Slashdot Mirror


Genetically Modifying Silk Worms For Super Silk

New submitter davidshenba sends this quote from the BBC: "U.S. researchers have created silkworms that are genetically modified to spin much stronger silk (abstract). In weight-for-weight terms, spider silk is stronger than steel. ... Researchers have been trying to reproduce such silk for decades. But it is unfeasible to 'farm' spiders for the commercial production of their silk because the arachnids don't produce enough of it — coupled with their proclivity for eating each other. Silk worms, however, are easy to farm and produce vast amounts of silk — but the material is fragile. Researchers have tried for years to get the best of both worlds — super-strong silk in industrial quantities — by transplanting genes from spiders into worms. But the resulting genetically modified worms have not produced enough spider silk until now. GM worms produced by a team led by Professor Don Jarvis of Wyoming University seem to be producing a composite of worm and spider silk in large amounts — which the researchers say is just as tough as spider silk."

30 of 129 comments (clear)

  1. I, for one, by zoom-ping · · Score: 3, Funny

    welcome our new super silkworm overlords.

    1. Re:I, for one, by martijnd · · Score: 2

      "It's hard to see how a silkworm producing spider silk would have any advantage in nature," he said.

      You sir, are on to something. This researcher is showing a clear lack of imagination.

  2. Why is there any concern about GM silk? by Anonymous Coward · · Score: 5, Interesting

    Inside the article there was a mention that the GM silk could post a threat to the environment.

    Call me dense, but I just don't get it.

    We are not talking about something that last forever or what, we are talking about silk - something that is totally biodegradable, and some more, the GM material is a combination of silkworm and spider, both exist in nature.

    Anyhoo, congrats to the scientists who come up with this idea.

    1. Re:Why is there any concern about GM silk? by shione · · Score: 5, Funny

      1. Genetically modified spider escapes into the wild. It mates with other sipders creating a legion of these spiders with super silk. The super silk not only catches normal critters but large animals as well get tangled in the web unable to get out. Hope you all have a Phial from the elves.

      2. New spider silk isn't as sticky as normal spider silk. Spiders die of starvation. Pests grow to plague proportions

      3. Spider spins web in someones doorway. Homeowner is pissed at new wall.

      4. Profit! (GM spider escapes into the wild and mates with spiders in someones backyard. Patent troll finds GM spider and sues homeowner of ip theft and distribution!)

    2. Re:Why is there any concern about GM silk? by TheRaven64 · · Score: 4, Informative

      1. Genetically modified spider escapes into the wild

      They're genetically modifying silk worms, not spiders.

      It mates with other sipders creating a legion of these spiders with super silk.

      The silk is the same silk that spiders produce normally - that's the point.

      New spider silk isn't as sticky as normal spider silk

      Spiders produce two kinds of silk (massive oversimplification). The sticky stuff is relatively weak, the non-sticky stuff is used for structural parts of their webs. Go and poke a spiderweb sometime - you'll find some parts stick to you and tear easily, other parts don't stick and are tougher. Presumably the researchers are trying to make silk worms produce the non-sticky variety, as there is little call for silk that sticks to everything and tears very easily.

      --
      I am TheRaven on Soylent News
    3. Re:Why is there any concern about GM silk? by Anonymous Coward · · Score: 5, Informative

      7 types, sir!

      Also, there is much variation between types of spiders with Darwin's Bark spider having the strongest silk of all (drag-line silk from the major ampullate gland)!

      And the biggest research that needs to be done is in microfluidics because it's the pH, tension, and hydration status of silk dope that determine the properties of the fibers (those three affect the folding/alignment motifs that make up the super-structure. Spiders regulate this by the speed at which they pull the silk from their spinnarettes. A stupid silk worm will never be able to match this (they naturally make a triangular fiber, whereas a spider's is round). We're trying to put silk worm genes into corn and other crap, but bacterial cell factories produce the proteins efficiently already.

    4. Re:Why is there any concern about GM silk? by MightyYar · · Score: 3, Insightful

      Yeah, I'll get right on that.

      Did you people never have childhoods?

      --
      W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
    5. Re:Why is there any concern about GM silk? by silentbrad · · Score: 2

      Moths, actually. And apparently, they can't reproduce without human intervention.

  3. Did anyone else read the headline.. by neokushan · · Score: 2
    --
    +1 IDisagreeSoHeMustBeATrollOrAnAstroturferOrAShill
  4. Just keep Peter Parker out of that lab by Arancaytar · · Score: 5, Funny

    Then everything will be fine.

  5. Submitter did NOT RTFA by Magada · · Score: 4, Informative

    Actual quote from the actual fine article:

    their eventual aim is to produce silk from worms that has the toughness of spider silk.

    --
    Something bad is coming when people are suddenly anxious to tell the truth.
    1. Re:Submitter did NOT RTFA by JimWise · · Score: 2

      Commenter did NOT RTFFA (Read The Full Fine/F*cking Article):

      Smack dab in the middle of the article is the actual quote:

      GM worms produced by a team led by Professor Don Jarvis of Wyoming University seem to be producing a composite of worm and spider silk in large amounts - which the researchers say is just as tough as spider silk.

  6. More details around this spider silk by kodiaktau · · Score: 4, Informative

    Wonder if this is a part of an lead-in on the research.

    Looks like WYU is sitting on a ton of patents around spider silk technologies.

    Nicer pictures of this article can be found at http://inhabitat.com/genetically-modified-silkworms-spin-super-strong-spider-silk-for-bandages-and-bulletproof-vests/

  7. Goats? by Rytr23 · · Score: 2

    I thought they were putting those spider genes into goats years ago to have them spin the super silk instead of milk. I guess that went nowhere.. I would have liked to seen some goat-spider beast running around...

    --
    So many injustices..so little time..
    1. Re:Goats? by sirdude · · Score: 2

      That's the first thing that came to my mind as well. The goats were engineered to produce milk with high quantities of protein found in spider silk.

      P.S. It's a pity that the BBC has to stoop to sensationalising their headlines. "GM silk worms make Spider-Man web closer to reality"? Twits.

    2. Re:Goats? by sirdude · · Score: 2

      ...and I forgot to mention that the Goat story also came from UW. Presumably it's the same group involved.

  8. Please excuse me some SMAC by arcite · · Score: 2

    I have to upgrade my hovertank to silksteel armor, Yang won't know what hit him!!

  9. Re:now my underwear won't tear by Chrisq · · Score: 3, Funny

    when da bitches try to rip em off me.

    The problem is that loose thread was like a cheese wire and it ripped your dick off

  10. Is this biopiracy? by Chrisq · · Score: 4, Funny

    I hope the Chinese get the credit for the original silkworm genes

    1. Re:Is this biopiracy? by T.E.D. · · Score: 2

      Roughly the same credit Iraqis get for Wheat.

  11. In weight-for-weight terms by Anonymous Coward · · Score: 2, Funny

    Pound-for-pound, the amoeba is the most vicious animal on Earth.

  12. Re:GM silkworm by TheRaven64 · · Score: 5, Informative

    It's also interesting for things that are only partly silk. Pashmina wool comes from the underside of the chin of the nepalese goat and is amazingly soft, but very fragile. You can't make things from it if you want to be able to wear them more than once, so you mix in some silk to add strength[1], but the more silk you add the more of the softness and warmth you lose. Stronger silk would mean that you could weave fabrics with a very small amount of silk and a lot of something softer.

    [1] It amused me to see street sellers in NYC advertising pashmina shawls as '50% silk!' as if that was a good thing. The high quality ones are at most 20% silk. The silk is a lot cheaper than the wool.

    --
    I am TheRaven on Soylent News
  13. Management by Anonymous Coward · · Score: 4, Funny

    it is unfeasible to 'farm' spiders for the commercial production of their silk because the arachnids don't produce enough of it

    These spiders obviously need a harsh lesson about the economic climate we live in. They're never going to produce enough if you just get some other creatures to make it instead. Rank all the spiders by silk production, fire the ones at the bottom of the list. Things'll soon turn around.

    coupled with their proclivity for eating each other

    That's actually a good sign. A little healthy competitive pressure.

  14. I was bitten by one. by Maintenance+Goof · · Score: 2

    Now I have worm senses.

  15. Re:Don't genetically modified silkworms... by dkf · · Score: 2

    I know that in this area of CT the mulberry trees were destroyed by introduction of silkworms.

    You are aware that mulberry trees are the natural habitat of silkworms? They're specialists and don't live on anything else. Moreover, it sounds like before that there was relatively little predation upon those trees, allowing them to get much larger and more common than would normally happen. Because of that, what you had there was a classic case of what happens when a predator species is introduced into a prey-rich environment. It happens.

    --
    "Little does he know, but there is no 'I' in 'Idiot'!"
  16. Re:Don't genetically modified silkworms... by LWATCDR · · Score: 2

    "More to the point, can't better silk be synthetically produced on a large scale? Same question applies for other animal based textiles, such as wool, leather, fur, etc"
    No.
    and no.
    next question?
    Okay lets get a little real here.
    1. leather. leather has some qualities that are not found in any other material. It is required for motorcycle racers to wear because it offers the best protection. Nothing man made can replace it. Also most leather is a by product of animals being killed for meat. Exceptions are for some of the exotics which if you want to boycot be my guest as they are nothing but an ego trip. So as long as people eat meat using the leather from that does not contribute to any suffering.
    2. Wool. Sheep don't die to get wool folks. As far as I know sheep raised for wool are protected, feed, and cared for by humans. It is an actual advantage for the Sheep and is an almost symbiotic relationship. So what is wrong with wool?
    3. Fur. Well unless you live in the arctic I see no reason to wear it. So boycot that all you want.
    Silk! if we could make it we would. So no there is no better way. Besides they are just bugs. Sorry folks but if you kill flys, ants, and roaches then you really shouldn't have an issue with this.
    I do not like "factory farms" and other forms of animal cruelty but when you go too far in your objections it marginalizes the argument. AKA Wool.

    --
    See my blog http://ilovecookes.blogspot.com/ for light hearted technical information.
  17. No spider farms? Great. by Vyse+of+Arcadia · · Score: 3, Funny

    I am extremely ok with spider farming being infeasible. Accidentally wandering into a spider farm is the stuff of nightmares.

  18. Re:GM silkworm by MightyYar · · Score: 3, Funny

    It amused me to see street sellers in NYC advertising pashmina shawls as '50% silk!' as if that was a good thing.

    Amazing, since otherwise they seem like the kind of people you can trust.

    --
    W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
  19. Re:Don't genetically modified silkworms... by MightyYar · · Score: 2

    What? Gypsy Moth is Lymantria dispar. Silk worm is Bombyx mori. There are many types of mulberry, and while I'm sure the others have been introduced, there is a species of mulberry tree native to CT.

    --
    W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
  20. Nexia by Baby+Duck · · Score: 2

    I used to own stock in Nexia Biotechnologies, a Canadian company. The goats weren't the problem. Extracting the silk proteins from the milk weren't the problem. Spinning the proteins into silk strands were the problem!

    Many of the same proposed applications of the spider silk biosteel could also be fulfilled by nanotubes, but nanotubes would be even stronger. During the same time period that Nexia was improving its spinning process, several companies were making breakthroughs with nanotube manufacturing so that the price per inch would dramatically fall. Nexia saw the writing on the wall. Someone, somewhere, would make cheap nanotubes of appreciable lengths well before Nexia could make a competing offering.

    There's also the debacle of Nexia vs. the FDA. Nexia argued that since their silks were natural substances, they didn't need stringent safety testing for applications such as medical sutures. The FDA agreed so Nexia pushed ahead with their next stages of research. Down the road, the FDA changed their mind. Nexia didn't have the capital to afford all the testing trials the FDA was now demanding.

    Well before the Chinese company acquired Nexia, Nexia sold most of its intellectual property to an American company (in Virginia? Wyoming?). The bulk of that IP is proven counter-agents to certain chemical warfare attacks.

    Interestingly, Nexia was trying to splice spider silk DNA into plants. Grow them as a crop. Grind up their leaves. Sift out the proteins. But then you're still stuck with the underwhelming spinning process.

    --

    "Love heals scars love left." -- Henry Rollins