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Adrenaline May Damage DNA
Thelasko writes "Ever wonder why heads of statetend to age twice as fast as the rest of us? New research shows that adrenaline may damage DNA, potentially accelerating aging."
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stress causes you to age...
Go figure!
What does adrenaline have to do with heads of state? I mean unless you're Gaddafi and on the run from rebels.
I thought it was a common sense that any physical, mental or biological (food) stress can lead to DNA damage and wear out.
If adrenaline causes rapid aging enough that presidents seem to age ten years for every four in office, then how does one explain professional athletes who compete (or at least practice) almost every day for 10-20 years and come out of it looking, if anything, young for their age?
Green skin, gigantic muscles, and torn clothing.
"Well, good luck finding a judge that doesn't run a bestiality site."
I have a feeling it is more about consistant stress rather then extreme bursts. I have a feeling the aging comes more from a stress scale on an 6 of 10 24/7 for 8 years moreso then a burst of addrenaline at a 9 of 10 twice a day for 2 years. I also have to wonder if it is unused adrenaline, when an adrenaline burst is caused by say a granade going off 10 feet, that burst is used to help you run/jump/dive etc... When you are stressed out in a meeting, all it can do is make your heart race, mess with your breathing etc... maybe that energy turning inwards is what causes the damage. So people who can spend more time exercising, shouting etc... when under stress, take less damage then ones who have to sit at a desk smile and pretend they have things under control.
That's easy: they get more exercise than a lot of civilians; there's a funny kind of order to the military that gives someone punctuated stress and relaxation instead of constant stress; and those guys who move up the chain are often just naturally gifted at remaining calm and dealing with what would be considered stressful conditions.
I think you may have the wrong picture, unless Steve Jobs has turned into Norse Mythology. Honestly, I don't want to acknolwedge the existence of iDin, which is 30% thinner and lighter than Odin
This is my signature. There are many like it, but this one is mine.
...die young.
If this were true in all cases, people like me would be in trouble. I run 50+ miles per week and the runner's adrenaline high is a part of my daily life. However, it has to be balanced with the benefit of aerobic exercise: http://www.natap.org/2011/HIV/081911_03.htm That said, I'd imagine most heads of states don't put in those kind of miles, and the CNN article (mostly about Obama) is far from scientific. "Looking older" has shit to do with overall health in many cases. However, the study seems to imply chronically elevated adrenaline levels--and athletes have anything but. Catch us before or after a workout, and many of us* are some of the most mellow people you could meet (because the stress relief offered by heavy exercise is a hell of a boon). Personally, I think that's the key that many people who "read" this article will miss: stress keeps adrenaline *chronically* elevated.
My plan of hiding in my house and doing nothing exciting or stressful ever is working out perfectly.
I'll trust Starfleet medical on this one.
that image has been around since.. well since 04. i've seen it before.
the rumors that steve has / had AIDS predate that image.
it's very likely just a shoop. his horrid appearance over the majority of the past decade has likely only been due to cancer, not AIDS -- and we know for sure he had the former. I don't know what the outlook is for someone with AIDS *and* cancer, but I have a feeling living for 7 more years past the prognosis would be pretty damn miraculous.
... still waiting for this free-as-in-beer free beer I keep hearing about.
That being alive increases the likelihood of death.
Never happened. True story.
Adrenaline may do some damage to your DNA. But nothing like what the bear will do to it if it catches you.
Have gnu, will travel.
Not too much adrenaline in this here basement ....
I'm not a lawyer, but I play one on the Internet. Blog
If you are going to leak something, at least make sure you don't have the test result date be two years before the lab doing the testing operated under that name and offered their services to the general, non-porn-industry public.
Just "gittin-r-done," day after day.
If it can be scientifically proven that stress causes premature aging, will workplace stress become the subject of OSHA regulations and workman's comp litigation?
So now my adrenal glands are going to be required to carry a warning label?
I browse on +1 so AC's need not respond, I won't see it.
I mean, didn't Star Wars teach you anything? It is a sign of the dark side–all your choices, they affect the flesh, rotting it, as the dark side rots you from within.
We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
I think you may have the wrong picture, unless Steve Jobs has turned into Norse Mythology. Honestly, I don't want to acknolwedge the existence of iDin, which is 30% thinner and lighter than Odin
The fun thing is that I read this wrong as Idun, who happened to be the norse godess who watched over the golden apples that made the gods immortal (http://en.wikipedia.org/wiki/I%C3%B0unn)
Not saying it's real but someone like jobs could easily afford to pay his way in if he wanted their services.
AFAIU
a) Adrenaline was not involved in this experiments
b) no word that the compound use directly attacks the DNA, but only blocks pathways.
That is interesting and makes sense. Evolutionary stress was a mechanism which was active only in emergency situations to provide all resources to muscles and movement. In this terms reducing accumulation of unwanted substances in cells (e.g. oxidants) would have never payed off, especially if your maximum age was limited due to other things.
From linked summary:
In the study, mice were infused with an adrenaline-like compound that works through a receptor called the beta adrenergic receptor that Lefkowitz has studied for many years. The scientists found that this model of chronic stress triggered certain biological pathways that ultimately resulted in accumulation of DNA damage.
. . . burns those little DNA strands twice as fast.
Better to live large and die young that to live small and suffer long.
Note quite. Spock magics up an apparently adrenaline-based serum that undoes the rapid aging that some radiation exposure caused in that particular episode. As far as adrenaline itself is concerned, McCoy only says it was used as a radiation treatment in the past, and might be part of a cure for their predicament.
The cure for rapid aging (or late youth) is the transporter (1, 2, 3), psychic magic (4, 5), or nothing (6).
I think I've found all or almost all the episodes that deal with *rapid* age changes. The Bashir episode is questionable, as the aging only occurred in his mind. I can't think of any relevant Voyager or Enterprise episodes. Q's kid ages rapidly for Janeway, but that's sort of to be expected.... There are several episodes that take place partly in the future (the end of Enterprise; the DS9 episode with old Jake Sisko; the end of TNG; the end of Voyager; the icy planet crash landing episode of Voyager; Time's Arrow, kind of--Data's head at least ages 500 years in the course of the episode...), but those don't constitute rapid aging. Picard's hand ages rapidly in Timescape, but that's just one part of his body and doesn't require a "cure" like the other episodes I listed.
If I've missed any (even questionable ones), let me know :).
I had life circumstances that stressed me beyond belief. I'm talking 24/7 constant worry and dread to extremes I've never felt in my life for over 2 months straight. Shortly after I noticed I started balding and I've always had a full head of hair. Yes, it could be just a coincidence but I've read there is such a thing as stress related baldness and if it's short-term hair will usually return. Also, this stressful episode of my life is over but I feel entirely burnt-out as a result.
I exercise and try and eat right, and I can still do my workouts and feel good while working out, but outside of that I feel I have energy for just about nothing. I've read about adrenal fatigue and it sounds like what I have but I've read this is not a recognized medical condition thus there is no treatment.
They say stress ages the body, well if true I feel like I aged a year in a span of a month. It was absolutely horrible. Anyway, I feel like a shell of my former self and I'm concerned I'm not going to bounce back.
You must be new here.
In Russia,mthe anecdote applies *you*! :)
hawk
If you are in Space, what is aging?
I am in space, and I am aging.
No need to invoke epinephrine ("adrenaline") here, nor "DNA damage". Another stress hormone, cortisol, is already well understood to be the major link between stress and adverse health effects.
They've known for a long time that Adderall (specifically its dextro-amp component) is mutagenic, especially if taken before, during, and shortly after puberty; they've known the changes in nucleic acid sequences accounting for this have to do with noradrenaline and associated compounds (pre-metabolites, synthesis, etc). To make matters worse the damage is passed on to offspring. Adderall babies will be an interesting problem in upcoming years.
. None of the astronaughts tuned their clocks in relation to the rotation of the moon when they landed upon the moon.
Wow, you got me there. I guess maybe the governments on the moon haven't set official time zones yet, or something?
Trivial irrelevant studies. Living causes death as an outcome.
Leslie Satenstein Montreal Quebec Canada
No.....running at a faster pace causes you to age, and therefore we know adrenalin makes you pump blood faster...hence why this would seem as the reason.
Any drug that makes your metabolic rate run faster makes you age faster, as the degeneration is quicker then the regeneration, unless you take steroids or gh or other know drugs to counter degeneration, you will age faster, but take gh, with adrenalin.....you end up with no signs of aging.