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Scientists Put an End To Smelly Socks

athe!st writes "A new anti-microbial treatment that can make clothing — including smelly socks — permanently germ-free has been developed by US scientists. In a paper published in the American Chemical Society journal Applied Materials and Interfaces, Dr Jason Locklin and his colleagues state that the treatment kills a wide range of dangerous pathogens, including staph, strep, E. coli, pseudomonas and acinetobacter."

42 of 238 comments (clear)

  1. Great... by msauve · · Score: 3, Insightful

    another way to breed resistant strains of dangerous pathogens.

    --
    "National Security is the chief cause of national insecurity." - Celine's First Law
    1. Re:Great... by geekoid · · Score: 3, Informative

      depends on how it works.

      For example, alcohol based hand sanitizers can not be a vector for a 'resistant' germ.

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
    2. Re:Great... by mcsqueak · · Score: 2

      I would not recommend anything alcohol-based to be used with children who's development is still in progress.

      So you're saying I shouldn't be giving my toddler bottles filled with whiskey then?

  2. Only socks? by rednip · · Score: 2

    Hospital bed sheets would be my first use.

    --
    The force that blew the Big Bang continues to accelerate.
    1. Re:Only socks? by capedgirardeau · · Score: 5, Informative

      You need to update your talking points. Bedbugs were either in the process or already resistant to DDT in many areas.

      Please see:
      DDT resistance: once more, with tables and sources

      --
      Wax on, wax off baby!
    2. Re:Only socks? by PCM2 · · Score: 2

      I freely admit I'm pretty ignorant of microbiology but given the choice I'd wager heavily that boiling water is more efficacious than than a chemical treatment.

      We'll agree on "at least as effective," but the problem is that you can't have your hospital staff lounge in vats of boiling water while they deal with patients. It's not like a scalpel where you use it once and throw it into the autoclave. Healthcare workers wear their garments all day.

      --
      Breakfast served all day!
    3. Re:Only socks? by omnichad · · Score: 2

      Mmm...hospital staff soup...

      CORRECTION: hospital Staph soup

  3. Better living through chemicals by Moof123 · · Score: 4, Interesting

    Am I the only one who has grown cautious of putting chemicals on my skin, in close contact, for many hours of the day? We'll either end up with a super bug or foot cancer...

    1. Re:Better living through chemicals by geekoid · · Score: 3, Insightful

      You don't have any air contact your skin? no moisture? no cloths? hmm, maybe you should narrow it down from 'chemicals'?

      --
      The Kruger Dunning explains most post on /. http://en.wikipedia.org/wiki/Dunning%E2%80%93Kruger_effect
  4. Ask the microbes by FranTaylor · · Score: 2

    Why they don't want to live in the clothing, maybe they know something you don't.

  5. Re:Hmm... by Literaphile · · Score: 5, Funny

    Let's see, contribute to the creation of a superbug, or wash my fucking socks? Decisions, decisions...

    You have socks just for fucking?

  6. Re:I really really need this by Lifyre · · Score: 2

    There is a time tested method to solve this problem. Burn them and buy footwear that doesn't get ruined the first time you wear it in a winter storm.

    --
    I'll meet you at the intersection of "Should be" and "Reality"
  7. Yes, Great... by Anonymous Coward · · Score: 3, Informative

    What makes you think microbes cannot be resistant to alcohol? Some microbes literally shit alcohol.

    Unicellular life has a much easier time evolving than we do. Lining up 3 trillion cells to work together at all amazes me, & I'm doing that right now!

    1. Re:Yes, Great... by buback · · Score: 3, Insightful

      Since alcohol literally dissolves cell membranes, I'd be pretty impressed if they evolved past that impediment. Also remember that those bacteria that 'shit' alcohol are eventually killed off by all that 'shit'. That's why you can't brew vodka, but distill it instead.

    2. Re:Yes, Great... by dr-suess-fan · · Score: 2

      FYI, it's yeast (a member of the fungi kingdom), not bacteria. Bacteria can spoil a good brew.

    3. Re:Yes, Great... by Ossifer · · Score: 5, Informative
    4. Re:Yes, Great... by pclminion · · Score: 5, Insightful

      Some microbes literally shit alcohol.

      Such organisms consume food and excrete alcohol until the ambient concentration is too high for them to tolerate any longer. After years of selective breeding some yeasts have been produced that can tolerate up to about 22% ABV but it doesn't seem to go much higher than that.

      How many days could you take a shit in your living room until you could no longer tolerate it? I doubt any amount of evolutionary pressure could enable you to swim in a diarrhea swimming pool.

    5. Re:Yes, Great... by Cryolithic · · Score: 2

      Mod Parent Up! God I love me a good lambic! He's GP is right though, *most* of the time, bacteria in your fermentation process is not a good thing.

    6. Re:Yes, Great... by ImprovOmega · · Score: 3, Insightful

      Because it would have to evolve a plastic coating that still magically performed all of the functions of the original cell membrane. It would be kind of like saying why can't human evolve a plastic coating over their lungs to defend against inhaling acid fumes. You would block what was killing you at the expense of ...well...killing you in a different and horrible way.

    7. Re:Yes, Great... by adolf · · Score: 2

      How many days could you take a shit in your living room until you could no longer tolerate it? I doubt any amount of evolutionary pressure could enable you to swim in a diarrhea swimming pool.

      Perhaps not evolutionary pressure, but I for one would be perfectly happy to swim some laps in a diarrhea swimming pool for the correct amount of monetary pressure.

      Which leads to an interesting philosophical question: Does this mean that I am better-adapted than yeast, or does it mean the opposite?

    8. Re:Yes, Great... by Ossifer · · Score: 2

      My GP says I should not drink so much beer.

    9. Re:Yes, Great... by mortonda · · Score: 2

      I had a navy friend who was, fortunately, the 2nd smallest person on the ship. The guy who beat him out for being the smallest had to dive into the septic tank to unplug the drain. Evolutionary pressure, no. Navy pressure, yes.

    10. Re:Yes, Great... by thisnamestoolong · · Score: 2, Funny

      How many days could you take a shit in your living room until you could no longer tolerate it?

      Well, I started watching Transformers that one time, so I guess it would be about 15 minutes...

      --
      To the haters: You can't win. If you mod me down, I shall become more powerful than you could possibly imagine
    11. Re:Yes, Great... by buback · · Score: 2

      And if it did survive, it would have to evolve an entirely new way to infect cells. it would become so different from what we see now that it might not even "want" be infectious anymore.

    12. Re:Yes, Great... by Odinlake · · Score: 2

      What makes you think microbes cannot be resistant to alcohol? Some microbes literally shit alcohol.

      You shit shit, but can you live in shit???

    13. Re:Yes, Great... by sjames · · Score: 2

      Some microbes literally shit alcohol.

      And in spite of that, they eventually poison themselves in a closed environment. That's why you can only get proof so high without distilling or fortifying in spite of centuries of effort by brewers to improve their yeast.

      Certainly single celled life can evolve surprising levels of resistance to various noxious environments, but there are limits. At the edge of those limits, extremophiles must go to such extremes of adaptation that they can no longer compete in a less hostile environment.

  8. Re:Thalidomide by Verdatum · · Score: 2

    It's really hard to make socks that fit on guinea pigs.

  9. How it works by Anonymous Coward · · Score: 5, Informative

    I normally don't post on slashdot, but since this is related to my field (I am a chemist) and there have been a lot of comments about how bad this must be because of the possibility of building resistance, I felt obligated to clarify this after looking into it.

    As far as anti-microbial substances work, this is about as simple as it gets. All bacteria have cell membranes consisting of a lipid bilayer - it's basically two layers of negatively-charged water-loving stuff attached to a fatty part in the middle that stays away from water. This treatment uses a polymer that can pass through the cell membrane, with positively-charged bits making it inside the membrane. The positively-charged parts on the polymer attract the negatively-charged parts on the membrane and cause it to come apart enough for the cell to die.

    Many other antibiotics are based on small molecules that interrupting some metabolic process of bacteria. Bacteria develop resistance by making enzymes that will break down these small molecules once inside the cell. This new method attacks the outside of the cell directly, not something inside the cell. It wouldn't be impossible for bacteria to develop immunity to this, but it would be comparably very improbable.

    1. Re:How it works by ColdWetDog · · Score: 2

      No wonder you don't normally post on Slashdot. You demonstrate a reasonable comprehension of the concepts discussed and furthermore can explain your thoughts in perfectly comprehensible English.

      This is a pretty lonely place for folks like you.

      --
      Faster! Faster! Faster would be better!
    2. Re:How it works by migloo · · Score: 2

      Pardon my total ignorance but, presuming human skin cells also have a membrane, why aren't they also destroyed in the process?
      It reminds me of this old mystery (to me at least) of why the stomach does not digest itself.

  10. Re:Hmm... by Abstrackt · · Score: 4, Funny

    Let's see, contribute to the creation of a superbug, or wash my fucking socks? Decisions, decisions...

    You have socks just for fucking?

    You don't?

    --
    They say a little knowledge is a dangerous thing, but it's not one half so bad as a lot of ignorance. - Terry Pratchett
  11. Cookie Absent by Hatta · · Score: 2

    47 comments and no one noticed that the link was broken? Sure there's a BBC link, but it tells you exactly nothing. Doesn't even tell you what it is. I know slashdotters seldom read the articles, but come on.

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    Give me Classic Slashdot or give me death!
  12. Re:Great! by newcastlejon · · Score: 2

    Sorry, but I was just talking about socks there. When it comes to white coats, why not try paper? You could impregnate it with this chemical and recycle or just throw into an incinerator after use.

    --
    If God forks the Universe every time you roll a die, he'd better have a damned good memory.
  13. Re:Resistant Germs by ImprovOmega · · Score: 2

    Depends on how it works. If it's a vector that some germs can survive, like with antibiotics, then there's a chance for a new generation to be born resistant to it. If it's a physical vector that is incompatible with germ life like how alcohol basically dissolves bacterial cell membranes, then no.

    It's like how the human population can become resistant to a particular virus, but no one is resistant to a bullet through the heart.

  14. Just use Ammonium Alum by Twinbee · · Score: 3, Interesting

    Okay here's a semi-secret which shouldn't be so secret. I use something called PitRok Crystal Deodorant (perhaps try this if you're US based), but any Ammonium Alum based deodorant will be good. It's meant for the armpits, but I find it works good on feet too. 5 stars on Amazon.co.uk by almost everyone including me.

    I only wish I knew about this sooner. It's completely odorless and nonsticky, which is great, but also lasts over a year (you wet its hard crystal tip and apply). Anybody who benefits from this, feel free to buy me a beer or 10 according to how generous you feel.

    --
    Why OpalCalc is the best Windows calc
  15. Re:Working link to actual paper by slew · · Score: 2

    And since nobody probably will click on that link either, here's a convenient summary

    Antimicrobial copolymers of hydrophobic N-alkyl and benzophenone containing polyethylenimines were synthesized from commercially available linear poly(2-ethyl-2-oxazoline), and covalently attached to surfaces of synthetic polymers, cotton, and modified silicon oxide using mild photo-cross-linking. Specifically, these polymers were applied to polypropylene, poly(vinyl chloride), polyethylene, cotton, and alkyl-coated oxide surfaces using solution casting or spray coating and then covalently cross-linked rendering permanent, nonleaching antimicrobial surfaces. The photochemical grafting of pendant benzophenones allows immobilization to any surface that contains a C–H bond. Incubating the modified materials with either Staphylococcus aureus or Escherichia coli demonstrated that the modified surfaces had substantial antimicrobial capacity against both Gram-positive and Gram-negative bacteria (>98% microbial death).

    For folks not in the "know", the basic anti-microbial technique is described in this wiki page.

  16. Re:Thalidomide by ColdWetDog · · Score: 2

    Most men's 9-12 socks will cover a guinea pig almost perfectly.

    You know this for a fact, do you? Why exactly is that?

    --
    Faster! Faster! Faster would be better!
  17. This stuff is rather terrifying. by Chardansearavitriol · · Score: 2

    And its been bothering me. I mean have you seen those hand gels people are always slathering on? They seem to forget the .1% that it doesnt kill. Its like, congrats, you just made your hands a cess pool by removing all the competition a microbe that is already resistant to our best efforts would normally have! The only thing that nears that level of stupidity would be preemptively dosing all our herd animals with anitbiotics by default. But thats so insanely reckless that theres no way wed ever allow it. ...We do? Oh. Thats not good. :/

  18. What about wool? by casi0qv · · Score: 2

    Wool does this naturally.... it's microscopic physical structure is such that bacteria has a difficult time attaching to it physically. When I switched to wool socks I permanently eliminated smelly feet, and they're much more comfortable even in hot weather. Once again, scientists develop a "novel" solution to a problem nature solved much more elegantly long ago. Wool literally evolved for the explicit purpose in which humans use clothing for: keeping mammals comfortable and healthy in a wide range of climates... and it has a complicated structure that gives it unique properties to this end that have yet to be replicated by synthetics.

  19. Re:Panties Anyone? by Anonymous Coward · · Score: 2, Funny

    Faster than anyone around here will.

  20. Alcohol-resisting bugs by DrYak · · Score: 2

    I'd be pretty impressed if they evolved past that impediment

    - Mycobacteria (as those causing Tuberculosis) have thick reinforced waxy cell walls, which can withstand alcohol, for example.
    - P. Aeruginosas also protect themselves (polysaccharids and biofilms) and have evolved to be able to digest quite a lot of organic compound. They'll resist alcohol, and try drinking it too.
    - not a living bacteria, but lots of bacterial spores can withstand a crazy vast amount of abuse, and stay unharmed (that the whole point of spores).

    And for whatever other physical hard-limit you may dream of (and which should effectively kill most of the regular bacteria), there is always bound to exist some obscure extremophile able not only to survive, but thriving in these extreme conditions.

    --
    "Sufficiently advanced satire is indistinguishable from reality." - [Tips: 1DrYakQDKCQ6y52z6QbnkxHXAocMZJE61o ]
  21. Ah, homebrew.... by LongearedBat · · Score: 2

    When friends taste my homebrew, they sometimes ask me how I got the alcohol in there. I tell them that the yeast eats the sugars, pisses alcohol and farts carbon dioxide. For some reason, that I can't fathom, they loose their appetite for my brew at that point.