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Woman Suffers Significant Weight Gain After Fecal Transplant
Beeftopia (1846720) writes In a case reported in the journal Open Forum Infectious Diseases, a woman suffering from a drug-resistant intestinal infection gained 36 pounds after receiving a fecal transplant from her overweight daughter. Previous mouse studies have shown thin mice gain weight after ingesting fecal bacteria from obese mice. The woman previously was not overweight. After the procedure, despite a medically supervised liquid protein diet and exercise regimen, the woman remained obese. Her doctor said, "She came back about a year later and complained of tremendous weight gain... She felt like a switch flipped in her body, to this day she continues to have problems... as a result I'm very careful with all our donors don't use obese people."
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Figure out which bacteria the obese patients have in common that the thin ones don't, and figure out a way to eliminate it.
Only eat at places run by skinny people.
This issue is a bit more complicated than you think.
Yes. http://gizmodo.com/the-secret-to-weight-loss-might-be-poop-transplants-fro-1265888152
Now you have me wondering if we can make dumb people smart, and mean people nice. We may achieve world peace through fecal transplants.
“He’s not deformed, he’s just drunk!”
When something happens and your guts flora goes out of wack, because of a previous illness, some surgery, whatever, your digestive system suffers quite a bit, and has no way to recover (those bacterias don't come out of nowhere...if 100% of them are gone, they're not coming back...).
So the only way to get them back is to transplant bacterias from someone else, to "bootstrap" your system anew. And the easiest way to get a bunch of those bacterias is in, well...yanno...
So they either take a piece and stick it in you, or they make a pill out of a little bit of it. Gross as hell, but less gross than dealing with a fucked up guts flora.
I know its a joke, but not really. At the end of the day, humans are just fairly complicated machines, or even just a big complex chemical reaction.
Pretty much everything we do comes from either training/uprising, or from some biological system or another. As time goes, we'll figure out all of the later...and statistics will take care of the former.
Will be a very boring world probably, but...
Exactly what it sounds like.
Humans have gut bacteria. These bacteria are required for the gut to function properly. In some cases a person can lose theirs following a course of really powerful antibiotics - they'll kill whatever's causing their disease, but kill all the required bacteria in their gut too. This is a bad thing: Gut without bacteria doesn't work very well and, though it's not fatal, is going to leave the patient suffering a number of unpleasant conditions. The solution is very simple though. Just take someone with a healthy bacterial ecosystem in their gut, extract a handy lump of bacteria, insert it into the unhealthy patient. The ready-made bacterial colony then takes hold there and returns things to a healthy balance. It sounds disgusting and, well, it is. But it works.
More evidence to support my hypothesis that gut flora plays games with us. All it takes is one bacteria secreting a chemical that makes us feel like crap if we don't eat the sugars or whatever it craves and secreting something else that makes us feel good when we do.
Maybe resisting that sick feeling and staying on course means the rogue organism will starve to death?
There are gut flora organisms which can't be cultured outside the gut, or even outside certain portions of the gut. We don't know what a lot of them do, but there are something like 2kg (~4lb) of them in each of us. Being quite small, each of us is vastly outnumbered on the scale that war against these beasts is basically genocide (How To Make A Vegan Explode -101).
In a world of the blind, the one-eyed man is king--and the two-eyed man is a heretic.
So that's the definition of 'humanitarian.' I always wondered about that.
It doesn't have to be all that bad. You freeze dry the feces (that can't be fun). The smelly parts go up the evaporator, mostly. Some protocols spin out the debris (yesterdays burrito bits) leaving you with some flotsam that should be mostly bacteria. You put that in an enteric coated pill (so the stomach acid doesn't clobber everything) or you shove it up the butt using one of a number of techniques (insert, so to speak, favorite joke here).
Wait a bit and see what happens.
This is a very trendy field since 1) it clearly works for a defined illness (Clostridium difficele infections) 2) has an interesting and biologically plausible mechanism(s) 3) is easy to make (see above, do not try this at home, professional driver on closed course and all that) and has virtually limitless advertising possibilities. Even aside from the Holy Grail of weight loss and 4) should be able to keep Jon Stewart, 4chan and the rest of the planet in bad jokes for quite some time.
Faster! Faster! Faster would be better!
If a fat person eats skinny people shit will they lose weight??
I don't know about that one, but having worms in your intestine can make you lose weight for sure.
See picture. It's just like a big bowl of yummy pasta!
Why boring? We've established that psychopaths are far more successful in modern society, so obviously the first thing anyone who wants the best for their children should do is have them engineered for psychopathy. Empathy is for the weak. Should make things *extremely* interesting...
--- Most topics have many sides worth arguing, allow me to take one opposite you.
We've established that psychopaths are far more successful in modern society, so obviously the first thing anyone who wants the best for their children should do is have them engineered for psychopathy. Empathy is for the weak
No, game theory tells us that sociopaths do well in a society that is primarily composed of non-sociopaths, but do not do so well in a society where they are the majority (and that society also doesn't do well as a whole).
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Here's a link to the actual study.
In brief:
Woman weighed 136 pounds, daughter weight 140 pounds. After transplant from daughter to woman, she didn't return for 16 months (according to my reading of the article). The woman had gained up to 177 pounds, while the daughter gained up to 170 pounds.
So this is more a case report than an study. Journals are used for communication between professionals. This doctor is saying, "hey, something weird happened.....it might be a coincidence (there is a lot wrong with this woman), but keep an eye out for anything similar."
"First they came for the slanderers and i said nothing."
The child's intestine gets colonized during childbirth. That's been discovered to be one of the problems with Caesarian section, in fact. The baby's large intestine doesn't get the proper bacterial colonization.
Did you even bother to read the article? The woman's eating habits and calorie intake were carefully measured and she gained weight despite not changing anything. I've lost 35 lbs with exercise, but despite spending almost 100 minutes and 1100 calories a day, I still can't get rid of the last 5-10 lbs of flab. It doesn't matter how little I eat.
You may find this article informative.
Calorie measurements of food are just estimates, the particulars vary. The gut bacteria of fat people absorb more of the available energy than that of skinny people, but our measurements of the calories in food aren't necessarily the max amount that could be absorbed.
To put it simply, fat people get more calories from the same food than skinny people, regardless of how many calories the label says the food has.
That only applies when you're dealing with basically an ISO Standard nutrient processing system on a lab-made nutrient slurry--basically, lab mice on lab block.
Basically, gut bacteria are actually a pretty essential part of processing nutrients, and in some cases the actual source of much of them. Certain types of problems basically will leave you incapable of properly processing parts--for example, with my aunt certain kinds of foods are now pretty much processed directly into fats, and the body is quite capable of taking part of those 3000 Calories' worth of warm-blooded flesh and using that to sustain it when the 2000 Calories of the food intake is being mostly stored. (And yes, the capitalization matters: nutrition uses the kilocalorie, actually, and in a confusing fit of non-standard metric renders it Calorie instead. Either way, the amount of error due to rounding introduced into the values is left as an exercise for the reader.)
This can, however, be caused by things like a food intolerance or a metabolic dysfunction, and one of the basic tests to see if the person's obesity is a symptom is to, well, cut the caloric intake while maintaining the same levels of activity and see if weight loss happens. The wide range of things it's a symptom of--from things as amazingly cheap & easy to treat such as thyroid disease to those essential to catch early like cancer--are such that failing to check the cause is like...well...failing to check to see if the computer's problem is that it's not turned on.
I am not going to take any shit from you.