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Scientists Insert a Synthetic Memory Into the Brain of a Sleeping Mouse

the_newsbeagle writes: Scientists are learning how to insert fake memories into the brain via precise electrical stimulation (abstract). In the latest experiment, they gave sleeping mice a synthetic memory that linked a particular location in a test chamber to a pleasurable sensation. (At least they gave the mice a nice memory.)

The researchers first recorded the electrical signals from the mice's brains while the mice were awake and exploring the test chamber, until the researchers identified patterns of activity associated with a certain location. Then, when the mice slept, the researchers watched for those neural patterns to be replayed, indicating that the mice were consolidating the memory of that location. At that moment, they zapped a reward center of the mice's brains. When the mice awoke and went back into the chamber, they hung around that reward-associated location, presumably expecting a dose of feel-good.

68 of 111 comments (clear)

  1. I know Kung Fu by nobuddy · · Score: 4, Interesting

    Very early in the research, but man would this be a cool alternative to education. Take a nap, ready to start your PhD Thesis.

    1. Re:I know Kung Fu by Zeromous · · Score: 2

      Something to do during these oppressively long meetings. Maybe we'd even have less if people weren't talking and using the wasted time to make themselves actually smarter rather than just sounding smarter!

      --
      ---Up Up Down Down Left Right Left Right B A START
    2. Re:I know Kung Fu by ckatko · · Score: 5, Interesting

      Well, that's not really what they said. Far out, that may be possible, but what they've done is not create memories but help the brain highlight important information. So you would still have to go to class, and still have to pay close attention to ensure your short-term doesn't toss it away (or you didn't listen to begin with). This would only force your brain to remember it. Side-effects include sexual arousal during all recalled memories.

      I call the term "brain boner". You heard it first here folks!

      What I find most interesting about brain research is 1) The possibility to communicate with non-humans and 2) the immediate ability of us to realize how cognitive our fellow animals are. We might find out we've been committing atrocities against intelligent lifeforms at an unfathomable scale. On a less disturbing advantage: 3) I'm a bird and I'm flying! Oh my Gooooddd! and 4) Better understanding of memory and learning. We might find out that the brain has a limit and we've all been bouncing off that limit without realizing it meaning filling your head with junk information is dangerous. Or that there's a certain, most effective way to learn that we've all missed. The future fills me with an awe-filled fear and excitement.

    3. Re:I know Kung Fu by fahrbot-bot · · Score: 1

      Something to do during these oppressively long meetings.

      Just great. Take a nap, wake and exclaim, "I know TeamForge" - as River Tam put it, "Put a bullet to me. Bullet in the brain pan. Squish."

      --
      It must have been something you assimilated. . . .
    4. Re:I know Kung Fu by geekmux · · Score: 2

      Very early in the research, but man would this be a cool alternative to education. Take a nap, ready to start your PhD Thesis.

      Well I'm glad your memory is recalling the feel-good learning curves that were blown away in The Matrix.

      I was thinking more along the lines of Total Recall, with governments using this kind of technology as a weapon, not a learning tool.

      We don't know the classified side of this research. At all.

    5. Re:I know Kung Fu by Mr+D+from+63 · · Score: 1

      Well, that's not really what they said. Far out, that may be possible, but what they've done is not create memories but help the brain highlight important information...

      I suppose they could claim they created the memory of the pleasant sensation, but I think at most what they did was create an association, not a memory, or like you say trigger something that locks the memory in.

    6. Re:I know Kung Fu by myowntrueself · · Score: 1

      Very early in the research, but man would this be a cool alternative to education. Take a nap, ready to start your PhD Thesis.

      Or, alternatively, plant memories of sexual abuse in children so you can do away with your political opponents (the premise of Blake's 7 btw).

      --
      In the free world the media isn't government run; the government is media run.
    7. Re:I know Kung Fu by war4peace · · Score: 1

      Corporations will use their resources to insert memories into your brain and make you LOVE those oppressive meetings

      --
      ...gis sdrawkcab (usually not responding to ACs; don't bother posting as AC)
    8. Re:I know Kung Fu by Anonymous Coward · · Score: 1

      Very early in the research, but man would this be a cool alternative to education. Take a nap, ready to start your PhD Thesis.

      Well, this is more like making you associate something with pleasure. You can probably not learn new things with this method.
      But if you kidnap someone you can probably change that fear of you into love when they sleep.

    9. Re:I know Kung Fu by earthminion · · Score: 1

      Right along with waking up and saying "I believe in the *insert name* party leading the country" and "two plus two equals five".

    10. Re:I know Kung Fu by Jeremiah+Cornelius · · Score: 2

      Was the "memory" implant the image of an electric sheep? We can remember it for you, wholesale.

      --
      "Flyin' in just a sweet place,
      Never been known to fail..."
    11. Re:I know Kung Fu by cytg.net · · Score: 1

      yes, conditioning of the mind in every aspect imaginable. what could possibly go wrong..

    12. Re:I know Kung Fu by cytg.net · · Score: 1

      I assume you refer to ads ?

    13. Re:I know Kung Fu by war4peace · · Score: 1

      Nope. I refer to you, going to work and loving everything that you used to hate, because there's this thing above your head that makes you take a nap as soon as you sit on your chair... and when you wake up, you'll like your boss, your retarded co-workers and every lil' shit that's thrown at you during your workday there.

      --
      ...gis sdrawkcab (usually not responding to ACs; don't bother posting as AC)
  2. You Can't Fool Me! by fuzzyfuzzyfungus · · Score: 1

    The obvious reason why this line of research is 'starting' now is that it is only with contemporary solid-state RF hardware that HAARP's sinister mind control can be miniaturized sufficiently for use on rodents in the laboratory, rather than mixed nuts worldwide.

    1. Re:You Can't Fool Me! by Prune · · Score: 1

      rather than mixed nuts worldwide

      http://i0.kym-cdn.com/photos/i...

      --
      "Politicians and diapers must be changed often, and for the same reason."
  3. Not about learning... by Etherwalk · · Score: 1

    It's not about learning, it's about habits. If you develop the tech for people, you can stimulate the reward centers for your own brain when consolidating memories of productive behaviors.

    1. Re:Not about learning... by hey! · · Score: 4, Insightful

      Developing habits is arguably the most important form of education there is.

      It's not just about eating your veggies and going to the gym; habits intrude on things which we normally think of as the domain of rational thought. If you hear somebody who disagrees with you do you rationally weigh his arguments or automatically dismiss them? What determines which of these alternatives you choose is habit.

      --
      Post may contain irony: discontinue use if experiencing mood swings, nausea or elevated blood pressure.
    2. Re:Not about learning... by Anonymous Coward · · Score: 1

      Over time, this may end up being a cure for severe drug addictions, or just a way to get consumers to buy more. Interesting times we live in...

  4. BWAAAAAAH by mwn3d · · Score: 1

    Cue loud horn section from "Inception"

  5. Just like in Men In Black by smooth+wombat · · Score: 2

    (At least they gave the mice a nice memory.)

    First when K flashes Beatrice after she saw her "husband" inhale the sugar water, and later at the morgue, when K instructs the clean up crew to give the coroner a happy memory.

    --
    We will bankrupt ourselves in the vain search for absolute security. -- Dwight D. Eisenhower
    1. Re:Just like in Men In Black by Darinbob · · Score: 1

      A nice memory for the mouse, but... The mice are hanging around that part of the maze waiting for something good to happen. Now they're just disappointed and more suicidal than ever.

  6. Should've by Caffeinebot · · Score: 1

    worn that tinfoil hat I gave you.

  7. I remember this story too by schneidafunk · · Score: 1

    It's the beginning of Pinky and the Brain.

    --
    Some people die at 25 and aren't buried until 75. -Benjamin Franklin
  8. Injecting memories by spacepimp · · Score: 2

    Things like this will never get exploited by opportunistic Intelligence Agencies.

    Let's sit back and watch them scramble over themselves to justify why they need this tech.

    Yes slightly offtopic, but I bet they are funding the research.

    1. Re:Injecting memories by thieh · · Score: 1

      Or remotely cheating at chess, exams, interviews, or even remote human espionage. The possibility is endless.

    2. Re:Injecting memories by Pav · · Score: 1

      They're certainly interested eg. Rebecca Saxe. Yes, she explicitly says the pentagon has called her, though she says she's not returning the calls (see the first question asked at the end of this talk). I guess that's not where she is getting her funding.

    3. Re:Injecting memories by spacepimp · · Score: 1

      Pav.. Thanks for the kink.

    4. Re:Injecting memories by spacepimp · · Score: 1

      link.. dammit

  9. Pretty much by NotFamous · · Score: 1

    That pretty much sums up my dating life.

    --
    Some settling may occur during posting.
  10. That's not really a memory... by SuperKendall · · Score: 5, Insightful

    It doesn't seem like what they did is really creating a "synthetic memory". It's taking an existing memory, and attaching (or perhaps even just re-enforcing) an emotion to it...

    The memory of the place is the same, they just remember enjoying it more than they did at the time.

    As a human you could do the same thing by visiting a famous place, then reading a really good story set there. Your own recollections of the place would have a fonder cast if you were even more excited about having been there.

    --
    "There is more worth loving than we have strength to love." - Brian Jay Stanley
    1. Re:That's not really a memory... by Anonymous Coward · · Score: 1

      sigh, yup, a synthetic reinforcement not a memory. Rather easier to accomplish. I suppose they have a false 'memory' of liking it...

      At least our click-bait headlines are still 1st class.

    2. Re:That's not really a memory... by ArsonSmith · · Score: 1

      the mouse just said, "Whoa, I know kung-fu."

      --
      Paying taxes to buy civilization is like paying a hooker to buy love.
  11. Presumably? by jkyrlach · · Score: 3, Insightful

    Wake me when they can zap a mouse and it can get to someplace it's never been before.

  12. On the "Right To Be Forgotten" by mi · · Score: 2

    This, along with the already known way to simply wipe-out certain memories, can go a long way towards establishing the "Right To Be Forgotten". Your ex, for example, may be able to obtain a court order for you to undergo the procedure to remove your memories of all the good times you had together...

    Or, if that seems too draconian, have those memories replaced by your taking a hike or flying a kite...

    --
    In Soviet Washington the swamp drains you.
    1. Re:On the "Right To Be Forgotten" by ckatko · · Score: 1

      > Your ex, for example, may be able to obtain a court order for you to undergo the procedure to remove your memories of all the good times you had together...

      While that's an interesting plot for a Sci-Fi story, forcing someone to modify their body would amount to corporal punishment.

      That's not to say governments might not abuse this (abduct you, get you to leak info, and erase they were ever there, Men in Black style), but your ex-wife will not be afforded such luxuries.

      On the other hand, even if the government can erase MY memory, they can't erase everyone's memory, photos and video of my abduction and the acts they made commit. As violated as I would feel, the dark actions of the government wouldn't magically disappear. Which means it wouldn't be very useful for them in most circumstances except some form of Invasion of the Body Snatchers.

    2. Re:On the "Right To Be Forgotten" by mi · · Score: 1

      While that's an interesting plot for a Sci-Fi story, forcing someone to modify their body would amount to corporal punishment.

      As long as it is not cruel, it will be argued, it is fine... Besides, I'm not talking criminal punishment — you may find yourself "voluntarily agreeing" to a memory wipe in exchange for being allowed to see your children after divorce.

      can't erase everyone's memory, photos and video of my abduction

      Yes, you'll know you two once had fun together, but you would not be able to recall any of the details...

      Which means it wouldn't be very useful for them in most circumstances except some form of Invasion of the Body Snatchers.

      How about erasing classified information from the heads of retiring (or fired) spooks — or even journalists? That would be useful for governments and can (will!) be made a condition for access to classified information.

      Companies may also make it a condition for employment, that whatever you learned on the job be wiped out, should you decide to leave...

      --
      In Soviet Washington the swamp drains you.
    3. Re:On the "Right To Be Forgotten" by Whorhay · · Score: 2

      Sounds like a twist on the plot of Eternal Sunshine of the Spotless Mind. In that story the premise is that people pay for their own memories to be earased so they can forget a lost love. I recommend that people watch it whenever it comes up in conversation.

    4. Re:On the "Right To Be Forgotten" by jeffb+(2.718) · · Score: 1

      Companies may also make it a condition for employment, that whatever you learned on the job be wiped out, should you decide to leave...

      Gosh, I'm surprised nobody ever thought of that.

    5. Re:On the "Right To Be Forgotten" by Prune · · Score: 1

      what he did was commanded in the old testament

      The New Testament supersedes the Old Testament. Troll better next time.

      --
      "Politicians and diapers must be changed often, and for the same reason."
  13. the people can't be trusted with this by Narcocide · · Score: 1

    Or you could just... you know... remotely compel everyone in a 2 mile radius to buy your pizza.

    1. Re:the people can't be trusted with this by thieh · · Score: 1

      You sure after eating all those pizzas you won't die from obesity-related problems? Even if you change it to sexual favours you might still get STD's. Better just stick to everyone giving you a few dollars every now and then.

    2. Re:the people can't be trusted with this by ArcadeMan · · Score: 1

      There is a precedent of such technology being used in Italy, decades ago. It was a bit more painful than this new method though.

    3. Re:the people can't be trusted with this by Anonymous Coward · · Score: 1

      Your sentence could be read either way. Your failure was no big deal. Criticizing someone else about your poor writing is where you became obnoxious.

    4. Re:the people can't be trusted with this by bkcallahan · · Score: 1

      It's called marijuana...

    5. Re:the people can't be trusted with this by Narcocide · · Score: 1

      No, obnoxious is being so damned anxious to insult someone that you totally miss the context of the original statement, rendering your crass remark nonsensical, and then getting your friends to mod them down and replying anonymously because you still after all that feel you need to get the last word in all the time.

  14. Clockwork Orange? by Qzukk · · Score: 2

    Why only when they remember bad things? After all, if they are a Bad Person(TM) then they don't deserve to do the things they enjoy like listening to Beethoven.

    --
    If I have been able to see further than others, it is because I bought a pair of binoculars.
    1. Re:Clockwork Orange? by Anonymous Coward · · Score: 1

      Yeah, no kidding. Fucking misanthropes. Change "smoking or taking drugs" to "feeling sexual attraction to someone of the same sex" and see how monstrous it sounds.

  15. we know so little... by canada_dry · · Score: 1

    ...about how the brain consolidates memories in sleep, that, it's entirely possible that the brain organizes things in some order of least to most pain/fear. So... by zapping the pleasure center it may have actually turned the rest of the memory into a terrifying hell.

  16. Oh, that explains it. by 140Mandak262Jamuna · · Score: 1, Interesting

    OK, now it makes sense. This is probably how Brian Williams and Bill O' Reilly came to believe in his own death defying ordeals in the course of news reporting.

    --
    sed -e 's/Chuck Norris/Rajnikant/g' joke > fact
  17. Stupid Mice by Anonymous Coward · · Score: 3, Funny

    So stupid. Can you imagine hanging around a place waiting for a pleasure signal? Animals are so... wait a second, got to check the FaceTwitterSlashFark feed... nothing new, darn. Anyhow, animals are so... ooh, new update!

  18. Patton Oswalt by ThatsNotPudding · · Score: 1

    "Science: we're all about _coulda_ not about _shoulda_"

    No doubt quite a few despots and TLAs are following this news closely.

  19. Commercial applications by sreever · · Score: 1

    Think of the Commercial applications! Kids hate peas? zap! they love 'em. McDonald sales down? Zap! New definition of 'Happy Meal'.

  20. Rehab... by Etherwalk · · Score: 1

    And think about the potential for changes to rehab...

  21. Exercise by sandytaru · · Score: 3, Interesting

    Can someone zap the pleasure centers in my brain while I'm looking at a picture of a treadmill? Or better yet, am ON a treadmill?

    --
    Occasionally living proof of the Ballmer peak.
    1. Re:Exercise by sandytaru · · Score: 1

      I was being facetious. I permit myself some free reading time while on the treadmill, and eat a tasty protein bar as my reward for a workout (those things are like candy bars, but I guess with more vitamins.) Despite this, I'd still rather not go to the gym every day because it's such a bother. Especially now that the weather is warming up where I live. I'd much rather go on a hike, or do exercise disguised as something fun.

      --
      Occasionally living proof of the Ballmer peak.
  22. Sounds familiar by Marginal+Coward · · Score: 2

    Didn't /. run an article on this before? Wait a minute, am I maybe part of the experiment...?

  23. 4 lights by Anonymous Coward · · Score: 1

    I one up your TWO...WEEKS with my "There are FOUR LIGHTS!"

  24. ready...get set... by CosaNostra+Pizza+Inc · · Score: 1

    Que MIB neuralizer and Total Recall jokes.

  25. The Pleasures of Paying Taxes by pubwvj · · Score: 3, Interesting

    The IRS is funding this research with the hope of getting tax payers to look forward to paying their taxes, more often, larger, bigger, huger! Pretty soon you'll want to shovel your money into the IRS pockets so that you can feel that pleasure. It will be better than sex, better than chocolate. There will be a resulting reduction in world obesity and population.

  26. Greg Bear and Peter F. Hamilton must be smiling by Hussman32 · · Score: 1

    Greg Bear had this ability as central plot points in Eon and Eternity, and Peter F. Hamilton took it much deeper in Pandora's Star and Judas Unchained.

    If you dream it, it will come.

    --
    "Who are you?" "No one of consequence." "I must know." "Get used to disappointment."
    1. Re:Greg Bear and Peter F. Hamilton must be smiling by Prune · · Score: 1

      Too bad memory erasure tech is still too immature to remove memories of his dastardly works and the time I wasted reading them from my brain. Talk about unoriginal plots and a million cliches in every story

      --
      "Politicians and diapers must be changed often, and for the same reason."
    2. Re:Greg Bear and Peter F. Hamilton must be smiling by Hussman32 · · Score: 1

      Hamilton or Bear? If I were guessing, Hamilton (although I like his work).

      --
      "Who are you?" "No one of consequence." "I must know." "Get used to disappointment."
    3. Re:Greg Bear and Peter F. Hamilton must be smiling by Prune · · Score: 1

      I didn't read any Hamilton as I was into science fiction, not space opera.

      --
      "Politicians and diapers must be changed often, and for the same reason."
  27. Hasn't corporate America been doing this already? by martinfb · · Score: 1

    Well, perhaps not with outright electrical zaps to the brain, yet with other means like a deluge of mind bashing TV ads? The way that ads target aspects of human psych not related to the product being sold seems to be a similar tactic to convince one to buy a product; which seems to be unduly offensive and unethical. THIS is an area that needs severe regulation.

    --


    Self-importance and self-indulgence is the root of ALL evil.
  28. So there's hope for Congress? by kmoser · · Score: 1

    Imagine how smart the average Congressperson would be if scientists injected them with synthetic memory every time they were sleeping.

  29. Re: Greg Bear and Peter F. Hamilton must be smilin by Hussman32 · · Score: 1

    Okay, I'll bite. Who writes science fiction that you like?

    --
    "Who are you?" "No one of consequence." "I must know." "Get used to disappointment."