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Drug Turns Immune System Against All Tumor Types

Posted by Unknown on from the confused-mice-with-foot-tumors dept.

sciencehabit writes, quoting an article in Science: "A single drug can shrink or cure human breast, ovary, colon, bladder, brain, liver, and prostate tumors that have been transplanted into mice, researchers have found. The treatment, an antibody that blocks a 'do not eat' signal normally displayed on tumor cells, coaxes the immune system to destroy the cancer cells." The abstract and full paper are freely available. It seems fairly promising: "In mice given human bladder cancer tumors, for example, 10 of 10 untreated mice had cancer that spread to their lymph nodes. Only one of 10 mice treated with anti-CD47 had a lymph node with signs of cancer. Moreover, the implanted tumor often got smaller after treatment — colon cancers transplanted into the mice shrank to less than one-third of their original size, on average. And in five mice with breast cancer tumors, anti-CD47 eliminated all signs of the cancer cells, and the animals remained cancer-free 4 months after the treatment stopped."

15 of 330 comments (clear)

  1. It worked even better by phantomfive · · Score: 5, Funny

    It worked even better in mice that didn't get cancer transplants!

    I kid, I kid.

    --
    "First they came for the slanderers and i said nothing."
    1. Re:It worked even better by __aayejd672 · · Score: 4, Funny

      I just want to see the mice with breasts

    2. Re:It worked even better by Phrogman · · Score: 3, Funny

      Your on the internet - there's probably a whole series of websites devoted to that very subject. Check 4Chan or Reddit :P

      --
      "The first time I got drunk, I got married. The second time I bought a chimpanzee, after that I stayed sober" Arian Seid
  2. /b/ by Alex+Belits · · Score: 3, Funny

    I propose to perform the next experiment on /b/.

    Then maybe we will be able to continue this thread there.

    --
    Contrary to the popular belief, there indeed is no God.
  3. Re:Mouse != Human by reboot246 · · Score: 5, Funny

    Then let's test it on lawyers! They're almost human,

  4. Re:Mouse != Human by Anonymous Coward · · Score: 5, Funny

    Yes, but what if it doesn't kill them?

  5. Re:But... by Anonymous Coward · · Score: 5, Funny

    Your post was possibly the post important message an AC has ever shared with this website. Thanks.

    Indeed. If it has just finished "P.S. first post", it would have been perfect.

  6. Re:Mouse != Human by Anonymous Coward · · Score: 5, Funny

    Then it's not a cure for cancer.

  7. Re:But... by priceslasher · · Score: 5, Funny

    Already happened, it was called "I am Legend" (the movie). Will Smith saved us but I think the zombies got him in the end.

  8. Re:Mouse != Human by CubicleView · · Score: 5, Funny

    I have a theory that with enough research we’ll eventually be able cure any disease that mice are afflicted with.

  9. Re:But... by brdsutte · · Score: 3, Funny

    Auto-immune? I bet House can handle it ...

  10. Re:Mouse != Human by slashmojo · · Score: 4, Funny

    They're almost human

    Dear Slashdotter,

    This behaviour is a flagrant violation of our most sacred code of conduct and must be stamped out.

    Please inform us of any lawyer found to be almost human so that we may take corrective action forthwith.

    Your cooperation in this matter is appreciated.

    Regards,

    The Bar Council

  11. Re:But... by fuzzyfuzzyfungus · · Score: 3, Funny

    Will he have to? It's never lupus.

  12. Re:But... by necro81 · · Score: 3, Funny

    I was conscious but felt completely numb - I wasn't really aware of what was going on. But I have recovered completely from that.

    Did you see a distant ship's smoke on the horizon?

  13. Re:But... by Larryish · · Score: 3, Funny

    Why does trepanning always get a bad rap?

    I mean, we always made sure to follow it with leeches.