Famous British Autism Study an 'Elaborate Fraud'
Charliemopps writes "An investigation published by the British medical journal BMJ concludes the study's author, Dr. Andrew Wakefield, misrepresented or altered the medical histories of all 12 of the patients whose cases formed the basis of the 1998 study — and that there was 'no doubt' Wakefield was responsible."
This guy tracked down subjects all the way over in the United States:
Child 11 was among the eight whose parents apparently blamed MMR. The interval between his vaccination and the first "behavioural symptom" was reported as 1 week. This symptom was said to have appeared at age 15 months. But his father, whom I had tracked down, said this was wrong.
"From the information you provided me on our son, who I was shocked to hear had been included in their published study," he wrote to me, after we met again in California, "the data clearly appeared to be distorted."
He backed his concerns with medical records, including a Royal Free discharge summary. Although the family lived 5000 miles from the hospital, in February 1997 the boy (then aged 5) had been flown to London and admitted for Wakefield’s project, the undisclosed goal of which was to help sue the vaccine's manufacturers.
Sadly, CNN couldn't even bother to have a single citation to the actual source text that is uncovering this. Of course they have all sorts of links internal to their site ... gotta keep those page clicks up, don't want eyeballs over at the BMJ.
My work here is dung.
Sadly, there's a lot of money in junk science.
People are still going to ignore all the retractions from the real medical and scientific community in favor of Jenny McCarthy saying on TV that "Vaccines gave my baby autism!"
This has grown beyond Wakefield now. It's become a self-sustaining conspiracy theory, independant of it's source, and no mere facts are going to even slow it down. Parents want to worry, it's in their instincts to protect their children - if they can find no real dangers, they'll inflate anything that looks remotely threatening regardless of true risk.
http://www.generationrescure.org/ already has it's rebuttal, including a NEW study which shows a link between Hepatitis-B shots and a 3 times higher risk of autism.
When will they stop?
It's a sad world when some money-grubbing fool can publish a fudged article claiming that a vital, lifesaving tool can cause horrible, debilitating disease, get international attention, and when he's finally disproven all the "concerned parents" of the world ignore him because The Man wants to keep their kids autistic, without sparing a thought to the possiblity that maybe The Other Man just wanted a quick buck.
Sent from my CR-48
Everyone knows how conspiracy theories work. All the wingnuts will just claim this is a political chop job designed to cover up Big Brother/Big Pharma's Big Evil plan. The BBC could play video next week of Wakefield snorting coke and doing an underage hooker, all the while shouting that he had falsified his results, and it wouldn't matter. At some point they'd probably decide that Wakefield was a deep-cover government plant intended to discredit the movement.
Why is this making the news now? This study has been debunked for a while; I saw a PBS frontline program in May that cast substantial doubt upon the veracity of Wakefield's findings.
http://www.pbs.org/wgbh/pages/frontline/vaccines/view/
As mentioned in the above program, dozens of studies have already failed to duplicate Wakefield's findings. Essentially, he blamed autism on a mercury-base preservative that was found in vaccines administered to babies. Even though there was no proof that this preservative had anything to do with autism, manufacturers ceased to use it in vaccines, but this only caused the anti-vaccine to go hypothesis hunting once more.
Your /. name is Ismellpoop, you didn't vaccinate your kids, and you tried explaining this foolishness. I am Jack's complete lack of surprise.
Living With a Nerd
What really amazes me about this business is the behavior of the mainstream media in relation to the development of this 'story' in the first place.
Wakefields paper was just a collection of 12 anecdotes - meaningless in any clinical sense. He's clearly an idiot and should simply have been struck off and ignored.
You don't need to be an expert to work out that MMR and autism are both fairly common, and to find some cases of kids that have both is not that unusual - certainly not enough to start the newspaper and TV frenzy that occurred. That the media decided not to ignore him and tried instead to promote the scare, is to their great shame.
What is also incredible is the fact that that media deliberately ignored studies that proved no connection at all between MMR and autism.
It's appalling that this effort to boost ratings almost certainly cost the lives of infants and probably still does.
Generally, when the numbers are bigger...
...the conspiracy must be bigger?
it is hard to quantify, but the amount of idiots of didn't get their kids vaccinated because of this guy's "research" probably resulted in many unnecessary deaths of children. and this includes children who were vaccinated: an effective vaccine relies on "herd immunity". if enough kids are resistant to say, whooping cough, whooping cough can't get a leg up into a given population. but if enough aren't immune, the disease gets a certain amount of circulation in the community, and is able to try to infect many more kids. eventually, it is able to infect kids of parents who dutifully got their kids vaccinated (since for every vaccination, many vaccines don't take), and eventually, it is able to kill many kids
oh, and someone infect jenny mccarthy with whooping cough, that ignorant bitch. let her know what her "advocacy" really means
intellectual property law is philosophically incoherent. it is your moral duty to ignore it or sabotage it
The mortality of measles is about 0.3% - 3 kids in 1000 that contract it will die. Your sample size simply means nothing. That's why you leave epidemiology to the experts and don't recklessly endanger not only your kids but everyone they come in contact with by refusing vaccination. In my opinion, it should simply be mandated by law. Parents refusing to vaccinate are clearly unfit for their role, their kids are better off if their asshat parents get thrown into the slammer and the kids set up for adoption.
Ubi solitudinem faciunt, pacem appellant.
Thimerosal is not mercury. It is a compound with mercury in it with low bioavailabity.
That's like not eating salt because you're afraid of the chlorine molecule it contains.
There are countless pages out there discussing the dangers of chlorine, that doesn't make salt a hyper-deadly toxin.
Trolling is a art,
So a completely different vaccine has the same effect: autism! I have another explanation that is much more plausible: people who tend to believe in wild conspiracy theories have a 3 times higher risk of having children with autism.
Emphasis mine.
Vaccination acts as a sort of firebreak or firewall in the spread of the disease, slowing or preventing further transmission of the disease to others.[3] Unvaccinated individuals are indirectly protected by vaccinated individuals, as the latter will not contract and transmit the disease between infected and susceptible individuals.[2] Hence, a public health policy of herd immunity may be used to reduce spread of an illness and provide a level of protection to a vulnerable, unvaccinated subgroup. Since only a small fraction of the population (or herd) can be left unvaccinated for this method to be effective, it is considered best left for those who cannot safely receive vaccines because of a medical condition such as an immune disorder or for organ transplant recipients.
The more people who opt out of vaccines, the greater the likelihood of these diseases making a comeback. That's why you've never seen the measles or the mumps.
https://secure.wikimedia.org/wikipedia/en/wiki/Herd_immunity
You are entitled to your own opinions, not your own facts.
From the article you link to...
The WHO says the outbreak occurred when some of those who had received the oral polio vaccine excreted a mutated form of the virus which infected those who were not immunised.
Emphasis mine.
You are entitled to your own opinions, not your own facts.
Sadly that isn't the case. Their kids become petri dishes for the viruses to grow and mutate in. Eventually, a virus that could have been prevented with a vaccine, has now evolved into one that can't.
How about I piss in your cornflakes? What's the problem it's not piss it just has a small amount of piss in it.
If you were to bind the piss with the cornflakes and create a new, safe and tasty molecule then I would try it.
They drink recycled urine on the space station, btw.
Trolling is a art,
You do realize that the rate of autism, i.e. the number of cases per 1,000 people, is also increasing? In other words, when accounting for increasing in population, there is a rise in the rate of autism.
That is the question people are trying to answer. Personally, I think a large chunk of it is probably explained by higher rates of diagnosis. More kids who wouldn't have been label autistic back in the day are now being labeled. Whether it's really justified or not, is another question.
Measles deaths worldwide fell by 74% between 2000 and 2007, from an estimated 750,000 to 197,000. Do you know anyone who died from malaria (1,000,000/yr), yellow fever (200,000/yr), aids (1,800,000/yr), lukemia (600,000/yr), flu (500,000), rabies (55,000)?
I threw away a few mod points to reply so I hope it sinks in that after a 74% drop in measles deaths it is now as harmless as yellow fever, if it drops by a further 74% it will be as harmless as rabies.
And did you exchange a walk on part in the war for a lead role in a cage? - Pink Floyd.
Even if thimerosal were mercury, it has no relevant place in the anti-vaccine argument since there was no correlating decline in autism cases when it was removed from children's vaccines. Autism diagnoses have continued to rise in the wake of the questionable thimerosal ban and the rising numbers of the unvaccinated, which all but confirms that thimerosal was nothing more than a needless distraction.
Anti-vaxxers still bring out the ghost of thimerosal because having an opportunity to name drop "mercury" makes them appear to be more serious and educated than they actually are. The first step in reintroducing rationality and logic to an anti-vaxxer is to nip that particular argument in the bud.
I completely agree with you and I like the salt analogy, but I wouldn't even give them that much leeway.
Hey, look,it's a moron who's out of date and hence peddling the old junk science.
Mercury has not been used in vaccine preservation since 1999, you moron. Because of idiots like you claiming the mercury was causing autism (Mercury does not cause autism, it causes quite recognizable mercury poisoning, which is much closer to insanity than autism), the companies stopped using it.
And yet, hey, look, autism? Not gone down.
If corporations are people, aren't stockholders guilty of slavery?
#1 The growth rate of autism also correlates to a decrease in diagnoses of mental retardation. Special education and allied health therapies have improved in the past few decades such that we can more accurately differentially diagnose various types of developmental disorders. #2. And the increased focus on early intervention means we can now mitigate the severity of developmental disorders so that someone born with autism may not necessarily be severely mentally retarded as they would have been in the 1970s or '80s. #3. Finally, we've become so convinced that there is an "epidemic" that there is more money and services available for autism spectrum disorders relative to other developmental disabilities, so that any kid who displays any autistic-like qualities is likely to be identified as ASD because it opens a lot of doors for getting services that might not be otherwise available.
That's not to say it isn't increasing, but the numbers may not be saying what you think they are saying.
There's a perfect xkcd for my sig but I'm too lazy to look it up. sudo someone go find it.
As a climate scientist, I thought about this comparison.
But we're not throwing Wakefield to the wolves because he was wrong. Lots of scientists are wrong, it's okay. And it's not because he spoke with bias for a hypothesis he believed in. That's okay too. Wakefield's crimes are 1) deliberately falsifying and modifying data to fit his theory, and 2) doing so for profit without disclosing a conflict of interest.
The East Anglia CRU emails, which I assume are the hotbuttons you're pushing at the moment, show scientists with strong opinions, possibly putting a little spin on their presentations, but there is no evidence that they falsified data or took money under the table for their activities.
Don't knock Jenny. She worked for years at the "MTV Spring Break Live and Biological Research Laboratories". Her extensive research into autism and wet t-shirts is highly respected around the world. She is uniquely qualified to comment on matters critical to public health and matters concerning T&A. I look forward to her next research paper on gravitational wave detection and the structural limits of bikini tops.
It is by the juice of the coffee bean that thoughts acquire speed, the teeth acquire stains. The stains become a warning
There is a problem with letting mornic parents do there own thing. It can (and does) hurt the children of responsible parents too.
There are two main ways for the children of a responsible parent to come down with one of these childhood diseases:
1) The vaccine just "didn't take". It happens. They aren't perfect. However, if EVERYONE was vaccinated, this wouldn't matter, as the disease would be eradicated (or nearly so), and then you don't have to worry about catching it. Instead, kids where it didn't take pick it up from kids whose parents were morons.
2) A child is too young to be vaccinated. These vaccines are not administered at birth, and some of them require several doses before immunity is achieved. It is quite possible to pick up the disease from the child of a vaccination-refusing parent. To top things off, the older unvaccinated child is more likely to survive the disease, while the newborn is quite vulnerable.
Yes, it is possible for the diseases to be transmitted solely among children with failed vaccines or those that are too young to be vaccinated, but those cases are quite rare. Measles was well on the way to being eradicated in the Western World before this clown came along. Imagine what a disaster it would have been if this guy was peddling his quackery prior to the eradication of smallpox or the near-eradication of polio.
Thimerosol (sp?), the trace-murcury-containing preservative you are thinking of, is no longer used in US childhood disease vaccines. Hasn't been for many years. And when it was gone, whadda-know, autism rates didn't drop.
That's an even better example, but I didn't want to use it.
Yeah, you can actually figure out how plausible a scientific position is the more the facts change and people (are forced to) accept the new facts, but then still argue the same conclusion.
And it's not really even the same 'conclusion'. It's past the conclusion. It's the same 'So now that we've figured that out, the thing we should do is...'
If I stand there and argue, on a trip, that we should drive down, say, highway 141 to get to Gainesville, and it's pointed out that highway 141 doesn't go to Gainesville, and so I argue that we should drive down 141 to get some Taco Bell, and it's pointed out that there's a Taco Bell on the actual route to Gainesville, and then I argue that Gainesville is a stupid place to go and we should go to Lawrenceville down 141 instead, and it's pointed out while that's technically possible, that's not a very good way to get to Lawrenceville...
At some point, people really should realize I obviously have a motive to drive down 141, because every single plan I invent involves driving down 141.
Likewise, at some point people need to realize the climate change deniers have some sort of motive to not do anything about climate change. (What that motive is is rather obvious if you look at the funding sources.)
But even if you knew nothing who was funding that, it's clear there is some motive, because every. single. one. of their conclusions is 'We shouldn't do anything', no matter what facts they've decided to finally accept. It might exist, it might not, it might be us, might be the sun or volcanoes, it might be a good thing, it might be a bad thing, whatever it is, we sure as heck shouldn't demand people change their behavior, ever.
Same with the anti-vaccine crowd. First it was mercury in vaccines, then it was this study, now I'm sure some other bogus thing will come up. But every single solution is 'less vaccines'. Actually, if you look real close, you'll see every single solution is 'traditional medicine bad, alternative medicine good'.
People who sit and argue the same 'problem solution' despite the problem constantly changing are dishonest, and not scientists, and people need to stop listening and call them out on it the very first time they do that.
If corporations are people, aren't stockholders guilty of slavery?
Personally, I think a large chunk of it is probably explained by higher rates of diagnosis. More kids who wouldn't have been label autistic back in the day are now being labeled. Whether it's really justified or not, is another question.
Bingo. Not a very popular stance, but I'm guessing it is the closest to the actual truth of the matter. We've expanded the diagnostic criteria of autism spectrum "diseases" to the point of being utterly meaningless. Around 90% of the people I was friends with in the early 90's (before the autism craze) would probably be placed somewhere in the autism spectrum if they were youths today. I, too, would have probably been autistic, or at least "suffering" aspergers. Luckily this was the early 90's and we all just got ADD/ADHD instead.
I am happy that the APA (organizers of the DSM) are planning on removing aspergers from the new addition, in order to force mental health professionals to either diagnose autism or nothing, which might cut down over-diagnosis levels a bit.
When I was first venturing into psychology as a field of study, one of my early professors was very quick to point out that everyone has symptoms of a very large array of listed mental illnesses, but what keeps you from being actually mentally ill is the ability to function normally. If you are capable of having long terms friends, a wife, a steady job, etc.. you probably are not "mentally ill". As "illness" generally (used to be) taken as "an impediment to normal functioning". This isn't saying such modern vogue diseases don't exist, but are VERY overdiagnosed. There are people running around proclaiming aspergers or adult-ADD who have large happy families, well paying jobs with long-term stability, and an active social life, these people are not sick, since they are functioning at a high level.
I'm not sure of all the causes of this largely purely social phenomena; but part of it is the huge pressure pharma exerts on doctors, and the fact that parents want results. If parents, or teachers, aren't happy with little Billy's performance or personality, then they will shop around until someone agrees with them. As a doctor, you might as well diagnose, because if you don't someone else will. My dad this this when I was young (mostly as a political maneuver in a divorce, with a bit of influence from some overworked teachers), he took me to around five doctors until one of them decided I must have ADD, and perhaps some flavor of clinical depression. (without ever actually talking to me).
Another thing is that parents ignore natural variation. Someone I know is trying to get their kid diagnosed with autism because she hasn't spoken by the time she turned 3 years old. While this might be unusual, it isn't unheard of, or even that problematic. It is well within the natural variation of human development.
A patriot must always be ready to defend his country against his government. -edward abbey
Because basing all of your ideas on shoddy research that has been proven to be falsified is never a good strategy, regardless of how much money you have. McCarthy is convinced she knows the cause of her child's autism, and all the scientific evidence (or lack thereof) in the world are not going to convince her to change her opinions. Her mind is pretty closed on this subject I would say. When you have ex-playboy models claiming to have better scientific knowledge of a disease than actual doctors in the field do themselves, it is time to take anything she says with a rather large grain of salt.
"But this one goes to 11!"
Sadly, there's even bigger money in Big Pharma.
Okay. Let's look at this clearly: Big Pharma is a mixed bag of positive and negative. They have undeniably provided products of great benefit to human health. And there is also undeniably many cases of them providing unnecessary vanity products, unintentionally harmful products, and products they knew were harmful or useless which they skewed data to get approved. I have lots of problems with Big Pfizer^H^H^H^H^Hharma.
Junk science is not a mixed bag. At best it causes people to get ripped off buying placebos, and at worst causes significant harm by making people not seek real medical treatment when they need it, or not vaccinate their kids so you get outbreaks of measels or whooping cough that affect not just their children, but the children of people who didn't buy into the junk science.
Please let us not talk about these things as if they are equal. There should be lots of money in legitimate pharmaceutical research and manufacturing, but we should also push to solve the problems with it. The problem with junk science, homeopathy, anti-vaccination movements, etc is the junk science itself.
The enemies of Democracy are