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Scientists Developed Artificial Structures That Can Self-Replicate

First time accepted submitter mphall21 writes "New York University scientists have developed artificial structures that can self-replicate, a process that has the potential to yield new types of materials. In the natural world, self-replication is ubiquitous in all living entities, but artificial self-replication has been elusive. The new discovery is the first steps toward a general process for self-replication of a wide variety of arbitrarily designed seeds."

32 of 127 comments (clear)

  1. Another step by mysidia · · Score: 3, Interesting

    Towards Grey goo.

    Or big nations making mechanical viruses as weapons, and ultimately... those creations at risk of being turned against their creator through malfunction, hackers, or worse.

    1. Re:Another step by ihaveamo · · Score: 4, Insightful

      Already happened. Except it's pink goo. And it's us.

    2. Re:Another step by interkin3tic · · Score: 3, Insightful

      And you getting a better computer is just one more step toward skynet.

      Or big nations making artificial intelligence as weapons, and ultimately... those creations at risk of being turned against their creator through malfunction, hackers, or worse.

      Slashdot: news for technophobes. Lay off the LSD. Every technology can be abused. You're suggesting we shouldn't look into self-replicating structures because one day far down the road, some evil government agency MIGHT use it to unleash a horde of nanobots which will destroy the world? That's absurd.

    3. Re:Another step by Oxford_Comma_Lover · · Score: 3, Insightful

      The greater concern is that the technology will be used without understanding of the consequences. The Replicators in Stargate, for example, emerged from an experiment in which a childlike intellect taught its toys to make more of themselves. Research into self-replication, while reasonable, is not without nightmare scenarios or significant potential drawbacks.

      The cockroach is one example of such an experiment. Who is to say that in time, we will not create an example capable of out-competing us for some natural resource? So it is not without risk to experiment in self-replication. You can limit the risk, of course. Until someone makes the wrong kind of mistake at the wrong time. Kind of like researching Level 4 biohazards in a major population zone. If nobody does something dumb or protocols require fifty dumb things to happen at once for a problem and no massively unexplained events occur, it works just fine.

      --
      -- IANAL, this isn't legal advice, and definitely isn't legal advice for you. Also, Squee!
    4. Re:Another step by EdZ · · Score: 2

      Or rather, it's green goo (with life by volume being predominantly chlorophyll-using). Note how the entire planet has not become a single lump of homogeneous cells. Considering why this is will quickly tell you why the Grey Goo scenario is rather silly. If there is any danger from unrestricted replication, it would be more akin to the introduction of a foreign species into an ecosystem. However, unless whoever builds aforementioned unrestricted (and pointless: unless the replicator itself is useful, why would you design it to only replicate more of itself rather than making something useful?) replicator designs it almost entirely out of Carbon, Hydrogen, Oxygen and Nitrogen, it would either be bought to it's knees without freely available Silicon and rare-earths, or simply not compete with organic life and form a parallel ecosystem.

    5. Re:Another step by ancienthart · · Score: 2

      Except that StarGate is fiction.
      It'd be a pretty shitty story that went "Thousands of years ago, a civilisation created a self-replicating machine. It escaped into the environment. And was promptly turned back into raw silicon dioxide by the first bacteria that found it tasty."

    6. Re:Another step by ericartman · · Score: 2

      Ugly bags of mostly water

  2. Good news... by GuJiaXian · · Score: 5, Funny

    ...they've created an artificial structure that can self-replicate. The bad news is that it's Ice-9.

  3. Uh oh by Hsien-Ko · · Score: 2

    If this thing self-replicates to resemble a Robert Patrick, we're all screwed.

    1. Re:Uh oh by Fnord666 · · Score: 3, Funny

      I for one would like to welcome our self-replicating overlords.

      Especially if they look like Kristanna Loken

      --
      'The tyrant will always find pretext for his tyranny.' - Aesop's Fables
    2. Re:Uh oh by PopeRatzo · · Score: 2

      Especially if they look like Kristanna Loken

      The Academy snubbing her for an Oscar for her amazing performance in Uwe Boll's 2006 epic In the Name of the King (Dungeon Seige) is a travesty that I still have not gotten over. They gave it to that boring Helen Mirren for The Queen that year, and while Helen Mirren is decent, and certainly bangable, she doesn't have Kristanna Loken's acting chops. However, I understand Mirren can pick up quarters with her...you know, so I can see how the Academy might be swayed.

      Regarding the self-replicating structures, affiant sayeth not.

      --
      You are welcome on my lawn.
  4. self-replication is easy... by catbutt · · Score: 2

    ...if you are allowed to have complex raw materials.

    Fire self replicates. Fallen-down dominoes self-replicate. The line between "chain reaction" and "self replication" is very blurry.

    1. Re:self-replication is easy... by Co0Ps · · Score: 3, Interesting

      Yes.. your argument applies to literally everything though... so dismissing anything as "just a chain reaction" is basically saying that "this is just a subset of the universe." In other words your argument is true but pointless. Disclaimer: I assume that the universe is a deterministic state machine.

    2. Re:self-replication is easy... by Kozz · · Score: 4, Informative

      ...if you are allowed to have complex raw materials.

      Fire self replicates. Fallen-down dominoes self-replicate. The line between "chain reaction" and "self replication" is very blurry.

      I don't think it's as blurry as you'd make it out to be. Fire and falling dominoes are instances of entropy , quite the opposite of what these scientists are after, I believe.

      --
      I only post comments when someone on the internet is wrong.
    3. Re:self-replication is easy... by Jane+Q.+Public · · Score: 2

      "which is in all honestly quite pointless."

      What's your point?

    4. Re:self-replication is easy... by Jane+Q.+Public · · Score: 2

      What the other poster said. Exactly. Self-replication, the seeming creation of greater complexity out of less complexity, is only possible in open systems, that can get information or energy from elsewhere.

      The universe, being (as far as we know) a closed system, therefore, can only allow it in relatively small and isolated regions, precisely because of entropy. Local entropy can go down (self-replication) but inevitably it adds to the overall entropy of the universe.

    5. Re:self-replication is easy... by julesh · · Score: 2

      Life is an example of negative entropy, i.e. a process that absorbs free energy from its environment and uses it to work against entropy by making a small section of that environment more ordered. That the absorbtion of energy creates more entropy than the localised reduction is given, but it doesn't detract from the usefulness of this observation. I imagine any realistic self-replicating machinery will have the same attributes. Fire and falling dominoes, however, don't.

  5. Artificial? by Hentes · · Score: 5, Insightful

    They took DNA, a natural structure that can replicate, and modified it without breking that property. I wouldn't call it artificial self-replication.

    1. Re:Artificial? by DigiShaman · · Score: 2

      At what point will we have a text based programming language that will compile the results into a DNA sequence? Coding the next plague wouldn’t be such good idea. Because you know, there are assholes in this world that would do just that.

      --
      Life is not for the lazy.
    2. Re:Artificial? by Chris+Burke · · Score: 2

      Fair enough. That's true, but they modified it a lot, creating a structure that as far as we know doesn't exist in nature. It replicates without any of the normal cellular chemistry that makes it happen naturally including enzymes, which separates this from the Polymerase Chain Reaction technique for DNA amplification someone mentioned below. It also allows them to replicate structures other than proteins composed of amino acids defined by the normal base pairs.

      They even fabricated the DNA they used, so it's technically artificial. In a more meaningful sense, maybe it's not completely artificial. Not to the extent of things we might make in the future. Still, I don't think it's complete hyperbole for a headline about a significant step.

      --

      The enemies of Democracy are
    3. Re:Artificial? by Daniel+Dvorkin · · Score: 2

      At what point will we have a text based programming language that will compile the results into a DNA sequence?

      Automated production of short sequences is a well-established technology; Google on "custom oligonucleotide synthesis" and "custom gene synthesis" and you'll get links to a bunch of companies that will be happy to manufacture just about any sequence you want. Assembling an entire genome is harder, but not that much. So the answer to your question is pretty much "we're already there."

      Nobody's built any superplagues base pair by base pair yet, and honestly, I think it's not particularly worth worrying about. If unleashing a killer epidemic were your goal, it would probably be easier to take some common, virulent but not terribly dangerous pathogen (say, a rhinovirus) and screen mutants for morbidity and mortality; or alternately, take one of the great plagues of the past (say, smallpox) and alter it to slip past current vaccines.

      --
      The correlation between ignorance of statistics and using "correlation is not causation" as an argument is close to 1.
    4. Re:Artificial? by julesh · · Score: 2

      Erm... no. They took DNA, a natural structure which is half of a system that can replicate (the other half being a collection of enzymes that can transcribe the DNA to RNA, and a ribosome that can take RNA templates and make enzymes, some of which can produce more DNA or ribosomes) and rearranged it into an entirely new structure that doesn't require the assistance of a ribosome to replicate itself.

  6. From a Biological Perspective We're Probably Fine by RobinEggs · · Score: 5, Interesting

    I see the first five responses were about science fiction scenarios in which nanomachines destroyed human life.

    All that's really necessary to prevent the machines from getting out of control, however, is to design them with some chemical dependencies. If it needs gold or it can only incorporate carbon from certain uncommon molecules to grow then it can't get very far. Plus, natural selection will be true in part with any self-replicating thing. If they get out they'll have to struggle for resources just like any other form of life. There isn't any reason to automatically assume they'll be better at it simply because they're artificial.

    There are even scenarios in which it might be nice to design nanomechanical organisms with the express purpose of setting them free; I'd sure like an organism that got along by fixing the carbon in carbon monoxide, the ozone in smog, and the nitrogen in nitrogen dioxide to replicate itself. It could make Los Angeles habitable again, and its reproduction would be limited to the rate at which we produce pollutants.

  7. First application: catalog item 2418-B by ConsistentChaos · · Score: 4, Funny

    The Remote Self-Replicating Robot Explorer Probe. Be afraid.

    1. Re:First application: catalog item 2418-B by Tubal-Cain · · Score: 2

      We'll be fine as long as we don't set replication's priority at 999, we should be fine.

  8. Re:From a Biological Perspective We're Probably Fi by erktrek · · Score: 4, Interesting

    I've also heard that the "grey goo" scenario is a bit overstated given that:

    Organisms have already evolved optimal survival strategies over the millennia and if nanobots were made of organic material they would be "prey" to some of these.
    - and -
    The energy requirements for taking on such a task is unlikely to be satisfied in the current environment (especially if made of non organic materials)

  9. stock up on bullets by Joe_Dragon · · Score: 2

    stock up on bullets

  10. How soon before by flyonthewall · · Score: 2

    Moya?

    Self replication of artifices (self repairs..) is what is going to be needed to long term voyages.

    --
    "The avalanche has already started. It's too late for the pebbles to vote." - Kosh
  11. great bachelordoom... by ThorGod · · Score: 2

    Just when I thought I couldn't get any lower as a bachelor...machines go and gain the ability to replicate - I can't even do that!

    --
    PS: I don't reply to ACs.
  12. Re:Sound suspiciously like PCR to anyone else? by julesh · · Score: 2

    Also FTFA:

    no biological components, particularly enzymes, are used in its execution

    So no, not PCR or PCR-like, as such processes require enzymes.

  13. Re:From a Biological Perspective We're Probably Fi by Intrepid+imaginaut · · Score: 2

    Remember though, there is no animal on earth that is superior to a simple rifle. We're quite capable of building a bionuke, intelligence goes to places evolution never would or perhaps could.

  14. Re:A brief rant on scientists and terminology by Chris+Burke · · Score: 2

    You're drawing a line where none exists, and in the wrong place to boot.

    Engineers develop useful, practical things. Things that serve a particular need, that can be made economically, etc.

    Scientists develop things, too, but they aren't as often concerned with the direct utility or practicality of what they develop. For instance what these scientists developed is an ingenious proof-of-concept that could eventually be developed into a practical procedure for replicating materials, possibly by a chemical engineer.

    However scientists also frequently develop practical, useful things. The PCR process you have seen mentioned in this thread is incredibly useful and practical, and was developed by a chemist.

    Sometimes the line gets really blurry, like in the development of a new technology for silicon IC fabrication. The material science and the material engineering are closely coupled and it's hard to say specifically which is which in a given case, outside of edge cases.

    --

    The enemies of Democracy are