Scientists Create Programmable Bacteria
wilmavanwyk writes "In research that further bridges the biological and digital world, scientists at the University of California, San Francisco have created bacteria that can be programmed like a computer. Researchers built 'logic gates' – the building blocks of a circuit – out of genes and put them into E. coli bacteria strains. The logic gates mimic digital processing and form the basis of computational communication between cells, according to synthetic biologist Christopher A. Voigt."
But how will they be able to find "bugs" in their program when the program is all bugs? Thank you, thank you, I'll be here all week, try the fish, the bacteria in it all programmed in Sea.... Oh I did it again!
I apologize profusely for whatever pain the above might have caused.
Monstar L
Does it run Linux?
Imagine a Beowulf cluster of these
1. Create Bacteria
2. program it
3. ????
4. Profit!
In Soviet Russia Bacteria programs YOU!
Think that covers everything.
I want a list of atrocities done in your name - Recoil
What do the University of California E-coli research team and Microsoft have in common?
They are both full of shit programmers
Finally we're gonna see a decent implementation of Conway's Game of Life!
Say you could tailor a bacteria to attack or compete with a bacteria which you needed to control. As the target mutates your attack vector could be reprogrammed accordingly.
Or how about extending the idea to build a programmable immune system? If the patients immune system has crashed you just feed in tailored bugs to keep infection under control.
http://michaelsmith.id.au
No matter how tight I wear my tinfoil hat, unless it is actually a full body suit and electrified on the outside, I think this will obsolete it. Imagine, cells turn cancerous if your black, gay, white, short, don't have any certain genetic or set of genetic markers. If you leave a certain atmospheric pressure, like come down off your mountain prison it reacts to a change in your body. If you pass or leave a magnetic field (or it accidentally loses power) you're a goner. I could go on and on.
While I can also think of the wonders this could allow, I think more of what could easily go wrong. When you have American scientists laughing because they gave the Russian's leukemia on accident with an early vaccine test, this doesn't make me feel any better.
Like a city whose walls are broken down is a man who lacks self-control.
I wonder how long before the viruses in the Virus Batteries "accidentally" combines with this programmable bacteria to form something to truly fear...
Hey, nobody said SkyNet had to be made from Silicon...
The media has been programming humans for ages now.
Don't fight for your country, if your country does not fight for you.
So ... are zombies the seg. fault? Broken pipe? Shit man, programming just got real.
.
So, they'll still be prone to bacteriophage viruses right?
“At some point, Microsoft Word had to have been converted to 1s and Os. It's the same way with cells," Voigt said. "What we've done here is created a fundamental language to show that they can work in bacteria. We still have a lot fewer circuits that you could use in computers."
*chuckles*
In the TNG episode "The Chase", it's discovered that aliens seeded the oceans of various planets with life and placed part of a computer program into the DNA distributed on each planet. When the various races (humans, vulvans, cardassians, etc) put the code together a billion years later they find an ancient race has left us a holographic message of goodwill and peace.
We Must do this! Except we change the message to play "Never gonna give you up", Rick Astley built right into the DNA of all living beings forevermore. Just waiting to be found in a billion years. Most epic troll ever.
Oh man.. can I take that back.. too slow.. must have e.coli for brains
Does he pass the Voigt-Kampf test?
Great I can program up projectile vomiting over my boss's desk, to get a few days off work as sick leave and then get the Programmable E. coli to stop 2 minutes after I leave the office. :)
There are 10 kinds of people in the world... those who understand binary and those who don't.
This sounds like one of those Greg Egan novels I read recently.. What was It... Steve Fever.... http://www.technologyreview.com/Infotech/19534/ Yep, thats it!
Timmy keep using my lunch to feed the computer! Not fair!
1. make programmable bacteria
2. release bacteria
3. people get infected
4. sue the infected people for copying the bacteria
5. profit!
Red Dwarf anyone? A programmable virus? We need never peel potatoes again!
Comment removed based on user account deletion
This was being done at MIT 10 years ago.
http://people.csail.mit.edu/rweiss/
Robust multicellular computing using genetically encoded NOR gates and chemical ‘wires’
I am not a Biologist. Can some one verify if this is the original paper?
-- It is the mark of an educated mind to be able to entertain a thought without accepting it. -- Aristotle
concerned about this? Oh sure, it won't get out of hand...just like the creation of the A-bomb didn't get out of hand. This one is more scary because it is bacteria. I thought we outlawed germ warfare (even though we know both sides kept up the research).
Instead of having bugs in our programs, we are going to have programs in bugs. What would happen if it supports recursion? Is it possible we humans have been looking down the call stack instead of up? OMG indeed. OMG is just one step up the call stack! OMG'sG!!!!
sed -e 's/Chuck Norris/Rajnikant/g' joke > fact
Let me be the first to welcome our programmed bug overlords in Soviet America where bugs have programs in Beowulf cluster.
sed -e 's/Chuck Norris/Rajnikant/g' joke > fact
I wonder how long till Intel starts marketing Petri dishes!
- but my news ticker gave me a virus...
I remember reading an ACM journal article back in 1984 or '85 about the possibility of doing this. And now, 25 years later, here we are.
Proverbs 21:19
Is there a cross-compiler for it yet?
Programmable bacteria are all well and good, but I would rather hear more about this synthetic biologist. Can he use contractions?
This is definitely news for nerds, but this phrase in the summary got me wound up:
Aargh! Surely someone who doesn't know what a gate is wouldn't be reading slashdot?
bacteria with builtin Bluetooth?
The ability to encode arbitrary information in DNA has applications in security and encryption.
Let's say Alice wants to send a plaintext message to Bob. Except with DNA it's always Bob sending plaintext DNA to Alice. OK I have to correct a little bit and replace "Alice" with "Bob" and "Bob" with "Alice"... eh, that didn't work because it replaced all the strings with "Alice".... ctrl-Z ctrl-Z ok let's do this right... first replace "Bob" with a swap like "Sue"... replace "Alice" with "Bob"... wait a second, Bob is sending his DNA to Sue. OK that's fine with Bob and Sue except halfway through the final replacement, Alice is going to find out that Bob has been sending DNA to Sue. How can we effectively hide this information from Alice? Start the swap by replacing "Alice" with "Peter". Oh no that really causes problems because still, Alice will start to wonder about Bob.
I've seen a lot of shitty software in my time
-- In the beginning was the WORD, and the WORD was UNSIGNED, and the main(){} was without form and void...
I am Legend!
Is that the biologist Christopher A Voigt?
One of the lines had the "mad scientist's" mum asking why on earth he'd want to make bacteria smart? The hero asked his mother, "Why are you so worried?" She answered, "Ask anyone that's ever cleaned a toilet bowl."
Obviously the programming language would be Mono.