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Researcher Developing Tattoo Removal Cream

BarbaraHudson writes During tattooing, ink is injected into the skin, initiating an immune response, and cells called "macrophages" move into the area and "eat up" the ink. The macrophages carry some of the ink to the body's lymph nodes, but some that are filled with ink stay put, embedded in the skin. That's what makes the tattoo visible under the skin. Dalhousie Uiversity's Alec Falkenham is developing a topical cream that works by targeting the macrophages that have remained at the site of the tattoo. New macrophages move in to consume the previously pigment-filled macrophages and then migrate to the lymph nodes, eventually taking all the dye with them. "When comparing it to laser-based tattoo removal, in which you see the burns, the scarring, the blisters, in this case, we've designed a drug that doesn't really have much off-target effect," he said. "We're not targeting any of the normal skin cells, so you won't see a lot of inflammation. In fact, based on the process that we're actually using, we don't think there will be any inflammation at all and it would actually be anti-inflammatory."

36 of 164 comments (clear)

  1. Found the perfect way by hcs_$reboot · · Score: 3, Insightful

    No tattoo at all in the first place.

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    Slashdot, fix the reply notifications... You won't get away with it...
    1. Re:Found the perfect way by Bing+Tsher+E · · Score: 2

      If we can come up with technology that removes tattoos, permanently and easily, it will eradicate the tattoo blight.

      Tattoos are a cry out for something permanent. "I have important messages to send, and it is PERMANENT! I will ALWAYS feel this way." Which leads to ugly blight patches on middle aged skin.

      Of course, it could just push the self-mutilation envelope even further, i.e. piercing and radical body mod. We haven't gotten to 'Dr. Adder' yet.

    2. Re:Found the perfect way by TWX · · Score: 4, Insightful

      A lot of things are much easier for individuals to judge in hindsight than at the time they make those decisions.

      Everything from teenage angst to pornography would be entirely different if more people foresaw the personal ramifications of their decisions.

      --
      Do not look into laser with remaining eye.
    3. Re:Found the perfect way by PPH · · Score: 4, Interesting

      Why would you want something that is not permanent?

      I know a porn star who has some prominent tattoos that are not permanent (possibly Henna that she has re-inked). They are her trademark, but also an exit strategy from the porn biz. Retire, take a vacation to let the ink fade. Then she can go out in public as the woman who looks like that porn star, but without the tats.

      --
      Have gnu, will travel.
    4. Re:Found the perfect way by ganjadude · · Score: 2

      I have a number of tattoos, all covered by a t shirt and long pants btw. but anyway I got my first one 12 years ago now and my method seems to work for me.

      If i think i want some ink, I sleep on it. not for a day, not for a week, but at least a year. If I still want that same ink in a year, I get it. Ive decided against no less than 20 designs by doing that, and i currently have 5 designs (although more sessions because i tend to add to what I have rather than using new locations)

      --
      have you seen my sig? there are many others like it but none that are the same
    5. Re:Found the perfect way by ganjadude · · Score: 2

      Tattoos are a cry out for something permanent. "I have important messages to send, and it is PERMANENT! I will ALWAYS feel this way." Which leads to ugly blight patches on middle aged skin.

      thats one reason, but not the only, or even mostly used reason for getting ink

      --
      have you seen my sig? there are many others like it but none that are the same
    6. Re:Found the perfect way by Reziac · · Score: 2

      "...a permanent reminder of a temporary feeling..."
          -- Jimmy Buffett

      --
      ~REZ~ #43301. Who'd fake being me anyway?
  2. Re:Inking your skin... by Anonymous Coward · · Score: 3, Interesting

    Getting a tattoo may or may not be stupid, it depends on the circumstances. But I'm having a hard time imagining a situation where having a tattoo removed is stupid.

  3. Not Sure If Good Or Bad by Anonymous Coward · · Score: 2, Interesting

    On the plus side, it makes it much easier to get rid of that tattoo I got last night while drunk.

    On the minus side, it makes it much easier for someone to remove your tattoo in your sleep.

  4. Re:Inking your skin... by Noah+Haders · · Score: 4, Informative

    Got a tattoo in college. I really liked it for about 10 years, then I decided I was done with it and wanted to move on to another phase of my life. So I did laser removal, and I would say it's 99% gone. You'd have to be pretty close and know where to look to find any trace of it. In short, I rubbed a thousand dollars on it and it came right off!

  5. Why? by bigdavex · · Score: 4, Funny

    No ragrets

    --
    -Dave
  6. Nothing could possi by bosef1 · · Score: 2

    So instead of having the tattoo ink spread out in a relatively benign part of my dermis, instead I'll concentrate it in my lymph nodes. It feels like this could cause problems. How does the body clear the ink from the lymph nodes? Is it broken down; or does it just stay there, possibly clogging the nodes, or acting as an irritant and maybe causing a long-term cancer risk.

    Maybe we could also turn the research around. If there were ways to make less digestable or less "attractive" inks, or to pre-train the macrophages to ignore the ink particles, you could make longer-lasting tattoos that need less ink to apply and fewer touchups.

    1. Re:Nothing could possi by Ungrounded+Lightning · · Score: 2

      So instead of having the tattoo ink spread out in a relatively benign part of my dermis, instead I'll concentrate it in my lymph nodes.

      I was under the impression that the macrophages would then be broken down and their contents recycled or disposed of - that this migration was just one step in the process. Is this not true?

      There are a lot of macrophages migrating to the lymph nodes over a lifetime. If they just went there, died, and left their contents the nodes would swell with age and never shrink - yet this doesn't seem to happen.

      --
      Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
  7. Re:Inking your skin... by phantomfive · · Score: 2

    Yeah, now that they're removable, the drunk tats you see on college students are going to be a lot more inane.

    --
    "First they came for the slanderers and i said nothing."
  8. Re:Unfortunately.... by russotto · · Score: 4, Insightful

    Probably living in a forest, breathing fresh air, eating natural food and drinking source water is less carcinogenic?

    Trees pump out all sorts of carcinogenic crap. The Great Smokey Mountains aren't smokey from man-made pollution or fire, after all. If the canopy isn't too heavy, living outdoors means susceptibility to skin cancer. Natural food, especially plants also contains all sorts of toxins. And water in nature can contain lead and arsenic and kill you too. But if you live like that, your chance of cancer might be cut down by getting bitten by a snake or attacked by a wolf or a bear or something, or just hypothermia.

  9. IF true... by fyngyrz · · Score: 4, Interesting

    This could help out a lot of misguided kids who went and uglified themselves, can't figure out why they keep getting rejected for jobs, can't wear a nice dress without looking like an octopus puked on them, or otherwise have defecated all over their skin.

    Some ex-prisoners, too. Nothing like prison tats to mark you as an outcast, with all the social and financial downsides that involves (besides the complete drop to permanently lowest-class unemployable for most, I mean.)

    Most tats -- not all, a very few are actually amazing bits of art -- aren't worth getting, and even fewer are worth keeping, confirmation bias and pure stubbornness notwithstanding.

    This stuff works, though, and it'll change the entire nature of the industry. The idea that these aren't permanent will change the motivation and the sense of commitment, which could cut down on some of the outright stupidity. And for those who go forward, they'd no longer be outright screwing themselves when the styles change, or they run into one of the (many) bosses who view them as a mark of abject stupidity. Even that outlook might change, based on the knowledge that they aren't permanent -- I could see some saying, "You can work the returns counter as soon as you get 'John luvz Mary' off your forehead."

    --
    I've fallen off your lawn, and I can't get up.
    1. Re: IF true... by kelemvor4 · · Score: 2

      Or we could stop having superficial bosses with superficial ideas. They tend to be dying off at faster than replacement rates so perhaps there's hope for us yet. I can't wait for the last of the suit and tie set to die off.

      BTW, I have no tattoos and don't especially like them. I just like corporate attitudes a lot less.

      Because nothing says "I make good decisions" like permanent marks all over the body, right?

    2. Re:IF true... by wbr1 · · Score: 5, Interesting

      ...Some ex-prisoners, too. Nothing like prison tats to mark you as an outcast, with all the social and financial downsides that involves (besides the complete drop to permanently lowest-class unemployable for most, I mean.)

      You do not need prison tats for that. A background check will do sufficiently. That said, I m an ex felon, with some tats from before and during my time. I have a fair job at a small local IT company, and am building my own business. However, it has and continues to be a very hard struggle, and I can see why many give up and go sling dope or rob again.

      --
      Silence is a state of mime.
    3. Re: IF true... by Opportunist · · Score: 2

      I'd rather have a CEO with "Backstreet Boys forever" tattooed on his forehead than one who has already sunk 2 companies and promises that everything's going to be all different this time.

      But very obviously sinking companies is less of a crime than loving the wrong boyband in the CEO business if the track record of many of them is any indication. I see few with ZZ-Top tattoos, but a lot of them sinking company after company and yet still being hired again.

      --
      We used to have a Bill of Rights. Now, with the rights gone, all we have left is the bill.
    4. Re:IF true... by narcc · · Score: 4, Funny

      When people say "six-figures" they don't generally count the two after the decimal point.

    5. Re: IF true... by __aaltlg1547 · · Score: 4, Interesting

      Exactly. I can teach you to do your job, but I can't teach your tats to go away. Until now?

      If this works, you'll see employers requiring their employees to remove tats.

    6. Re: IF true... by Darinbob · · Score: 4, Insightful

      It's not just a corporate attitude. It turns off a lot of people. Which is ok for young people who don't give a damn what anyone but their current love interest thinks. But when real life starts to intervene as one gets older, there are a lot of people who regret the ink.

    7. Re:IF true... by fyngyrz · · Score: 3, Interesting

      You do not need prison tats for that. A background check will do sufficiently.

      I wasn't talking about jobs. There, I agree, those doors become more difficult to get through no matter what once you have a record, as a felon or even just an arrest record.

      I was referring to the potential classing in social situations visible prison tats provide; they can earn the bearer anything from a spitburger to refusal of housing without any formal checking at all. As can any other form of voluntary or involuntary revelation of wrongdoing, or accusation of wrongdoing. It's the same silent prejudice that the US social structure has always indulged itself with. Any non-white can relate.

      Good to hear you're building your own business. It worked for me, hopefully it will for you as well.

      --
      I've fallen off your lawn, and I can't get up.
    8. Re: IF true... by rtb61 · · Score: 2

      Which makes the tattoo removal cream interesting in application. Will it lead to more people walking around as billboards for other people's art work or less. So the ability to easily remove other people's art work, will that lack of commitment to other people's art lead to more people willing to make themselves billboards or will it lead to less people ie no commitment to other peoples art so why bother. You can guess why I never, I just didn't get why I would display someone else's art, when I could not really see it, I mean if you tattoo yourself sure, display you talents to other people but when someone else turns you into their billboard what are you really achieving.

      --
      Chaos - everything, everywhere, everywhen
    9. Re: IF true... by drkim · · Score: 2

      Exactly. I can teach you to do your job, but I can't teach your tats to go away. Until now?

      If this works, you'll see employers requiring their employees to remove tats.

      Unfortunately, you won't see employers doing this...

      You'll see tatted people still not getting the job in the first place.

      This just gives them a way to remove the ink; once they figure out they aren't getting any call backs.

    10. Re: IF true... by mreed911 · · Score: 2

      I have an employer that requires visible tattoos be covered. If this means wearing a turtleneck undershirt when it's 105F in the summer, so be it.

  10. Re:Inking your skin... by Noah+Haders · · Score: 4, Informative

    I don't think so. When I was a college student it never occurred to me that I would want to remove the tattoo. It perfectly suited me, and I didn't understand that I would change over time and outgrow the tattoo. This is how kids think. They think that the way things are will remain forever. Forever young!

    Some advice for people considering this path -- only get a black ink tattoo. They are much easier to remove than a colored tattoo. The laser has to be tuned to the wavelength of the ink color, so if you have a tattoo that is black, red and green then you need to hit it with three separate lasers and the way one color responds may be different than other colors.

    Also, set your expectations. By the time my treatments were complete (6 treatments, each 6 weeks apart), the tattoo was about 2/3 faded. then my body flushed the rest out over the following year. So I can't complain!

  11. On fashion and graffiti by Marginal+Coward · · Score: 3, Insightful

    I keep wondering what will happen when the fashion for tattoos fades away but the tattoos themselves don't. The (mainstream) people who get tattoos don't seem to realize that today's fashion generally looks stupid after a decade or so. But unlike other fashions, tattoos are intended to be permanent. In fact, that's the primary selling point. Fortunately, if necessity is the mother invention, maybe technology like that described in TFA will provide answers.

    Another thing in this category is gauges. Even if one assumes that people with gauges look cool now, they're unlikely to look cool in a decade. (Witness bell bottom pants from the 1970s as seen from the 1980s or later.) Won't they look stupid in the future with either a gauge or a giant hole in their dangling earlobes?

    As an old timer, the whole idea of body graffiti seems a bit strange to me. Usually, graffiti is applied to someone elses' property, not your own. At best, graffiti is art, but at worst, it is just vandalism. So why would you vandalize the single-most valuable piece of property you own - your body?

    1. Re:On fashion and graffiti by alleycat0 · · Score: 2

      ...which is why, according to The Guardian, "one of the fastest-growing cosmetic procedures in the UK is repairing stretched earlobes" (http://www.theguardian.com/lifeandstyle/2014/oct/19/cosmetic-surgeons-repair-stretched-earlobes).

      --
      I am not a number - I am a free man!
  12. Given all the tattoo hate here by TeknoHog · · Score: 4, Insightful

    I'm a math/science guy, and I have math symbols on my arms. If I ever regret my affection towards math and science, I might as well have some skin torn off.

    Besides, the capital Sigma works great whenever somebody asks me "Are you series?".

    --
    Escher was the first MC and Giger invented the HR department.
    1. Re:Given all the tattoo hate here by Jack+Griffin · · Score: 3, Insightful

      I'm a math/science guy, and I have math symbols on my arms. If I ever regret my affection towards math and science, I might as well have some skin torn off.

      Besides, the capital Sigma works great whenever somebody asks me "Are you series?".

      Not sure if the first part was also part of the joke. But as someone older than 30, I can tell you that you probably won't regret your affection for maths, but you will probably (hopefully you will grow up one day) regret thinking that the idea of drawing things that you like on your skin is going to impress anyone.
      Looking like a cool 20 year old is cool when you're 20. Not so much when you're 40.

    2. Re:Given all the tattoo hate here by TeknoHog · · Score: 2

      Not everybody is drawing on their skin to impress someone.

      This. My signs are rarely visible, even most t-shirts cover them, and I don't exactly go around flaunting them. It's a personal thing that tells something about me, for those who like to know. It's also a kind of joke about the perceived disjoint between those who have tattoos and those who work in education or research. That said, I've seen a surprising amount of ink in the teachers' lounges, and one of my most inked friends is an elementary school teacher; the university people seem more conservative than teachers in this sense, in my experience.

      Some people might prefer an expensive suit or a fancy car to maintain a certain kind of image, and they don't seem to get the same kind of hate -- though that kind of image is usually associated with a status that attracts haters for other reasons.

      It's pretty hard to go about your life not giving any kind of impression. If you avoid giving one at all, then chances are that others will come up with all kinds of false impressions.

      --
      Escher was the first MC and Giger invented the HR department.
  13. Would you like an EAR to go with that, sir? by TiggertheMad · · Score: 3, Funny

    Too true. Why just think of it, Mike Tyson might be able to get a job a McDonalds once he got rid of his freaky face tattoos...

    --

    HA! I just wasted some of your bandwidth with a frivolous sig!
  14. Good for other things than tats? by Ungrounded+Lightning · · Score: 2

    If the macrophages do this with tattoo ink, they no doubt do it with other things, as well.

    I wonder if using this cream to remove ALL the dead-macrophages-loaded-with-junk from the skin will result in effectively "younger" skin?

    --
    Bantam Dominique roosters crow a four-note song. Once you've heard it as "Happy BIRTHday" you can't NOT hear it that way
    1. Re:Good for other things than tats? by rmdingler · · Score: 4, Funny

      If the macrophages do this with tattoo ink, they no doubt do it with other things, as well.

      I wonder if using this cream to remove ALL the dead-macrophages-loaded-with-junk from the skin will result in effectively "younger" skin?

      If your hypothesis is proven accurate, the new product will remove ink and years off your appearance.

      Cha-ching!

      The only pharmaceutical product imaginably more profitable would be a weight loss cream that makes your dick hard.

      --
      Happiness in intelligent people is the rarest thing I know.

      Ernest Hemingway

  15. Ever see a tattoo after 30+ years? by Required+Snark · · Score: 4, Interesting
    If you live long enough, you tattoo will turn into a shapeless blob of ill defined colors.

    I had a friend who was in the Marines when he was in this late teen years in the early 1950's. In the mid 80's he showed it to me. I was just a round blotch of blue/gray.

    Tattoo ink migrates over time. Muscle and skin age and change their shape. It's guaranteed that a tattoo will not stay the same as time passes. It will only look worse.

    By the way, the reason that sailors and marines get tattoos is in case they are blown to pieces. A distinctive tattoo on a limb makes it more likely that that body part will be recognized by the survivors. That's why there are often tats on different limbs.

    Whens someone gets a tat, and then says that it's to mark a point in their life, I often wonder if that means they are planning for future senility, or being blown apart. Just wondering...

    --
    Why is Snark Required?