Anti-Ebola Drug ZMapp Makes Clean Sweep: 18 of 18 Monkeys Survive Infection
Scientific American reports, based on a study published today in Nature, that ZMapp, the drug that has been used to treat seven patients during the current Ebola epidemic in West Africa, can completely protect monkeys against the virus, research has found. ... The drug — a cocktail of three purified immune proteins, or monoclonal antibodies, that target the Ebola virus — has been given to seven people: two US and three African health-care workers, a British nurse and a Spanish priest. The priest and a Liberian health-care worker who got the drug have since died. There is no way to tell whether ZMapp has been effective in the patients who survived, because they received the drug at different times during the course of their disease and received various levels of medical care.
NPR also has an interview with study lead Gary Kobinger, who says that (very cautious) human trials are in the works, and emphasizes the difficulites of producing the drug in quantity.
Project 18 monkeys is a go.
I for one welcome our simian overlords.
"Kill 'em all and let Root sort 'em out"
When the human testing starts, should it be old people first? afftected-continent people first? family-receives-high-payment people first?
I think they should be volunteers at the very least.
with Ebola control is health care infra-structure in affected countries. A far cry from what would be necessary to contain further spread. There was one report on a radio station that there are like 10 doctors in a whole country (Africa, forgot the name).
Even if you have the best drug available defeating the virus in a day, it won't help at all under those circumstances - spread by body fluids from infected individuals.
The outcome can only be guessed...
you forgot to read the summary or the article
Anti-Ebola Drug ZMapp Makes Clean Sweep: 18 of 18 Monkeys Survive Infection
brandelf -t FreeBSD
Finally the monkeys are safe. Praise be.
Good news for the ones that can afford the treatment, either personally or through their government. Death for the others.
and is the usa the last resort jail / prison healthcare system will cover it as well.
Looks like The Onion got this one wrong.
Experts: Ebola Vaccine At Least 50 White People Away
I suppose it's a commentary on the state of the world that The Onion is so often inadvertently right with their headlines.
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Considering the growing fraction of US population that live in prisons, that seems fair.
Who/Where can we donate to help get basic supplies to the doctors in Africa; without 98% of it disappearing into 'overhead'?
That 50% better than 12 out of Twelve Monkeys!
Look, I'm all for getting as much Zmapp to patients as is possible. I think a lot of people are agreement on this.
But we also need to do something about the effed up process of the approval of drugs and vaccines for these deadly diseases.
I'm thinking specifically about the malaria vaccine that has been known to be effective since '96/'97, but which has been held up for extended testing trials by (IIRC) the British drug regulators, who again put a hold on it this spring because it might not be entirely effective in newborn infants.
Meanwhile two million children are dying every year from malaria. This is a really, really, really, screwed up situation, and we have an ethical obligation to do what we can to put an end to these processes.
Even if the latest delay is "only" three months, that's a half million kids or so. It's unconscionable how poor the risk management analysis is - the perfect can be the very, very deadly enemy of the good. And so can drug-agency bureaucrats.
My God, it's Full of Source!
OUTSIDE_IP=$(dig +short my.ip @outsideip.net)
That depends on whether the monstrous fuck-up is just extinction of one plant variety or Triffidized tobacco.
Who is John Cabal?
I don't care if your bleeding from the eyeballs, leave my cigarettes alone!
And did you exchange a walk on part in the war for a lead role in a cage? - Pink Floyd.
We're not told the size of the control group, but if it were 18 monkeys to match the treated group, you had a very hardy set of monkeys or a less aggressive strain of the virus.