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Multiple Sclerosis Damage Washed Away By Stream of Young Blood

FatLittleMonkey writes "A new study on mice suggests damage caused by diseases like Multiple sclerosis, as well as natural aging, can be reversed by an infusion of stem cell rich blood from younger mice. Multiple sclerosis is a chronic inflammatory disease that erodes the fatty myelin sheaths around the axons of the brain and spinal cord, and can result in serious disability. Similar effects occur naturally with aging. From New Scientist: 'White blood cells called macrophages from the young mice gathered at the sites of myelin damage. Macrophages engulf and destroy pathogens and debris, including destroyed myelin. "We know this debris inhibits regeneration, so clearing it up is important," says team member Amy Wagers of Harvard University.' Here's the academic paper's abstract."

29 of 216 comments (clear)

  1. Virgins... by bhagwad · · Score: 5, Funny

    Need to bathe me in some virgin blood - Ahahahahaha!

    1. Re:Virgins... by fuzzyfuzzyfungus · · Score: 4, Funny

      Countess Bathory, MD, PhD, postumously awarded the Nobel Prize in Medicine?

    2. Re:Virgins... by Samantha+Wright · · Score: 4, Interesting

      You know a joke is obvious when you get to the comments section only to discover three people have already made it. Alas!

      Unrelatedly, TED has a lot to say on the topic of ageing, much of it accessible. The general gist seems to be "as long as food is plentiful, it's in our best interest to reproduce fast and die young, so eating conservatively makes our bodies think they need to survive longer."

      --
      Bio questions? Ask me to start a Q&A journal. Computer analogies available for most topics!
    3. Re:Virgins... by voidphoenix · · Score: 4, Funny

      They did say "young"... I don't think 40-year old virgins count... ;p

  2. Finally! by BradleyUffner · · Score: 5, Funny

    A use for all those annoying neighborhood children.

    1. Re:Finally! by Darinbob · · Score: 5, Funny

      Hey you kids! Don't get off my lawn! In fact, there's even better grass down in the basement, come check it out!

    2. Re:Finally! by comrade+k · · Score: 3, Funny

      Well, you can be sure they're free of HIV -- No sex to transmit it to them!

      --
      "Every vision is a joke until the first man accomplishes it; once realized, it becomes commonplace." -Robert H. Goddard
  3. Re:Links to Aspartame by hedwards · · Score: 5, Insightful

    There aren't any credible reasons to believe that aspartame causes MS. If that were the case you wouldn't expect the highest rate of MS in the world to be in Seattle where folks tend to be fairly paranoid about aspartame and artificial sweeteners in general.

  4. Re:Back to the Future by SomePgmr · · Score: 5, Funny

    We should try it anyway. For Marty's sake.

  5. Good news, everyone! by roman_mir · · Score: 4, Funny

    Professor Farnsworth knew it all along, so did Mr. Burns.

  6. Re:Links to Aspartame by CRCulver · · Score: 4, Informative

    Absolutely not - but it would exacerbate the problem of overpopulation, at least until we learn to terraform other planets and/or live in space.

    One of the points made in Kim Stanley Robinson's trilogy beginning with Red Mars is that even with things like multiple space elevators, you'd never be able to move more people off the planet than are being born everywhere on it. The colonization of space is not a solution for population pressures.

  7. Re:Links to Aspartame by Sarten-X · · Score: 5, Informative

    I'm afraid not. There is no conclusive link between aspartame and MS within the scientific community. Such claims are often repeated by doctors-turned-authors, scam artists, and conspiracy theorists, though.

    Moving on, I do wish this madness with stem cells would end. They have their own soul as much as my feces (mostly dead blood cells and bacteria) do.

    --
    You do not have a moral or legal right to do absolutely anything you want.
  8. Re:Links to Aspartame by antifoidulus · · Score: 5, Funny

    I always thought the high incidence of MS in Seattle was due to their headquarters being in Redmond

    *ducks

  9. Re:Links to Aspartame by Anonymous Coward · · Score: 4, Interesting

    I've been diagnosed with Multiple Sclerosis. Started with lesions in my spine taking out all the sensation from my neck to my hips for a month or so, then the blindness in one eye, since then various bouts of stocking+gloves neuropathy that come and go, mixed with random sensations of walking barefoot on gravel and every now and then I lean right while walking in a straight line.

    At the time of the first incident, I was drinking about 2 liters (straight from the bottle) of non-diet Dr. Pepper a day, and didn't touch the diet stuff.

    Now I drink the diet stuff (still about 2L/day) and lost 60 pounds. Doesn't seem to make a difference neurologically to me. YMMV.

  10. Re:Links to Aspartame by Ethanol-fueled · · Score: 4, Funny

    MS and MSFT are both equally virulent diseases which have resisted our efforts to cure.

  11. New Market for Children? by TW+Burger · · Score: 3, Interesting

    I could see this becoming a new business in the third world. Selling children's blood would not be far fetched. Look up were all (or most) of the hair for natural wigs and extensions comes from: Little girls in India.

  12. Re:Links to Aspartame by narcc · · Score: 4, Insightful

    Ugh, this aspartame nonsense is the worst kind of pseudo science. I suppose you also believe that vaccines cause autism? What about peach-pits curing cancer?

    Wait, let me guess: the "medical establishment" doesn't want you to know the "shocking truth".

    Looking below, it looks like you also believe Monsanto is in on the conspiracy!

    I'd laugh if spreading nonsense like you've been doing wasn't so dangerous. People like you are causing real and measurable harm.

    Leave medical science to the experts. Hmmm... I better clarify that: Reading a few conspiracy websites does NOT make you an expert!

  13. That explains a lot by HangingChad · · Score: 4, Funny

    natural aging, can be reversed by an infusion of stem cell rich blood from younger mice.

    That explains how Dick Cheney manages to hang on so long; he's been sucking the life force from local villagers at night.

    --
    That's our life, the big wheel of shit. - The Fat Man, Blue Tango Salvage
    1. Re:That explains a lot by 93+Escort+Wagon · · Score: 5, Insightful

      You know, people make jokes, but that dude had his first heart attack (of 5) 34 years ago. Whatever he's done to keep himself alive seems to have worked pretty damn well.

      What he's done is to just be rich - it works wonders with regards to access to health care.

      --
      #DeleteChrome
  14. Re:Back to the Future by jamesh · · Score: 5, Funny

    I hate to break it to you, but he has Parkinson's, not MS.

    when all you have is a hammer, everything looks like a skull.

  15. Not as sexy, but MS found to be reversed by diet by Anonymous Coward · · Score: 4, Interesting

    Even cheaper, and something that can't be patented by unscrupulous scientists and pharmaceutical companies, but researchers have already found MS can be reversed by changing your diet.

    http://www.youtube.com/watch?v=KLjgBLwH3Wc

    Dr. Terry Wahl presented at TEDxIowaCity that eating nutrient dense foods reversed her second stage MS, and they have moved on to trying it is more subjects. But it sure won't get government stem cell money. And the recommendations fly in the face of government dietary recommendations. Not to mention probably more than a few slashdotters habits.

    Compare, trials in mice. Versus clinical trials in humans.

  16. Sounds great, except for ethical considerations by kheldan · · Score: 3, Interesting

    Easy enough, right? Just get regular transfusions from someone young. Except nobody is going to advocate blood donations from children. Could you have your own cells harvested, reverted to stem cells, and reintroduced into your bloodstream?

    --
    Are YOU using the TOOL, or is the TOOL using YOU? Think about it!
  17. Re:Links to Aspartame by FatLittleMonkey · · Score: 3, Informative

    I only submitted the story because of the original headline "MS damage washed away by a stream of young blood", in anticipation of Microsoft jokes. (Curse you, competent editors.) Glad to see I got my jokes after all.

    Thank you sir and/or madam.

    --
    Science is all about firing a drunk pig out of a cannon just to see what happens.
  18. Some issues by currently_awake · · Score: 5, Insightful

    The cells of the human body have a limited lifespan. The aging process is basically you running out of replacement cells. Using blood transfusions will help some, but it's the stem cells that will make you young. And stem cells from someone else will trigger your immune system- and using anti-rejection drugs is a horrible way to live. So you want your own rejuvenated stem cells, and getting there should only be one Apollo project equivalent away- so about 10 years if you have the money. The second issue- it will cost. So most medical plans won't cover this. Meaning the rich get to live forever, not you. And if you don't see a problem with that, just think of Bill Gates NOT getting old and retiring. Ever. Having a ruling class of immortals running the earth is how that will end. Rich enough they don't care about you, from another generation so they don't understand you, owning everything and constantly looking for the next google so they can buy it up. This would make a cool plot for a science fiction movie, but in real life it will suck.

    1. Re:Some issues by pwizard2 · · Score: 4, Insightful

      Having a steady supply of stem cells is only part of the solution, it's a matter of efficiency. Will the stem cells be able to repair organs and tissues faster than they are becoming damaged? If not, the subject will die when something critical fails. Also, DNA only becomes more and more degraded over time. This will ultimately cause some sort of terminal cancer in the subject. Until there's a 100% effective cure for cancer, this would never work.

      Also, this sort of immortality would be more of a curse than a blessing even if it were possible to pull it off. Who would want to live in a broken-down, aged body forever, kept alive only by a steady stream of stem cells? Is this world such a nice place that you would want to stay here forever, even if it means existing like that? I wouldn't do it even if I had the option. Death would be preferable. The stem cells wouldn't give someone who is 250 years old the same body they had at 18...they would probably be trapped in a bed in a severely debilitated state. The worst type of immortality is one that brings no pleasure.

      --
      "It is a denial of justice not to stretch out a helping hand to the fallen; that is the common right of humanity."
    2. Re:Some issues by walshy007 · · Score: 5, Insightful

      Who would want to live in a broken-down, aged body forever, kept alive only by a steady stream of stem cells?

      So long as my mind is intact, fully functional and I have a decent means to communicate with the outside world? I would.

    3. Re:Some issues by pwizard2 · · Score: 3, Insightful

      So long as my mind is intact, fully functional and I have a decent means to communicate with the outside world? I would.

      Are you sure? It's easy to feel that way now, but visualize yourself in that situation. Even if you were able to communicate and had your mental state preserved, there is no guarantee that you would be able to enjoy life or do much of anything. What would someone in that state do to pass the time? After several years of being trapped in a useless husk of a body and spending your days staring at the ceiling, would you still want to live? The real horror would be that you would have centuries of that to look forward to and that all your days will be mostly the same. Would people still come to see you after your friends and family passed on, assuming they didn't get the treatment?

      I'd rather live a normal lifespan and then die surrounded by friends and loved ones. Having my consciousness cease to exist would be a better alternative to that sort of immortality. I'm 28, in good health, and I'm already weary of this world. I stay here because I have people who care about me and there are things I want to do in life, but when my time comes I will go without complaint or regret. Seneca taught that being able to face and accept inevitable death without fear is a sign of strength and wisdom. Quality, not quantity of life is what matters.

      --
      "It is a denial of justice not to stretch out a helping hand to the fallen; that is the common right of humanity."
    4. Re:Some issues by theshowmecanuck · · Score: 4, Insightful

      there is no guarantee that you would be able to enjoy life or do much of anything

      So how did Steven Hawking take your recommendation that he should just die.

      --
      -- I ignore anonymous replies to my comments and postings.
  19. Re:Monsanto? by Martin+Blank · · Score: 4, Informative

    It's due to a hoax that made the email rounds years ago and it's never been completely eradicated. People keep it going because of irrational fears and conspiracy theories.

    --
    You can never go home again... but I guess you can shop there.