Slashdot Mirror


Companies Genetically Engineer Spider Silk

gthuang88 writes: Spider silk is touted for its strength and potential to be used in body armor, sports gear, and even artificial tendons and implants. Now several companies including EntoGenetics, Kraig Labs, and Araknitek have developed genetic approaches to producing commercial quantities of the stuff. One method is to implant spider genes into silkworms, which then act as spider-silk factories. Another is to place the gene that encodes spider web production into the DNA of goats; these "spidergoats" then produce milk containing spider-silk proteins that can be extracted. There's still a long way to go, however, and big companies like DuPont and BASF have tried and failed to commercialize similar materials.

82 comments

  1. Spider Goats by Anonymous Coward · · Score: 2, Insightful

    What could possibly go wrong. Better hope they don't mutate or start biting people.

    1. Re:Spider Goats by fustakrakich · · Score: 5, Funny

      Cool, Giant eight legged spider goats, head butting little kids into the ravine.

      --
      “He’s not deformed, he’s just drunk!”
    2. Re:Spider Goats by alexander_686 · · Score: 2

      If you were bitten by one, would you have the proportional strength of a spider or of a goat?

    3. Re:Spider Goats by penguinoid · · Score: 4, Funny

      I bet if one of these bite you, you'll end up with the fussy diet of a goat, and the brains of a spider.

      Basically, indistinguishable from your average American.

      --
      Don't waste your vote! Vote for whoever you want, unless you live in a swing state it won't matter anyways
    4. Re:Spider Goats by Austerity+Empowers · · Score: 1

      There goes my massive MMO spider silk horde. Leave it to science to devalue my investments.

    5. Re:Spider Goats by Anonymous Coward · · Score: 0

      Nothing, considering that the story is completely wrong. They are not injecting spider DNA into goats. They have instead found that goats have the same gene to produce a specific protein, which is also found in spider silk. A completely separate gene, which is also already in the goats, is what enables or disables it. They simply want to turn the gene on so that the goats will begin producing the protein they are already capable of.

    6. Re:Spider Goats by HairyNevus · · Score: 1

      I'd much rather have spider DNA inserted into goats than have people farming black widow spiders en masse for their webs.

      --
      You were critically hit for no damage. The bruise will look nice, and maybe the scars will make good party talk.
    7. Re:Spider Goats by Anonymous Coward · · Score: 0

      They're test facility for spider goats is less than 10 miles from me. I do think about it sometimes, but I realize there are much more terrible things in this world.

    8. Re:Spider Goats by bill_mcgonigle · · Score: 1

      Cool, Giant eight legged spider goats, head butting little kids into the ravine.

      I don't care what they say, you're OK (no points today).

      --
      My God, it's Full of Source!
      OUTSIDE_IP=$(dig +short my.ip @outsideip.net)
    9. Re:Spider Goats by Bengie · · Score: 1

      Does the Goat Simulator support this mode of play?

    10. Re:Spider Goats by Anonymous Coward · · Score: 0

      Really funny. :>

    11. Re:Spider Goats by Anonymous Coward · · Score: 0

      Cool, Giant eight legged spider goats, head butting little kids into the ravine.

      Rumor has it that the South Park facility is splicing genes to create giant eight-legged spider goats with four asses.

    12. Re:Spider Goats by Anonymous Coward · · Score: 0

      I bet if one of these bite you, you'll end up with the fussy diet of a goat, and the brains of a spider.

      Basically, indistinguishable from your average American.

      Nah - spiders are much smarter - the average American possesses the brains (and attention span) of a fruit fly.

    13. Re:Spider Goats by jamiesan · · Score: 1

      I heard they were going to nerf spider silk drops in East Karana.

    14. Re:Spider Goats by Anonymous Coward · · Score: 0

      Spider Goats? That just sounds baaaa-dd!

      Don't worry, folks. I'll be here all week. Don't forget to tip your server.

  2. Implant it into humans by durrr · · Score: 2, Funny

    Then wait until the boys hit puberty.
    Of course it would lose all value due to the overabundance so the investment will never pay off.

  3. Spidergoat ... does what a spidergoat does! by Anonymous Coward · · Score: 0

    Homer Simpson thought was a pig see "Spider Pig" episode of The Simpsons.

      It seams to be a long shot to take a Goat and it's milk as a route to silk. Why not amp up the silk moths or will the quantity of these proteins per gallon of milk out produce the silk per cocoon?

  4. Waiting for the infringement lawsuit... by DougOtto · · Score: 4, Informative

    Spider-Pig, Spider-Pig, Does whatever a Spider-Pig does. Can he swing from a web? No, he can't, he's a pig, Look out, he is a Spider-Pig!

    --
    Solving Unix problems since 1989...
  5. Everlasting lingerie products? by Anonymous Coward · · Score: 0

    Great! Please make pantihose, tights, stockings, holdups, ....!

    1. Re:Everlasting lingerie products? by Shortguy881 · · Score: 1

      Don't hold your breath. Spider Goat was created 4 years ago. Really this whole article is out of date. Angela Shah must've been sleeping the last decade.

      Whats worse and not even mentioned in the article is that only a handful of spiders produce silk stronger than steel. The ones whose genes were spliced into the goat and silk worm produce a weaker silk. Maybe it was the easiest set of genes to isolate but it was useless as the silk only had a fraction of the strength of steel.

      --
      Brilliance without wisdom, power without conscience. Ours is a world of nuclear giants and ethical infants.
  6. All hail spidergoat by kwiecmmm · · Score: 1

    I wish to offer my services to our new spidergoat overlords.

    1. Re:All hail spidergoat by ericbrow · · Score: 1

      Spidergoat, Spidergoat, does what ever a Spidergoat does...

  7. Spider silk in space by Spy+Handler · · Score: 1

    Suspend spider silk from a satellite.
    Employ an army of spiders to ferry micro-cargo from earth to space.

  8. Mother Nature still rockin it! by pr0t0 · · Score: 1

    As a species, we've advanced pretty well and can use technology to reproduce all kinds of natural processes. It's easy to be lulled into thinking we can do just about anything. So it's kind of nice to see we still have some tricks to learn. I mean, no one is surprised we can't yet dial-in desired genetic traits a la Gattaca, but engineering spider silk seems fairly simple by comparison. I suppose once we have total control over the individual placement of atoms, at scale, anything really will be possible.

    --
    I'm sorry, but your opinion seems to be wrong.
    1. Re:Mother Nature still rockin it! by Wycliffe · · Score: 1

      I suppose once we have total control over the individual placement of atoms, at scale, anything really will be possible.

      Yes, possible, but mother nature is also better at discovering advantageous arrangements thru trial and error. We still can't
      predict simple protein folds. Many of the substances we take for granted were discovered first naturally being produced
      by plants and animals. There are hundreds of substances and techniques where the plant and animal kingdom still is
      far and away better than anything we can replicate in the laboratory. Even many medicines are produced in a host whether
      that's a pig or an egg.

  9. To GMO or not to GMO? by mi · · Score: 2

    One method is to implant spider genes into silkworms, which then act as spider-silk factories.

    There are people out there, who are sincerely concerned about whether vitamin-C they are offered was "genetically modified"... How are you going to sell such GMO silk to them?

    --
    In Soviet Washington the swamp drains you.
    1. Re:To GMO or not to GMO? by MightyYar · · Score: 2

      You don't. This is how the Amish started. People who don't embrace new technology will, on balance, become marginal. If they aren't marginal, then the whole society will become marginal as technology-using societies surpass it.

      --
      W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
    2. Re:To GMO or not to GMO? by Anonymous Coward · · Score: 0

      I would believe for one that they would sell it to the other 7 billion morons on this rock...

      P.s: do note that the organic consumers are ALSO morons. We all are...

    3. Re:To GMO or not to GMO? by ChrisMaple · · Score: 1

      GMO is not even a hypothetical problem if you're not eating it.

      The Amish are thriving. Protected by the military and technological strengths and by the freedoms of the United States, their industriousness, relative lack of modern perversions, and high birth rate expands their population and wealth. There are lessons to be learned here, and the country could benefit greatly by learning them.

      --
      Contribute to civilization: ari.aynrand.org/donate
    4. Re:To GMO or not to GMO? by MightyYar · · Score: 3, Insightful

      The Amish are thriving.

      They exist completely at the whim of their benevolent neighbors. They are here precisely because the Swiss were coming down on them rather hard. If we all became Amish, "we" wouldn't be around for very long.

      --
      W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
    5. Re:To GMO or not to GMO? by Anonymous Coward · · Score: 0

      Someone gave me one of those organic Kind Bars the other day that listed 'non-GMO glucose' as an ingredient. "Thank God!" I thought. I hate it when my C6H12O6 has it's genome altered! And to think, they say the opposition to genetic engineering is just ignorance and marketing.

    6. Re:To GMO or not to GMO? by stoploss · · Score: 1

      Someone gave me one of those organic Kind Bars the other day that listed 'non-GMO glucose' as an ingredient. "Thank God!" I thought. I hate it when my C6H12O6 has it's genome altered! And to think, they say the opposition to genetic engineering is just ignorance and marketing.

      Yes, and the polio vaccine that had SV40 contamination was pure to the limits of detection at the time (i.e. they had no idea it included SV40 or that SV40 was a threat).

      If the vaccine batches had been labeled "non-green monkey serum" as appropriate then that would have correlated with a lack of the adverse outcomes caused by SV40 contamination that the people who were exposed to the other vaccine lots were exposed to.

      Your attempt at satire is puerile. In fact, in case you couldn't follow the logic I will restate the point in small words.

      1. Nothing is completely pure.
      2. Some contaminants do bad things to people, even at levels we can't measure today.
      3. Sometimes it takes decades before these problems are found by scientists. By then the damage is done.

      But eat the kind bar, or not. I don't care.

    7. Re:To GMO or not to GMO? by mi · · Score: 1

      2. Some contaminants do bad things to people, even at levels we can't measure today.

      That's certainly true — whether the contaminants are genetically modified, or not...

      --
      In Soviet Washington the swamp drains you.
    8. Re:To GMO or not to GMO? by stoploss · · Score: 1

      Absolutely true. The Agent Orange used in Vietnam was approximately 99.5% pure herbicide. Of course, that remaining 0.5% was TCDD...

      For example, I'm convinced that in the future people will be revolted thinking about the pharmaceuticals and metabolites we currently dump out untreated from our wastewater treatment plants (and thus the people downstream from us consume).

    9. Re:To GMO or not to GMO? by Anonymous Coward · · Score: 0

      If you can find any reliable study showing ANY detectable difference between "GMO glucose" and "non-GMO glucose"... I'll give you a dollar.

    10. Re:To GMO or not to GMO? by Anonymous Coward · · Score: 0

      You don't. This is how the Amish started. People who don't embrace new technology will, on balance, become marginal. If they aren't marginal, then the whole society will become marginal as technology-using societies surpass it.

      On the other hand, people who rely too much on technology to do everything for them become mentally marginal - which makes them ripe for enslavement during the rise of the machines.

    11. Re:To GMO or not to GMO? by mi · · Score: 1

      Neither the herbicide, nor the TCDD, nor the pharmaceuticals and metabolites you mention have anything to do with genetic modifications — however despicable they may (or may not) be otherwise.

      Off-topic much?

      --
      In Soviet Washington the swamp drains you.
    12. Re:To GMO or not to GMO? by stoploss · · Score: 1

      Here you go: some people are applying the precautionary principle due to concerns about potentially as-yet undefined health concerns from consuming GMO foods. "Non-GMO glucose", while an imprecise term, putatively means the glucose was sourced/refined from non-GMO stock materials and thus would be unlikely to have any of the possible contamination they wish to avoid.

      Do try to keep up.

    13. Re:To GMO or not to GMO? by Anonymous Coward · · Score: 0

      Not sure, "we" would survive longer than any other first world country when the electricity fails and we're back to the horse and plow,
      "everyone" else is surviving without that knowledge.

      In a calamity where we're back to the stone age, you can bet good money if you know how to work a farm without electricity (and yes, some Amish cheat here and there) you'll outlive everyone else.

    14. Re:To GMO or not to GMO? by MightyYar · · Score: 1

      In a calamity where resources become scarce, I'd bet on the non-pacifists. The Amish would be completely screwed without their food stocks, farmland, and livestock.

      No matter how you look at it, they are completely dependent on the good will of the society around them.

      --
      W..w..W - Willy Waterloo washes Warren Wiggins who is washing Waldo Woo.
  10. wait, what? by wierd_w · · Score: 4, Informative

    I thought the magic in spider silk was 2-part.

    First, is the molecule-- but the second is how it gets "zipped" into a silk filament by the spider's spinnarets.

    http://www.nature.com/nature/j...

    Just putting the genes into a silkworm WILL NOT PRODUCE SILK LIKE A SPIDERS!

    Producing the proteins in goats wont fix the mechanical processing that spiders do.

    This is why these things keeps failing. The protein is only part of the package. They need nano-structure spinnaret simulants to spin the solution with as well.

    1. Re:wait, what? by Rinikusu · · Score: 1

      Well, reading the article, it appears they know this and have devised ways to do this. Those methods may or may not be cost-effective, which seems to be the gist of the article: Several labs are touting break-throughs in processing spider silk proteins produced by goats, e. coli, etc etc.

      --
      If you were me, you'd be good lookin'. - six string samurai
    2. Re:wait, what? by Anonymous Coward · · Score: 0

      So you're actually telling me that they need a web-shooter? https://en.wikipedia.org/wiki/...

    3. Re:wait, what? by Baby+Duck · · Score: 4, Interesting

      I actually invested money into the now dissolved Canadian company, Nexia Biotechnologies, which was the first to do the spider-goats. You are entirely correctly. Spinning the silk is the harder second part. The gains in reducing cost per meter couldn't keep the pace with similar gains in carbon nanotubes, which competed for many of the same practical applications. Nexia's first path to market was to be superstrong medical sutures. At first, the FDA promised expensive human trials would not be needed since the proteins were naturally occurring. When the FDA later about-faced, it was Game Over for Nexia, who sold the IP rights to a company in Virginia. They also sold the IP behind their proven anti-chemical warfare agents. But the tyrants of the world never used chemical warfare against the US military, so that was (thankfully) also a financial bust.

      Nexia was also trying to GMO a plant crop that could grow the silk protein in their leaves. After harvesting, the leaves would be grinded and sifted. However, you're still back to the same Spinning Problem that you highlighted.

      --

      "Love heals scars love left." -- Henry Rollins

    4. Re:wait, what? by wierd_w · · Score: 5, Interesting

      Just read the article myself;

      This is still about the protein itself, not the mechanical processing done by the spider to create the unique fibers they produce.

      Basically, the spider's silk protein is a bit like a "hook and latch", much like a zipper's teeth. Mass producing the protein produces "Zipper teeth", but that does not result in the unique conformation of a zipped up zipper.

      For that, you need the zipper pull.

      That's what a spider's spinnarets do. As the liquid crystal solution of spider protein gets pulled into the spinnaret, it gets compressed mechanically in a special fashion, which causes spontaneous self-assembly of these "zipper teeth", into a fully assembled, fully interlocking "zipper" of interlocked protein molecules. It is this fully interlocked assemblage that gives spider silk its unique mechanical properties.

      The shape and length of these structures in the spider's abdomen are crucial to correct assembly.

      As the linked Nature paper I linked to points out, this process is NOT incorporated in any currently used textile processing system.

      Getting bulk, high quality protein is only PART of getting mass produced spider silk. The other part is the mechanical processing.

      Silkworms do not have the structures that spiders do for processing their silk. Instead, silkworms produce a kind of salivary secretion through a much larger orifice. This orifice is much larger than a spider's spinnaret, and is not the same shape. This is why silk worms producing spider proteins will not produce silk of the same quality.

      Now, we have some pretty kick ass micro-pipette technology these days (and surface morphology control on silicon substrates from PV solar research) that could probably be used to create synthetic spinnarettes--- Just wet one side with the silk solution, then draw silk fibers from the other side.

      I just have never heard of any serious research into creating such synthetic spinnaret technologies.

    5. Re:wait, what? by wierd_w · · Score: 1

      One solution might be to re-purpose other tech from the bio-tech industry.

      Specifically, hollow silicon nanoneedle arrays.
      http://www.ncbi.nlm.nih.gov/pu...

      Grown with the correct length, diameter, and taper, they would function as mechanical analogues to spider spinnarettes. Wet one side, then "brush" the other to get the thread started-- then just gently tug on the resulting fibers.

      They would be very fragile things though. Would take very specialized equipment to handle, install, and prime them for service. They would also be far more fragile then ones made from insect chitin, so the drawing speed and pitch angle of the pull would have to be very carefully controlled to avoid breaking off the needles.

      Maybe pores in a sheet would work better?

    6. Re:wait, what? by Alomex · · Score: 1

      Nexia Biotechnologies, which was the first to do the spider-goats.

      A bit of trivia:

      A friend who was in-the-know claimed George W. Bush wore a spider-goat bullet proof vest during at least part of his presidency. FWIW he worked within the security establishment in Washington DC, but I have no way to verify his claim.

    7. Re:wait, what? by Immerman · · Score: 1

      Pores probably wouldn't do it either - spider spinnerets are fairly sophisticated protein-manipulation organs, they don't just squirt the protein through a sufficiently small nozzle.

      --
      --- Most topics have many sides worth arguing, allow me to take one opposite you.
    8. Re:wait, what? by wierd_w · · Score: 1

      Short of growing spinnarets on a tissue sheet from cultured spider cells, (which would give the exact organs needed), there is no way to fully replicate the features of a spider's spinnaret at this time.

      According to , the processes that transform the spinning dope from an disordered liquid crystal solution to insoluble fibers involves mechanical compression coupled with saline ion removal, and that the rate of draw from the spinning duct has a profound correlation with the tensility of the resulting fibers.

      This suggests that a "tapered silicon nanoneedle array" that has been doped to wick away saline ions from the needle's interior through the walls of the shaft, coupled with a controlled rate of draw, and a carefully selected for mechanical pore size, tube length, and taper, could result in a passable approximation of spider silk.

      It does not need to absolutely perfect; it just needs to approximate the features of spider silk. Perfect replication is likely not possible with current nano-technology.

    9. Re:wait, what? by Anonymous Coward · · Score: 0

      The problem with soft vests is they are fine against the blunter bullets (e.g. pistols) but cannot stop pointy bullets (rifle and assault carbine ammo with copper surface). A soft vest that will stop any .357 across the room, is easily penetrated by soviet 7.62x25mm Tokarev pistol of WW2 vintage, because of the long, slender bullet that has a lot of weight coupled to small diameter. To stop these treats, at least a thin metallic or ceramic plate is needed, to start breaking up the bullet. That's why Dragon Skin's ceramic mini-discus based technology received such a hype, as it promised the flexibility of soft vests, combined with the rifle-proofness of hardplate vests. Several US generals wore it in Iraq, but the weight issue was as bad or even poorer than Point Blank Interceptor sheet-plate vests.

    10. Re:wait, what? by Anonymous Coward · · Score: 0

      And I thought the silk worms weren't fun to raise either.

    11. Re:wait, what? by Anonymous Coward · · Score: 0

      Spiders are PRO at not getting their junk caught!!!

  11. I hope they remove the Sticky! by NotQuiteReal · · Score: 2

    Spider-Silk garments - how tacky!

    --
    This issue is a bit more complicated than you think.
    1. Re:I hope they remove the Sticky! by Immerman · · Score: 1

      Your typical spider produces many different kinds of silk, I don't think anyone is trying to replicate the sticky kind, generally they want the super-strong dragline silk.

      --
      --- Most topics have many sides worth arguing, allow me to take one opposite you.
    2. Re:I hope they remove the Sticky! by Anonymous Coward · · Score: 0

      Obligatory: Far Side

  12. Spidergoats by geekmux · · Score: 1

    Spidergoats?

    Damn, I can think of one Homer J. Simpson that's jealous as hell.

    All he has is a lame spiderpig. That's soooo 2007.

  13. Does anybody here watch/follow Frankenstein M.D.? by kram1032 · · Score: 1

    Not only do people produce large quantities of spider silk in, amongst other methods, goat milk. They also work on using this silk to essentially make bullet-proof skin. Currently what they do is put a mesh of spider silk in a petri dish and then let skin cells grow over this mesh. The result is patches of skin strong enough to withstand slow-moving bullets (e.g. pistol bullets). http://www.frankensteinmd.com/...

  14. Silksteel alloys by Atmchicago · · Score: 1

    Until quite recently, spider silk had the highest tensile strength of any substance known to man, and the name silksteel pays homage to the arachnid for good reason.

    -- Comissioner Pravin Lal ,"U.N. Scientific Survey"

    --

    You can lead a horse to water, but you can't make it dissolve.

  15. this is so old by Anonymous Coward · · Score: 0

    I remember this being done years ago with the goats. Have the patents expired and now anyone can take it up without paying?

  16. Re:Does anybody here watch/follow Frankenstein M.D by ChrisMaple · · Score: 1

    Stopping a bullet with your skin is nice, but the shock wave is still going to do a lot of damage. A bullet to the skull will produce a hail of bone fragments.

    --
    Contribute to civilization: ari.aynrand.org/donate
  17. News? by Verdatum · · Score: 2

    Is it just me or does it look like this article was written in 2006, and just happens to have a 2014 datestamp? I'm pretty sure I've read most of this information years ago.

    1. Re:News? by Verdatum · · Score: 1

      Hmm, looks like Araknitek didn't form until February 2014, so at least that much is newish. But yeah, this article does a pretty lousy job at separating out what specific developments are new compared to what aspects of the story are background.

    2. Re:News? by Ferrofluid · · Score: 1

      It's even older than that. Here's an article on the subject dating back to 1998. Jeffrey Turner was one of the early pioneers of this research, and co-founded a company, Nexia Biotechnologies, to commercialize the idea in 1993. I swear these "spider goat" articles have been popping up several times a year for the last fifteen years in various media outlets.

    3. Re:News? by Verdatum · · Score: 1

      Even TFA mentions research that goes all the way back to 1990. I'm all for progress in this field, but every time I seriously look into it, I see people who are "5-to-10 years away from practical applications" which continues to be the company line for decades on end, or companies that claim to do something truely novel, yet for some reason can't seem to get enough funding to avoid bankruptcy or support any further research. All this just reinforces the, "please tell me when something NEW happens" attitude. And they would do themselves a huge favor if they at least made an effort to not bury such a lede in a headline that sounds like old old old news.

  18. Spider goats In their natural habitat by Anonymous Coward · · Score: 0

    Spider goats In their natural habitat http://cdn-www.cracked.com/articleimages/ob/goats_tall.jpg

  19. SPIDER MAN IS REAL!!!!!!!! by jebus187 · · Score: 1

    Spider man spider man radioactive spider man!!!!!!

  20. Pick a date by Empiric · · Score: 0

    So, it's now scientifically directly false to claim that all observable biological features can be explained without reference to design.

    Looking for a proposed date at which we know design did not happen before then, to be able to make a -qualified- statement of explanation via evolutionary processes, that is, knowing the mainstream causal factors given, e.g. in classrooms, is simply, provably, scientifically false.

    What date do you like, before which we have evidence to assert biological design did not happen?

    --
    ~ Whence do you come, slayer of men, or where are you going, conqueror of space?
  21. Spider Goat. by thedarb · · Score: 1

    Spider goat! Spider goat! Does whatever a spider goat does!

    --
    This sig intentionally left blank.
  22. Wow. REALLY old news (circa 2001) by Anonymous Coward · · Score: 0

    http://www.forbes.com/global/2001/0219/061.html

  23. Spider Goat was a failure. by rahvin112 · · Score: 1

    Search for the spider goats in Google News. Last I saw they could extract the silk proteins from the milk but weren't able to combine them, they ended up with a big pile of the proteins and no way to weave them into silk. Though I believe they're still working on it there isn't high hope they will succeed. That's why they've begun talking about using silk worms, they are easy to setup (it's been done for centuries) and harvest silk and have they already have the necesary biological systems necessary to spin the proteins into silk fibers.

    1. Re:Spider Goat was a failure. by Tempest451 · · Score: 1

      Why not electrostaticly spin the fibers? http://www.ncbi.nlm.nih.gov/pm...

  24. with idiots like this running the companies... by Anonymous Coward · · Score: 0

    from TFA:

    When it was cooking in the microwave, it made a vegetal aroma that all the kids complained about,” he says. “I always told them it was the smell of money.

  25. I for one. . . by Anonymous Coward · · Score: 0

    . . . welcome our new Arachno-capric overlords!

  26. ...What? by Anonymous Coward · · Score: 0

    I thought we had game changing technology called the 3D printer? Can't we just 3D engineer any material we want now?

    I was told the game had changed, was I lied to?

  27. They're missing the point by Immerman · · Score: 1

    Indeed, I came here to say much the same - the magic of spider silk is at least as much in the "spinning" as in the protein. Silkworms will presumably make far purer silk-proteins that goats, and might (or might not) possibly even produce a slightly-stronger-than-normal silk themselves, but it won't be anywhere near the same league as true spider silk. I rather doubt micropipets could do the job either - I've gotten the impression that the spinnerets are an extremely sophisticated protein-manipulation organ, I would be very impressed if "shoving it down a stationary tube" could be made to have the same effect. Even if we're only trying to make one kind of silk instead of the half-dozen or so kinds the typical spider produces.

    --
    --- Most topics have many sides worth arguing, allow me to take one opposite you.
  28. GMO=Genetic holocaust by Eravnrekaree · · Score: 1

    This GMO stuff just keeps getting more creepy, freaky and frankensteinish. We need to ban this stuff before it causes a global ecological disaster and wrecks the planets environment or turns the place into a monstrous wasteland of deformed beasts and poisonous, cancer causing food. The dangers of GMOs have been well documented by others, including the cancer causing potential, such as in Jeff Smith's book.

  29. Still working on it by l0n3s0m3phr34k · · Score: 1

    I remember the spider silk goats from years ago. The last I heard was they had a small breakthrough in the spindle (underwater), yet hadn't yet scaled it up much. They said they where working with the FDA for muscle ligament replacements and such. I'm still waiting for my spider silk goat grappling rope.

  30. Re:Does anybody here watch/follow Frankenstein M.D by l0n3s0m3phr34k · · Score: 1

    yeah, people who only know bullet damage from TV can't comprehend the impact trauma to the underlying muscles. Even with a "bullet proof vest" without the impact plate your looking at a horrid bruise, big enough caliber might still kill you. Even with the plate it can still bruise to the point of making movement quite painful and unsteady. Oh, and it takes at least a few weeks to recover back to 100% even without actual penetration.

  31. Taylor Hebert by Anonymous Coward · · Score: 0

    Taylor Hebert is going to go out of business (warning: almost two million words of free awesome ahead).

  32. Re:Does anybody here watch/follow Frankenstein M.D by Tempest451 · · Score: 1

    Unless your skin, muscle, and bone were all reinforced with different version of fibrion (spider silk) molecules

  33. I really do not want to see Spidergoatse. by Anonymous Coward · · Score: 0

    Really. I don't.

  34. Re:Does anybody here watch/follow Frankenstein M.D by kram1032 · · Score: 1

    of course, yes. I'd assume, though, that such an impact trauma probably is better than a freely bleeding hole in your body? Not quite sure Internal bleeding is no joke either. You could probably reinforce in similar ways muscle tissue and perhaps bones too. (On the show they also mentioned super strong bone replacement, however, that'd not be living, i.e. it wouldn't produce blood plate as our bones do.)