in my opinion is very weak. Remember, extraordinary claims need extraordinary proof to be accepted. This guy is a physicist, not a biologist, so that already raises many red flags.

    In the arXiv blog linked, it says that Godfrey collected numerous samples of the "red rain". Since he is not a microbiologist, I doubt he took the necessary precautions to prevent contamination with terrestrial microbes, though it is debatable whether this is even possible. This alone is the biggest stumbling block to his claims. The blog also says that the cell "reproduce" at 121C yet also states that it has no DNA (all form of nucleic acids?). This flies in the face of all known life on earth. Even red blood cells initially have a nuclei before losing them as they mature. The point of reproduction is to pass on your genetic code to your offspring. This suggests to me that we might be looking at a abiological/chemical process. Did Godfrey try to detect the production of metabolite byproducts from his sample? Reproduction is a very energy intensive biochemical operation and should produce detectable metabolites. My research field is hyperthermophilic Archaea that grows at 90C or more and I know the existence of microbes that can grow at even higher temperatures, so this part of the claim is feasible. Overall, I caution extreme scepticism until Godfrey can provide extraordinary proof of his claims.

    1. Re:Doubtful claims by smellsofbikes · · Score: 3, Interesting
      I'm in complete agreement with you, but some stuff occurs to me, in reading more about this.

      1. If he's just an attention whore, he could have found some weird bacterium that uses RNA and claim -- and be technically correct -- that there is no DNA. That'd be surprising, but not anywhere nearly as surprising as finding something that appears to be reproducing without nucleic acids.

      2. From other reading about red rain, it appears that his attempts to find DNA were restricted to malachite green and ethidium bromide, and the current theory by people who aren't him is that he's got a bunch of yeast spores, which are going to have cell walls impermeable to both so he's not going to detect DNA even if it's there, or at least not by such relatively crude techniques.

      3. I wonder about metabolites. If the stuff *is* from outer space, it might not have the typical ultra-fast metabolism we see in common Earth bacteria, where energy is plentiful and the only real competitive tool available to prokaryotes is rapid reproduction. Something from outer space might act more like some of the archaea or mycobacteria that take days to reproduce -- or years -- rather than the half-hour cycles we're used to seeing in many bacteria. If this thing has a reproductive cycle measured in days or months, it's going to take a lot of time and quantitative analysis to actually see it metabolising.

      4. While I agree with your statement that extraordinary claims require extraordinary proof, I do have to wonder: what explanation of the origin of life *isn't* extraordinary? Every theory of earth-bound biogenesis I've read is pretty difficult reading. This one does have the advantage of offloading the origin-of-life-on-earth, in which case you can at least claim that maybe biogenesis only happened once somewhere else and is being blown all over the Universe, rather than having only one planet and only a billion years in which to fit your explanation.

      --
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    2. Re:Doubtful claims by CheshireCatCO · · Score: 2, Insightful

      . This one does have the advantage of offloading the origin-of-life-on-earth, in which case you can at least claim that maybe biogenesis only happened once somewhere else and is being blown all over the Universe, rather than having only one planet and only a billion years in which to fit your explanation.

      How does that help, exactly? You still have the problem of abiogenesis somewhere. At least here on Earth you know you have the right ingredients in abundance and you don't need to invoke a low-probability transfer mechanism to explain how it got here.

      I'm not saying that this rules out panspermia, but it does make it seem like rather the more complicated option, all else being equal.

    3. Re:Doubtful claims by CheshireCatCO · · Score: 2, Informative

      We've demonstrated several times that bacteria -- and I believe lichens -- can at least survive extended exposure in low earth orbit, so at that point it's not difficult to believe they could get here from somewhere else.

      Yes and no. It's possible, provided they can survive for longer periods of time, to get living creatures from, say, Mars to Earth. The dynamics are tricky (it tends to take quite a while to get from one to the other, particularly if you don't want a high relative velocity when yous smack into the Earth) and lofting the material (and then landing it) in such a way as to not sterilize the rock is tricky. Couple that with the lack of conclusive evidence that life has existed on Mars in the past and I lean toward "less probable" for that route. Again, it doesn't rule it out, but it does take a backseat to local origin in my mind.

      (Also, note that Mars, or any other planet in our system, doesn't solve a timescale problem. In fact, the transit time makes it worse.)

      The other option is to get it here from outside our system. That does solve the timescale problem, potentially, but that adds a vast amount of time on to the transit. Any organism would have to be able to survive in space for millions, if not billions, of years. And the impact probability of a piece of interstellar junk and our system (let alone Earth) is awfully low. Plus, impact speed with an extrasolar bit of rock is a lot higher than from something already in our system. Barring a long series of orbital manuvers to alter the trajectory before meeting Earth (lower probability still), minimum relative speed at infinity is around 11 km/sec, assuming exactly optimal alignment. (More likely is in excess of 40 km/sec, and that's generously assuming that the speed relative to the Sun is very small.) Your minimum impact speed is therefore around 16 km/sec, which I can't imagine increases the odds of successfully seeding life here.

      Again, this doesn't rule it out, but this is just why I feel that panspermia creates more "problems" (where I mean "low probability requirements") than it solves.

  17. Andromeda strain... by mevets · · Score: 2, Funny

    Has anybody checked what pH they can reproduce at?
    After reading that book, I ingested copious amounts of acid to ensure I would be one of the survivors.

  18. Re:What? by Grishnakh · · Score: 3, Funny

    An obvious question is that if these cells divide at 121 degrees Celcius, what do they do in the extreme cold of space, just hibernate?

    Yes. That's how they get from planet to planet. Then, when some of them reach a planet and it gets hot enough, they divide and reproduce, and start growing other, more complex types of cells, and then quickly form intelligent beings who reproduce quickly into an army and take over the planet.

    Now that these researchers have figured out how to activate the seed cells, I expect the red-cell alien overlord army to rise up in a few weeks.

  19. Re:Just sequence them.. by ElektronSpinRezonans · · Score: 3, Insightful

    Ah, youngling, you have many years until you have that PhD in your hand. What you're suggesting is a negative results, caused from "not seeing what we wanted to see", which can be rebutted in a million different ways, most of which you probably do not know yet. This is one of the reasons the peer review process exists. I personally do not believe anything I read on a non-peer reviewed paper, unless of course it is coming from well documented, well funded full professors.

  20. Re:Just sequence them.. by yyxx · · Score: 2, Insightful

    I personally do not believe anything I read on a non-peer reviewed paper,

    A peer reviewer is just someone working in a field. If you need to rely on peer reviewers to determine whether a paper in your field is credible, you're simply not competent and should find a different job. For people working in a field, peer review is useful for cutting down the crap, not for establishing credibility.

    What you're suggesting is a negative results, caused from "not seeing what we wanted to see", which can be rebutted in a million different ways, most of which you probably do not know yet.

    Negative results like that are incredibly useful: either they show that a particular experimental approach fails, saving other people the effort to go down that path, or they are a new phenomenon. Keeping such results from getting published is really quite harmful to science, causing needless duplication of the same dead ends again and again.